Inorganics (Basel)最新文献_第8页

Copper(I)/Triphenylphosphine Complexes Containing Naphthoquinone Ligands as Potential Anticancer Agents 含萘醌配体的铜(I)/三苯基膦配合物作为潜在的抗癌剂

Inorganics (Basel) Pub Date : 2023-09-09 DOI: 10.3390/inorganics11090367

Celisnolia M. Leite, João H. Araujo-Neto, Adriana P. M. Guedes, Analu R. Costa, Felipe C. Demidoff, Chaquip D. Netto, Eduardo E. Castellano, Otaciro R. Nascimento, Alzir A. Batista

{"title":"Copper(I)/Triphenylphosphine Complexes Containing Naphthoquinone Ligands as Potential Anticancer Agents","authors":"Celisnolia M. Leite, João H. Araujo-Neto, Adriana P. M. Guedes, Analu R. Costa, Felipe C. Demidoff, Chaquip D. Netto, Eduardo E. Castellano, Otaciro R. Nascimento, Alzir A. Batista","doi":"10.3390/inorganics11090367","DOIUrl":"https://doi.org/10.3390/inorganics11090367","url":null,"abstract":"Four new Cu/PPh3/naphtoquinone complexes were synthesized, characterized (IR, UV/visible, 1D/2D NMR, mass spectrometry, elemental analysis, and X-ray diffraction), and evaluated as anticancer agents. We also investigated the reactive oxygen species (ROS) generation capacity of complex 4, considering the well-established photochemical property of naphthoquinones. Therefore, employing the electron paramagnetic resonance (EPR) “spin trap”, 5,5-dimethyl-1-pyrroline N-oxide (DMPO) technique, we identified the formation of the characteristic •OOH species (hydroperoxyl radical) adduct even before irradiating the solution containing complex 4. As the irradiation progressed, this radical species gradually diminished, primarily giving rise to a novel species known as •DMPO-OH (DMPO + •OH radical). These findings strongly suggest that Cu(I)/PPh3/naphthoquinone complexes can generate ROS, even in the absence of irradiation, potentially intensifying their cytotoxic effect on tumor cells. Interpretation of the in vitro cytotoxicity data of the Cu(I) complexes considered their stability in cell culture medium. All of the complexes were cytotoxic to the lung (A549) and breast tumor cell lines (MDA-MB-231 and MCF-7). However, the higher toxicity for the lung (MRC5) and breast (MCF-10A) non-tumoral cells resulted in a low selectivity index. The morphological analysis of MDA-MB-231 cells treated with the complexes showed that they could cause decreased cell density, loss of cell morphology, and loss of cell adhesion, mainly with concentrations higher than the inhibitory concentration of 50% of cell viability (IC50) values. Similarly, the clonogenic survivance of these cells was affected only with concentrations higher than the IC50 values. An antimigratory effect was observed for complexes 1 and 4, showing around 20–40% of inhibition of wound closure in the wound healing experiments.","PeriodicalId":13580,"journal":{"name":"Inorganics (Basel)","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136192801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Facile Synthesis and Characterization of Novel Nanostructures for the Efficient Disposal of Crystal Violet Dye from Aqueous Media 高效处理水介质中结晶紫染料的新型纳米结构的快速合成和表征

Inorganics (Basel) Pub Date : 2023-08-17 DOI: 10.3390/inorganics11080339

Ehab A. Abdelrahman, Faisal K. Algethami, Huda S. AlSalem, Mona S. Binkadem, Fawaz A. Saad, Gharieb S. El-Sayyad, Nadeem Raza, Khalil ur Rehman

{"title":"Facile Synthesis and Characterization of Novel Nanostructures for the Efficient Disposal of Crystal Violet Dye from Aqueous Media","authors":"Ehab A. Abdelrahman, Faisal K. Algethami, Huda S. AlSalem, Mona S. Binkadem, Fawaz A. Saad, Gharieb S. El-Sayyad, Nadeem Raza, Khalil ur Rehman","doi":"10.3390/inorganics11080339","DOIUrl":"https://doi.org/10.3390/inorganics11080339","url":null,"abstract":"An excessive accumulation of crystal violet dye in the human body results in an accelerated heart rate, tetraplegia, eye irritation, and long-term damage to the transparent mucous membrane that protects the eyeballs. Accordingly, in this paper, sodium manganese silicate/sodium manganese silicate hydroxide hydrate was easily fabricated as a novel type of nanostructures for the successful disposal of crystal violet dye from aqueous solutions. The formed sodium manganese silicate/sodium manganese silicate hydroxide hydrate nanostructures after the hydrothermal treatment of the gel produced from the interaction of Mn(II) ions with Si(IV) ions at 180 °C for 6, 12, 18, and 24 h were abbreviated as MS1, MS2, MS3, and MS4, respectively. The XRD showed that the average crystallite size of the MS1, MS2, MS3, and MS4 samples is 8.38, 7.43, 4.25, and 8.76 nm, respectively. The BET surface area of the MS1, MS2, MS3, and MS4 samples is 41.58, 46.15, 58.25, and 39.69 m2/g, respectively. The MS1, MS2, MS3, and MS4 samples consist of spherical and irregular shapes with average grain sizes of 157.22, 88.06, 43.75, and 107.08 nm, respectively. The best adsorption conditions of the crystal violet dye employing the MS1, MS2, MS3, and MS4 products were achieved at pH = 8, contact time = 140 min, and solution temperature = 298 kelvin. The linear pseudo-2nd-order model as well as the linear Langmuir isotherm better describe the disposal of the crystal violet dye using the MS1, MS2, MS3, and MS4 adsorbents. The studied thermodynamic parameters indicated that the disposal of the crystal violet dye employing the MS1, MS2, MS3, and MS4 adsorbents is spontaneous, exothermic, and chemical. The maximum disposal capacities of the MS1, MS2, MS3, and MS4 adsorbents towards crystal violet dye are 342.47, 362.32, 411.52, and 310.56 mg/g, respectively.","PeriodicalId":13580,"journal":{"name":"Inorganics (Basel)","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136272646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Multifunctional Fluorescent Probe Based on 1,8-Naphthalimide for the Detection of Co2+, F−, and CN− 基于1,8-萘酰亚胺的多功能荧光探针用于检测Co2+， F−和CN−

Inorganics (Basel) Pub Date : 2023-06-22 DOI: 10.3390/inorganics11070265

Ping Li, Xian-Xian Ji, Ming-Yao Xu, Yu-Long Liu, Liu Yang

{"title":"A Multifunctional Fluorescent Probe Based on 1,8-Naphthalimide for the Detection of Co2+, F−, and CN−","authors":"Ping Li, Xian-Xian Ji, Ming-Yao Xu, Yu-Long Liu, Liu Yang","doi":"10.3390/inorganics11070265","DOIUrl":"https://doi.org/10.3390/inorganics11070265","url":null,"abstract":"Cations and anions are indispensable resources for the development of nature and modern industry and agriculture, and exploring more efficient technology to monitor them is urgently needed. A multifunctional fluorescent probe based on 1,8-naphthalimide, N-(2-thiophenhydrazide)acetyl-4-morpholine-1,8-naphthalimide (TMN), was successfully designed and synthesized for the detection of Co2+, F−, and CN−, with N-carboxymethyl-4-morpholine-1,8-naphthalimide and thiophene-2-carbohydrazide as starting materials. TMN displayed superior stability in MeCN with an “on–off” mode towards Co2+, F−, and CN− by the naked eye. The linear response ranges of TMN were 0–3 and 4–19 μM with a detection limit of 0.21 μM for detecting Co2+, 0–5 and 5–22 μM with a detection limit of 0.36 μM for F−, and 0–10 and 10–25 μM with a detection limit of 0.49 μM for CN−. TMN could also recognize Co2+, F−, and CN− in real samples. Finally, the possible sensing mechanisms of TMN for detecting Co2+, F−, and CN− were deeply investigated. These results implied that TMN could be a potential chemosensor for monitoring metal cations and anions sensitively and selectively and could be used in real sample detection.","PeriodicalId":13580,"journal":{"name":"Inorganics (Basel)","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136249571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stem Bark-Mediated Green Synthesis of Silver Nanoparticles from Pyrus pashia: Characterization, Antioxidant, and Antibacterial Properties 茎皮介导的绿色合成pashia纳米银:表征，抗氧化和抗菌性能

Inorganics (Basel) Pub Date : 2023-06-20 DOI: 10.3390/inorganics11060263

Lekha Nath Khanal, Purna Prasad Dhakal, Mani Ram Kandel, Debendra Acharya, Ek Raj Baral, Kisan Chhetri, Surya Kant Kalauni

{"title":"Stem Bark-Mediated Green Synthesis of Silver Nanoparticles from Pyrus pashia: Characterization, Antioxidant, and Antibacterial Properties","authors":"Lekha Nath Khanal, Purna Prasad Dhakal, Mani Ram Kandel, Debendra Acharya, Ek Raj Baral, Kisan Chhetri, Surya Kant Kalauni","doi":"10.3390/inorganics11060263","DOIUrl":"https://doi.org/10.3390/inorganics11060263","url":null,"abstract":"The investigation of using medicinal plants for the production and application of silver nanoparticles (AgNPs) has attracted growing research interest. In this study, AgNPs are synthesized from the stem barks of the Pyrus pashia medicinal plant using a biosynthetic strategy. The reaction conditions were optimized under ambient conditions, including concentration, temperature, time, and pH, and various techniques were employed, such as UV-visible, FTIR, XRD, FESEM, and TEM, to characterize the synthesized AgNPs. The AgNPs produced through this biosynthesis method were found to be spherical and polydispersed, with an average size of 23.92 ± 7.04 nm. The synthesized AgNPs demonstrated an enhanced DPPH free radical scavenging capacity compared to the aqueous extract, with IC50 values of 10.67 ± 0.05 µg/mL and 13.66 ± 0.35 µg/mL, respectively. In the agar well diffusion method, the synthesized AgNPs showed higher antibacterial activity than that of the extract against Escherichia coli (ATCC 25922), Staphylococcus aureus (ATCC 25923), Enterococcus faecalis (ATCC 29212), Salmonella typhi (ATCC 14028), and Shigella sonnei (ATCC 25931). Based on these findings, the study suggests that green synthesized AgNPs from P. pashia could be used for biomedical applications.","PeriodicalId":13580,"journal":{"name":"Inorganics (Basel)","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135236346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbon-Based Sb2(S, Se)3 Solar Cells 碳基Sb2(S, Se)3太阳能电池

Inorganics (Basel) Pub Date : 2023-04-08 DOI: 10.3390/inorganics11040159

Yue Deng, Huicong Liu, Hailiang Wang, Yongfa Song, Weiping Li, Liqun Zhu, Xiangfan Xie, Shuang Xiao, Haining Chen

引用次数: 1

Chemical Tuning and Absorption Properties of Iridium Photosensitizers for Photocatalytic Applications 光催化用铱光敏剂的化学调谐和吸收性能

Inorganics (Basel) Pub Date : 2017-04-12 DOI: 10.3390/INORGANICS5020023

O. Bokareva, Tobias Möhle, A. Neubauer, S. I. Bokarev, S. Lochbrunner, O. Kühn

引用次数: 8

Ammonothermal Synthesis and Crystal Structures of Diamminetriamidodizinc Chloride [Zn2(NH3)2(NH2)3]Cl and Diamminemonoamidozinc Bromide [Zn(NH3)2(NH2)]Br 二胺三胺二氯化锌[Zn2(NH3)2(NH2)3]Cl和二胺一胺二溴化锌[Zn(NH3)2(NH2)]Br的氨热合成及晶体结构

Inorganics (Basel) Pub Date : 2016-12-09 DOI: 10.3390/INORGANICS4040041

Theresia M. M. Richter, Sabine Strobel, N. Alt, E. Schlücker, R. Niewa

引用次数: 5

Water-Soluble Cellulose Derivatives Are Sustainable Additives for Biomimetic Calcium Phosphate Mineralization 水溶性纤维素衍生物是仿生磷酸钙矿化的可持续添加剂

Inorganics (Basel) Pub Date : 2016-10-24 DOI: 10.3390/INORGANICS4040033

A. Taubert, Christian Balischewski, Doreen Hentrich, Thomas Elschner, Sascha Eidner, C. Günter, Karsten Behrens, T. Heinze

{"title":"Water-Soluble Cellulose Derivatives Are Sustainable Additives for Biomimetic Calcium Phosphate Mineralization","authors":"A. Taubert, Christian Balischewski, Doreen Hentrich, Thomas Elschner, Sascha Eidner, C. Günter, Karsten Behrens, T. Heinze","doi":"10.3390/INORGANICS4040033","DOIUrl":"https://doi.org/10.3390/INORGANICS4040033","url":null,"abstract":"The effect of cellulose-based polyelectrolytes on biomimetic calcium phosphate mineralization is described. Three cellulose derivatives, a polyanion, a polycation, and a polyzwitterion were used as additives. Scanning electron microscopy, X-ray diffraction, IR and Raman spectroscopy show that, depending on the composition of the starting solution, hydroxyapatite or brushite precipitates form. Infrared and Raman spectroscopy also show that significant amounts of nitrate ions are incorporated in the precipitates. Energy dispersive X-ray spectroscopy shows that the Ca/P ratio varies throughout the samples and resembles that of other bioinspired calcium phosphate hybrid materials. Elemental analysis shows that the carbon (i.e., polymer) contents reach 10% in some samples, clearly illustrating the formation of a true hybrid material. Overall, the data indicate that a higher polymer concentration in the reaction mixture favors the formation of polymer-enriched materials, while lower polymer concentrations or high precursor concentrations favor the formation of products that are closely related to the control samples precipitated in the absence of polymer. The results thus highlight the potential of (water-soluble) cellulose derivatives for the synthesis and design of bioinspired and bio-based hybrid materials.","PeriodicalId":13580,"journal":{"name":"Inorganics (Basel)","volume":"79 1","pages":"33"},"PeriodicalIF":0.0,"publicationDate":"2016-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84077456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Optical Properties of Heavily Fluorinated Lanthanide Tris β-Diketonate Phosphine Oxide Adducts 重氟化镧系三β-二酮酸膦氧化物加合物的光学性质

Inorganics (Basel) Pub Date : 2016-09-20 DOI: 10.3390/INORGANICS4030027

Adam N. Swinburne, Madeleine H. Langford Paden, T. Chan, S. Randall, F. Ortu, A. Kenwright, L. Natrajan

{"title":"Optical Properties of Heavily Fluorinated Lanthanide Tris β-Diketonate Phosphine Oxide Adducts","authors":"Adam N. Swinburne, Madeleine H. Langford Paden, T. Chan, S. Randall, F. Ortu, A. Kenwright, L. Natrajan","doi":"10.3390/INORGANICS4030027","DOIUrl":"https://doi.org/10.3390/INORGANICS4030027","url":null,"abstract":"The construction of lanthanide(III) chelates that exhibit superior photophysical properties holds great importance in biological and materials science. One strategy to increase the luminescence properties of lanthanide(III) chelates is to hinder competitive non-radiative decay processes through perfluorination of the chelating ligands. Here, the synthesis of two families of heavily fluorinated lanthanide(III) β-diketonate complexes bearing monodentate perfluorinated tris phenyl phosphine oxide ligands have been prepared through a facile one pot reaction [Ln(hfac)3{(ArF)3PO}(H2O)] and [Ln(F7-acac)3{(ArF)3PO}2] (where Ln = Sm3+, Eu3+, Tb3+, Er3+ and Yb3+). Single crystal X-ray diffraction analysis in combination with photophysical studies have been performed to investigate the factors responsible for the differences in the luminescence lifetimes and intrinsic quantum yields of the complexes. Replacement of both bound H2O and C–H oscillators in the ligand backbone has a dramatic effect on the photophysical properties of the complexes, particularly for the near infra-red emitting ion Yb3+, where a five fold increase in luminescence lifetime and quantum yield is observed. The complexes [Sm(hfac)3{(ArF)3PO}(H2O)] (1), [Yb(hfac)3{(ArF)3PO}(H2O)] (5), [Sm(F7-acac)3{(ArF)3PO}2] (6) and [Yb(F7-acac)3{(ArF)3PO}2] (10) exhibit unusually long luminescence lifetimes and attractive intrinsic quantum yields of emission in fluid solution (ΦLn = 3.4% (1); 1.4% (10)) and in the solid state (ΦLn = 8.5% (1); 2.0% (5); 26% (6); 11% (10)), which are amongst the largest values for this class of compounds to date.","PeriodicalId":13580,"journal":{"name":"Inorganics (Basel)","volume":"688 1","pages":"27"},"PeriodicalIF":0.0,"publicationDate":"2016-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74742416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

β,β-Isomer of Open-Wells–Dawson Polyoxometalate Containing a Tetra-Iron(III) Hydroxide Cluster: [{Fe4(H2O)(OH)5}(β,β-Si2W18O66)]9− β，β-含四铁(III)氢氧化物簇的Open-Wells-Dawson多金属氧酸盐异构体:[{Fe4(H2O)(OH)5}(β，β- si2w18o66)]9−

Inorganics (Basel) Pub Date : 2016-05-17 DOI: 10.3390/INORGANICS4020015

Satoshi Matsunaga, Eriko Miyamae, Y. Inoue, K. Nomiya

引用次数: 1