Infection Control & Hospital Epidemiology最新文献

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The impact of a blood-culture diagnostic stewardship intervention on utilization rates and antimicrobial stewardship 血液培养诊断管理干预对使用率和抗菌药物管理的影响
Infection Control & Hospital Epidemiology Pub Date : 2023-12-13 DOI: 10.1017/ice.2023.265
Melinda C. Wang, Kelvin J. Zhou, Sabra L. Shay, James P. Herlihy, Muhammad A. Siddique, Sergio Trevino Castillo, Todd M. Lasco, Miriam Barrett, Mayar Al Mohajer
{"title":"The impact of a blood-culture diagnostic stewardship intervention on utilization rates and antimicrobial stewardship","authors":"Melinda C. Wang, Kelvin J. Zhou, Sabra L. Shay, James P. Herlihy, Muhammad A. Siddique, Sergio Trevino Castillo, Todd M. Lasco, Miriam Barrett, Mayar Al Mohajer","doi":"10.1017/ice.2023.265","DOIUrl":"https://doi.org/10.1017/ice.2023.265","url":null,"abstract":"<p>Blood-culture overutilization is associated with increased cost and excessive antimicrobial use. We implemented an intervention in the adult intensive care unit (ICU), combining education based on the DISTRIBUTE algorithm and restriction to infectious diseases and ICU providers. Our intervention led to reduced blood-culture utilization without affecting safety metrics.</p>","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138580239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of environmental cleaning protocol featuring PX-UV in reducing the incidence of multidrug-resistant gram-negative healthcare-associated infection and colonization in intensive care units in Thailand 采用 PX-UV 技术的环境清洁方案对降低泰国重症监护病房耐多药革兰氏阴性菌医源性感染和定植率的影响
Infection Control & Hospital Epidemiology Pub Date : 2023-12-13 DOI: 10.1017/ice.2023.255
Supavit Vaivoothpinyo, Ornnicha Sathitakorn, Kittiya Jantarathaneewat, David J. Weber, Piyaporn Apisarnthanarak, Sasinuch Rutjanawech, Pichaya Tantiyavarong, Anucha Apisarnthanarak
{"title":"The impact of environmental cleaning protocol featuring PX-UV in reducing the incidence of multidrug-resistant gram-negative healthcare-associated infection and colonization in intensive care units in Thailand","authors":"Supavit Vaivoothpinyo, Ornnicha Sathitakorn, Kittiya Jantarathaneewat, David J. Weber, Piyaporn Apisarnthanarak, Sasinuch Rutjanawech, Pichaya Tantiyavarong, Anucha Apisarnthanarak","doi":"10.1017/ice.2023.255","DOIUrl":"https://doi.org/10.1017/ice.2023.255","url":null,"abstract":"<p>In this quasi-experimental study, implementing PX-UV to the standard environmental cleaning protocol was associated with a reduction in the overall incidence of multidrug-resistant (MDR) gram-negative organisms (<span>P</span> = .01) and MDR <span>Acinetobacter baumannii</span> (<span>P</span> = .001) in intervention intensive care units. However, the intervention did not reduce patient length of stay and 30-day mortality.</p>","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138580118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Persistent colonization of Candida auris among inpatients rescreened as part of a weekly surveillance program 作为每周监测计划的一部分,在住院病人中重新筛查白色念珠菌的持续定植情况
Infection Control & Hospital Epidemiology Pub Date : 2023-12-13 DOI: 10.1017/ice.2023.251
Sebastian P. Arenas, Patrice J. Persad, Samira Patel, Dipen J. Parekh, Tanira B.D. Ferreira, Mirian Farinas, D. Joseph Sexton, Meghan Lyman, Hayley B. Gershengorn, Bhavarth S. Shukla
{"title":"Persistent colonization of Candida auris among inpatients rescreened as part of a weekly surveillance program","authors":"Sebastian P. Arenas, Patrice J. Persad, Samira Patel, Dipen J. Parekh, Tanira B.D. Ferreira, Mirian Farinas, D. Joseph Sexton, Meghan Lyman, Hayley B. Gershengorn, Bhavarth S. Shukla","doi":"10.1017/ice.2023.251","DOIUrl":"https://doi.org/10.1017/ice.2023.251","url":null,"abstract":"<p>We established a surveillance program to evaluate persistence of <span>C. auris</span> colonization among hospitalized patients. Overall, 17 patients (34%) had ≥1 negative result followed by a positive test, and 7 (41%) of these patients had ≥2 consecutive negative tests.</p>","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138579947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of the hospital bed in hospital-onset Clostridioides difficile: A retrospective study with mediation analysis 病床在医院难辨梭状芽孢杆菌感染中的作用:带有中介分析的回顾性研究
Infection Control & Hospital Epidemiology Pub Date : 2023-12-13 DOI: 10.1017/ice.2023.254
Lucy S. Witt, Jessica Howard-Anderson, Radhika Prakash-Asrani, Elizabeth Overton, Jesse T. Jacob
{"title":"The role of the hospital bed in hospital-onset Clostridioides difficile: A retrospective study with mediation analysis","authors":"Lucy S. Witt, Jessica Howard-Anderson, Radhika Prakash-Asrani, Elizabeth Overton, Jesse T. Jacob","doi":"10.1017/ice.2023.254","DOIUrl":"https://doi.org/10.1017/ice.2023.254","url":null,"abstract":"<span>Objective:</span><p>To determine whether residing in a hospital bed that previously held an occupant with <span>Clostridioides difficile</span> increases the risk of hospital-onset <span>C. difficile</span> infection (HO-CDI).</p><span>Methods:</span><p>In this retrospective cohort study, we used a real-time location system to track the movement of hospital beds in 2 academic hospitals from April 2018 to August 2019. We abstracted patient demographics, clinical characteristics, and <span>C. difficile</span> polymerase chain reaction (PCR) results from the medical record. We defined patients as being exposed to a potentially “contaminated” bed or room if, within the preceding 7 days from their HO-CDI diagnosis, they resided in a bed or room respectively, that held an occupant with <span>C. difficile</span> in the previous 90 days. We used multivariable logistic regression to determine whether residing in a contaminated bed was associated with HO-CDI after controlling for time at risk and requiring intensive care. We assessed mediation and interaction from a contaminated hospital room.</p><span>Results:</span><p>Of 25,032 hospital encounters with 18,860 unique patients, we identified 237 cases of HO-CDI. Exposure to a contaminated bed was associated with HO-CDI in unadjusted analyses (odds ratio [OR], 1.8; 95% confidence interval [CI], 1.4–2.31) and adjusted analyses (OR, 1.5; 95% CI, 1.2–2.0). Most of this effect was due to both mediation from and interaction with a contaminated hospital room.</p><span>Conclusions:</span><p>Residing in a hospital bed or room that previously had a patient with <span>C. difficile</span> increases the risk of HO-CDI. Increased attention to cleaning and disinfecting the healthcare environment may reduce hospital transmission of <span>C. difficile</span>.</p>","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138580255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of a coronavirus disease 2019 (COVID-19) vaccine booster with control of a COVID-19 outbreak in a long-term care facility in Switzerland, November to December 2021 2021 年 11 月至 12 月,冠状病毒病 2019(COVID-19)疫苗强化剂与控制瑞士一家长期护理机构的 COVID-19 爆发有关
Infection Control & Hospital Epidemiology Pub Date : 2023-12-13 DOI: 10.1017/ice.2023.240
Thomas W. Leiblein, Annemarie Winistörfer, Kurt Seiler, Rudolf Hauri, Rami Sommerstein
{"title":"Association of a coronavirus disease 2019 (COVID-19) vaccine booster with control of a COVID-19 outbreak in a long-term care facility in Switzerland, November to December 2021","authors":"Thomas W. Leiblein, Annemarie Winistörfer, Kurt Seiler, Rudolf Hauri, Rami Sommerstein","doi":"10.1017/ice.2023.240","DOIUrl":"https://doi.org/10.1017/ice.2023.240","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) outbreaks in long-term care facilities are often correlated with high case fatality rates. We describe the association of administration of an mRNA booster with the control of an outbreak. Our findings highlight the possibility of vaccine booster early in an outbreak as a promising method to mitigate the spread of infection.","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138580013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identifying individual and organizational predictors of accidental exposure to blood (AEB) among hospital healthcare workers: A longitudinal study 确定医院医护人员意外接触血液 (AEB) 的个人和组织预测因素:纵向研究
Infection Control & Hospital Epidemiology Pub Date : 2023-12-13 DOI: 10.1017/ice.2023.248
René Sosata Bun, Karim Aït Bouziad, Oumou Salama Daouda, Katiuska Miliani, Anastasia Eworo, Florence Espinasse, Delphine Seytre, Anne Casetta, Simone Nérome, Laura Temime, Mounia N. Hocine, Pascal Astagneau
{"title":"Identifying individual and organizational predictors of accidental exposure to blood (AEB) among hospital healthcare workers: A longitudinal study","authors":"René Sosata Bun, Karim Aït Bouziad, Oumou Salama Daouda, Katiuska Miliani, Anastasia Eworo, Florence Espinasse, Delphine Seytre, Anne Casetta, Simone Nérome, Laura Temime, Mounia N. Hocine, Pascal Astagneau","doi":"10.1017/ice.2023.248","DOIUrl":"https://doi.org/10.1017/ice.2023.248","url":null,"abstract":"Background: Accidental exposure to blood (AEB) poses a risk of bloodborne infections for healthcare workers (HCWs) during hospital activities. In this study, we identified individual behavioral and organizational predictors of AEB among HCWs. Methods: The study was a prospective, 1-year follow-up cohort study conducted in university hospitals in Paris, France. Data were collected from the Stress at Work and Infectious Risk in Patients and Caregivers (STRIPPS) study. Eligible participants included nurses, nursing assistants, midwives, and physicians from 32 randomly selected wards in 4 hospitals. AEB occurrences were reported at baseline, 4 months, 8 months, and 12 months, and descriptive statistical and multilevel risk-factor analyses were performed. Results: The study included 730 HCWs from 32 wards, predominantly nurses (52.6%), nursing assistants (41.1%), physicians (4.8%), and midwives (1.5%). The incidence rate of AEB remained stable across the 4 visits. The multilevel longitudinal analysis identified several significant predictors of AEB occurrence. Individual-level predictors included younger age, occupation as nurses or midwives, irregular work schedule, rotating shifts, and lack of support from supervisors. The use of external nurses was the most significant ward-level predictor associated with AEB occurrence. Conclusions: AEBs among HCWs are strongly associated with organizational predictors, highlighting the importance of complementing infection control policies with improved staff management and targeted training. This approach can help reduce AEB occurrences and enhance workplace safety for HCWs.","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":"168 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138580127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of computerized clinical decision support system to reduce unnecessary nasal methicillin-resistant Staphylococcus aureus (MRSA) polymerase chain reaction (PCR) testing 评估计算机化临床决策支持系统,以减少不必要的鼻腔耐甲氧西林金黄色葡萄球菌(MRSA)聚合酶链反应(PCR)检测
Infection Control & Hospital Epidemiology Pub Date : 2023-12-12 DOI: 10.1017/ice.2023.256
Duc N. Huynh, Punit J. Shah, Sage B. Greenlee, S. Wesley Long, Muhammad Yasser Alsafadi
{"title":"Evaluation of computerized clinical decision support system to reduce unnecessary nasal methicillin-resistant Staphylococcus aureus (MRSA) polymerase chain reaction (PCR) testing","authors":"Duc N. Huynh, Punit J. Shah, Sage B. Greenlee, S. Wesley Long, Muhammad Yasser Alsafadi","doi":"10.1017/ice.2023.256","DOIUrl":"https://doi.org/10.1017/ice.2023.256","url":null,"abstract":"<p>Our health system implemented a novel clinical decision-support system to reduce unnecessary duplicate nasal methicillin-resistant <span>Staphylococcus aureus</span> (MRSA) polymerase chain reaction (PCR) orders. In an 8-month period, the rate of duplicate MRSA PCR orders within 7 days declined from 4.7% (370 of 7,861) to 1.2% (120 of 9,833).</p>","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138575831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spatiotemporal distribution of community-acquired phenotypic extended-spectrum beta-lactamase Escherichia coli in United States counties, 2010–2019 2010-2019年美国各县社区获得性表型广谱β-内酰胺酶大肠埃希菌的时空分布情况
Infection Control & Hospital Epidemiology Pub Date : 2023-12-11 DOI: 10.1017/ice.2023.266
Matthew W. Smith, Margaret Carrel, Qianyi Shi, Shinya Hasegawa, Gosia Clore, Zhuo Tang, Eli Perencevich, Michihiko Goto
{"title":"Spatiotemporal distribution of community-acquired phenotypic extended-spectrum beta-lactamase Escherichia coli in United States counties, 2010–2019","authors":"Matthew W. Smith, Margaret Carrel, Qianyi Shi, Shinya Hasegawa, Gosia Clore, Zhuo Tang, Eli Perencevich, Michihiko Goto","doi":"10.1017/ice.2023.266","DOIUrl":"https://doi.org/10.1017/ice.2023.266","url":null,"abstract":"<p>Using data from the Veterans’ Health Administration from 2010 to 2019, we examined the distribution and prevalence of community-acquired phenotypic extended-spectrum β-lactamase (ESBL) <span>E. coli</span> in the United States. ESBL prevalence slowly increased during the study period, and cluster analysis showed clustering in both urban and rural locations.</p>","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138568147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence and outcomes of hospital-associated respiratory virus infections by viral species 按病毒种类分列的医院相关呼吸道病毒感染的发病率和结果
Infection Control & Hospital Epidemiology Pub Date : 2023-12-11 DOI: 10.1017/ice.2023.263
Joshua G. Petrie, Riley Moore, Adam S. Lauring, Keith S. Kaye
{"title":"Incidence and outcomes of hospital-associated respiratory virus infections by viral species","authors":"Joshua G. Petrie, Riley Moore, Adam S. Lauring, Keith S. Kaye","doi":"10.1017/ice.2023.263","DOIUrl":"https://doi.org/10.1017/ice.2023.263","url":null,"abstract":"<span>Background:</span><p>Although the incidence of hospital-associated respiratory virus infection (HARVI) is well recognized, the risk factors for infection and impact on patient outcomes are not well characterized.</p><span>Methods:</span><p>We identified a cohort of all inpatient admissions ≥24 hours duration at a single academic medical center from 2017 to 2020. HARVI were defined as respiratory virus detected in a test ordered after the 95th percentile of the virus-specific incubation period. Risk factors for HARVI were assessed using Cox proportional hazards models of the competing outcomes of HARVI and discharge. The associations between time-varying HARVI status and the rates of ICU admission, discharge, and in-hospital death were estimated using Cox-proportional hazards models in a competing risk framework.</p><span>Results:</span><p>HARVI incidences were 8.8 and 3.0 per 10,000 admission days for pediatric and adult patients, respectively. For adults, congestive heart failure, renal disease, and cancer increased HARVI risk independent of their associations with length of stay. HARVI risk was also elevated for patients admitted in September–June relative to July admissions. For pediatric patients, cardiovascular and respiratory conditions, cancer, medical device dependence, and admission in December increased HARVI risk. Lengths of stay were longer for adults with HARVI compared to those without, and hospital-associated influenza A was associated with increased risk of death. Rates of ICU admission were increased in the 5 days after HARVI identification for adult and pediatric patients. HARVI was not associated with length of stay or death among pediatric patients.</p><span>Conclusions:</span><p>HARVI is associated chronic health conditions and increases morbidity and mortality.</p>","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138568141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of an antibiotic stewardship initiative on urgent-care respiratory prescribing across patient race, ethnicity, and language 抗生素管理倡议对不同种族、族裔和语言的急诊呼吸科处方的影响
Infection Control & Hospital Epidemiology Pub Date : 2023-12-11 DOI: 10.1017/ice.2023.258
Allan M. Seibert, Adam L. Hersh, Payal K. Patel, Lauri A. Hicks, Nora Fino, Valoree Stanfield, Edward A. Stenehjem
{"title":"Impact of an antibiotic stewardship initiative on urgent-care respiratory prescribing across patient race, ethnicity, and language","authors":"Allan M. Seibert, Adam L. Hersh, Payal K. Patel, Lauri A. Hicks, Nora Fino, Valoree Stanfield, Edward A. Stenehjem","doi":"10.1017/ice.2023.258","DOIUrl":"https://doi.org/10.1017/ice.2023.258","url":null,"abstract":"<p>We conducted a post hoc analysis of an antibiotic stewardship intervention implemented across our health system’s urgent-care network to determine whether there was a differential impact among patient groups. Respiratory urgent-care antibiotic prescribing decreased for all racial, ethnic, and preferred language groups, but disparities in antibiotic prescribing persisted.</p>","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138568142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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