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Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry最新文献

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Synthesis, computational studies and antioxidant activity of some 3-(2-alkylamino-4-aminothiazole-5-oyl) pyridines 几种3-(2-烷基氨基-4-氨基噻唑-5-酰基)吡啶的合成、计算研究及抗氧化活性
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-06-29 DOI: 10.56042/ijcb.v60i4.32001
{"title":"Synthesis, computational studies and antioxidant activity of some 3-(2-alkylamino-4-aminothiazole-5-oyl) pyridines","authors":"","doi":"10.56042/ijcb.v60i4.32001","DOIUrl":"https://doi.org/10.56042/ijcb.v60i4.32001","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":"48 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73268083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Selective aerobic oxidation of benzylic and allylic alcohols catalyzed by Cu(OAc)2/TEMPO/Et2NH Cu(OAc)2/TEMPO/ et2nhh催化苯丙醇和烯丙醇选择性好氧氧化
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-06-29 DOI: 10.56042/ijcb.v60i4.39062
{"title":"Selective aerobic oxidation of benzylic and allylic alcohols catalyzed by Cu(OAc)2/TEMPO/Et2NH","authors":"","doi":"10.56042/ijcb.v60i4.39062","DOIUrl":"https://doi.org/10.56042/ijcb.v60i4.39062","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":"15 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90503584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and biological evaluation of thiazolidinedione derivatives of chalcones and flavones as antihyperglycemic and antidyslipidemic agents 查尔酮类和黄酮类噻唑烷二酮类抗高血糖和降血脂药物的合成及生物学评价
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-06-29 DOI: 10.56042/ijcb.v60i4.38425
{"title":"Synthesis and biological evaluation of thiazolidinedione derivatives of chalcones and flavones as antihyperglycemic and antidyslipidemic agents","authors":"","doi":"10.56042/ijcb.v60i4.38425","DOIUrl":"https://doi.org/10.56042/ijcb.v60i4.38425","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":"44 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74498650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design, synthesis and evaluation of thiazole based amides for their antitubercular and PknG inhibitory activity 噻唑类酰胺的设计、合成及抗结核和抑制pkg活性的评价
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-06-29 DOI: 10.56042/ijcb.v60i4.37131
{"title":"Design, synthesis and evaluation of thiazole based amides for their antitubercular and PknG inhibitory activity","authors":"","doi":"10.56042/ijcb.v60i4.37131","DOIUrl":"https://doi.org/10.56042/ijcb.v60i4.37131","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":"30 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74280595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and antimicrobial activities of thiadiazole containing quinoline derivatives 含喹啉噻二唑衍生物的合成及抗菌活性研究
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-06-29 DOI: 10.56042/ijcb.v60i4.33705
{"title":"Synthesis and antimicrobial activities of thiadiazole containing quinoline derivatives","authors":"","doi":"10.56042/ijcb.v60i4.33705","DOIUrl":"https://doi.org/10.56042/ijcb.v60i4.33705","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88903453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis, characterization and evaluation of new thiazole derivatives as anthelmintic agents 新型噻唑类驱虫剂的合成、表征及评价
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-06-29 DOI: 10.56042/ijcb.v60i4.29285
{"title":"Synthesis, characterization and evaluation of new thiazole derivatives as anthelmintic agents","authors":"","doi":"10.56042/ijcb.v60i4.29285","DOIUrl":"https://doi.org/10.56042/ijcb.v60i4.29285","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":"2 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84586617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Silica sulfuric acid catalyzed green synthesis of 1,2- dihydro-1-aryl naphtho[1,2-e][1,3]-oxazin-3-one and 1,2- dihydro-1-methyl naphtho[1,2-e][1,3]-oxazin-3-one as potent antibacterial agents 二氧化硅硫酸催化绿色合成1,2-二氢-1-芳基萘[1,2-e][1,3]-恶嗪-3- 1和1,2-二氢-1-甲基萘[1,2-e][1,3]-恶嗪-3- 1作为高效抗菌剂
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-06-29 DOI: 10.56042/ijcb.v60i4.32326
{"title":"Silica sulfuric acid catalyzed green synthesis of 1,2- dihydro-1-aryl naphtho[1,2-e][1,3]-oxazin-3-one and 1,2- dihydro-1-methyl naphtho[1,2-e][1,3]-oxazin-3-one as potent antibacterial agents","authors":"","doi":"10.56042/ijcb.v60i4.32326","DOIUrl":"https://doi.org/10.56042/ijcb.v60i4.32326","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":"12 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90037031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis, crystal structure, density functional theory, Hirshfeld surface analysis and molecular docking studies of 2-(2-phenylanthracen-9-yl)thiophene derivatives 2-(2-苯基蒽-9-基)噻吩衍生物的合成、晶体结构、密度泛函理论、Hirshfeld表面分析及分子对接研究
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-03-16 DOI: 10.56042/ijcb.v60i3.34731
R. Manickam, G. Jagadeesan, G. Srinivasan
{"title":"Synthesis, crystal structure, density functional theory, Hirshfeld surface analysis and molecular docking studies of 2-(2-phenylanthracen-9-yl)thiophene derivatives","authors":"R. Manickam, G. Jagadeesan, G. Srinivasan","doi":"10.56042/ijcb.v60i3.34731","DOIUrl":"https://doi.org/10.56042/ijcb.v60i3.34731","url":null,"abstract":"Thiophene containing molecules have been distinguished as potential candidates in the largely emergent chemical world of heterocyclic compounds that show likely pharmacological characteristics. The knowledge of a mixture of synthetic pathways and the different physicochemical parameters of such compounds describe the especial interest of medicinal chemists to produce combinatorial collections and carry out in-depth efforts in the search of lead molecules. Among the various group of compounds studied, thiophene moieties stand out as unique in features due to their biological, pharmacological and medicinal properties. Synthesis, crystal structure, conformation and density functional theory of 2-(2-phenylanthracen-9-yl)thiophene derivative have been investigated in detail. Thiophene moiety are in planar conformation and having C-H…O type of hydrogen bonds and Van der Waals forces. Density functional theory has been applied to the thiophene derivative. Thiophene compounds score highly against the targeted protein and can be compared to the co-crystal ligand. Hirshfeld surface studies have been used to confirm and quantify the supramolecular features.","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":"18 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79174150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A short review: Chemistry of thioisatin and its derivatives 综述:硫代硫甙及其衍生物的化学性质
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-03-16 DOI: 10.56042/ijcb.v60i3.31392
S. Singh
{"title":"A short review: Chemistry of thioisatin and its derivatives","authors":"S. Singh","doi":"10.56042/ijcb.v60i3.31392","DOIUrl":"https://doi.org/10.56042/ijcb.v60i3.31392","url":null,"abstract":"In recent years, the thioisatin (benzo[b]thiophene-2,3-diones) have attracted considerable attention due to their ability to act as intermediates in the preparation of a series of fused spiroheterocycles. The benzothiophenic frameworks are important targets in synthetic and medicinal chemistry because this fragment is a key moiety in a wide number of natural and synthetic agents. Subsequently the present study deals with the synthesis of a variety of spiroheterocycles for which different strategies have been evolved viz. [4+2] photocycloaddition (spiropyrans), cyclocondensation (benzodiazocine), nucleophilic cyclization (spirothioazolidinones) and air oxidation (disulfides). semicarbazide reacts with thioisatin at 3‑position (thiosemicarbazones, 2-hydroxy-(2 H )-3,3-diaryl- and 3-hydroxy-3 H -2,2-diaryl-benzo[b]thiophenes hydroxyl compounds), 4,9-dimethylthiophanthrenes.","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":"39 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89150665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Synthesis and antimicrobial activity of chalcone containing polystyrene 含聚苯乙烯查尔酮的合成及其抑菌活性
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-03-16 DOI: 10.56042/ijcb.v60i3.34156
{"title":"Synthesis and antimicrobial activity of chalcone containing polystyrene","authors":"","doi":"10.56042/ijcb.v60i3.34156","DOIUrl":"https://doi.org/10.56042/ijcb.v60i3.34156","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":"94 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2021-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86712452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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