Internal and Emergency Medicine最新文献_第8页

Targeting Janus kinase 1 in refractory Behçet's disease: a case report on the clinical efficacy of upadacitinib. 靶向Janus激酶1治疗难治性behet病：upadacitinib临床疗效1例报告。

IF 3.2 3区医学

Internal and Emergency Medicine Pub Date : 2025-06-01 Epub Date: 2025-01-27 DOI: 10.1007/s11739-025-03874-x

Claudia Ammoscato, Federica Gatti, Florenzo Iannone, Giuseppe Lopalco

引用次数: 0

Eltrombopag treatment for thrombocytopenia in myelodysplastic syndromes: differences between responding and non-responding patients-a pilot study. 艾曲波帕治疗骨髓增生异常综合征血小板减少症：有反应和无反应患者的差异--一项试点研究。

IF 3.2 3区医学

Internal and Emergency Medicine Pub Date : 2025-06-01 Epub Date: 2024-10-31 DOI: 10.1007/s11739-024-03804-3

Roberto Castelli, Roberto Manetti, Gemma Lisa Sechi, Giorgio Lambertenghi Deliliers, Antonio Gidaro

引用次数: 0

Ultrasonographic assessment of gastric and gallbladder dynamics in human health and disease. 人类健康和疾病中胃和胆囊动力学的超声评价。

IF 3.2 3区医学

Internal and Emergency Medicine Pub Date : 2025-06-01 Epub Date: 2025-02-27 DOI: 10.1007/s11739-025-03905-7

Agostino Di Ciaula, Mohamad Khalil, Piero Portincasa

{"title":"Ultrasonographic assessment of gastric and gallbladder dynamics in human health and disease.","authors":"Agostino Di Ciaula, Mohamad Khalil, Piero Portincasa","doi":"10.1007/s11739-025-03905-7","DOIUrl":"10.1007/s11739-025-03905-7","url":null,"abstract":"The diagnosis of functional disorders of the upper gastrointestinal tract relies on clinical evaluation after exclusion of most frequent organic diseases. Diagnostic techniques contribute to better characterization of disease, choice of specific therapy, and follow-up. Functional ultrasonography was introduced in the early '80 s for the non-invasive study of gastric and gallbladder emptying without ionizing radiation, during fasting and postprandially. This technique detects dysfunctional motility in several gastrointestinal and systemic conditions, and can be used along with the assessment of real-time satiety and gastrointestinal symptoms after food ingestion, and dosing of hormones involved in the modulation of gastrointestinal and metabolic homeostasis. Functional ultrasonography has been increasingly used to explore the gastrointestinal pathophysiology, the gut-brain interaction, the effects of drugs (such as antidiabetics), the response to specific dietary and feeding patterns, and to support the development of nutraceuticals. In this evolving scenario, ultrasonography stands as a widely available, highly sustainable, non-invasive, repeatable, safe and low-cost tool, as compared with more expensive, less sustainable or still scarcely standardized procedures to study gastric and gallbladder motility as scintigraphy, wireless motility capsule tests, 13C breath tests, or magnetic resonance imaging. Functional ultrasonography not only provides reliable data in experimental protocols, but also in the assessment of clinical conditions as dyspeptic symptoms, diabetes, gastroenteric and neurological diseases, critical illness, and as a benchmark to evaluate the gastrointestinal effects of innovative drugs.","PeriodicalId":13662,"journal":{"name":"Internal and Emergency Medicine","volume":" ","pages":"965-983"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thyroid storm presenting with acute respiratory distress syndrome in a postpartum patient: a case report. 甲状腺风暴表现为急性呼吸窘迫综合征的产后患者：一个病例报告。

IF 3.2 3区医学

Internal and Emergency Medicine Pub Date : 2025-06-01 Epub Date: 2025-01-11 DOI: 10.1007/s11739-025-03858-x

Handan Özen Olcay, İzzettin Ertaş, Seda Dağar, Yunsur Çevik

引用次数: 0

Dream and its interpretation: scientific perspective. 梦及其解释：科学视角。

IF 3.2 3区医学

Internal and Emergency Medicine Pub Date : 2025-06-01 Epub Date: 2025-01-06 DOI: 10.1007/s11739-024-03849-4

Chukwuemeka O Eze

引用次数: 0

Assessing triage efficiency in Italy: a comparative study using simulated cases among nurses. 评估意大利的分诊效率：利用模拟病例对护士进行比较研究。

IF 3.2 3区医学

Internal and Emergency Medicine Pub Date : 2025-06-01 Epub Date: 2024-08-06 DOI: 10.1007/s11739-024-03735-z

Arian Zaboli, Francesco Brigo, Alessandro Cipriano, Serena Sibilio, Gabriele Magnarelli, Norbert Pfeifer, Michele Fratti, Fabio Malalan, Magdalena Massar, Michael Mian, Nicola Pagnucci, Gloria Brigiari, Lorenzo Ghiadoni, Gianni Turcato

{"title":"Assessing triage efficiency in Italy: a comparative study using simulated cases among nurses.","authors":"Arian Zaboli, Francesco Brigo, Alessandro Cipriano, Serena Sibilio, Gabriele Magnarelli, Norbert Pfeifer, Michele Fratti, Fabio Malalan, Magdalena Massar, Michael Mian, Nicola Pagnucci, Gloria Brigiari, Lorenzo Ghiadoni, Gianni Turcato","doi":"10.1007/s11739-024-03735-z","DOIUrl":"10.1007/s11739-024-03735-z","url":null,"abstract":"Background: Emergency Departments (EDs) across Italy use different triage systems, which vary from region to region. This study aimed to assess whether nurses working in different EDs assign triage codes in a similar and standardized manner.Methods: A multicenter observational simulation study involved the EDs of Bolzano Hospital, Merano Hospital, Pisa University Hospital, and Rovereto Hospital. All participating nurses were given 30 simulated clinical cases (vignettes) and asked to assign triage codes according to the triage systems used in their EDs. Subsequently, we assessed inter-rater agreement and evaluated if code assignment had different performance among hospitals in relation to different clinical outcomes.Results: Eighty-seven nurses participated in this study. There was marked variation in assigned triage codes both across hospitals and among individual operators. The kappa values for inter-rater agreement were 0.632 for Bolzano Hospital, 0.589 for Merano Hospital, 0.464 for Pisa University Hospital, and 0.574 for Rovereto Hospital. Sensitivity and specificity levels varied considerably for the same outcomes when comparing different hospitals.Conclusion: There is a high degree of subjectivity in triage code assignment by ED nurses. In the interest of equitable care for patients, this variability within the same country is hardly acceptable.","PeriodicalId":13662,"journal":{"name":"Internal and Emergency Medicine","volume":" ","pages":"1167-1176"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141893363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Total cholesterol and bilirubin levels are associated with neurologic outcomes in patients with out-of-hospital cardiac arrest. 总胆固醇和胆红素水平与院外心脏骤停患者的神经系统预后有关。

IF 3.2 3区医学

Internal and Emergency Medicine Pub Date : 2025-06-01 Epub Date: 2024-11-08 DOI: 10.1007/s11739-024-03742-0

Sang Hwan Lee, Yongil Cho, Jaehoon Oh, Hyunggoo Kang, Tae Ho Lim, Byuk Sung Ko, Kyung Hun Yoo, Juncheol Lee

{"title":"Total cholesterol and bilirubin levels are associated with neurologic outcomes in patients with out-of-hospital cardiac arrest.","authors":"Sang Hwan Lee, Yongil Cho, Jaehoon Oh, Hyunggoo Kang, Tae Ho Lim, Byuk Sung Ko, Kyung Hun Yoo, Juncheol Lee","doi":"10.1007/s11739-024-03742-0","DOIUrl":"10.1007/s11739-024-03742-0","url":null,"abstract":"Background: Assessing the neurologic outcomes of patients who experience out of hospital cardiac arrest (OHCA) is challenging. Neurologic outcomes were evaluated using initial nutrition related biochemical markers.Methods: We used data from a multicentre retrospective observational study, the Korean Cardiac Arrest Resuscitation Consortium (KoCARC) registry. Among the 666 patients, 217 had good neurologic outcomes, while 449 had poor neurologic outcomes. Multivariate logistic regression and classification and regression tree (CART) analyses were employed.Result: In the multivariate logistic regression analysis, total cholesterol ≥ 158.5 mg/dL, total bilirubin ≥ 0.265 mg/dL, Sodium < 142.1 mEq/L, AST < 200.5 U/L and were identified as significant biomarkers for good neurologic outcomes. In the CART analysis, total cholesterol ≥ 158.5 mg/dL and total bilirubin ≥ 0.365 mg/dL were found to be significant indicators. In additional analysis, when the total bilirubin level ranged from 0.6 to 0.7 mg/dL, the highest rate of a good neurologic outcome was observed at 44.6%, whereas levels below or above this range gradually indicated a lower rate of a good neurologic outcome.Conclusion: We propose that total cholesterol and total bilirubin levels could serve as valuable indicators for predicting neurologic outcomes in patients with OHCA.","PeriodicalId":13662,"journal":{"name":"Internal and Emergency Medicine","volume":" ","pages":"1185-1193"},"PeriodicalIF":3.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Echocardiographic clues of the "atrial pump mechanism" during cardiopulmonary resuscitation: comment. 心肺复苏过程中 "心房泵机制 "的超声心动图线索：评论。

IF 3.2 3区医学

Internal and Emergency Medicine Pub Date : 2025-06-01 Epub Date: 2024-11-07 DOI: 10.1007/s11739-024-03805-2

Sheng-En Chu, Jen-Tang Sun, Wen-Chu Chiang, Matthew Huei-Ming Ma

引用次数: 0

A 57-year-old woman with unexplained refractory shock. 一名57岁女性，不明原因的难治性休克。

IF 3.2 3区医学

Internal and Emergency Medicine Pub Date : 2025-06-01 Epub Date: 2025-01-22 DOI: 10.1007/s11739-025-03865-y

David Serantes Gómez, Amaia López de Lacalle, Beatriz Nieto Martino, David Bernal Bello

引用次数: 0

Hospital admission from the emergency department of adult patients affected by immune-mediated inflammatory diseases: a multidimensional retrospective analysis of an hospital-based cohort. 受免疫介导的炎症性疾病影响的成年患者急诊科入院：一项基于医院队列的多维回顾性分析

IF 3.2 3区医学

Internal and Emergency Medicine Pub Date : 2025-06-01 Epub Date: 2025-03-03 DOI: 10.1007/s11739-025-03899-2

Elisa Chapuis, Fetta Moussi, Antoine Dossier, Julien Rio, Arthur Mageau, Karim Sacre

引用次数: 0