International Journal of Animal Science and Technology最新文献

{"title":"Social Dynamics of Exotic Dama Gazelles <i>(Nanger dama)</i> on Texas Ranch Land","authors":"Elizabeth Cary Mungall, Susan Margaret Cooper","doi":"10.11648/j.ijast.20220601.12","DOIUrl":"https://doi.org/10.11648/j.ijast.20220601.12","url":null,"abstract":"This project examines social dynamics of North African dama gazelles (Nanger dama ruficollis) under different combinations in a large, 202 ha, rangeland pasture in Central Texas, USA. There are many wildlife ranches in this part of Texas that keep herds of these critically endangered dama gazelles. Therefore, an increased understanding of how these pasture animals may assort themselves under different social combinations can not only help managers sustain and grow their herds but also bolster the numbers that give the species a better chance to remain viable while status in their native countries remains precarious. Investigated were: (1) 7 adult females with one adolescent male and one young adult male, (2) the same adult females and immature male without any adult males, (3) the same adult females and the young, now maturing, male with multiple adult males. It was shown that multiple adult males can co-exist in large pastures with minimal aggression, even when females are present, provided there is informed management. All the gazelles wore GPS-radio collars (7 adult females, 1 immature male, and 1-to-3 adult males depending on phase of the project). Locations were recorded every 3 hr. Visual observations were made monthly. Project duration was December 19, 2014, until June 30, 2016. Without the initial adult male, the female herd split and association values declined. With new adult males added, 2 divided the pasture, thus, separating spatially. The maturing male kept his core area where the main female group stayed, but now separated temporally. Adult males focused on areas favored by females but did not direct the movements of the females. These males did not associate as closely with females as females did with each other. Estimating maximum possible adult males for a pasture must allow for slope, vegetation density, and sites favored by females. The only two similar studies determined larger core areas under more xeric conditions, but these other studies could not assess group dynamics in detail without collars on more animals.","PeriodicalId":13766,"journal":{"name":"International Journal of Animal Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78020516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment on Challenges and Opportunities of Beef Cattle Production in Hawa Gelan District, Kellem Wollega Zone, Western Oromia, Ethiopia","authors":"M. Yousuf, A. Yusuf","doi":"10.11648/j.ijast.20220601.13","DOIUrl":"https://doi.org/10.11648/j.ijast.20220601.13","url":null,"abstract":"Pork farm animals have massive function in imparting protein meals for consumers. The take a look at become performed in Hawa Gelan district, Kellem Wollega Zone Western Oromia Ethiopia with the goal to Assessment on Challenges and Opportunities of Beef Cattle Production. Assessment on challenges and opportunities of beef cattle production was carried out on 80 farmers in the study district. Majority of the respondents has been used blended manufacturing device (50%) due to the fact maximum of the red meat farm animals manufacturers had been they take part in crop manufacturing, farm animals rearing sports and dealer game. The end result of this take a look at shows that 45% of the respondents rely upon herbal pasture, 22.5% of crop residues, 15% of sparkling grass cutting, 7.5% of sugar cane and 10% of maize grain as a basal feed for his or her farm animals. Price willpower for pork farm animals advertising and transactions on the look at place 87.5% have been through the negotiation among the sellers/manufacturers and the customers and 12.5% of the respondents said that agents intervene among the sellers/manufacturers and the customers. The foremost water supply is determined from river water, faucet water and ponds. The supply of livestock for fattening had been majorly from marketplace (purchasing, 78.75%), whilst the rests had been from personal herd 10% and 11.25% from both. Feed scarcity, feed cost, land scarcity, insufficient housing, genetic aspect and occurrence of illnesses like blackleg disease, lumpy pores and skin disease, Pasteurellosis, Anthrax, Bloating and Parasites are the foremost demanding situations for pork farm animals manufacturing. The root reasons of feed scarcity had been loss of land, excessive fee of feed and occasional great and amount of feed supplementation. When the manufacturer receives the land that used for forage manufacturing they must be use advanced forage. The authorities must paintings on introducing excessive feed yielder forage and must forage improvement techniques specifically outside forage manufacturing gadget to be able to clear up the feed scarcity in phrases of great and amount. Government must enhance advertising linkage of the pork farm animal’s products. In the destiny the limitations cited at the take a look at region must be solved via way of means of the authorities in collaboration with all stake holders and the possibilities must be improve above these.","PeriodicalId":13766,"journal":{"name":"International Journal of Animal Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73617906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pengaruh Pemberian Tepung Daun Mengkudu (Morinda citrifolia) terhadap Pertambahan Bobot Badan Ayam Kampung di Desa Ngayung Kecamatan Maduran Kabupaten Lamongan","authors":"Andi Saputro, Nuril Badriyah, Qabilah Cita Sumarsono","doi":"10.30736/asj.v4i04.73","DOIUrl":"https://doi.org/10.30736/asj.v4i04.73","url":null,"abstract":"Tanaman obat yang dimanfaatkan sebagai bahan campuran pada ransum unggas belum banyak dilakukan meskipun telah banyak digunakan oleh manusia, perlu dilakukan pengujian mengingat permintaan serta preferensi konsumen yang semakin kritis pada bahan makanan yang dikonsumsi. Pengumpulan data penelitian dilakukan mulai 1 maret sampai 30 maret 2021 di kandang bapak Mukarap Desa Ngayung kecamatan Maduran Kabupatan Lamongan. Riset bertujuan guna mengetahui pengaruh pemberian tepung daun mengkudu pada ransum terhadap bobot badan ayam kampung. Hasil penelitian diharapkan mampu digunakan sebagai informasi mengenai penggunaan tepung daun mengkudu pada level berapa sehingga menambah nafsu makan yang memiliki guna meningkatkan bobot badan ayam kampung. Materi riset yakni ayam kampung yang berada di kandang bapak Mukarap Desa Ngayung Kecamatan Maduran Kabupatan Lamongan sebanyak 36 ekor ayam kampung yang berumur 3 bulan. Riset menggunakan metode percobaan dengan Rancangan acak lengkap yang terdiri dari 4 perlakuan serta 3 ulangan, adapun perlakuan tersebut yakni dengan pemberian tepung daun mengkudu 5%, 10%, 15% dari ransum. Selama penelitian variabel yang diamati yakni penambahan bobot badan ayam kampung dengan varian kemudian dilanjut dengan uji beda nyata terkecil. Hasil riset menunjukkan bahwa bobot badan ayam kampung berbeda sangat nyata pada taraf signifikan 5% (P<0,05 ) dan 1% (P<0,01). Sedangkan pada konsumsi pakan tidak berbeda nyata pada taraf signifikan 5% dimana F hitung 0,271 lebih kecil dari F tabel 1% (4,07) terhadap konsumsi pakan. Percobaan ini merekomendasikan bahwa tepung daun mengkudu dapat diberikan sebanyak 10% terhadap ransum ayam kampung agar mendapat performan dan produktifitas yang optimal.","PeriodicalId":13766,"journal":{"name":"International Journal of Animal Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84605928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analisa Tata Niaga dan Keuntungan Pemasaran Sapi Potong di Koperasi Ternak Gunungrejo Makmur Kecamatan Kedungpring Kabupaten Lamongan","authors":"Sonny Isnanda Adi Pratama, M. Dahlan, Alfian Adi Atma","doi":"10.30736/asj.v4i04.77","DOIUrl":"https://doi.org/10.30736/asj.v4i04.77","url":null,"abstract":"Tata niaga Pemasaran pada sektor peternakan sebagai salah satu kegiatan lanjutan dari proses produksi, kegiatan pemasaran berperan penting pada sektor peternakan, pemasaran dibutuhkan dalam menyampaikan produk langsung pada konsumen. Penelitian ini bertujuan untuk mengetahui saluran tata niaga, margin keuntungan/pemsaran, dan tingat efisiensi saluran tata niaga oleh peternak dan jagal sapi potong di Koperasi ternak Gunungrejo Makmur Kecamatan Kedungpring Kabupaten Lamongan. Metode penelitian menggunakan survey. Hasil penelitian menunjukkan bahwa Saluran pemasaran sapi potong di Koperasi Gunungrejo Makmur Kecamatan Kedungpring Kabupaten Lamongan terdapat 3 pola saluran pemasaran. Dari seluruh pola pemasaran I, II, dan III total margin paling tinggi diperoleh pada saluran pemasaran III yaitu sebesar Rp.18.300/kg, sedangkan total margin pemasaran paling rendah diperoleh pada saluran I sebesar Rp.13.900/kg.","PeriodicalId":13766,"journal":{"name":"International Journal of Animal Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84539082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Persepsi Masyarakat terhadap Polusi Pengembangan Ternak Itik Di Kecamatan Turi Kabupaten Lamongan","authors":"A. Fadhilah, M. Dahlan, Alfian Adi Atma","doi":"10.30736/asj.v4i04.75","DOIUrl":"https://doi.org/10.30736/asj.v4i04.75","url":null,"abstract":"Penelitian ini bertujuan untuk mengetahui bagaiamana persepsi masyarakat terhadap polusi pengembangan ternak itik di Desa Tawang Rejo di kecamatan Turi. Menggunakan metode purposive sampling di tentukan menggunakan rumus slovin dikarenakan peternak dilokasi Tawangrejo memiliki populasi 240 orang Hasil penilitian menujukkan bahwa jumlah skor sebanyak 924 untuk persepsi masyarakat secara keseluruhan skor (904,7-1117,5) termasuk kategori terganggu. Dari hasil tersebut bahwa responden merasa terganggu dengan keberadaan peternakan Itik yang berada ditengah pemukiman penduduk serta kurang memperhatikan kebersihan kandang.","PeriodicalId":13766,"journal":{"name":"International Journal of Animal Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81149455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pengaruh Penambahan Tepung Kunyit (Curcuma Domestica val) terhadap Kualitas Fisik Telur Burung Puyuh (Coturnix-coturnix Japonica)","authors":"M. Syaifudin, Nuril Badriyah, Anik Fadlillah","doi":"10.30736/asj.v4i04.74","DOIUrl":"https://doi.org/10.30736/asj.v4i04.74","url":null,"abstract":"Penelitian bertujuan guna mengetahui pengaruh penambahan tepung tepung kunyit (Curcuma domestica val) pada pakan komersil terhadap kualitas fisik telur puyuh (Cortunix cortunix japonica) dilihat dari tebal kerabang, warna kuning telur, indeks kuning telur, indeks telur serta Haugh Unit telur puyuh. Materi pada riset yakni telur puyuh yang dihasilkan dari burung puyuh ras hitam yang diberikan ransum pakan komersial dan pakan tambahan tepung kunyit. Penelitian memakai metode Analisa laboratorium dengan Rancangan Acak Kelompok (RAK) diantaranya empat macam perlakuan serta ulangan lima kali dengan penambahan 100%+0%, 97%+3, 96%+4%, dan 95%+5%. Variabel yang di amati pada penelitian yakni Mengamati kualitas fisik telur diantaranya tebal kerabang, warna kuning telur, Indeks kuning telur,  Indeks telur, serta Haugh unit telur puyuh. Perolehan data kemudian ditabulasi serta dianalisa dengan analysis of variance (ANOVA). Apabila ada perbedaan, dilakukan Uji Jarak Berganda Duncan (UJBD) guna mengetahui perlakuan yang paling baik. Hasil penelitiaan menunjukkan bahwa tepung kunyit dengan pemberian taraf (3%,4%, dan 5%) pada pakan komersial tidak memberi pengaruh terhadap kualitas fisik (tebal kerabang, indeks kuning telur, indeks telur, haugh unit telur) tetapi memberikan pengaruh yang nyata pada warna kuning burung puyuh (Coturnix coturnix japonica). Tepung kunyit yang ditambahkan pada pakan komersial mengasilkan nilai rataan tebal kerabang telur puyuh yakni 0,392 – 0,444 mm. Nilai rataan skor warna kuning telur puyuh adalah 4,627 – 5,640. Nilai rataan indeks kuning telur puyuh adalah 0,434 – 0,441. Rataan nilai indeks telur puyuh adalah 77,784 – 78,794%. Nilai rataan haugh unit telur puyuh adalah 86,583 – 91,227.","PeriodicalId":13766,"journal":{"name":"International Journal of Animal Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79657708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analisis Tata Niaga Telur Puyuh Milik Bapak Budi di Desa Lopang Kecamatan Kembangbahu Kabupaten Lamongan","authors":"Sarvian Taat, Edy . Susanto, M. Qomaruddin","doi":"10.30736/asj.v4i04.76","DOIUrl":"https://doi.org/10.30736/asj.v4i04.76","url":null,"abstract":"Tujuan dari penelitian ini iyalah untuk memahami alur dsitribusi tataniaga telur puyuh milik bapak budi, unsur-unsur pemasaran yang terlibat, share keuntungan yang di dapat pedagang dan efisiensi pemasaran yang di peroleh peternak telur puyuh. Metode yang digunakan yakni metode sampling (purposive random sampling dan proposional random sampling. Data di dapat dengan melaksanakan observasi dan interview langsung kepada peternak beserta unsur yang terlibat dalam pemasaran. kemudian dianalisis secara deskriptif dan kuantitatif. Hasil penelitian ini menunjukkan bahwa alur distribusi yang terbentuk terdapat satu pola yaitu pola I. untuk pola I didominasi pedagang besar (pengepul), pasar (penjual dan pengecer), peagang pengecer (toko) kemudian konsumen. Unsur-unsur pemasaran yang terlibat diantaranya  adalah Peternak telur puyuh  ( produsen) - Pedagang Besar (prngepul)-Pasar (penjual dan pengecer)-pedagang pengecer (toko) dan konsumen. Share keuntungan yang diperoleh pedagang tertinggi adalah pedagang pasar (penjual dan pengecer) yakni sebesar (7,0%) dikarenakan pedagang ini membeli telur puyuh dari pedagang besar (pengepul) dengan harga Rp. 21,000/Kg. Kemudian dijual kembali kepada konsumen akhir/konsumen di pasar maupun kepada pedagang pengecer (toko) dengan harga Rp.22.000/Kg (menyesuaikan harga pasar), Sedangkan  Share keuntungan terendah di peroleh pedagang pengecer (toko) dikarenakan unsur ini membeli telur puyuh dengan harga Rp. 22.000 – 23.000/Kg dari pedagang pasar (penjual dan pengecer) dan dijual kembali kepada konsumen dengan harga Rp.22.000-2300/Kg + kerugian yang didapat karna kebusukan telur maupun pecah saat perjalanan, jadi semakin besar populasi ternak maka semakin efisien pemasaran yang diterima oleh peternak.","PeriodicalId":13766,"journal":{"name":"International Journal of Animal Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87336765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of Agropastoralist Production Systems and the Potential for Improving Livestock Productivity with Improved Feeding in Western Burkina Faso","authors":"M. Kere, Vinsoun Millogo, A. Koné, N. Joshi, R. Burdick, T. Harrigan, A. Srivastava, G. Ouédraogo","doi":"10.11648/J.IJAST.20210504.12","DOIUrl":"https://doi.org/10.11648/J.IJAST.20210504.12","url":null,"abstract":"The major constraint of livestock farming in Burkina Faso is the feed gap. This study aims to provide information on feed resources, availability, and uses in Bama's district. Feed Assessment Tool (FEAST) was used to evaluate feed resources and to generate possible interventions. Focus groups were held and took into account 140 farmers, of which 90 were recalled for individual surveys. We found that the Bama district was characterized by agropastoral production systems in which crop provides 65.1% of household income whereas 23.9% was from livestock. Livestock feeding throughout the year depended on natural grazing. Natural pastures contributed most often to dry matter, metabolizable energy, and crude protein in animals' total diet, respectively, with 65.4, 64.4, and 61.5%. In addition to grazing, crop residues were collected after harvest to form a dietary supplement for the animals. The study also revealed nutritional gaps, and farmers were purchasing concentrates to compensate and ensure the best livestock productivity. The dominant complement purchased was cotton cake at a rate of 623.1 kg/year/household. None of the agropastoralists grew fodder crops. Identified interventions able to improve productivity and production of animals were supplementations with: a high-energy supplement (molasses); protein byproducts; pruning products, aerial parts, and leaf-stripping without sacrificing grain/tuber yields; cereal byproducts (rice bran, corn, wheat); multi-nutritional blocks; and commercially balanced feed. Given the food shortage, especially in the dry season, better management of food resources through the collection and conservation of fodder and the adoption of forage crops could increase feed availability.","PeriodicalId":13766,"journal":{"name":"International Journal of Animal Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88021940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Millet and Sorghum as Possible Dietary Energy Sources in the Diet of Japanese Quails","authors":"M. Aminu, L. Adamu, A. Iliya, Sudik Samuel David, Dunya Maina Amos, Adejumo Iseaac Oluseun, M. John, Hanafi Yusuf, Bomoi Abubakar Sule","doi":"10.11648/J.IJAST.20210504.11","DOIUrl":"https://doi.org/10.11648/J.IJAST.20210504.11","url":null,"abstract":"An experiment was conducted to assess the effect of millet and sorghum as alternatives to maize. on performance and egg production parameters of quails. Three hundred (300) day old quails were sourced form National Veterinary Institute Jos. The birds were brooded for two weeks and randomly allotted to three (3) different energy sources i.e. maize, millet and sorghum designated as treatment 1, 2 and 3 respectively. The birds were fed with experimental diets for six months. Results showed daily feed intake (68.35-79.86), daily weight gain (3.41-3.43) and feed conversion ratio (3.33-3.91) were not affected by the different energy sources (P>0.05). Most of the carcass parameters were statistically similar (P>0.05). The hen day egg production (80.21-84.51) and egg production parameters were not affected by the alternative energy sources (P>0.05), similarly hematological parameters showed that packed cell volume (50.20-56.00), red blood cells (4.72-5.21) and hemoglobin (16.98-18.38) were statistically similar (P>0.05). The serum biochemical parameters showed that total protein (36.20-39.80), globulins (11.60-14.44), total protein (36.20-39.80), glucose (12.68-14.82), cholesterol (5.36-6.78), urea (17.80-20.00) and ASAT (1.98-2.08) were not affected by the different energy sources (P>0.05). I It can be concluded that millet and sorghum can be alternative energy sources in quail production in semi-arid environment of Gashua Yobe state with reduction in cost of production.","PeriodicalId":13766,"journal":{"name":"International Journal of Animal Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74915708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hearing Toxicity Induced by Tripterygium Glycosides in Zebrafish","authors":"Huifang Xu, Xuxia Tang, Jingjing Chen, Yanfen Shi, Jun Liu, Guo Shengya, Zhou Jiali, Li Chunqi, Jinggeng Zhou","doi":"10.11648/J.IJAST.20210503.15","DOIUrl":"https://doi.org/10.11648/J.IJAST.20210503.15","url":null,"abstract":"Tripterygium glycosides (TG) is isolated from an extensively used traditional Chinese medicine herb tripterygium roots and has been extensively used in the treatment of rheumatoid arthritis, nephrotic syndrome, hyperthyroidism and other diseases due to its anti-inflammatory and immunosuppressive effects. Hearing toxicity has been recently associated with TG use in human patients. In this study, authors assessed hearing toxicity and possible molecular toxic mechanisms of TG in a whole animal model. The maximum non-lethal concentration (MNLC) of TG on the zebrafish was 21 mg/L. TG induced zebrafish hair cell loss in a dose-dependent manner (p<0.001), and the saccular otolith size reduction when treated at MNLC (p<0.01). TG treatment resulted in sound-stimulated zebrafish movement reduction (p<0.001); and the rollover zebrafish percentages were elevated as TG treatment concentrations moved up. Following TG treatment, mRNA levels of the zebrafish hearing organ development genes eya1 and val were remarkably downregulated, and the expression of apoptosis-associated genes bax and caspase3 was significantly enhanced (p<0.05). These findings confirm the hearing toxicity of TG and suggest its toxic mechanisms probably are through suppressing hearing cell development and promoting hearing cell apoptosis. Authors recommend zebrafish assay as a quick and reliable screening test of hearing toxicity for drugs and health products.","PeriodicalId":13766,"journal":{"name":"International Journal of Animal Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74747295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}