Amrita Journal of Medicine最新文献_第8页

Ensuring Problem-Based Learning for Medical Students and Looking Forward to Developing Competencies 确保医学生以问题为基础的学习，并期待发展能力

Amrita Journal of Medicine Pub Date : 2022-01-01 DOI: 10.4103/AMJM.AMJM_55_21

M. Taywade, Kumbha Gopi, Debkumar Pal, B. Sahoo

引用次数: 0

Purple urine bag syndrome in acidic urine! 紫尿袋综合征中酸性尿!

Amrita Journal of Medicine Pub Date : 2021-10-01 DOI: 10.4103/AMJM.AMJM_42_21

Amit Katyal, Ananda Menon

引用次数: 0

New gepants against acute migraine: A systematic review and network meta-analysis 新患者抗急性偏头痛:系统回顾和网络荟萃分析

Amrita Journal of Medicine Pub Date : 2021-10-01 DOI: 10.4103/AMJM.AMJM_44_21

Dhyuti Gupta, S. Dhaneria, Alok Singh

{"title":"New gepants against acute migraine: A systematic review and network meta-analysis","authors":"Dhyuti Gupta, S. Dhaneria, Alok Singh","doi":"10.4103/AMJM.AMJM_44_21","DOIUrl":"https://doi.org/10.4103/AMJM.AMJM_44_21","url":null,"abstract":"Objectives: Recently two calcitonin gene-related peptide receptor antagonists (ubrogepant and rimegepant) were approved for the acute attack of migraine. This systematic review and network meta-analysis was performed, so as to evaluate and comprehend the effectiveness of both ubrogepant and rimegepant in alleviating the acute attack of migraine. Materials and Methods: An in-depth search was performed through Cochrane library, Pub Med, and clincialtrials.gov, for the period 2015–2019, using the key words: ubrogepant; rimegepant; and acute migraine. The randomized double-blind phase III clinical trials that explored the efficacy of these drugs were considered for inclusion in this review. The outcomes for this review were considered as the proportion of patients who had to resort to rescue medication within 24 h of taking either of the gepant, and the proportion of patients who had achieved sustained pain freedom and relief. In addition, an indirect meta-analysis was also conducted to establish the comparative effectiveness of these drugs. In addition, risk of bias and heterogeneity among the trials were also assessed to ascertain the strength of the trials. Results: A total of five placebo-controlled RCTs were included in this review. Altogether, both drugs demonstrated well in the parameters assessed. Rimegepant was better than ubrogepant, as a lesser proportion of patients used rescue medication by 3.4%, and a significantly higher number of patients achieved sustained pain freedom by 2.1% at 2–24 h. In sustained pain relief at 2–24 h, rimegepant was slightly better than ubrogepant by 0.5%. Hence, rimegepant 75 mg emerged to be better in all outcomes. Conclusions: Both gepants proved to be efficacious in alleviating the acute attack of migraine. Rimegepant displayed superiority over the ubrgepant.","PeriodicalId":138060,"journal":{"name":"Amrita Journal of Medicine","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117214286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of video-assisted anal fistula treatment (VAAFT) and its adjuncts in the treatment of a cohort of patients with recurrent fistula-in-ano 视频辅助肛瘘治疗(VAAFT)及其辅助治疗复发性肛瘘患者队列的有效性

Amrita Journal of Medicine Pub Date : 2021-10-01 DOI: 10.4103/AMJM.AMJM_49_21

Vaishnavi Gunasekharan, Nanthesh Kumaran, A. Krishnan, Sanju Samuel, Anoop Vasudevan Pillai, R. Menon

{"title":"Effectiveness of video-assisted anal fistula treatment (VAAFT) and its adjuncts in the treatment of a cohort of patients with recurrent fistula-in-ano","authors":"Vaishnavi Gunasekharan, Nanthesh Kumaran, A. Krishnan, Sanju Samuel, Anoop Vasudevan Pillai, R. Menon","doi":"10.4103/AMJM.AMJM_49_21","DOIUrl":"https://doi.org/10.4103/AMJM.AMJM_49_21","url":null,"abstract":"Recurrence of disease after surgery for fistula occurs in approximately 30%–40% of patients. Treatment of a recurrent fistula has an increased risk of failure and further recurrence. The aim of this study was to find out the effectiveness of video-assisted anal fistula treatment (VAAFT) in the treatment of recurrent fistula and also to compare the effect of the two adjuvants, fibrin and platelet-rich fibrin (PRF), in reducing recurrence in a recurrent fistula. A retrospective observational study was done on a cohort of patients with fistula-in-ano being treated at our center between 2015 and 2021. Of 85 patients that underwent VAAFT, 36 had recurrent disease and were allotted to two groups, one group receiving fibrin and the other PRF. Details of patients were collected from the hospital database and by telephonic interview. To test the statistical significance of the difference in the proportion of categorical variables between two groups, chi-square test was used and Mann–Whitney U test for the difference in the mean-time of healing between two groups. Recurrence rate following VAAFT in patients with recurrent fistula-in-ano in our series was found to be 25%. A significant reduction in recurrence was noted in patients who received PRF as adjunct when compared to patients who received fibrin glue as adjunct (P = 0.0023). VAAFT is an excellent cost-effective choice for the management of recurrent fistula-in-ano. Use of PRF along with VAAFT improves the outcome of the procedure.","PeriodicalId":138060,"journal":{"name":"Amrita Journal of Medicine","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129285683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An extensive anterior abdominal wall Meleney’s gangrene following bull gore injury 牛血损伤后广泛腹壁梅勒尼坏疽

Amrita Journal of Medicine Pub Date : 2021-10-01 DOI: 10.4103/AMJM.AMJM_31_21

J. Pandiaraja

引用次数: 0

Assessment of dental fluorosis and dental caries among 8–16-year-old schoolchildren in Kanpur rural region, Uttar Pradesh 北方邦坎普尔农村地区8 - 16岁学童氟斑牙和龋齿的评估

Amrita Journal of Medicine Pub Date : 2021-10-01 DOI: 10.4103/AMJM.AMJM_33_21

Rohan Sachdev, Kriti Garg, Samiksha Shwetam, Aaryan Srivastava

{"title":"Assessment of dental fluorosis and dental caries among 8–16-year-old schoolchildren in Kanpur rural region, Uttar Pradesh","authors":"Rohan Sachdev, Kriti Garg, Samiksha Shwetam, Aaryan Srivastava","doi":"10.4103/AMJM.AMJM_33_21","DOIUrl":"https://doi.org/10.4103/AMJM.AMJM_33_21","url":null,"abstract":"Context: Dental caries remains a major public health problem, affecting 60-90% of school children. The assessment of dental caries and fluorosis in endemic fluoride areas will facilitate in assessing the relation between fluoride concentrations in water with dental caries, dental fluorosis simultaneously. Aims: The aim of the following study is to assess the dental caries and dental fluorosis prevalence among 8–16-year-old school children in Kanpur rural region, Uttar Pradesh. Settings and Design: This was a cross-sectional study. Materials and Methods: School children, residing in the village since childhood, in the age group of 8–16 years were selected from government schools. School children were categorized in five age groups and were examined for oral examination of available 8–16-year-old children fulfilling the inclusion and exclusion criteria was carried out to assess dental caries and fluorosis. Statistical Analysis Used: The influence of demographic characteristics on caries and fluorosis was tested using Chi square test, independent sample t-test and one-way ANOVA wherever applicable. Spearman rank correlation was applied to analyze the relationship between decayed teeth and dental fluorosis. Results: The caries prevalence was found to be 84.7%. Out of 1565 school children, 53.4% were males and 46.5% were females. The prevalence of dental fluorosis was found to be 87.5%.The fluorosis prevalence increased with increasing fluoride concentration with no difference in gender and age distribution. Conclusions: Children and teenagers are the most typically damaged by dental caries and fluorosis, it is necessary for the management of the prevalence of caries and fluorosis.","PeriodicalId":138060,"journal":{"name":"Amrita Journal of Medicine","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116151881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolic acidosis and cardiovascular function in chronic kidney disease: A review 慢性肾脏疾病代谢性酸中毒与心血管功能:综述

Amrita Journal of Medicine Pub Date : 2021-10-01 DOI: 10.4103/AMJM.AMJM_47_21

P. Uduagbamen

引用次数: 0

Zinc and Mucormycosis: Fact versus myth check 锌和毛霉病:事实与神话的检验

Amrita Journal of Medicine Pub Date : 2021-10-01 DOI: 10.4103/AMJM.AMJM_46_21

S. Sasidharan, H. Dhillon

引用次数: 0

Percutaneous retrieval of an embolized chemoport catheter from right side of heart using novel technique 应用新技术从心脏右侧经皮取出栓塞化疗导管

Amrita Journal of Medicine Pub Date : 2021-10-01 DOI: 10.4103/AMJM.AMJM_38_21

A. Singhal, Sudhir Kumar, Sudhir Joshi

引用次数: 0

“Booster vaccine” to mitigate the threat of “emerging COVID-19 variants”: A short review 减轻“新出现的COVID-19变体”威胁的“加强疫苗”:简要回顾

Amrita Journal of Medicine Pub Date : 2021-10-01 DOI: 10.4103/AMJM.AMJM_5_22

M. Pandian, P. Veepanattu, M. Moni, D. Sathyapalan

{"title":"“Booster vaccine” to mitigate the threat of “emerging COVID-19 variants”: A short review","authors":"M. Pandian, P. Veepanattu, M. Moni, D. Sathyapalan","doi":"10.4103/AMJM.AMJM_5_22","DOIUrl":"https://doi.org/10.4103/AMJM.AMJM_5_22","url":null,"abstract":"Vaccination is the time-tested strategy in controlling the infectious diseases. The global scientific community has agreed upon the role of mass vaccination, as a strategy in abating the ongoing COVID pandemic. By immunizing the at-risk population vaccination aims not only to break the chain of spread of disease but also reduces the severity of the disease, hospitalization, and mortality. In the wake of waning immunity and emerging variants, spreading the world over its time to review the evidence of a third dose as a booster.When deciding on the booster dose, availability of the vaccine, type of vaccine, circulating SARS-CoV-2 variants, and emerging variants have to be taken into consideration. Booster dose as the name suggests boosts the waning immunity of the population and when implemented as a public health measure has the potential to increase the antibody level of the population beyond a threshold, thereby mitigating the spread of COVID infection. Cross-protection is likely to the newly emerging SARS-CoV-2 variants by virtue of the enhanced immune response. However, to develop robust recommendations, investigations on the effectiveness and cost-effectiveness of booster doses vaccines are needed in the context of rapidly spreading variant, the omicron.","PeriodicalId":138060,"journal":{"name":"Amrita Journal of Medicine","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128874108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0