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C1 activation by amyloid β fibrils. Evidence for a binding site for Aβ on the C1q globular regions β淀粉样蛋白原纤维激活C1。在C1q球状区发现a β结合位点的证据
Immunopharmacology Pub Date : 2000-08-01 Epub Date: 2002-07-10 DOI: 10.1016/S0162-3109(00)80039-9
P Tacnet , M Galvan , S Chevallier , C Glabe , A.J. Tenner , G.J. Arlaud
{"title":"C1 activation by amyloid β fibrils. Evidence for a binding site for Aβ on the C1q globular regions","authors":"P Tacnet , M Galvan , S Chevallier , C Glabe , A.J. Tenner , G.J. Arlaud","doi":"10.1016/S0162-3109(00)80039-9","DOIUrl":"10.1016/S0162-3109(00)80039-9","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"49 1","pages":"Page 16"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0162-3109(00)80039-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84240538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Should we use probiotics as supportive treatment for hereditary angioedema? 我们是否应该使用益生菌作为遗传性血管性水肿的支持治疗?
Immunopharmacology Pub Date : 2000-08-01 Epub Date: 2002-07-10 DOI: 10.1016/S0162-3109(00)80082-X
Kazimierz Madalinski, Hanna Jaworska, Hanna Gregorek
{"title":"Should we use probiotics as supportive treatment for hereditary angioedema?","authors":"Kazimierz Madalinski, Hanna Jaworska, Hanna Gregorek","doi":"10.1016/S0162-3109(00)80082-X","DOIUrl":"10.1016/S0162-3109(00)80082-X","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"49 1","pages":"Page 26"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0162-3109(00)80082-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"97345786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amyloid plaques in a transgenic mouse model of Alzheimer's disease (AD) contain complement components and pro-inflammatory cytokines 阿尔茨海默病(AD)转基因小鼠模型中的淀粉样斑块含有补体成分和促炎细胞因子
Immunopharmacology Pub Date : 2000-08-01 Epub Date: 2002-07-10 DOI: 10.1016/S0162-3109(00)80012-0
J.X. Yu , B.M. Bradt , K. Hsiao , N.R. Cooper
{"title":"Amyloid plaques in a transgenic mouse model of Alzheimer's disease (AD) contain complement components and pro-inflammatory cytokines","authors":"J.X. Yu , B.M. Bradt , K. Hsiao , N.R. Cooper","doi":"10.1016/S0162-3109(00)80012-0","DOIUrl":"10.1016/S0162-3109(00)80012-0","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"49 1","pages":"Page 7"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0162-3109(00)80012-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83831264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Characterization of the human CR1-like transcript 人类cr1样转录物的表征
Immunopharmacology Pub Date : 2000-08-01 Epub Date: 2002-07-10 DOI: 10.1016/S0162-3109(00)80022-3
Daniel J. Birmingham, Christine M. Logar, Wei Chen
{"title":"Characterization of the human CR1-like transcript","authors":"Daniel J. Birmingham, Christine M. Logar, Wei Chen","doi":"10.1016/S0162-3109(00)80022-3","DOIUrl":"10.1016/S0162-3109(00)80022-3","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"49 1","pages":"Page 11"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0162-3109(00)80022-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113756014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
C4-A like and C4-B like animal models C4-A类和C4-B类动物模型
Immunopharmacology Pub Date : 2000-08-01 Epub Date: 2002-07-10 DOI: 10.1016/S0162-3109(00)80024-7
M. Gadjeva, M. Carroll
{"title":"C4-A like and C4-B like animal models","authors":"M. Gadjeva, M. Carroll","doi":"10.1016/S0162-3109(00)80024-7","DOIUrl":"10.1016/S0162-3109(00)80024-7","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"49 1","pages":"Page 12"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0162-3109(00)80024-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78590526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative expression of anaphylatoxin C3a and C5a receptors on lung bronchial epithelial and smooth muscle cells in mouse models of asthma and sepsis 哮喘和脓毒症小鼠模型肺支气管上皮细胞和平滑肌细胞中过敏毒素C3a和C5a受体的比较表达
Immunopharmacology Pub Date : 2000-08-01 Epub Date: 2002-07-10 DOI: 10.1016/S0162-3109(00)80081-8
Scott M. Drouin , Jens Kildsgaard , Joie Haviland , Hong Pen Jia , Paul B. McCray , Brian F. Tack , Rick A. Wetsel
{"title":"Comparative expression of anaphylatoxin C3a and C5a receptors on lung bronchial epithelial and smooth muscle cells in mouse models of asthma and sepsis","authors":"Scott M. Drouin , Jens Kildsgaard , Joie Haviland , Hong Pen Jia , Paul B. McCray , Brian F. Tack , Rick A. Wetsel","doi":"10.1016/S0162-3109(00)80081-8","DOIUrl":"10.1016/S0162-3109(00)80081-8","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"49 1","pages":"Page 26"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0162-3109(00)80081-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77887858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Human C6 deficiency has a homogeneous genetic background 人类C6缺乏症具有同质的遗传背景
Immunopharmacology Pub Date : 2000-08-01 Epub Date: 2002-07-10 DOI: 10.1016/S0162-3109(00)80033-8
V. Frémeaux-Bacchi, M.A. Durey, J. Blouin, M.D. Kazatchkine
{"title":"Human C6 deficiency has a homogeneous genetic background","authors":"V. Frémeaux-Bacchi, M.A. Durey, J. Blouin, M.D. Kazatchkine","doi":"10.1016/S0162-3109(00)80033-8","DOIUrl":"10.1016/S0162-3109(00)80033-8","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"49 1","pages":"Page 14"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0162-3109(00)80033-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76301435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tissue expression pattern of the mouse GPI-DAF and its potential role in a murine model of autoimmune disease 小鼠GPI-DAF的组织表达模式及其在小鼠自身免疫性疾病模型中的潜在作用
Immunopharmacology Pub Date : 2000-08-01 Epub Date: 2002-07-10 DOI: 10.1016/S0162-3109(00)80076-4
Miwa T , Maldonado M , Sun X , Ohta R , Okada H , Harris C , Morgan BP , Eisenberg RA , Song WC
{"title":"Tissue expression pattern of the mouse GPI-DAF and its potential role in a murine model of autoimmune disease","authors":"Miwa T , Maldonado M , Sun X , Ohta R , Okada H , Harris C , Morgan BP , Eisenberg RA , Song WC","doi":"10.1016/S0162-3109(00)80076-4","DOIUrl":"10.1016/S0162-3109(00)80076-4","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"49 1","pages":"Page 25"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0162-3109(00)80076-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78023095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Initial characterization of the Cobra Venom Factor gene 眼镜蛇毒因子基因的初步表征
Immunopharmacology Pub Date : 2000-08-01 Epub Date: 2002-07-10 DOI: 10.1016/S0162-3109(00)80025-9
Holger Bammert , Bärbel Kunze , David C. Fritzinger , Reinhard Bredehorst , Jörg Andrä , Carl-Wilhelm Vogel
{"title":"Initial characterization of the Cobra Venom Factor gene","authors":"Holger Bammert , Bärbel Kunze , David C. Fritzinger , Reinhard Bredehorst , Jörg Andrä , Carl-Wilhelm Vogel","doi":"10.1016/S0162-3109(00)80025-9","DOIUrl":"10.1016/S0162-3109(00)80025-9","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"49 1","pages":"Page 12"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0162-3109(00)80025-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"104294766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phenotypes of complement knockouts. 补体基因敲除的表型。
Immunopharmacology Pub Date : 2000-08-01 DOI: 10.1016/s0162-3109(00)80298-2
V M Holers
{"title":"Phenotypes of complement knockouts.","authors":"V M Holers","doi":"10.1016/s0162-3109(00)80298-2","DOIUrl":"https://doi.org/10.1016/s0162-3109(00)80298-2","url":null,"abstract":"<p><p>Although complete and partial complement deficiencies are well described in humans and several spontaneous animal models, many questions have remained regarding the exact role that these deficiency states play in the observed clinical manifestations. Likewise, many important mechanistic questions cannot be addressed using patients or spontaneously arising animal models of deficiency states. To provide additional insights and create readily manipulable experimental systems, over the last 5 years mice have been created by several groups in which specifically targeted insertional mutagenesis has resulted in complete deficiencies of complement activation proteins, receptors or regulatory proteins. Many surprising findings have already been made using mice derived from these strategies, and clinically relevant studies have begun to provide great insights into human deficiency states. This review includes an overview of these complement deficient mice and highlights some of the important findings that have resulted from their creation. A discussion of future experimental directions thought to be important by this author then follows and concludes the review.</p>","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"49 1-2","pages":"125-31"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/s0162-3109(00)80298-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21745167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 39
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