J. D. Sharma, Upasana Kalita, Muktanjalee Deka, B. Bharadwaj, Adahra Patriesa Beso
{"title":"Juvenile granulosa cell tumor in a 35-year-old pregnant woman: A rare case report","authors":"J. D. Sharma, Upasana Kalita, Muktanjalee Deka, B. Bharadwaj, Adahra Patriesa Beso","doi":"10.32677/ijcr.v10i2.4357","DOIUrl":"https://doi.org/10.32677/ijcr.v10i2.4357","url":null,"abstract":"Juvenile granulosa cell tumors (JGCTs) account for 5% of GCT and 3% are diagnosed after 30 years of age. JGCT is an uncommon neoplasm in pregnancy. About 90% are stage I at diagnosis but advanced-stage tumors are aggressive often resulting in recurrence or death within 3 years of diagnosis. We present a case of JGCT in a pregnant woman of 35 years old. The patient complained of sudden onset pain in her second trimester. Ultrasound whole abdomen was done and a malignant lesion was detected. Subsequently, the left ovarian cystectomy was performed and a diagnosis of JGCT was given which was confirmed by histopathology and immunohistochemistry.","PeriodicalId":13365,"journal":{"name":"Indian Journal of Case Reports","volume":"23 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140438594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sebin Sebastian Sebastian, Pushependra Malik, Chanderbhan Bhan, M. K. Garg, Prakash Raj Ujjalsingh
{"title":"Aggressive debridement and early antifungal therapy in the management of cutaneous mucormycosis: A case report with review of literature","authors":"Sebin Sebastian Sebastian, Pushependra Malik, Chanderbhan Bhan, M. K. Garg, Prakash Raj Ujjalsingh","doi":"10.32677/ijcr.vi.4318","DOIUrl":"https://doi.org/10.32677/ijcr.vi.4318","url":null,"abstract":"Mucormycosis is an infectious disease caused by fungi. The worldwide spread of coronavirus disease-19 did create a public health crisis, infecting millions of people and causing huge numbers of deaths worldwide. Cutaneous manifestations of mucormycosis can either be primary or secondary diseases. Clinical manifestations can vary from cellulitis, abscess, or ulcer. Standard management includes early diagnosis, surgical debridement, and antifungal therapy. Early initiation of antifungal therapy can lower mortality rates and improve the prognosis of patients. The estimated mortality ranges from 25% to 87%, depending on the site of infection.","PeriodicalId":13365,"journal":{"name":"Indian Journal of Case Reports","volume":"33 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140441496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fatima Abubakar Rasheed, Asma'u Usman, Aisha Abdurrahman, Umar Usman Aliyu, Ibrahim Yakasai
{"title":"Florid vulvar warts in a 39-year-old human immunodeficiency virus-positive woman: A case report","authors":"Fatima Abubakar Rasheed, Asma'u Usman, Aisha Abdurrahman, Umar Usman Aliyu, Ibrahim Yakasai","doi":"10.32677/ijcr.v10i2.4373","DOIUrl":"https://doi.org/10.32677/ijcr.v10i2.4373","url":null,"abstract":"Condyloma acuminata are human papillomavirus (HPV) infections frequently caused by HPV serotypes 6 and 11 that affect both sexes and are particularly infectious, recurrent, and negatively impact the quality of life of affected individuals. It is linked with the human immunodeficiency virus (HIV), is usually more aggressive and florid, and occurs at multiple sites with prevailing treatment difficulties in HIV-positive individuals. We present a curious case of florid vulvar warts in a 39-year-old HIV-positive woman.","PeriodicalId":13365,"journal":{"name":"Indian Journal of Case Reports","volume":"23 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140441090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vishal M Hadiya, Alok Mathur, Mohammad Izhar Joad, Latika Damariya, Mahesh Choudhary, JB Gupta
{"title":"Recurrent statin-induced rhabdomyolysis: Commonly overlooked drug","authors":"Vishal M Hadiya, Alok Mathur, Mohammad Izhar Joad, Latika Damariya, Mahesh Choudhary, JB Gupta","doi":"10.32677/ijcr.v10i2.4299","DOIUrl":"https://doi.org/10.32677/ijcr.v10i2.4299","url":null,"abstract":"Statin-induced muscle pain and myopathy are common. However, statin-induced rhabdomyolysis causing severe nephropathy is somehow uncommon. Here, we present the case of a 68-year-old patient on statin therapy after percutaneous coronary intervention. We want to highlight the fact that physicians should differentiate muscle pain without biochemical derangement and with severe rhabdomyolysis leading to acute kidney injury and hyperkalemia. Patients should be made aware of this commonly overlooked drug causing severe complications.","PeriodicalId":13365,"journal":{"name":"Indian Journal of Case Reports","volume":"11 47","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139957514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sandya Rani Padma Guruvelli, Vandana Gangadharan, S. S. K. Prakash, Bhagyalakshmi Atla
{"title":"Solitary plasmacytoma: A case report","authors":"Sandya Rani Padma Guruvelli, Vandana Gangadharan, S. S. K. Prakash, Bhagyalakshmi Atla","doi":"10.32677/ijcr.v10i2.4368","DOIUrl":"https://doi.org/10.32677/ijcr.v10i2.4368","url":null,"abstract":"Plasmacytoma is a discrete, unifocal, and monoclonal neoplastic proliferation of plasma cells. It may present as one of the three distinct clinical entities: multiple myeloma (MM), solitary plasmacytoma of the bone, and extramedullary plasmacytoma. Solitary plasmacytoma of the bone accounts for 3% of all plasma cell neoplasms. About 50% of the cases of solitary plasmacytoma of the bone transform into MM. The most commonly involved sites are vertebrae and long bones. It is extremely rare in jaws. We are presenting a case of solitary plasmacytoma of the maxilla in a 59-year-old female patient with comprehensive clinical, radiological, histological, and immunohistochemical features.","PeriodicalId":13365,"journal":{"name":"Indian Journal of Case Reports","volume":"22 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140440206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdullah Zaawari, Muralidhar Varma, P. Tirlangi, M. Harsha, Deepthi Avvaru
{"title":"Metformin-dolutegravir interaction leads to metformin-associated lactic acidosis: A case report","authors":"Abdullah Zaawari, Muralidhar Varma, P. Tirlangi, M. Harsha, Deepthi Avvaru","doi":"10.32677/ijcr.v10i2.4371","DOIUrl":"https://doi.org/10.32677/ijcr.v10i2.4371","url":null,"abstract":"Metformin, a biguanide, is considered the standard first-line drug for managing type 2 diabetes mellitus (T2DM) patients owing to its safety profile. Despite having a highly safe profile, it is capable of causing serious adverse effects. Biguanides decrease gluconeogenesis from alanine, pyruvate, and lactate, which may result in lactic acidosis. The risk is high in patients with polypharmacy or comorbidities. This is a case of a 48-year-old Indian female with a known case of human immunodeficiency virus (HIV), T2DM, hypothyroidism, and hypertension who presented to the hospital with progressive right-sided weakness for the past 10 days along with transit loss of vision. The patient was diagnosed with multiple central nervous system tuberculomas, for which antitubercular treatment and dexamethasone were started. The patient was on a tenofovir, lamivudine, and dolutegravir regimen for HIV. The patient was started on metformin for sugar control, which led to metformin-associated lactic acidosis. A drug interaction between dolutegravir and metformin was attributed to this. The patient improved after metformin was replaced with glipizide, and lactate levels returned to normal. Lactic acidosis is a rare side effect of metformin. However, the risk of lactic acidosis is high when another drug interferes with metformin pharmacokinetics. Proper assessment and evaluation of potential drug–drug interactions is crucial to assure safe and effective therapy.","PeriodicalId":13365,"journal":{"name":"Indian Journal of Case Reports","volume":"63 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140439292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Somarajan Anandan, Jyothish P Kumar, Divine S Shajee, Leena Latheef
{"title":"Hippocampal dot sign in transient global amnesia","authors":"Somarajan Anandan, Jyothish P Kumar, Divine S Shajee, Leena Latheef","doi":"10.32677/ijcr.vi.4370","DOIUrl":"https://doi.org/10.32677/ijcr.vi.4370","url":null,"abstract":"","PeriodicalId":13365,"journal":{"name":"Indian Journal of Case Reports","volume":"22 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140440207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unilateral interstitial lung disease: A unique manifestation of asymptomatic pulmonary artery atresia","authors":"Akriti Gujral, Namita Singh, Giriraj Singh, Ankush Bansal","doi":"10.32677/ijcr.v10i2.4364","DOIUrl":"https://doi.org/10.32677/ijcr.v10i2.4364","url":null,"abstract":"Interstitial pulmonary fibrosis is idiopathic, bilateral, or secondary to exposure to organic antigens, or collagen disorders. Unilateral pulmonary fibrosis is uncommon and intriguing as it has different pathogenetic mechanisms. We present a case of a patient with a short 5-day history of dyspnea with no ailment in childhood. His radiograph revealed increased reticular markings in the right lung with a small right hilum. Contrast-enhanced computed tomography showed unilateral pulmonary fibrosis and confirmed the presence of an atretic right pulmonary artery contributing to the small hilum, with collateral supply from the right internal mammary artery. This asymptomatic patient had unilateral pulmonary fibrosis which had developed as a consequence of impaired blood supply to the right lung due to atresia of the right pulmonary artery with collateral from systemic circulation unable to keep abreast with normal pulmonary development.","PeriodicalId":13365,"journal":{"name":"Indian Journal of Case Reports","volume":"19 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140438853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A rare presentation of jejunal GIST: A case report","authors":"Pranjit Kalita, Arnab Gupta, Piyas Sengupta, Samir Bhattacharyya","doi":"10.32677/ijcr.v10i1.4347","DOIUrl":"https://doi.org/10.32677/ijcr.v10i1.4347","url":null,"abstract":"Gastrointestinal stromal tumors (GISTs) are rare tumors that constitute 1% of all GI tract tumors. Jejunal GISTs are the rarest subtype. We present a middle-aged gentleman, who presented with pain in the right lower abdomen. On abdominal examination, a lump was palpable in the right iliac fossa (RIF). Contrast-enhanced computed tomography of the abdomen revealed an extraluminal soft-tissue mass in the ileum. Computed Tomography-guided core needle biopsy from the lump was consistent with GIST, which was confirmed on immunohistochemistry. Mutation analysis revealed exon 11 mutations. Due to the proximity of GIST to the rectum and urinary bladder, the patient was started on imatinib therapy. After 3 months of treatment, imatinib therapy had to be stopped due to skin reactions. Restaging was done with a positron-emission tomography scan, which demonstrated a soft-tissue mass likely arising from the ileocecal region in the RIF abutting the ascending colon without any significant decrease in size. On exploration, a well-circumscribed mobile extraluminal lobulated mass was seen arising from the antimesenteric border of the jejunum. Histopathologic examination showed GIST, which was confirmed on immunohistochemistry. We report this case to emphasize keeping small bowel GIST as an unusual differential diagnosis of a RIF lump. Furthermore, not all patients can tolerate imatinib treatment, hence exon mutation study is important, and surgery should be considered if it is deemed resectable.","PeriodicalId":13365,"journal":{"name":"Indian Journal of Case Reports","volume":"6 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139867486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exposure keratopathy secondary to lagophthalmos with facial nerve palsy – Challenges in management","authors":"Muhammad Arif Ozir, Syaratul Emma Hashim","doi":"10.32677/ijcr.v10i1.4352","DOIUrl":"https://doi.org/10.32677/ijcr.v10i1.4352","url":null,"abstract":"Exposure keratopathy is a corneal damage that occurs from prolonged exposure of the ocular surface to the outside environment. Exposure keratopathy can lead to keratitis, ulceration, and cornea scarring. Lagophthalmos is the inability to close the eyelid completely and this leads to a portion of the eye remaining open and subject to cornea damage. Here, we describe the 72-year-old man with a case of exposure keratopathy secondary to facial nerve palsy with complications of cornea ulceration and scarring that cause permanent vision loss. We discuss difficult challenges during management from medical to surgical management.","PeriodicalId":13365,"journal":{"name":"Indian Journal of Case Reports","volume":"52 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139867864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}