British Journal of Surgery最新文献

{"title":"Liver transplantation for locally advanced non-resectable intrahepatic cholangiocarcinoma treated with neoadjuvant therapy: early results from the TESLA trial.","authors":"Sheraz Yaqub, Sondre Busund, Tor Magnus Smedman, Trygve Syversveen, Ammar Khan, Jon Magnus Solheim, Trine Folseraas, Kristine Wiencke, Kristoffer Lassen, Svein Dueland, Pål-Dag Line","doi":"10.1093/bjs/znaf054","DOIUrl":"10.1093/bjs/znaf054","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 3","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11914714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laparoscopic distal pancreatectomy with en-bloc coeliac axis resection guided by augmented reality navigation.","authors":"Xinci Li, Haisu Tao, Chihua Fang, Jian Yang","doi":"10.1093/bjs/znae331","DOIUrl":"10.1093/bjs/znae331","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 3","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143707924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrence patterns and post-recurrence survival of patients with bilobar colorectal liver metastases: international multicentre retrospective study.","authors":"","doi":"10.1093/bjs/znaf003","DOIUrl":"https://doi.org/10.1093/bjs/znaf003","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 3","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Routine anaesthesia ward-based patient visits in surgery: 1-year outcomes of the TRACE randomized clinical trial.","authors":"Valérie M Smit-Fun, Dianne de Korte-de Boer, Thomas Damen, Annick Stolze, Linda M Posthuma, Markus W Hollmann, Wolfgang F F A Buhre","doi":"10.1093/bjs/znaf019","DOIUrl":"10.1093/bjs/znaf019","url":null,"abstract":"<p><strong>Background: </strong>The TRACE (Routine posTsuRgical Anaesthesia visit to improve patient outComE) RCT did not show any perioperative benefit from ward-based visits by anaesthetists after surgery. The aim of this study was to evaluate the impact of this intervention on longer-term outcomes.</p><p><strong>Methods: </strong>Patients were followed up in the TRACE RCT to 1 year in nine hospitals in the Netherlands. Patients undergoing elective non-cardiac surgery, and at risk for adverse postoperative outcome, were included. Patients in the intervention group additionally received routine anaesthesia visits on postoperative days 1 and 3. Clinical outcome measures included 1-year mortality, hospital readmission, and reoperation. Functional recovery (FR) was measured using the patient-reported global surgical recovery (GSR) index, ability to perform activities of daily living (ADL), and functional recovery index (FRI). Quality of life (QoL) was measured using EQ-5D-5L.</p><p><strong>Results: </strong>Some 5473 adult patients were followed up. No differences were found between the control and intervention groups for clinical, FR, and QoL outcome measures. One-year mortality was 5.4% in the control group and 5.8% in the intervention group, readmission was 27% and 26% respectively, and reoperation was 20% and 18% respectively. At 1 year, FR and QoL had recovered to preoperative levels. However, 30% of patients were not able to fully perform ADL and 40%-51% of patients still reported a problem in the EQ-5D-5L dimensions mobility, usual activities, and pain/discomfort.</p><p><strong>Conclusion: </strong>Routine postoperative anaesthesia ward visits of patients did not improve clinical, functional, and QoL outcomes. A substantial proportion of patients still experienced health-related limitations in daily life 1 year after surgery. In conclusion, an early postoperative intervention with postoperative anaesthesia visits in the ward after non-cardiac surgery had no effect on 30-day or 1-year clinical outcome. Remarkably, TRACE shows that compared with data sampled 10 years ago, 1-year mortality has not improved in the Netherlands. At 1 year, functional recovery or QoL showed little improvement compared with baseline. Importantly, a substantial number of patients still reported incomplete recovery and problems that limit QoL, which indicate that there is still room for improvement.</p>","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 3","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11897594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laparoscopic total pelvic exenteration: a simplified procedure using the fascial space priority approach.","authors":"Hongjie Yang, Yuanda Zhou, Peishi Jiang, Jiafei Liu, Zhichun Zhang, Qingsheng Zeng, Peng Li, Yu Long, Xipeng Zhang, Yi Sun","doi":"10.1093/bjs/znae316","DOIUrl":"https://doi.org/10.1093/bjs/znae316","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 3","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143661653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parathyroid vascular anatomy using intraoperative mapping angiography: the PARATLAS study.","authors":"Fares Benmiloud, Neil Tolley, Anne Denizot, Aimee Di Marco, Frederic Triponez","doi":"10.1093/bjs/znae307","DOIUrl":"10.1093/bjs/znae307","url":null,"abstract":"<p><strong>Background: </strong>Understanding vascular anatomy of the parathyroid glands (PG) is crucial during thyroidectomy. The aim of this study was to describe patterns and distribution of parathyroid vessels.</p><p><strong>Method: </strong>An analysis of all intraoperative mapping angiographies from indocyanine green injection and fluorescence imaging in patients undergoing thyroid surgery between February 2020 and September 2021. The parathyroid vessels were classified according to the pattern of contact with the thyroid. Data collection and analysis were carried out in accordance with MR004 reference methodology.</p><p><strong>Results: </strong>A total of 200 angiographies from 196 patients were analysed (159 female/37 male, mean(s.d.) age: 54.2 ± 13.7 years), and 320 PGs were assessed. The parathyroid vessels had no contact with the thyroid in 20 (6%; Type 0), a single-point of contact in 74 (23%; Type 1), a posterior path in 47 (15%; Type 2), a lateral path in 68 (21%; Type 3), an intrathyroidal path in 19 (6%; Type 4), and a possible medial path in 26 (8%; Type X1) cases. The course of the vessels was unclear in 36 cases (11%; Type X2). Spatial distribution analysis showed a concentration of superior parathyroid vessels around Zuckerkandl's tubercle, whereas the distribution of the inferior parathyroid vessels was anterior and sparse.</p><p><strong>Conclusion: </strong>Intraoperative mapping angiographies help to define the main patterns of the parathyroid vessels according to their contact with the thyroid and provide surgically useful information about spatial vessel distribution.</p>","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 3","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11894526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of PD1 blockade added to neoadjuvant chemoradiotherapy on rectal cancer surgery: post-hoc analysis of the randomized POLARSTAR trial.","authors":"Kai Pang, Xinzhi Liu, Hongwei Yao, Guole Lin, Yuanyuan Kong, Ang Li, Jiagang Han, Guoju Wu, Xin Wang, Yingjiang Ye, Jie Zhang, Guangyong Chen, Aiwen Wu, Yi Xiao, Yingchi Yang, Zhongtao Zhang","doi":"10.1093/bjs/znaf057","DOIUrl":"10.1093/bjs/znaf057","url":null,"abstract":"<p><strong>Background: </strong>The addition of PD1 blockade to neoadjuvant chemoradiotherapy (CRT) has been shown to significantly increase pCR rates in locally advanced rectal cancer (LARC). Yet, its impact on total mesorectal excision (TME) remains unknown.</p><p><strong>Methods: </strong>A post-hoc analysis of the randomized POLARSTAR trial, which enrolled patients with LARC at eight major colorectal cancer centres in Beijing to compare neoadjuvant CRT plus PD1 blockade with CRT alone, was undertaken. Patients received one of three combinations of neoadjuvant treatments before TME surgery: CRT plus concurrent PD1 blockade (concurrent group), CRT plus sequential PD1 blockade (sequential group), and CRT alone (control group). Several parameters related to TME surgery were studied.</p><p><strong>Results: </strong>For the concurrent group, the sequential group, and the control group, 52, 46, and 45 patients respectively were included in this analysis. The proportion of patients undergoing sphincter-saving plus one-stage anastomosis surgery was 92% (48 of 52), 96% (44 of 46), and 87% (39 of 45) respectively. The proportion of patients without a stoma was 21% (11 of 52), 17% (8 of 46), and 11% (5 of 45) respectively. The grade 3/4 surgical complication rate was 4% (2 of 52), 7% (3 of 46), and 4% (2 of 45) respectively. Significant differences were observed between the sequential group and the control group with respect to the proportion of patients with TRG0 (37% versus 18% respectively; P = 0.040), ypT0/is ypN0 (39% versus 20% respectively; P = 0.046), and a low neoadjuvant rectal (NAR) score (54% versus 31% respectively; P = 0.025).</p><p><strong>Conclusions: </strong>Neoadjuvant CRT plus PD1 blockade enhances pathological tumour regression and is beneficial to the successful implementation of TME in patients with LARC. Validations with larger sample sizes are warranted.</p>","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 3","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143676690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-year follow-up of antibiotics versus placebo in adults with CT-confirmed uncomplicated acute appendicitis: a secondary analysis of the APPAC III randomized clinical trial.","authors":"Sami Sula, Suvi Sippola, Jussi Haijanen, Saija Hurme, Pia Nordström, Tero Rautio, Ville Sallinen, Paulina Salminen","doi":"10.1093/bjs/znaf016","DOIUrl":"https://doi.org/10.1093/bjs/znaf016","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 3","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urinary retention after laparoscopic low rectal cancer resection: post-hoc analysis of predictive factors in the GRECCAR 10 trial.","authors":"Jean-Luc Faucheron, Fatah Tidadini, Antoine Vilotitch, Alison Foote, Bertrand Trilling","doi":"10.1093/bjs/znae315","DOIUrl":"https://doi.org/10.1093/bjs/znae315","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 3","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient and tumour factors influencing length of sarcoma diagnostic trajectory intervals: first results from the international QUEST study.","authors":"","doi":"10.1093/bjs/znaf021","DOIUrl":"https://doi.org/10.1093/bjs/znaf021","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 3","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}