Indian Journal of Health Sciences and Biomedical Research (KLEU)最新文献_第5页

Metastatic cystic melanoma of unknown primary masquerading as sarcoma: Report of a rare occurrence 伪装成肉瘤的不明原发转移性囊性黑色素瘤:罕见病例报告

Indian Journal of Health Sciences and Biomedical Research (KLEU) Pub Date : 2023-05-01 DOI: 10.4103/kleuhsj.kleuhsj_189_22

K. Mardi, A. Mehta, Rashpal Thakur

引用次数: 0

Incidence of inflammatory reactions after intravitreal injection of a biosimilar of ranibizumab for the treatment of various retinal vascular conditions 用于治疗各种视网膜血管疾病的雷尼单抗生物仿制药玻璃体内注射后炎症反应的发生率

Indian Journal of Health Sciences and Biomedical Research (KLEU) Pub Date : 2023-05-01 DOI: 10.4103/kleuhsj.kleuhsj_234_21

V. Wani, A. Agarwal, A. Tenagi, Bhagyajyothi B. Khanagavi, S. Bubanale, Nagbhushan S Chougule, Chethana Warad

{"title":"Incidence of inflammatory reactions after intravitreal injection of a biosimilar of ranibizumab for the treatment of various retinal vascular conditions","authors":"V. Wani, A. Agarwal, A. Tenagi, Bhagyajyothi B. Khanagavi, S. Bubanale, Nagbhushan S Chougule, Chethana Warad","doi":"10.4103/kleuhsj.kleuhsj_234_21","DOIUrl":"https://doi.org/10.4103/kleuhsj.kleuhsj_234_21","url":null,"abstract":"BACKGROUND: Razumab is a biosimilar of ranibizumab and its intravitreal injection in various retinal diseases has been reported with good results. However, the incidence of inflammation in the anterior chamber and vitreous after the intravitreal injection of Razumab has not been studied so far. AIMS OF THE STUDY: The aim of this study was to study the incidence of inflammatory reaction in the anterior chamber and vitreous after intravitreal Razumab. MATERIALS AND METHODS: It was a single-center, nonrandomized observational study of eyes that received intravitreal Razumab injection for various retinal indications. The eyes were examined for anterior chamber and vitreous reaction at regular intervals. Preinjection and postinjection visual acuity and intraocular pressure (IOP) were noted. STATISTICAL ANALYSIS: The proportion of eyes developing anterior chamber and vitreous reaction were calculated with confidence intervals. The pre- and postinjection visual acuity and IOP were compared by Student's t-test for significant changes. RESULTS: Eighty-two injections were performed in 40 eyes of 33 patients. Four eyes (4.8%) showed anterior chamber reaction among which one eye had vitreous reaction also. All four eyes had no adverse effect on visual acuity and recovered completely. Mean preinjection logMAR visual acuity of 0.69 ± 0.41 improved to 0.58 ± 0.38 postinjection (P < 0.0001). The mean preinjection IOP changed from 16.2 ± 3.9 mmHg to 14.7 ± 3.4 mmHg postinjection (P = 0.009). CONCLUSIONS: The incidence of inflammatory reaction was found to be higher with Razumab compared to the incidence reported in the literature for ranibizumab. However, visual acuity was not affected by this inflammatory reaction.","PeriodicalId":13457,"journal":{"name":"Indian Journal of Health Sciences and Biomedical Research (KLEU)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90286875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mustadi Yapana Basti (medicated enema) in the management of oligozoospermia: A case series 药物灌肠在治疗少精症中的应用:一个病例系列

Indian Journal of Health Sciences and Biomedical Research (KLEU) Pub Date : 2023-05-01 DOI: 10.4103/kleuhsj.kleuhsj_178_23

A. Tanwar, Sujata Rajan, Manoj K. Shamkuwar

{"title":"Mustadi Yapana Basti (medicated enema) in the management of oligozoospermia: A case series","authors":"A. Tanwar, Sujata Rajan, Manoj K. Shamkuwar","doi":"10.4103/kleuhsj.kleuhsj_178_23","DOIUrl":"https://doi.org/10.4103/kleuhsj.kleuhsj_178_23","url":null,"abstract":"Infertility is a global issue of concern in the modern era, affecting 8%–12% of couples globally. Although the etiology of infertility is varied and difficult to determine, a good proportion of cases can be attributed to male. The most common cause of male infertility is oligozoospermia. Oligozoospermia is a decrease in sperm concentration below 15 million sperm/ml in semen ejaculate. Shukra Kshaya is a similar clinical condition mentioned in Ayurveda in which the Shukra Dhatu is diminished both qualitatively and quantitatively. Ayurveda has specified many therapeutic interventions and practices, including the Panchakarma procedure, Basti Karma, for the strengthening of Shukra Dhatu as well as the management of Shukra-Dusht. Mustadi Yapana Basti (MYB) was chosen for this study because of its significant Vatahara, Rasayana, and Vajikarana characteristics. A total of 05 patients who were diagnosed with oligozoospermia were managed with MYB for 15 consecutive days without any internal medications. The Shukra Kshaya assessment questionnaire was used in conjunction with objective parameters to determine the improvement. Data were collected twice before and after therapy. After the treatment, all five participants exhibited significant improvement in sperm count from a mean of 10.4–55. In this case series, all the patients demonstrated clinical improvement in symptoms of Shukra kshaya as well as in associated laboratory parameters. Basti treatment significantly improved all symptoms of Shukra Kshaya, as well as semen parameters (sperm count, sperm active motility, and semen volume) and serum testosterone. The reported cases demonstrate that MYB is a therapeutic option for the comprehensive care of men with a diagnosis of oligozoospermia.","PeriodicalId":13457,"journal":{"name":"Indian Journal of Health Sciences and Biomedical Research (KLEU)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87032613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary fallopian tube carcinoma: Preoperative diagnostic dilemma 原发性输卵管癌:术前诊断困境

Indian Journal of Health Sciences and Biomedical Research (KLEU) Pub Date : 2023-05-01 DOI: 10.4103/kleuhsj.kleuhsj_677_22

S. Bhalla, Shalini Rawat, Sameer Gupta

引用次数: 0

Spectrum of incidental tumors in autopsy specimens: A histopathological analysis of 797 cases 尸检标本附带肿瘤谱:797例组织病理学分析

Indian Journal of Health Sciences and Biomedical Research (KLEU) Pub Date : 2023-05-01 DOI: 10.4103/kleuhsj.kleuhsj_624_22

B. Mohan, Lesitha Sivaraman, Surekha Vijayan, Aathira Das

{"title":"Spectrum of incidental tumors in autopsy specimens: A histopathological analysis of 797 cases","authors":"B. Mohan, Lesitha Sivaraman, Surekha Vijayan, Aathira Das","doi":"10.4103/kleuhsj.kleuhsj_624_22","DOIUrl":"https://doi.org/10.4103/kleuhsj.kleuhsj_624_22","url":null,"abstract":"INTRODUCTION: Autopsy supplemented with histopathological examination is important in finding the cause and manner of death. Although not common, neoplastic lesions are encountered in autopsy specimens. AIM: The aim of this study was to analyze the various incidental tumors (both benign and malignant) in medicolegal autopsies. MATERIALS AND METHODS: In this retrospective study, a total of 797 medicolegal autopsies done over a period of 2 years (January 2019–December 2020) were analyzed. Cases in which tumors were diagnosed were selected and details including age, gender, death scenario, and other relevant histopathological findings were noted in each of these. RESULTS: We noted 46 tumors out of 797 cases (5.8%). 18 (39.1%) were benign and 28 (60.9%) were malignant. Rare tumors such as central neurocytoma, diffuse astrocytoma, colonic schwannoma, and oligocystic serous cystadenoma of the pancreas were noted. CONCLUSIONS: We found 5.8% of neoplastic lesions in this study. Although the histopathological findings of neoplasms in the autopsies may not contribute to identifying the cause of death in most cases, there have been interesting cases that are a prime focus of academic and research data.","PeriodicalId":13457,"journal":{"name":"Indian Journal of Health Sciences and Biomedical Research (KLEU)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74121331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Community knowledge, attitude, and practices for protection against the malaria: A cross-sectional study in a rural area of aspirational district in Haryana, India 社区预防疟疾的知识、态度和实践:印度哈里亚纳邦理想地区农村地区的横断面研究

Indian Journal of Health Sciences and Biomedical Research (KLEU) Pub Date : 2023-05-01 DOI: 10.4103/kleuhsj.kleuhsj_605_22

Ashutosh Kumar Singh, R. Rai, Sanjeet Panesar, Vikas Gupta

{"title":"Community knowledge, attitude, and practices for protection against the malaria: A cross-sectional study in a rural area of aspirational district in Haryana, India","authors":"Ashutosh Kumar Singh, R. Rai, Sanjeet Panesar, Vikas Gupta","doi":"10.4103/kleuhsj.kleuhsj_605_22","DOIUrl":"https://doi.org/10.4103/kleuhsj.kleuhsj_605_22","url":null,"abstract":"INTRODUCTION: Malaria poses a great socioeconomic burden on humanity as it affects the majority of countries in the tropical and subtropical regions. The estimated number of malaria deaths stood at 445,000 in 2016, a similar to the previous year (446,000). This study was conducted with the aim to assess community knowledge, attitude, and practices (KAPs) for protection against the malaria. MATERIALS AND METHODS: This was community-based with a cross-sectional study conducted for 4 months in the 6 villages under the subcenter Sangail, with household as a sampling unit, and study participants were selected by randomized multistage sampling technique. A pretested, predesigned, standardized questionnaire with close-ended responses was developed for data collection. All tests were performed at a 5% level of significance. RESULTS: In the present study, more than one-fifth of participants believed that malaria is due to the wrath of almighty (22.3%) or bad air (30.2%), the restrain was observed in about half of households (54.5%) for indoor indoor residual spray, half of the participants strongly believed that malaria is not a public health issue (45.3%) and more than three-fourth of households (34.8%) were still preferring to sleep outside of their homes. CONCLUSION: KAP of malaria and its control was observed to be low among the study population. Misconceptions about malaria transmission still exist. The result of this study will bring forward the health-care workers with the desired need for health education and promotion on malaria at the first contact either in the health facilities or in the patient's family house on home visit.","PeriodicalId":13457,"journal":{"name":"Indian Journal of Health Sciences and Biomedical Research (KLEU)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86844264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Model rural health research unit's NS1-based serosurveillance recommends for vector control in rural villages of Jaipur district, Rajasthan, India 示范农村卫生研究单位基于ns1的服务监测建议在印度拉贾斯坦邦斋浦尔地区的农村进行病媒控制

Indian Journal of Health Sciences and Biomedical Research (KLEU) Pub Date : 2023-05-01 DOI: 10.4103/kleuhsj.kleuhsj_570_22

C. Meena, Supriya Chouhan, Suresh Yadav, Mahendra Thakor, S. Mohanty

{"title":"Model rural health research unit's NS1-based serosurveillance recommends for vector control in rural villages of Jaipur district, Rajasthan, India","authors":"C. Meena, Supriya Chouhan, Suresh Yadav, Mahendra Thakor, S. Mohanty","doi":"10.4103/kleuhsj.kleuhsj_570_22","DOIUrl":"https://doi.org/10.4103/kleuhsj.kleuhsj_570_22","url":null,"abstract":"Background: Infectious diseases are important public health issues in India. Rajasthan state reported 20,749 numbers of dengue fever (DF) cases in 2021, which was 10.73% of the country's total dengue cases. Aims and objectives: The aim of the study was to diagnose fever cases in the nearby villages of Model Rural Health Research Unit (MRHRU) through the use of its diagnostic facility and to mitigate the diseases using appropriate control methods. MATERIALS AND METHODS: This is a community health center (CHC)-based serosurveillance study. The study subjects were the patients who reported at the Outpatient Department of the CHCs Bhanpur Kalan and Jamwa Ramgarh of Jaipur district in Rajasthan with clinical suspicion of DF. The study was conducted for 6 months from July to December. The serum samples received from CHC Bhanpur Kalan and Jamwa Ramgarh were tested for the detection of dengue antibodies against NS1 antigen at MRHRU. Results: A total of 148 blood samples were received from CHC and were diagnosed with dengue NS1 at MRHRU. Out of 148 serum samples, 79 were male and 69 were female. Among the 148 samples subjected to the NS1 dengue enzyme-linked immunosorbent assay test, 33.1% were found to be positive for dengue, 63.5% were negative, and 3.37% were equivocal. Out of the 113 samples of Jamwa Ramgarh, 31.8% were found to be NS1 positive and 2.65% were equivocal, wherein 35 serum samples of Amber block were tested for diagnosis of NS1 test, and out of them, 37.14% were NS1 positive and 5.71% were equivocal. Conclusion: The number of dengue cases was observed to be higher, and control measure was taken to stop the spreading of the disease. Early and proper diagnosis of dengue cases is helpful in the treatment and control of disease. MRHRU facility was found to be effective in the containment of the disease.","PeriodicalId":13457,"journal":{"name":"Indian Journal of Health Sciences and Biomedical Research (KLEU)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85729463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Innovation in health care – A roadmap for this paradigm shift 卫生保健的创新——这一范式转变的路线图

Indian Journal of Health Sciences and Biomedical Research (KLEU) Pub Date : 2023-05-01 DOI: 10.4103/kleuhsj.kleuhsj_376_23

P. Angadi

引用次数: 0

Clinicoepidemiological profile of severe acute malnutrition children admitted to the nutritional rehabilitation center of a tertiary care center in Davangere: A retrospective study 达万热某三级保健中心营养康复中心收治的严重急性营养不良儿童的临床流行病学概况:一项回顾性研究

Indian Journal of Health Sciences and Biomedical Research (KLEU) Pub Date : 2023-05-01 DOI: 10.4103/kleuhsj.kleuhsj_485_22

Shalini Hurlihal, G. Vidya, R. Varalakshmi

{"title":"Clinicoepidemiological profile of severe acute malnutrition children admitted to the nutritional rehabilitation center of a tertiary care center in Davangere: A retrospective study","authors":"Shalini Hurlihal, G. Vidya, R. Varalakshmi","doi":"10.4103/kleuhsj.kleuhsj_485_22","DOIUrl":"https://doi.org/10.4103/kleuhsj.kleuhsj_485_22","url":null,"abstract":"BACKGROUND: Severe acute malnutrition (SAM) is a major public health problem which the world is facing right now. Nineteen million children in the world are suffering from SAM. The current study was undertaken to study the clinicoepidemiological profile and the treatment outcome of SAM children admitted to the nutritional rehabilitation center (NRC). MATERIALS AND METHODS: A retrospective record-based study was carried out in children with SAM and those who were admitted to NRC during the period of 1 year (March 2018–2019) were included in the study. One hundred and eighteen children were included in the study. RESULTS: Seventy-one (60.16%) belonged to the age group of 1–2 years. Sixty-five (55.08%) presented with symptoms related to gastrointestinal tract, followed by respiratory tract 38 (32.20%). 55.08% of children were cured from SAM after NRC admission. CONCLUSION: NRC provides lifesaving treatment measures for SAM children. The most common symptom in SAM children was symptom of gastrointestinal tract and children were cured from SAM after NRC admission.","PeriodicalId":13457,"journal":{"name":"Indian Journal of Health Sciences and Biomedical Research (KLEU)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80907971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and predictors of stress during COVID pandemic among health-care workers in India: A systematic review 印度卫生保健工作者在COVID大流行期间的压力流行率和预测因素:系统综述

Indian Journal of Health Sciences and Biomedical Research (KLEU) Pub Date : 2023-05-01 DOI: 10.4103/kleuhsj.kleuhsj_165_22

Janmejaya Samal, B. Datta, Subbanna Jonnalagada

{"title":"Prevalence and predictors of stress during COVID pandemic among health-care workers in India: A systematic review","authors":"Janmejaya Samal, B. Datta, Subbanna Jonnalagada","doi":"10.4103/kleuhsj.kleuhsj_165_22","DOIUrl":"https://doi.org/10.4103/kleuhsj.kleuhsj_165_22","url":null,"abstract":"The COVID-19 pandemic is one of its kinds of public health emergencies that the world is grappling with. The health-care workers (HCWs) were at the forefront of the battle against this scourge. As a result of continuous service delivery, they experienced stress and burnout which varied from the type of HCWs, gender, type of service, and the length of service rendered by them. Given the context, this systematic review assessed the prevalence and predictors of stress among different types of HCWs in India. The systematic review was conducted using PubMed search engine and 13 articles were selected for the purpose of review. Of the 13 studies identified, 11 studies were carried out predominantly in India or in some Indian states and 2 studies were multinational studies, in which samples were also drawn from India. Of these 13 studies, 6, 5, 3, 2, and 2 studies were conducted among the doctors, specialists, nurses, dentists, and allied HCWs in India, respectively. It was observed that the prevalence of stress among HCWs varied with age, gender, type of HCWs, place of work, and duration of work, and the predictors were long working hours, continuous contact with patients, fear of self-infection, stigmatization, and fear of carrying the infection to the family. Stress and burnout among HCWs are inevitable; however, there should be ways and means to have coping behavior else the same would affect the professionals' personal life and patient care. Hence, appropriate measures need to be taken to address this issue by the HCWs themselves, government, and other social sectors organizations.","PeriodicalId":13457,"journal":{"name":"Indian Journal of Health Sciences and Biomedical Research (KLEU)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82007922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0