发布求助
文献互助 智能选刊 最新文献

Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry最新文献

筛选
英文 中文
Synthesis, DFT calculations, NBO analysis and docking studies of 3-(2-arylamino-4-aminothiazol-5-oyl)pyridine derivatives 3-(2-芳基氨基-4-氨基噻唑-5-酰基)吡啶衍生物的合成、DFT计算、NBO分析及对接研究
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-10-05 DOI: 10.56042/ijcb.v60i7.29123
{"title":"Synthesis, DFT calculations, NBO analysis and docking studies of 3-(2-arylamino-4-aminothiazol-5-oyl)pyridine derivatives","authors":"","doi":"10.56042/ijcb.v60i7.29123","DOIUrl":"https://doi.org/10.56042/ijcb.v60i7.29123","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79414167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modulation of morphology and efficacy of new CB1 receptor antagonist using simple and benign polymeric additives 新型CB1受体拮抗剂的形态和疗效的简单和良性聚合物添加剂调节
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-10-05 DOI: 10.56042/ijcb.v60i7.29319
{"title":"Modulation of morphology and efficacy of new CB1 receptor antagonist using simple and benign polymeric additives","authors":"","doi":"10.56042/ijcb.v60i7.29319","DOIUrl":"https://doi.org/10.56042/ijcb.v60i7.29319","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80726112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Montmorillonite K-10 supported palladium nanoparticles: A catalyst for the preparation of α-aminoynones employing copper free acyl Sonogashira reaction 蒙脱土K-10负载钯纳米颗粒:用无铜酰基Sonogashira反应制备α-氨基酮的催化剂
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-10-05 DOI: 10.56042/ijcb.v60i7.37777
{"title":"Montmorillonite K-10 supported palladium nanoparticles: A catalyst for the preparation of α-aminoynones employing copper free acyl Sonogashira reaction","authors":"","doi":"10.56042/ijcb.v60i7.37777","DOIUrl":"https://doi.org/10.56042/ijcb.v60i7.37777","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81400617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis of isomeric Naphtho furanyl Coumarins as Anti-inflammatory and Analgesic Agents 抗炎镇痛异构体萘呋喃基香豆素的合成
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-10-05 DOI: 10.56042/ijcb.v60i7.29262
{"title":"Synthesis of isomeric Naphtho furanyl Coumarins as Anti-inflammatory and Analgesic Agents","authors":"","doi":"10.56042/ijcb.v60i7.29262","DOIUrl":"https://doi.org/10.56042/ijcb.v60i7.29262","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73914833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design and synthesis of new quinoline hybrid derivatives and their antimicrobial, antimalarial and antitubercular activities 新型喹啉杂化衍生物的设计与合成及其抗菌、抗疟、抗结核活性
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-10-05 DOI: 10.56042/ijcb.v60i7.28981
{"title":"Design and synthesis of new quinoline hybrid derivatives and their antimicrobial, antimalarial and antitubercular activities","authors":"","doi":"10.56042/ijcb.v60i7.28981","DOIUrl":"https://doi.org/10.56042/ijcb.v60i7.28981","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83047579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Synthesis, molecular docking and biological evaluation of new quinoline analogues as potent anti-breast cancer and antibacterial agents 新型喹啉类抗乳腺癌抗菌剂的合成、分子对接及生物学评价
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-10-01 DOI: 10.22034/IJPS.2020.120884.1637
S. V. Rathod, Kailas W. Shinde, P. Kharkar, C. Shah
{"title":"Synthesis, molecular docking and biological evaluation of new quinoline analogues as potent anti-breast cancer and antibacterial agents","authors":"S. V. Rathod, Kailas W. Shinde, P. Kharkar, C. Shah","doi":"10.22034/IJPS.2020.120884.1637","DOIUrl":"https://doi.org/10.22034/IJPS.2020.120884.1637","url":null,"abstract":"A series of new class of quinoline analogues were synthesized from isatin through two steps in good yields. All compounds were further evaluated for their anticancer activity against triple-negative breast cancer cell line (MDA-MB-231) using MTT assay and antibacterial activity against Gram-positive bacteria (Staphylococcus aureus 6538p and Bacillus subtilis) and Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa) using agar well diffusion method. All synthesized compounds were confirmed by spectral characterization viz FT-IR, MS, 1H-NMR and 13C-NMR. Results indicated that in vitro anticancer evaluation, IC50 values of all target compounds were found to be in the range of 11.50-37.99 µM and compound 4h showed better promising anti-breast cancer activity among all synthesized derivatives. In vitro antibacterial evaluation, compounds 4d, 4f, 4h and 4j exhibited moderate antibacterial activity against all tested organisms. Molecular docking analysis demonstrated good interaction of compound 4h with the active site residue of Human Carbonic Anhydrase I, Protein Kinase A and Kinesin Spindle Protein (KSP).","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83562165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design, synthesis and antibacterial activity of 9-aryl-6-(2-naphthyl) [1,2,4]triazolo[4,3-a][1,8]naphthyridines 9-芳基-6-(2-萘基)[1,2,4]三唑[4,3-a][1,8]萘啶的设计、合成及抑菌活性研究
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-07-29 DOI: 10.56042/ijcb.v60i6.43827
{"title":"Design, synthesis and antibacterial activity of 9-aryl-6-(2-naphthyl) [1,2,4]triazolo[4,3-a][1,8]naphthyridines","authors":"","doi":"10.56042/ijcb.v60i6.43827","DOIUrl":"https://doi.org/10.56042/ijcb.v60i6.43827","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91093461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis, characterization, cytotoxicity evaluation and physicochemical properties of some novel N4-substituted aminobenzenesulfonamides 几种新型n4取代氨基磺酰胺的合成、表征、细胞毒性评价及理化性质
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-07-29 DOI: 10.56042/ijcb.v60i6.43707
{"title":"Synthesis, characterization, cytotoxicity evaluation and physicochemical properties of some novel N4-substituted aminobenzenesulfonamides","authors":"","doi":"10.56042/ijcb.v60i6.43707","DOIUrl":"https://doi.org/10.56042/ijcb.v60i6.43707","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73701774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Ammonium chloride catalyzed Knoevenagel condensation in PEG-400 as ecofriendly solvent 氯化铵作为环保溶剂在PEG-400中催化Knoevenagel缩合
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-07-29 DOI: 10.56042/ijcb.v60i6.28094
{"title":"Ammonium chloride catalyzed Knoevenagel condensation in PEG-400 as ecofriendly solvent","authors":"","doi":"10.56042/ijcb.v60i6.28094","DOIUrl":"https://doi.org/10.56042/ijcb.v60i6.28094","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81074792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Analogues designing for dephosphorylation of acetylcholinesterase enzyme 乙酰胆碱酯酶去磷酸化类似物的设计
IF 0.5 4区 化学
Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry Pub Date : 2021-07-29 DOI: 10.56042/ijcb.v60i6.28544
{"title":"Analogues designing for dephosphorylation of acetylcholinesterase enzyme","authors":"","doi":"10.56042/ijcb.v60i6.28544","DOIUrl":"https://doi.org/10.56042/ijcb.v60i6.28544","url":null,"abstract":"","PeriodicalId":13458,"journal":{"name":"Indian Journal of Chemistry Section B-organic Chemistry Including Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2021-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90580410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信