Infection Control & Hospital Epidemiology最新文献

{"title":"Healthcare personnel opinions regarding the feasibility of a risk-tailored approach to contact precautions for methicillin-resistant Staphylococcus aureus in the acute care setting","authors":"Lyndsay M. O’Hara, Anthony D. Harris, David P. Calfee, Graham M. Snyder, James Cottam, Nathan N. O’Hara, Elise M. Martin","doi":"10.1017/ice.2024.54","DOIUrl":"https://doi.org/10.1017/ice.2024.54","url":null,"abstract":"“All or none” approaches to the use of contact precautions for methicillin-resistant <jats:italic>Staphylococcus aureus</jats:italic> (MRSA) both fail to recognize that transmission risk varies. This qualitative study assessed healthcare personnel perspectives regarding the feasibility of a risk-tailored approach to use contact precautions for MRSA more strategically in the acute care setting.","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140635174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A multi-center validation of the electronic health record admission source and discharge location fields against the clinical notes for identifying inpatients with long-term care facility exposure","authors":"Katherine E. Goodman, Monica Taneja, Laurence S. Magder, Eili Y. Klein, Mark Sutherland, Scott Sorongon, Pranita D. Tamma, Philip Resnik, Anthony D. Harris","doi":"10.1017/ice.2024.37","DOIUrl":"https://doi.org/10.1017/ice.2024.37","url":null,"abstract":"<p>Identifying long-term care facility (LTCF)-exposed inpatients is important for infection control research and practice, but ascertaining LTCF exposure is challenging. Across a large validation study, electronic health record data fields identified 76% of LTCF-exposed patients compared to manual chart review.</p>","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140609893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surveillance of carbapenem-resistant Klebsiella pneumoniae and Escherichia coli in perianal swab samples","authors":"Gül Çalışkan, Hale Eren, Funda Aslan, Nergis Tezgeç, Habibe İmer, Esma Souleiman, Ülkü Tüzemen, Uğur Önal, Esra Kazak, Yasemin Heper, Emel Yılmaz, Cüneyt Özakın, Halis Akalın","doi":"10.1017/ice.2024.60","DOIUrl":"https://doi.org/10.1017/ice.2024.60","url":null,"abstract":"Our study aimed to detect carbapenem-resistant <jats:italic>Klebsiella pneumoniae</jats:italic> (CRKP) and/or carbapenem-resistant <jats:italic>Escherichia coli</jats:italic> in perianal swab samples, exploring their link to bloodstream infections (BSIs) in a tertiary-care university hospital. CRKP-related BSIs ranged from 3.7% to 9.58%, emphasizing the need to understand local risk factors for effective infection control.","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140583422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative epidemiology of hospital-onset bloodstream infections (HOBSIs) and central line-associated bloodstream infections (CLABSIs) across a three-hospital health system","authors":"Jay Krishnan, Erin B. Gettler, Melissa Campbell, Ibukunoluwa C. Kalu, Jessica Seidelman, Becky Smith, Sarah Lewis","doi":"10.1017/ice.2024.38","DOIUrl":"https://doi.org/10.1017/ice.2024.38","url":null,"abstract":"<span>Objective:</span><p>To evaluate the comparative epidemiology of hospital-onset bloodstream infection (HOBSI) and central line-associated bloodstream infection (CLABSI)</p><span>Design and Setting:</span><p>Retrospective observational study of HOBSI and CLABSI across a three-hospital healthcare system from 01/01/2017 to 12/31/2021</p><span>Methods:</span><p>HOBSIs were identified as any non-commensal positive blood culture event on or after hospital day 3. CLABSIs were identified based on National Healthcare Safety Network (NHSN) criteria. We performed a time-series analysis to assess comparative temporal trends among HOBSI and CLABSI incidence. Using univariable and multivariable regression analyses, we compared demographics, risk factors, and outcomes between non-CLABSI HOBSI and CLABSI, as HOBSI and CLABSI are not exclusive entities.</p><span>Results:</span><p>HOBSI incidence increased over the study period (IRR 1.006 HOBSI/1,000 patient days; 95% CI 1.001–1.012; <span>P</span> = .03), while no change in CLABSI incidence was observed (IRR .997 CLABSIs/1,000 central line days, 95% CI .992–1.002, <span>P</span> = .22). Differing demographic, microbiologic, and risk factor profiles were observed between CLABSIs and non-CLABSI HOBSIs. Multivariable analysis found lower odds of mortality among patients with CLABSIs when adjusted for covariates that approximate severity of illness (OR .27; 95% CI .11–.64; <span>P</span> &lt; .01).</p><span>Conclusions:</span><p>HOBSI incidence increased over the study period without a concurrent increase in CLABSI in our study population. Furthermore, risk factor and outcome profiles varied between CLABSI and non-CLABSI HOBSI, which suggest that these metrics differ in important ways worth considering if HOBSI is adopted as a quality metric.</p>","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140169875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Control of SARS-CoV-2 infection in skilled nursing facilities in Detroit, Michigan: a model for emerging infectious diseases","authors":"Seema Joshi, Samia Arshad, Abigail Lindsay, Jessica Heinonen, Helina Misikir, John Zervos, Tyler Prentiss, Jelena Verkler, Mariia Numi, Bonnie Czander, Randy E. David, Michael Mossing, Paul E. Kilgore, Najibah Rehman, Marcus Zervos","doi":"10.1017/ice.2024.35","DOIUrl":"https://doi.org/10.1017/ice.2024.35","url":null,"abstract":"<p>An infection prevention bundle that consisted of the development of a response team, public–academic partnership, daily assessment, regular testing, isolation, and environmental controls was implemented in 26 skilled nursing facilities in Detroit, Michigan (March 2020–April 2021). This intervention was associated with sustained control of severe acute respiratory coronavirus virus 2 infection among residents and staff.</p>","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140169355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modeling relaxed policies for discontinuation of methicillin-resistant Staphylococcus aureus contact precautions","authors":"Jiaming Cui, Jack Heavey, Leo Lin, Eili Y. Klein, Gregory R. Madden, Costi D. Sifri, Bryan Lewis, Anil K. Vullikanti, B. Aditya Prakash","doi":"10.1017/ice.2024.23","DOIUrl":"https://doi.org/10.1017/ice.2024.23","url":null,"abstract":"<span>Objective:</span><p>To evaluate the economic costs of reducing the University of Virginia Hospital’s present “3-negative” policy, which continues methicillin-resistant <span>Staphylococcus aureus</span> (MRSA) contact precautions until patients receive 3 consecutive negative test results, to either 2 or 1 negative.</p><span>Design:</span><p>Cost-effective analysis.</p><span>Settings:</span><p>The University of Virginia Hospital.</p><span>Patients:</span><p>The study included data from 41,216 patients from 2015 to 2019.</p><span>Methods:</span><p>We developed a model for MRSA transmission in the University of Virginia Hospital, accounting for both environmental contamination and interactions between patients and providers, which were derived from electronic health record (EHR) data. The model was fit to MRSA incidence over the study period under the current 3-negative clearance policy. A counterfactual simulation was used to estimate outcomes and costs for 2- and 1-negative policies compared with the current 3-negative policy.</p><span>Results:</span><p>Our findings suggest that 2-negative and 1-negative policies would have led to 6 (95% CI, −30 to 44; <span>P</span> &lt; .001) and 17 (95% CI, −23 to 59; −10.1% to 25.8%; <span>P</span> &lt; .001) more MRSA cases, respectively, at the hospital over the study period. Overall, the 1-negative policy has statistically significantly lower costs ($628,452; 95% CI, $513,592–$752,148) annually (<span>P</span> &lt; .001) in US dollars, inflation-adjusted for 2023) than the 2-negative policy ($687,946; 95% CI, $562,522–$812,662) and 3-negative ($702,823; 95% CI, $577,277–$846,605).</p><span>Conclusions:</span><p>A single negative MRSA nares PCR test may provide sufficient evidence to discontinue MRSA contact precautions, and it may be the most cost-effective option.</p>","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139968247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of an intervention to reduce dispersal from wastewater drain sites on carbapenem-resistant Pseudomonas aeruginosa colonization and bloodstream infection on a hematopoietic cell transplant and hematologic malignancy unit","authors":"Lauren Fontana, Morgan Hakki, Egon A. Ozer, Amy Laird, Lynne Strasfeld","doi":"10.1017/ice.2023.288","DOIUrl":"https://doi.org/10.1017/ice.2023.288","url":null,"abstract":"<span>Objective:</span><p>To evaluate the impact of an intervention to limit dispersal from wastewater drain (WWD) sites on meropenem-nonsusceptible <span>Pseudomonas aeruginosa</span> patient and environmental colonization and bloodstream infection (BSI) on a hematopoietic cell transplant (HCT) and hematologic malignancy (HM) unit.</p><span>Design:</span><p>This quasi-experimental study included pre/postintervention point-prevalence surveys in July 2019 and June 2020, respectively. The retrospective cohort included HCT/HM patients with <span>P. aeruginosa</span> BSI between 2012 and 2022.</p><span>Setting:</span><p>Adult HCT/HM unit at an academic center.</p><span>Participants:</span><p>This study included consenting HCT/HM patients on the unit at the time of the point-prevalence surveys. HCT/HM patients with <span>P. aeruginosa</span> BSI between 2012 and 2022.</p><span>Methods:</span><p>A quality improvement intervention targeting WWD sites was conceived and implemented on a HCT/HM unit. Pre and postintervention colonization samples were obtained from patients and environmental sites, cultivated on selective media, then characterized by susceptibility testing. Whole-genome sequencing and phylogenetic analysis were performed on select isolates. The impact of the intervention on colonization and BSI was evaluated, as was relatedness among isolates.</p><span>Results:</span><p>Although colonization of WWD sites with meropenem-nonsusceptible <span>P. aeruginosa</span> was widespread before and after this intervention, we observed a substantial decline in patient colonization (prevalence rate ratio, 0.35; 95% confidence interval [CI], 0.04–3.12) and BSI (incidence rate ratio, 0.67; 95% CI, 0.31–1.42) after the intervention. Among 3 predominant sequence types (ST-111, ST-446, and ST-308), there was striking genetic conservation within groups and among environmental colonization, patient colonization, and BSI isolates.</p><span>Conclusions:</span><p>An intervention targeting WWD sites on a HCT/HM unit had a meaningful impact on meropenem-nonsusceptible <span>P. aeruginosa</span> patient colonization and BSI.</p>","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139926715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of minimally invasive surgical approaches on surgical-site infections","authors":"Stephanie F. Sweitzer, Emily E. Sickbert-Bennett, Jessica Seidelman, Deverick J. Anderson, Moe R. Lim, David J. Weber","doi":"10.1017/ice.2023.277","DOIUrl":"https://doi.org/10.1017/ice.2023.277","url":null,"abstract":"<p>We performed a literature review to describe the risk of surgical-site infection (SSI) in minimally invasive surgery (MIS) compared to standard open surgery. Most studies reported decreased SSI rates among patients undergoing MIS compared to open procedures. However, many were observational studies and may have been affected by selection bias. MIS is associated with reduced risk of surgical-site infection compared to standard open surgery and should be considered when feasible.</p>","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139083916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ICE volume 45 issue 1 Cover and Front matter","authors":"D. Yokoe, Patricia Jackson, David C. Classen, C. Rhee, Ray Dantes, A. Benin, Julie Tsu-Yu, Tsu-Yu Wu, Erica S. Shenoy, Evan P. Carey, Gil Alterovitz, Michael J. Kim, W. Branch-Elliman, Carissa M. Windish, Priya Nori, Kimberly C. Dukes, Heather R S Reisinger, Marin L. Schweizer, M. Ward, Laura Chapin, T. Ryken, T. Perl, L. Herwaldt, Mary Fornek, Subhan Ata, Edwin Jimenez, M. Abdallah, S. Sunny, Jennifer Lee, Briana Episcopia, Valery Roudnitsky, John Quale, Jérémy Picard, B. Nkoumazok, Isabelle Arnaud, D. Verjat-trannoy, Pascal Astagneau, Kelsey M. Fillman, Jonathan H. Ryder, Daniel M. Brailita, Mark E. Rupp, R. Cavalieri, Paul D. Fey, Elizabeth R. Lyden, Richard J Hankins, Karen M. Jones, Sarah L. Krein, J. Mantey, M. Harrod, L. Mody, Gang Ye Kalvin C. Yu, Jonathan R. Edwards, Vikas Gupta, ChinEn Ai, Kristina Betz, Andrew S. Crone, Lorinda M. Wright, Adam K Cheknis, Stuart Johnson, S. Pacheco, Andrew M. Skinner, Hao-Hsin Wu, Chiu-Hsia Su, Li-Jung Chien, S. Tseng, Shan-Chwen Chang, L. S. Ocampo, Eric Hall, ","doi":"10.1017/ice.2023.290","DOIUrl":"https://doi.org/10.1017/ice.2023.290","url":null,"abstract":"","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139457855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ICE volume 45 issue 1 Cover and Back matter","authors":"","doi":"10.1017/ice.2023.291","DOIUrl":"https://doi.org/10.1017/ice.2023.291","url":null,"abstract":"","PeriodicalId":13558,"journal":{"name":"Infection Control & Hospital Epidemiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139457778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}