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Intrathyroidal thymic carcinoma not so indolent a neoplasm? 甲状旁腺内胸腺癌并非是一种轻度肿瘤？
IF 0.8 4区 医学
Indian Journal of Pathology and Microbiology Pub Date : 2024-07-01 Epub Date: 2023-06-21 DOI: 10.4103/ijpm.ijpm_232_23
K R Anila, Iswarya S Nair, Lekha M Nair, Shaji Thomas
{"title":"Intrathyroidal thymic carcinoma not so indolent a neoplasm?","authors":"K R Anila, Iswarya S Nair, Lekha M Nair, Shaji Thomas","doi":"10.4103/ijpm.ijpm_232_23","DOIUrl":"10.4103/ijpm.ijpm_232_23","url":null,"abstract":"<p><strong>Abstract: </strong>Intrathyroidal thymic carcinoma (ITC) is a very rare malignant epithelial tumor of the thyroid gland with thymic epithelial differentiation. Here, we are reporting the case of an eighty-year-old man who at presentation had extrathyroidal spread to the larynx and metastasis to regional lymph nodes. Though the tumor had a relatively low-grade morphology, there were areas of high mitotic activity with areas of necrosis. The classically described ivory-white gross appearance of the tumor, histomorphology of thick bands dividing the tumor into lobules, squamous cell differentiation, tight whorls of cells resembling Hassall's corpuscle, and areas showing dense lymphocytic infiltration, together with an immunoprofile of CD5, Ckit, Tumor protein 63 (p63), and B-cell lymphoma 2 gene (bcl2) positivity, helped in diagnosing this rare entity. Though classically ITC is said to have a good prognosis, cases with spread to adjacent organs and lymph node metastasis may not have an indolent course.</p>","PeriodicalId":13488,"journal":{"name":"Indian Journal of Pathology and Microbiology","volume":"1 1","pages":"628-630"},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70762327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case report of a rare fungal infection Kodamaea ohmeri in COVID-19 patient in North Malaysian hospital. 北马来西亚医院 COVID-19 患者罕见真菌感染 Kodamaea ohmeri 的病例报告。
IF 0.8 4区 医学
Indian Journal of Pathology and Microbiology Pub Date : 2024-07-01 Epub Date: 2023-07-26 DOI: 10.4103/ijpm.ijpm_972_22
Humaira Farooq, Gokul Shankar Sabesan, Tahmina Monowar, Suresh V Chinni, Noor H Zainol
{"title":"Case report of a rare fungal infection Kodamaea ohmeri in COVID-19 patient in North Malaysian hospital.","authors":"Humaira Farooq, Gokul Shankar Sabesan, Tahmina Monowar, Suresh V Chinni, Noor H Zainol","doi":"10.4103/ijpm.ijpm_972_22","DOIUrl":"10.4103/ijpm.ijpm_972_22","url":null,"abstract":"<p><strong>Abstract: </strong>Kodamaea ohmeri is a rare opportunistic pathogen belonging to Saccharomycetes family. This yeast was also formerly known as Yamadazyma ohmeri or Pichia ohmeri . This opportunistic pathogen causes illness that typically affects people with impaired immune system. In this report, we discuss a fatal case involving a woman in her late 30s who was admitted to the hospital on the sixth day of her sickness after being given a COVID-19 Category 5A diagnosis. For COVID-19, she received subcutaneous heparin, cefuroxime, and intravenous corticosteroids. She was diagnosed with secondary bacterial and fungal infections in the ICU. Multiple antibiotics and antifungal were given to treat bacterial and fungal infections. An unusual fungus, Kodamaea ohmeri , was isolated from the clinical sample. On day 36, she succumbed to her infection in the ICU. The cause of death was multidrug-resistant sepsis with multiple organ failures due to COVID-19 infection, worsened by an embolism and trachea damage during a tracheostomy. To effectively manage K. ohmeri , clinicians and microbiologists must identify and be aware of this emerging human opportunistic pathogen, which can co-infect debilitated patients such as COVID-19 patients, for effective management.</p>","PeriodicalId":13488,"journal":{"name":"Indian Journal of Pathology and Microbiology","volume":"1 1","pages":"654-657"},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70763897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extensive intramural calcification in neonatal ileal atresia: An unusual finding. 新生儿回肠闭锁的广泛壁内钙化：不寻常的发现
IF 0.8 4区 医学
Indian Journal of Pathology and Microbiology Pub Date : 2024-07-01 Epub Date: 2023-07-26 DOI: 10.4103/ijpm.ijpm_890_22
Pallavi Prasad, Paturu Radha, Basant Kumar, Pujana Kanneganti
{"title":"Extensive intramural calcification in neonatal ileal atresia: An unusual finding.","authors":"Pallavi Prasad, Paturu Radha, Basant Kumar, Pujana Kanneganti","doi":"10.4103/ijpm.ijpm_890_22","DOIUrl":"10.4103/ijpm.ijpm_890_22","url":null,"abstract":"","PeriodicalId":13488,"journal":{"name":"Indian Journal of Pathology and Microbiology","volume":"1 1","pages":"703-705"},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70763435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multifocal intraosseous pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma: A rare presentation of an uncommon tumor. 多灶性骨内假肌源性（上皮样肉瘤样）血管内皮瘤：一种不常见肿瘤的罕见表现。
IF 0.8 4区 医学
Indian Journal of Pathology and Microbiology Pub Date : 2024-07-01 Epub Date: 2023-07-26 DOI: 10.4103/ijpm.ijpm_995_22
Vishwapriya M Godkhindi, Vidya Monappa, Sharada Mailankody, Umesh Velu, Shuiab M V Mohammed, Aisharya Banerjee
{"title":"Multifocal intraosseous pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma: A rare presentation of an uncommon tumor.","authors":"Vishwapriya M Godkhindi, Vidya Monappa, Sharada Mailankody, Umesh Velu, Shuiab M V Mohammed, Aisharya Banerjee","doi":"10.4103/ijpm.ijpm_995_22","DOIUrl":"10.4103/ijpm.ijpm_995_22","url":null,"abstract":"<p><strong>Abstract: </strong>Pseudomyogenic hemangioendothelioma (PHE) is an uncommon mesenchymal neoplasm of intermediate malignant potential showing endothelial differentiation. Around 20 cases of primary osseous PHE have been reported to date. A 16-year-old boy presented with complaints of pain in his right leg. Imaging revealed multifocal intramedullary and cortical-based lytic lesions involving long and small bones. Microscopic examination revealed plump, spindled cells arranged in fascicles and admixed \"epithelioid\" and \"rhabdoid\" cells sans vasoformative areas. By immunohistochemistry, the lesional cells were reactive for AE1/AE3, CD31, Erg, Fli1, and SMA, while immunonegative for CD34, myogenin, and S100. Nuclear expression of the INI1/SMARCB1 protein was retained. PHE is a rare entity, more so as a primary osseous lesion; therefore, awareness of the presence of this entity in the bone is the key to making a diagnosis. We discuss its clinicopathological features, differential diagnosis, and an attempt a short review of the literature.</p>","PeriodicalId":13488,"journal":{"name":"Indian Journal of Pathology and Microbiology","volume":"1 1","pages":"661-664"},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70763557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-mortem detection of a calcifying fibrous pseudotumor at a rare site-A case report. 尸检发现罕见部位的钙化纤维性假瘤--病例报告。
IF 0.8 4区 医学
Indian Journal of Pathology and Microbiology Pub Date : 2024-07-01 Epub Date: 2023-07-26 DOI: 10.4103/ijpm.ijpm_377_22
Jhansi L Mylapalli, Hemlata Jangir, Meenakshi Sharma, Vidhu Prabhakar, Piyush R Sandhu, Arulselvi Subramanian, Adarsh Barwad, Sanjeev Lalwani
{"title":"Post-mortem detection of a calcifying fibrous pseudotumor at a rare site-A case report.","authors":"Jhansi L Mylapalli, Hemlata Jangir, Meenakshi Sharma, Vidhu Prabhakar, Piyush R Sandhu, Arulselvi Subramanian, Adarsh Barwad, Sanjeev Lalwani","doi":"10.4103/ijpm.ijpm_377_22","DOIUrl":"10.4103/ijpm.ijpm_377_22","url":null,"abstract":"<p><strong>Abstract: </strong>We report the case of a 48 year old man brought-in-dead to the trauma unit following an alleged accidental fall from a multi-storied building. Autopsy findings were consistent with traumatic injuries to the head, chest and spine. Incidentally, a bit of the diaphragm with a pearly white lobulated mass over the pleural surface was observed. Histopathological examination detected a calcifying fibrous pseudotumour (CFPT), confirmed by positive immunostaining for cluster of differentiation protein-34 (CD34) and vimentin (focally). CFPTs are slow-growing pseudotumours that are clinically benign with extremely low rate of recurrence and this might just be the first reported case of CFPT on the diaphragm. This shall further aid clinicians to diagnose these rare yet significant soft tissue tumors in uncommon sites.</p>","PeriodicalId":13488,"journal":{"name":"Indian Journal of Pathology and Microbiology","volume":"1 1","pages":"669-671"},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70761999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An ectomesenchymal chondromyxoid tumor: A case report of a rare tumor in the rare age group and at a rare site. 外胚层软骨样肿瘤：罕见年龄组和罕见部位的罕见肿瘤病例报告。
IF 0.8 4区 医学
Indian Journal of Pathology and Microbiology Pub Date : 2024-07-01 Epub Date: 2023-07-26 DOI: 10.4103/ijpm.ijpm_926_22
Akshi Raj, Madhuri Singh, Shirish S Chandanwale, Charusheela R Gore, Mayur Ambekar
{"title":"An ectomesenchymal chondromyxoid tumor: A case report of a rare tumor in the rare age group and at a rare site.","authors":"Akshi Raj, Madhuri Singh, Shirish S Chandanwale, Charusheela R Gore, Mayur Ambekar","doi":"10.4103/ijpm.ijpm_926_22","DOIUrl":"10.4103/ijpm.ijpm_926_22","url":null,"abstract":"","PeriodicalId":13488,"journal":{"name":"Indian Journal of Pathology and Microbiology","volume":"1 1","pages":"706-707"},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70763711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mesenchymal chondrosarcoma with rhabdomyoblastic differentiation: A malignant round cell tumor with enigmatic immunohistochemical profile. 横纹肌母细胞分化的间质软骨肉瘤：一种具有神秘免疫组化特征的恶性圆形细胞瘤。
IF 0.8 4区 医学
Indian Journal of Pathology and Microbiology Pub Date : 2024-07-01 Epub Date: 2023-07-26 DOI: 10.4103/ijpm.ijpm_299_22
Diksha Karki, Sunil Pasricha, Anila Sharma, Payal Malhotra, Ankush Jajodia, Anurag Mehta
{"title":"Mesenchymal chondrosarcoma with rhabdomyoblastic differentiation: A malignant round cell tumor with enigmatic immunohistochemical profile.","authors":"Diksha Karki, Sunil Pasricha, Anila Sharma, Payal Malhotra, Ankush Jajodia, Anurag Mehta","doi":"10.4103/ijpm.ijpm_299_22","DOIUrl":"10.4103/ijpm.ijpm_299_22","url":null,"abstract":"","PeriodicalId":13488,"journal":{"name":"Indian Journal of Pathology and Microbiology","volume":"1 1","pages":"708-710"},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70762162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute appendicitis the first sign of appendiceal metastasis of an inoperable carcinoma of stomach-A case report and a review of literature. 急性阑尾炎是无法手术的胃癌阑尾转移的首发症状--病例报告和文献综述。
IF 0.8 4区 医学
Indian Journal of Pathology and Microbiology Pub Date : 2024-07-01 Epub Date: 2023-07-26 DOI: 10.4103/ijpm.ijpm_816_22
Dhaneshwar N Lanjewar, Pooja H Katharotiya, Palak M Lakhani, Mansi M Thacker
{"title":"Acute appendicitis the first sign of appendiceal metastasis of an inoperable carcinoma of stomach-A case report and a review of literature.","authors":"Dhaneshwar N Lanjewar, Pooja H Katharotiya, Palak M Lakhani, Mansi M Thacker","doi":"10.4103/ijpm.ijpm_816_22","DOIUrl":"10.4103/ijpm.ijpm_816_22","url":null,"abstract":"<p><strong>Abstract: </strong>Appendicitis is the most common cause of the acute abdomen and usually occurs because of the fecalith in adults and lymphoid hyperplasia in childhood. Gastric cancer metastasis to the appendix is a rare condition that might be present with symptoms of acute appendicitis. The English literature describes only thirteen cases of gastric carcinoma metastasizing to the appendix and presenting as acute appendicitis. In this report, we describe the first case of metastatic signet ring cell carcinoma of appendix presenting with clinical features of acute appendicitis.</p>","PeriodicalId":13488,"journal":{"name":"Indian Journal of Pathology and Microbiology","volume":"1 1","pages":"648-650"},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70762994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endocardial fibroelastosis causing sudden death in an infant: Autopsy case report of an unusual lesion. 导致婴儿猝死的心内膜纤维细胞增生症：不寻常病变的尸检病例报告。
IF 0.8 4区 医学
Indian Journal of Pathology and Microbiology Pub Date : 2024-07-01 Epub Date: 2023-07-26 DOI: 10.4103/ijpm.ijpm_863_22
Bhavya P Mohan, V K Rajendraprasad, K S Parthasarathy, Togy Thomas Zacharia
{"title":"Endocardial fibroelastosis causing sudden death in an infant: Autopsy case report of an unusual lesion.","authors":"Bhavya P Mohan, V K Rajendraprasad, K S Parthasarathy, Togy Thomas Zacharia","doi":"10.4103/ijpm.ijpm_863_22","DOIUrl":"10.4103/ijpm.ijpm_863_22","url":null,"abstract":"<p><strong>Abstract: </strong>Endocardial fibroelastosis is characterized by proliferation of both elastic and collagenous fibers within the endocardium, causing diffuse or localized thickening. A four-and-a-half-month-old baby was admitted to a local hospital, with a history of seizures for one day. Baby developed features of heart failure and died within one week after admission. At the post-mortem examination, heart was found to be enlarged with dilated ventricles. The endocardium of left ventricle was markedly thickened with a whitish appearance. Histopathology showed a thick layer of collagenous fibrous tissue in the endocardium, which was confirmed by Masson trichrome stain. The cause of death was offered as dilated cardiomyopathy due to endocardial fibroelastosis. The underlying mechanisms of myocardial fibrosis remain unclear. It is hypothesized that genetic, infectious, inflammatory, and nutritional processes are involved in this condition. This case highlights the importance of gross specimen examination and special staining methods to support histopathology after postmortem examination, for ascertaining the cause of death.</p>","PeriodicalId":13488,"journal":{"name":"Indian Journal of Pathology and Microbiology","volume":"1 1","pages":"665-668"},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70763140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Burnt out testicular tumor - A case report. 烧毁的睾丸肿瘤--病例报告。
IF 0.8 4区 医学
Indian Journal of Pathology and Microbiology Pub Date : 2024-07-01 Epub Date: 2023-07-26 DOI: 10.4103/ijpm.ijpm_125_22
Shri Lakshmi Surapaneni, Ramakoteswar R Nutakki, Vandana Gangadharan, Rupa K Gara
{"title":"Burnt out testicular tumor - A case report.","authors":"Shri Lakshmi Surapaneni, Ramakoteswar R Nutakki, Vandana Gangadharan, Rupa K Gara","doi":"10.4103/ijpm.ijpm_125_22","DOIUrl":"10.4103/ijpm.ijpm_125_22","url":null,"abstract":"<p><strong>Abstract: </strong>Spontaneous regression of testicular tumors known as burnt-out tumor of testis is a rare entity and is seen in about 5% of testicular germ cell tumors. It is described as a spontaneously, completely, or partially regressed testicular tumor with or without metastasis in the absence of any treatment. This entity is now included in the 2016 classification of testicular tumors. This is probably only the second case presented in India. High degree of awareness of this entity by the pathologist, clinician, and radiologist is necessary for proper management and survival of the patient.</p>","PeriodicalId":13488,"journal":{"name":"Indian Journal of Pathology and Microbiology","volume":"1 1","pages":"645-647"},"PeriodicalIF":0.8,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70762255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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