Proceedings of MOL2NET'21, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 7th ed.最新文献

{"title":"Some ancestral Amazonian plants for health and nutrition","authors":"Manuel Pérez, W. Caicedo, L. Bravo, Ruth Arias, Matteo Radice, R. Abreu","doi":"10.3390/mol2net-07-11213","DOIUrl":"https://doi.org/10.3390/mol2net-07-11213","url":null,"abstract":"","PeriodicalId":136053,"journal":{"name":"Proceedings of MOL2NET'21, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 7th ed.","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126916739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Summary for PTML Chemoinformatics Linear Discriminant Analysis classification model for enantioselective reactions","authors":"Sha He","doi":"10.3390/mol2net-07-11203","DOIUrl":"https://doi.org/10.3390/mol2net-07-11203","url":null,"abstract":"Machine Learning (ML) is used to learn a system.","PeriodicalId":136053,"journal":{"name":"Proceedings of MOL2NET'21, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 7th ed.","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130805549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The State University of Amazonia as an intercultural scenario","authors":"Ruth Arias Gutiérrez, Manuel Lázaro Pérez Quintana","doi":"10.3390/mol2net-07-11204","DOIUrl":"https://doi.org/10.3390/mol2net-07-11204","url":null,"abstract":"","PeriodicalId":136053,"journal":{"name":"Proceedings of MOL2NET'21, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 7th ed.","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130869801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PTML Artificial Neural Network Chemoinformatics classification model for enantioselective reactions.","authors":"Shan He","doi":"10.3390/mol2net-07-11202","DOIUrl":"https://doi.org/10.3390/mol2net-07-11202","url":null,"abstract":"","PeriodicalId":136053,"journal":{"name":"Proceedings of MOL2NET'21, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 7th ed.","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116486756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DADNP: Dual Antibacterial Drug-Nanoparticle Systems Machine learning Approach","authors":"K. Diéguez-Santana","doi":"10.3390/mol2net-07-11196","DOIUrl":"https://doi.org/10.3390/mol2net-07-11196","url":null,"abstract":"Abstract. The rise of new infectious diseases, combined with an increase in antibiotic resistance among bacterial pathogens, poses a significant health danger to humans. This ever-increasing threat of bacterial resistance necessitates the development of novel techniques to overcome this barrier. One of the successful strategies for combating antibiotic resistance has been the conjugation of nanoparticles (NPs) with antimicrobial moieties such as antibiotics, peptides, or other biomolecules. However, Dual Antibacterial Drug-Nanoparticle (DADNP) discovery is a slow","PeriodicalId":136053,"journal":{"name":"Proceedings of MOL2NET'21, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 7th ed.","volume":"1062 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132155671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perturbation-Theory Machine Learning (PTML) Models for Predicting Metabolic Reaction Networks","authors":"K. Diéguez-Santana, G. Casañola-Martín, James R. Green, B. Rasulev","doi":"10.3390/mol2net-07-11195","DOIUrl":"https://doi.org/10.3390/mol2net-07-11195","url":null,"abstract":"","PeriodicalId":136053,"journal":{"name":"Proceedings of MOL2NET'21, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 7th ed.","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121117624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alanine and aspartate aminotransferase and urea concentrations in patients with degenerative spine disease","authors":"Marcin Gralewski, B. Grabarek, Dorian Gładysz, Rafał Staszkiewicz","doi":"10.3390/mol2net-07-11193","DOIUrl":"https://doi.org/10.3390/mol2net-07-11193","url":null,"abstract":"Abstract","PeriodicalId":136053,"journal":{"name":"Proceedings of MOL2NET'21, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 7th ed.","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128968795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobials from Native Lactic Acid Bacteria: A “Shotgun” Against Antibiotic-Resistant Staphylococcus aureus","authors":"G. Tenea, D. Olmedo, Pamela Ascanta, G. González","doi":"10.3390/mol2net-07-10913","DOIUrl":"https://doi.org/10.3390/mol2net-07-10913","url":null,"abstract":"Introduction The contamination of food by microorganisms, their persistence, growth, multiplication, and/or toxin production has emerged as an important public health concern. The demand for consuming fresh and low-processed foods free of chemicals and pathogens is increasing. Despite advances in food safety, annually, more than 9 million persons developed illnesses caused by food contamination (Scallan et al., 2011). In Ecuador, the risk of diseases associated with food contaminations is increasing due to incorrect food manipulation, hygiene, and inappropriate storage conditions (Garzon et al., 2017). Although the vendors are continuously capacitated, no improvement on selling sites was made. The food is continuously sold on the street, near parks, transportation terminals, as a common habit. Along with the excessive use of chemicals for preservation, food safety is of concern. To overcome this problem, the application of natural preservation methods might be a suitable solution. Lactic acid bacteria are producing peptides or small proteins namely bacteriocins which could be the next generation of antimicrobials. Thus, their incorporation in food to prevent poisoning or spoilage has been an area of dynamic research in the last decade (Backialakshmi et al., 2015). Previously, we identified two native bacteriocinogenic strains, Lactiplantibacillus plantarum UTNGt2 and L. plantarum UTNCys5-4, producing peptides with a broad spectrum of antibacterial activity against several foodborne pathogens in vitro (Tenea and Pozo, 2019; Tenea and Guana, 2019). Moreover, the addition of those peptide extracts at the exponential phase of growth of the target bacteria (Staphylococcus aureus ATCC1026) results in a decrease of total cell viability with about 3.2-fold (log CFU/ml) order of magnitude at 6 h of incubation, indicating their bactericidal mode of action. In this study, the possible mechanism of action against Staphylococcus aureus was investigated through a series of cell biology analyses such as membrane permeabilization, cell integrity, and structural changes of the target cells. Altogether, the results demonstrated the effectiveness of peptides produced by native lactic acid bacteria to kill Staphylococcus and further investigation is need it to prove the effect in a food matrix.","PeriodicalId":136053,"journal":{"name":"Proceedings of MOL2NET'21, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 7th ed.","volume":"327 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133911155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patentability of hydrogels as biocompatible coatings for medical device biofabrication","authors":"A. Fatimi","doi":"10.3390/mol2net-07-10885","DOIUrl":"https://doi.org/10.3390/mol2net-07-10885","url":null,"abstract":"","PeriodicalId":136053,"journal":{"name":"Proceedings of MOL2NET'21, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 7th ed.","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117237694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and innovation on hydrogels in the world: A scientific overview based on patent applications","authors":"A. Fatimi","doi":"10.3390/mol2net-07-10884","DOIUrl":"https://doi.org/10.3390/mol2net-07-10884","url":null,"abstract":"","PeriodicalId":136053,"journal":{"name":"Proceedings of MOL2NET'21, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 7th ed.","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123609980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}