Indonesian Journal of Obstetrics and Gynecology最新文献

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Assosiation between Serum Cortisol Levels and Anxiety levels In Elective and Emergency Cesarean Section 选择性剖宫产和急诊剖宫产患者血清皮质醇水平与焦虑水平的关系
Indonesian Journal of Obstetrics and Gynecology Pub Date : 2022-10-30 DOI: 10.32771/inajog.v10i4.1624
Nadia O. S. Nurdin, John J. E. Wantania, Ronny A. A. Mewengkang
{"title":"Assosiation between Serum Cortisol Levels and Anxiety levels In Elective and Emergency Cesarean Section","authors":"Nadia O. S. Nurdin, John J. E. Wantania, Ronny A. A. Mewengkang","doi":"10.32771/inajog.v10i4.1624","DOIUrl":"https://doi.org/10.32771/inajog.v10i4.1624","url":null,"abstract":"Objective: To detect anxiety before elective and emergency cesarean section. \u0000Methods: This study was a cross-sectional study. The number of research samples was 42 samples consisting of 21 pregnant patients with an elective cesarean section plan and 21 pregnant patients with an emergency cesarean section at Prof. RSUP. Dr. R. D. Kandou Hospital Manado and Network Hospital in Manado from March 2021 to June 2021. Anxiety was assessed by examining serum cortisol and anxiety levels according to the Hamilton questionnaire (HAM-A). The data were then analyzed using SPSS version 23.0 software. \u0000Results: Cortisol levels were higher in emergency cesarean section (mean 21.590±11.6392) compared to elective cesarean section (mean 10.586±4.9501). Anxiety levels according to HAM-A scores were higher in emergency cesarean section (mean 15.33±7.722) compared to elective cesarean section (mean 7.19±3.614). \u0000Conclusion: There was a significant positive correlation between cortisol levels and anxiety levels based on HAM-A scores. \u0000Keywords: cesarean section , cortisol, HAM-A score. anxiety, \u0000Abstrak \u0000Tujuan: Untuk mendeteksi kecemasan sebelum tindakan seksio sesarea elektif dan emergensi. \u0000Metode: Penelitian ini merupakan suatu penelitian cross-sectional. Jumlah sampel penelitian 42 sampel terdiri dari 21 pasien hamil dengan rencana seksio sesarea elektif dan 21 pasien hamil dengan rencana seksio sesarea emergensi di RSUP Prof. Dr. R. D. Kandou Manado dan RS Jejaring di Kota Manado dari bulan Maret 2021 sampai bulan Juni 2021. Kecemasan dinilai melalui pemeriksaan kortisol serum dan tingkat kecemasan menurut kusioner Hamilton (HAM-A). Data kemudian dianalisis dengan menggunakan software SPSS versi 23.0. \u0000Hasil: Kadar kortisol secara rata-rata lebih tinggi pada seksio sesarea emergensi (mean 21.590±11.6392) dibandingkan dengan seksio sesarea elektif (mean 10.586±4.9501). Tingkat kecemasan menurut skor HAM-A secara rata-rata lebih tinggi pada seksio sesarea emergensi (mean 15.33±7.722) dibandingkan dengan seksio sesarea elektif (mean 7.19±3.614). \u0000Kesimpulan: Terdapat korelasi positif bermakna antara kadar kortisol dan tingkat kecemasan berdasarkan skor HAM-A pada semua subjek penelitian. \u0000Kata kunci: kortisol, seksio sesarea,  skor HAM-A. kecemasan","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49454949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sexual Function in Female of Reproductive Age Post Total Hysterectomy 全子宫切除术后育龄女性性功能的变化
Indonesian Journal of Obstetrics and Gynecology Pub Date : 2022-10-30 DOI: 10.32771/inajog.v10i4.1535
Yonathan D Onibala, Bismarck J. Laihad, Rudy A. Lengkong
{"title":"Sexual Function in Female of Reproductive Age Post Total Hysterectomy","authors":"Yonathan D Onibala, Bismarck J. Laihad, Rudy A. Lengkong","doi":"10.32771/inajog.v10i4.1535","DOIUrl":"https://doi.org/10.32771/inajog.v10i4.1535","url":null,"abstract":"Background: Sexual intercourse and having offspring are essential in a household to live because they are determinant of marital happiness. Many women reported increasing sexual function after hysterectomy; meanwhile, others complained about sexual dysfunction after the hysterectomy procedure. \u0000Objective: To determine the effect of sexual function on women of reproductive age after a total hysterectomy \u0000Method: This study is a descriptive retrospective study with a cross-sectional study design. \u0000Results: This study is based on the data of 23 samples that met the inclusion criteria. With 11 samples increasing FSFI score, 11 samples with a decreasing of FSFI score and 1 sample had an unchanged sexual function before and after surgery. Then from those 23 samples, 16 samples with Female Sexual Dysfunction (FSD) have FSFI score of less than or equal to 26.55 before surgery, and 17 samples with FSD after surgery. Based on the T-Test, there were significant differences between the Female Sexual Function Index (FSFI) before and after the surgery. Most of the respondents experienced decreasing sexual satisfaction (14 samples), while only five samples experienced increased sexual satisfaction and the other four samples had unchanged sexual satisfaction. In our study, most of the respondents (17 samples) claimed that there were better or decreased pain after the hysterectomy procedure. While there were only three samples that claimed an increase of pain, and only three samples claimed that there was unchanged pain scale. \u0000Conclusion: There were changes in sexual function before and after hysterectomy as measured by Female Sexual Function Index (FSFI) \u0000Key Words : Sexual function, FSFI, before hysterectomy, after hysterectomy","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43310899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of serum magnesium, calcium, and potassium levels on the event of calf muscle cramps, according to the perspective of pregnant women in the third-trimester of pregnancy 血清镁、钙和钾水平对小腿肌肉痉挛事件的影响,根据妊娠晚期孕妇的观点
Indonesian Journal of Obstetrics and Gynecology Pub Date : 2022-10-30 DOI: 10.32771/inajog.v10i4.1586
Cut N. Maracilu, Cut M. Yeni, H. Hasanuddin, Hilwah Nora, Sarah I. Nainggolan
{"title":"The effect of serum magnesium, calcium, and potassium levels on the event of calf muscle cramps, according to the perspective of pregnant women in the third-trimester of pregnancy","authors":"Cut N. Maracilu, Cut M. Yeni, H. Hasanuddin, Hilwah Nora, Sarah I. Nainggolan","doi":"10.32771/inajog.v10i4.1586","DOIUrl":"https://doi.org/10.32771/inajog.v10i4.1586","url":null,"abstract":" Objective: To determine the effect of magnesium, calcium, and potassium levels on calf muscle cramps in third-trimester pregnant women at Dr. Zainoel Abidin Banda Aceh. \u0000Methods: This research is an observational analytic study with a case-control method by taking samples using a total sampling technique. The research sample was third-trimester pregnant women (28-40 weeks of gestation) who were treated in the maternity ward for the period September to December 2020. \u0000Results: A total of 263 samples were involved in this study where 105 patients (40%) were obese, 229 patients (87%) were housewives, 161 patients (61%) did not experience muscle cramps and samples had magnesium levels below normal as much as 82 people, calcium levels below normal as many as 127 people and potassium levels below normal as many as 2 people. The mean levels of magnesium, calcium, and potassium were 1.8 mg/dL, 8.69 mg/dL, and 4.25 mmol/L, respectively. The results of this study are magnesium levels affect muscle cramps in pregnant women (p-value=0.000), while calcium levels (p-value=0.373) and potassium (p-value=0.062) do not affect muscle cramps in pregnant women. \u0000Conclusion: There is a significant effect between magnesium levels on the incidence of calf muscle cramps in third-trimester pregnant women, while calcium and potassium levels do not affect them. \u0000Keywords: Muscle Cramps, Magnesium, Calcium, Potassium.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41899085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutrition versus Great Obstetric Syndrome: A Bridge too Far? 营养与产科综合征:一座太远的桥?
Indonesian Journal of Obstetrics and Gynecology Pub Date : 2022-10-30 DOI: 10.32771/inajog.v10i4.1856
Hermanto T. Joewono
{"title":"Nutrition versus Great Obstetric Syndrome: A Bridge too Far?","authors":"Hermanto T. Joewono","doi":"10.32771/inajog.v10i4.1856","DOIUrl":"https://doi.org/10.32771/inajog.v10i4.1856","url":null,"abstract":"<jats:p>N/A</jats:p>","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43156485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of Isolated Tubal Torsion (ALADIN) during Emergency Laparotomy in Infertile Women 不孕妇女急诊剖腹术中孤立性输卵管扭转的处理
Indonesian Journal of Obstetrics and Gynecology Pub Date : 2022-10-30 DOI: 10.32771/inajog.v10i4.1582
Bella Aprilia, Raymond Surya, Bram Pradipta
{"title":"Management of Isolated Tubal Torsion (ALADIN) during Emergency Laparotomy in Infertile Women","authors":"Bella Aprilia, Raymond Surya, Bram Pradipta","doi":"10.32771/inajog.v10i4.1582","DOIUrl":"https://doi.org/10.32771/inajog.v10i4.1582","url":null,"abstract":"Introduction: Isolated tubal torsion (ITT) is rare cases with challenging to diagnose. We would like to report ITT and primary infertility patient which came with acute abdominal pain. \u0000Case: A 36 yo female came to Koja Hospital with acute abdominal pain without sign of infections. Ultrasound findings show cystic mass on bilateral adnexal sized 76x28x39 mm and 31x51x43 mm with minimal ascites. During laparotomy, proximal right fallopian tube was torsioned four times clockwise. There was hydrosalping founded on contralateral tube, while right and left ovaries and uterus were normal. We performed salpingectomy. \u0000Discussion: The clinical presentation of ITT is non-specific and it has become a challenge to physician to develop preoperative diagnosis. The spectrum of imaging findings may be wide range depending on adnexal pathology, degree of severity, and the duration of adnexal torsion. The recommendation of primary approach to tubal torsion is conservative management considering ALADIN (mALignAncy-Death tissue, INfertility). \u0000Conclusion: The diagnosis is rarely be made before operation, due to non-specific clinical symptoms and imaging findings. The considerations to perform conservative management are malignancy, death tissue/necrotic, and infertility.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43357036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sociodemographic Factors of Elective and Emergency Cesarean Delivery in the Referal Hospital: A cross-sectional study 转诊医院择期和急诊剖宫产的社会人口因素:一项横断面研究
Indonesian Journal of Obstetrics and Gynecology Pub Date : 2022-10-30 DOI: 10.32771/inajog.v10i4.1613
Restuaji B.K. Umam, N. I. Purnamasari, I. Sudayasa, Juminten Saimin
{"title":"Sociodemographic Factors of Elective and Emergency Cesarean Delivery in the Referal Hospital: A cross-sectional study","authors":"Restuaji B.K. Umam, N. I. Purnamasari, I. Sudayasa, Juminten Saimin","doi":"10.32771/inajog.v10i4.1613","DOIUrl":"https://doi.org/10.32771/inajog.v10i4.1613","url":null,"abstract":"Objectives: To analyze the correlation between sociodemographic factors and cesarean section delivery at Referral Hospital in Kendari.  \u0000Method: This was a cross-sectional study conducted at dr. Ismoyo Hospital in Kendari. Data were obtained from medical records of cesarean section delivery from January to December 2019. Sampling used simple random sampling techniques. Data were analyzed using the Chi-square test. \u0000Result: There were 50.5% emergency cesarean and 49.5% elective cesarean. The maternal age was 18-44 years. Most cases are aged 20-35 years (78.5%), have a higher education level (65.1%), employees (53.2%), and  multipara (56.5%). There was a correlation between age and cesarean section (p = 0.027). There was no correlation between education level (p = 0.618), occupation (p = 0.563), and parity (p = 0.365) with cesarean section. \u0000Conclusion: There is a correlation between maternal age and cesarean section. Education, counseling, and antenatal care should be done for early detection. \u0000Keywords: age, cesarean section, education level, occupation, parity","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46781399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Level of maternal zinc serum as risk factor of preeclampsia 母亲血清锌水平与子痫前期危险因素的关系
Indonesian Journal of Obstetrics and Gynecology Pub Date : 2022-10-30 DOI: 10.32771/inajog.v10i4.1616
Tia Kaprianti, Putri Mirani, A. Martadiansyah, P. M. Lestari, Theodorus Theodorus
{"title":"Level of maternal zinc serum as risk factor of preeclampsia","authors":"Tia Kaprianti, Putri Mirani, A. Martadiansyah, P. M. Lestari, Theodorus Theodorus","doi":"10.32771/inajog.v10i4.1616","DOIUrl":"https://doi.org/10.32771/inajog.v10i4.1616","url":null,"abstract":"Objective : To know the relationship of serum zinc levels with preeclampsia (PE) \u0000Method: This observational research uses a type of case control research. The population of this study is all pregnant women with a single pregnancy, gestational age of 28-42 weeks who were treated at the Department of Obstetrics and Gynecology of RSUP Dr. Mohammad Hoesin Palembang from August 2020 to November 2020. The study divided into 2 group, a case group of 30 pregnant women with PE and a control group of 60 pregnant women non PE. Serum zinc level examination is performed on all samples that match the research criteria. The data is processed by using SPSS software program version 20.0 Windows. \u0000Result: Both case and control groups had no meaningful differences to the general characteristics of the patient. There were significant differences in average zinc levels of maternal serum in both research groups (p=0.013; 43.90 plus-minus 15.79 pg/dL). The value of serum zinc levels that have the best sensitivity and specificity is at 45.5 pg/dL. \u0000Conclusion: There is a meaningful relationship between serum zinc levels and PE events. Pregnant women with serum zinc levels greater than or equal to 45.5 pg /dL were significantly at 3.2 times more risk of PE than pregnant women with serum zinc levels less than or equal to 45.5 pg/dL. In this case it is necessary to supplement zinc earlier in pregnancy to reduce the risk of preeclampsia. Keywords: preeclampsia, zinc, case-control studies","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43087426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful pregnancy after hCG/hMG treatment in an azoospermic male with idiopathic hypogonadotropic hypogonadism hCG/hMG治疗原发性促性腺功能减退症的无精子症男性后成功妊娠
Indonesian Journal of Obstetrics and Gynecology Pub Date : 2022-10-30 DOI: 10.32771/inajog.v10i4.1604
G. Jeon, C. Park
{"title":"Successful pregnancy after hCG/hMG treatment in an azoospermic male with idiopathic hypogonadotropic hypogonadism","authors":"G. Jeon, C. Park","doi":"10.32771/inajog.v10i4.1604","DOIUrl":"https://doi.org/10.32771/inajog.v10i4.1604","url":null,"abstract":"Idiopathic hypogonadotropic hypogonadism (IHH) is one of the correctable causes of male infertility. Although there have been several previous reports about fertility treatment for IHH, there are no established guidelines of therapeutic method yet. We present an azoospermic male of IHH who succeeded in pregnancy and full term live birth after 18 months of treatment with human chorionic gonadotropin (hCG)/human menopausal gonadotropin (hMG), and then changed his treatment into testosterone replacement therapy to maintain an appropriate male hormone level. This case report shows that a thorough and careful examination of whether it is a reversible cause is necessary and important in the approach to male infertility. In addition, it further proves that, in the case of IHH, a continuous long-term gonadotrophic stimulation therapy contributes to successful pregnancy and may need a testosterone replacement therapy after birth.","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47574032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response of External Radiotherapy Alone in Stage IIB – IIIC Cervical Cancer Patients 单纯外放疗治疗IIB - IIIC期宫颈癌的疗效观察
Indonesian Journal of Obstetrics and Gynecology Pub Date : 2022-07-31 DOI: 10.32771/inajog.v10i3.1575
Antonius Wibowo, B. J. Laihad, S. Mongan, Enrico Napitupulu
{"title":"Response of External Radiotherapy Alone in Stage IIB – IIIC Cervical Cancer Patients","authors":"Antonius Wibowo, B. J. Laihad, S. Mongan, Enrico Napitupulu","doi":"10.32771/inajog.v10i3.1575","DOIUrl":"https://doi.org/10.32771/inajog.v10i3.1575","url":null,"abstract":"Objective: To investigate the therapeutic response and toxicity in cervical cancer patients with stage IIB-IIIC who undergo external radiation. \u0000Methods: This was a retrospective study using the medical records of the Obstetric Oncology and Radiotherapy Department at Prof. Dr. R. D. Kandou Hospital Manado. The research subjects were stage IIB-IIIC cervical cancer patients who underwent external radiation from September 2016 to December 2020. External radiation was administrated using 60Cobalt. The statistical analysis assessments in this study was carried out using descriptive analysis, while the analysis of the relationship was carried out using the Chi-Square method. The toxicity assessments were carried out from first day started external radiation up until 1 month after the therapy was deemed completed. \u0000Results : As many as 413 cervical cancer patients underwent external radiation during the study. However, only 192 cervical cancer patients with stage IIB-IIIC met the inclusion criteria in this study. The complete response to the therapy based on the findings was 65.6%, the partial response was 31.8%, the stable response was 1.6%, and the progressive response was 1%. In statistical analysis there was a significant association between cervical cancer stage and Overall Treatment Time with response to external radiotherapy. However, no significant association between tumor size and histopathological type with response to external radiotherapy. There were hematological toxicity (45.8%), skin toxicity (45.3%), gastrointestinal toxicity (6.3%) and urinary tract toxicity (2.6%). \u0000Conclusions: External radiotherapy response was a complete response where there was an association between cervical cancer stage and Overall Treatment Time with response to external radiotherapy, whereas there is no significant association found between the tumor size and histopathological type based on this research's findings. Most toxicity were hematology with complaints of anemia and thrombocytopenia \u0000Keywords: cervical cancer, external radiation response, toxicity. \u0000  \u0000Abstrak \u0000  \u0000Tujuan: Untuk mengetahui respon terapi dan efek samping pasien kanker serviks stadium IIB-IIIC yang menjalani radioterapi eksterna. \u0000Metode: Penelitian ini adalah penelitian deskriptif rektrospektif dengan menggunakan rekam medis Poli Onkologi Kandungan dan Instalasi Radioterapi RSUP Prof. Dr. R. D. Kandou Manado. Subyek penelitian adalah pasien kanker serviks stadium IIB-IIIC yang menjalani radiasi eksterna mulai September 2016 sampai Desember 2020. Radiasi eksterna dilakukan dengan sinar 60Cobalt. Penilaian analisis statistika pada penelitian ini menggunakan analisis deskriptif dan analisis hubungan menggunakan metode Chi Square. Penilaian efek samping dilakukan sejak hari pertama pasien memulai radiasi eksterna sampai 1 bulan setelah dinyatakan selesai menjalani radioterapi eksterna. \u0000Hasil: Selama periode penelitian didapatkan 413 pasien kanker serviks yang menjalani radiasi eksterna nam","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43176372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
C-Reactive Protein and Matrix Metalloproteinase-7 in Preterm Premature Rupture of Membranes (PPROM) and Premature Rupture of Membranes (PROM) c -反应蛋白和基质金属蛋白酶-7在早产儿早破膜(PPROM)和早破膜(PROM)中的作用
Indonesian Journal of Obstetrics and Gynecology Pub Date : 2022-07-31 DOI: 10.32771/inajog.v10i3.1574
Rajuddin Rajuddin, Tgk Chairannisa Putri, Munawar
{"title":"C-Reactive Protein and Matrix Metalloproteinase-7 in Preterm Premature Rupture of Membranes (PPROM) and Premature Rupture of Membranes (PROM)","authors":"Rajuddin Rajuddin, Tgk Chairannisa Putri, Munawar","doi":"10.32771/inajog.v10i3.1574","DOIUrl":"https://doi.org/10.32771/inajog.v10i3.1574","url":null,"abstract":"Objective: To determine the difference in qualitative serum CRP and MMP-7 levels between PROM and PPROM \u0000Methods: Research with a case-control design with premature rupture of membranes in term pregnancy as a control group and preterm pregnancy as a case group conducted in the delivery room of the Regional General Hospital dr. Zainoel Abidin Banda Aceh starting from January 2020. Total number of each group as many as 30 samples that met the inclusion and exclusion criteria by taking venous blood samples to check the levels of qualitative CRP serum and levels of the Metalloproteinase-7 Matrix (MMP-7). Statistical tests for categorical - numerical data groups were tested using independent sample t-test and categorical - categorical data groups were tested using Chi-Square test. \u0000Results: A total of 60 samples with 30 PPROM and 30 PROM mothers. There was no statistically significant difference in the qualitative CRP serum result in PROM patients with term and preterm pregnancies. On MMP-7 examination, the mean MMP-7 level of preterm PROM mothers was higher than at term PROM, which was 5.28 mg / L and there was a significant relationship between MMP-7 and qualitative CRP in PROM patients with term pregnancy (p <0.05). \u0000Conclusion: There is no significant difference in the value of qualitative CRP and MMP-7 between PPROM and PROM. However, there was a significant association between qualitative serum CRP and plasma MMP-7 in PROM. \u0000Keywords: c-reactive protein, matrix metalloproteinase-7,rupture of membranes. \u0000  \u0000Abstrak \u0000Tujuan: Untuk mengetahui perbedaan gambaran serum CRP kualitatif dan kadar MMP-7 antara kehamilan preterm dan aterm dengan ketuban pecah dini di RSUD  Dr. Zainoel Abidin Banda Aceh. \u0000Metode: Penelitian dengan desain kasus kontrol dengan ketuban pecah dini kehamilan aterm sebagai kelompok kontrol dan kehamilan preterm sebagai kelompok kasus. yang dilakukan di Kamar Bersalin Rumah Sakit Umum Daerah dr. Zainoel Abidin Banda Aceh pada Januari 2020. Dengan jumlah masing-masing kelompok sebanyak 30 sampel yang memenuhi kriteria inklusi dan eklusi dengan pengambilan sampel darah vena untuk dilakukan pemeriksaan kadar serum CRP kualitatif dan kadar Matrix Metalloproteinase-7 (MMP-7). Uji statistik untuk kelompok data yang bersifat kategorik - numerik diuji menggunakan uji T tidak berpasangan dan pasangan kelompok data yang bersifat kategorik - katergorik akan diuji menggunakan uji Chi-Square. \u0000Hasil: Sebanyak 60 penderita KPD dengan 30 Ibu KPD Preterm dan 30 KPD aterm. Tidak dijumpai perbedaan yang bermakna secara statistik gambaran serum CRP kualitatif pada penderita KPD dengan kehamilan aterm dan preterm. Pada pemeriksaan MMP-7 rerata kadar MMP-7 ibu KPD preterm lebih tinggi dibandingkan KPD  aterm yakni senilai 5,28 mg/L dan terdapat hubungan bermakna antara MMP-7 dan CRP kualitatif pada penderita KPD dengan kehamilan aterm (p < 0,05). \u0000Kesimpulan: Tidak terdapat perbedaan gambaran signifikan nilai CRP kualitatif dan MMP-7 antara KPD prete","PeriodicalId":13477,"journal":{"name":"Indonesian Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44174893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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