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Immunopharmacology Pub Date : 2000-09-01 Epub Date: 2000-09-14 DOI: 10.1016/S0162-3109(00)00273-3
{"title":"Index","authors":"","doi":"10.1016/S0162-3109(00)00273-3","DOIUrl":"https://doi.org/10.1016/S0162-3109(00)00273-3","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"49 3","pages":"Pages 425-427"},"PeriodicalIF":0.0,"publicationDate":"2000-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0162-3109(00)00273-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136490530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of a pectic polysaccharide from a medicinal herb, the roots of Bupleurum falcatum L. on interleukin 6 production of murine B cells and B cell lines 中药柴胡根果胶多糖对小鼠B细胞和B细胞系白细胞介素6产生的影响
Immunopharmacology Pub Date : 2000-09-01 Epub Date: 2000-09-14 DOI: 10.1016/S0162-3109(00)00245-9
Yingjie Guo , Tsukasa Matsumoto , Yuji Kikuchi , Takashi Ikejima , Benxiang Wang , Haruki Yamada
{"title":"Effects of a pectic polysaccharide from a medicinal herb, the roots of Bupleurum falcatum L. on interleukin 6 production of murine B cells and B cell lines","authors":"Yingjie Guo ,&nbsp;Tsukasa Matsumoto ,&nbsp;Yuji Kikuchi ,&nbsp;Takashi Ikejima ,&nbsp;Benxiang Wang ,&nbsp;Haruki Yamada","doi":"10.1016/S0162-3109(00)00245-9","DOIUrl":"10.1016/S0162-3109(00)00245-9","url":null,"abstract":"<div><p><span>The effect of T-cell-independent B cell mitogen<span>, a pectic polysaccharide, bupleuran 2IIc, from a medicinal herb, the roots of </span></span><span><em>Bupleurum</em><em> falcatum</em></span><span> L. on interleukin 6 (IL-6) production of murine B cells and B cell lines was investigated in order to clarify the mechanism of enhanced immunoglobulin<span> (Ig) secretion from B cells. Bupleuran 2IIc enhanced IgM secretion from highly purified murine normal B cells. When normal B cells from murine spleen were cultured with bupleuran 2IIc in the presence of anti-IL-6 neutralizing antibody, the enhanced IgM secretion by bupleuran 2IIc was reduced. When B cells were stimulated with bupleuran 2IIc, their IL-6 secretion and the transcription of IL-6 mRNA were enhanced. The enhanced IL-6 secretion by bupleuran 2IIc was also observed in B cell line, Y16 cell. When bupleuran 2IIc was digested with endo-α-(1→4)-</span></span><span>d</span>-polygalacturonase, the resulting enzyme resistant carbohydrate portion, “ramified” region (PG-1) composed of rhamnogalacturonan core containing neutral sugar side chains showed potent IL-6 secretion-enhancing activity. These results suggest that the “ramified” region of bupleuran 2IIc stimulates the secretion of IL-6 as the active site, and the resulting IL-6 may partially contribute the enhancement of IgM secretion as an autocrine and/or paracrine mechanism.</p></div>","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"49 3","pages":"Pages 307-316"},"PeriodicalIF":0.0,"publicationDate":"2000-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0162-3109(00)00245-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"21829602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 47
Cobra Venom Factor (CVF) reduces hypoxicischemic (HI) cerebral edema in neonatal rats 眼镜蛇毒因子(CVF)减少新生大鼠缺氧缺血性脑水肿
Immunopharmacology Pub Date : 2000-08-01 Epub Date: 2002-07-10 DOI: 10.1016/S0162-3109(00)80065-X
H Lassiter, P Feldhoff, N Dabhia, J Parker, R Feldhoff
{"title":"Cobra Venom Factor (CVF) reduces hypoxicischemic (HI) cerebral edema in neonatal rats","authors":"H Lassiter,&nbsp;P Feldhoff,&nbsp;N Dabhia,&nbsp;J Parker,&nbsp;R Feldhoff","doi":"10.1016/S0162-3109(00)80065-X","DOIUrl":"10.1016/S0162-3109(00)80065-X","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"49 1","pages":"Page 22"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0162-3109(00)80065-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75085685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of immunoglobulins, complement and phagocyte in children anb adolescents with diabetes mellitus type 1 儿童和青少年1型糖尿病患者免疫球蛋白、补体和吞噬细胞的分析
Immunopharmacology Pub Date : 2000-08-01 Epub Date: 2002-07-10 DOI: 10.1016/S0162-3109(00)80083-1
RDR Liberatore Jr. , SFC Barbosa , MGA Alkimin , R Bellinati-Pires , MPC Florido , L Isaac , M. Kirschfink , AS Grumach
{"title":"Analysis of immunoglobulins, complement and phagocyte in children anb adolescents with diabetes mellitus type 1","authors":"RDR Liberatore Jr. ,&nbsp;SFC Barbosa ,&nbsp;MGA Alkimin ,&nbsp;R Bellinati-Pires ,&nbsp;MPC Florido ,&nbsp;L Isaac ,&nbsp;M. Kirschfink ,&nbsp;AS Grumach","doi":"10.1016/S0162-3109(00)80083-1","DOIUrl":"10.1016/S0162-3109(00)80083-1","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"49 1","pages":"Page 27"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0162-3109(00)80083-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"105356626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular cloning of CIR/CIS-like serine protease from the common carp 鲤鱼CIR/ cis样丝氨酸蛋白酶的分子克隆
Immunopharmacology Pub Date : 2000-08-01 Epub Date: 2002-07-10 DOI: 10.1016/S0162-3109(00)80021-1
Miki Nakao, Kazunori Osaka, Yoko Kato, Tomoki Yano
{"title":"Molecular cloning of CIR/CIS-like serine protease from the common carp","authors":"Miki Nakao,&nbsp;Kazunori Osaka,&nbsp;Yoko Kato,&nbsp;Tomoki Yano","doi":"10.1016/S0162-3109(00)80021-1","DOIUrl":"10.1016/S0162-3109(00)80021-1","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"49 1","pages":"Page 11"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0162-3109(00)80021-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79709560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Two divergent C4 isotypes of the common carp 鲤鱼两种不同的C4同型
Immunopharmacology Pub Date : 2000-08-01 Epub Date: 2002-07-10 DOI: 10.1016/S0162-3109(00)80023-5
Miki Nakao, Junichi Mutsuro, Noriyuki Tanaka, Satoru-Totsuka, Yoko Kato, Kazuhiro Fujiki, Tomiki Yano
{"title":"Two divergent C4 isotypes of the common carp","authors":"Miki Nakao,&nbsp;Junichi Mutsuro,&nbsp;Noriyuki Tanaka,&nbsp;Satoru-Totsuka,&nbsp;Yoko Kato,&nbsp;Kazuhiro Fujiki,&nbsp;Tomiki Yano","doi":"10.1016/S0162-3109(00)80023-5","DOIUrl":"10.1016/S0162-3109(00)80023-5","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"49 1","pages":"Page 12"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0162-3109(00)80023-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91163068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Expression of soluble and membrane-bound complement regulatory proteins by human hepatocytes 人肝细胞可溶性和膜结合补体调节蛋白的表达
Immunopharmacology Pub Date : 2000-08-01 DOI: 10.1016/S0162-3109(00)80175-7
H. Vogel, J. Halme, M. Kirschfink
{"title":"Expression of soluble and membrane-bound complement regulatory proteins by human hepatocytes","authors":"H. Vogel, J. Halme, M. Kirschfink","doi":"10.1016/S0162-3109(00)80175-7","DOIUrl":"https://doi.org/10.1016/S0162-3109(00)80175-7","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"26 1","pages":"63"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74557035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
The cleavage of two C1s subunits by a single active C1r reveals substantial flexibility of the C1s-C1r-C1r-C1s tetramer in the C1 complex 单个活性C1r对两个C1s亚基的切割揭示了C1复合物中C1s-C1r-C1r-C1s四聚体的实质性灵活性
Immunopharmacology Pub Date : 2000-08-01 DOI: 10.1016/S0162-3109(00)80261-1
P. Závodszky, Z. Lorincz, S. Cseh, J. Dobó, K. Szilágyi, G. Ambrus, P. Gál
{"title":"The cleavage of two C1s subunits by a single active C1r reveals substantial flexibility of the C1s-C1r-C1r-C1s tetramer in the C1 complex","authors":"P. Závodszky, Z. Lorincz, S. Cseh, J. Dobó, K. Szilágyi, G. Ambrus, P. Gál","doi":"10.1016/S0162-3109(00)80261-1","DOIUrl":"https://doi.org/10.1016/S0162-3109(00)80261-1","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"94 1","pages":"89"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77272764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Tissue distribution of mouse CD59 analyzed using a novel rat anti-mouse CD59 monoclonal antibody 利用一种新型大鼠抗小鼠CD59单克隆抗体分析小鼠CD59的组织分布
Immunopharmacology Pub Date : 2000-08-01 DOI: 10.1016/S0162-3109(00)80274-X
S. Hanna, C. Harris, B. Morgan
{"title":"Tissue distribution of mouse CD59 analyzed using a novel rat anti-mouse CD59 monoclonal antibody","authors":"S. Hanna, C. Harris, B. Morgan","doi":"10.1016/S0162-3109(00)80274-X","DOIUrl":"https://doi.org/10.1016/S0162-3109(00)80274-X","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"9 1","pages":"92"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81728840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Soluble complement receptor (sCR1) 1 rescues rats from lethal shock induced by priming of sublethal dose of lipopolysaccharide (LPS) and anti-Crry antibodies 可溶性补体受体(sCR1) 1可拯救亚致死剂量脂多糖(LPS)和抗crry抗体引发的致死性休克大鼠
Immunopharmacology Pub Date : 2000-08-01 DOI: 10.1016/S0162-3109(00)80177-0
M. Mizuno, K. Nishikawa, N. Okada, H. Okada, S. Matsuo
{"title":"Soluble complement receptor (sCR1) 1 rescues rats from lethal shock induced by priming of sublethal dose of lipopolysaccharide (LPS) and anti-Crry antibodies","authors":"M. Mizuno, K. Nishikawa, N. Okada, H. Okada, S. Matsuo","doi":"10.1016/S0162-3109(00)80177-0","DOIUrl":"https://doi.org/10.1016/S0162-3109(00)80177-0","url":null,"abstract":"","PeriodicalId":13327,"journal":{"name":"Immunopharmacology","volume":"16 1","pages":"63"},"PeriodicalIF":0.0,"publicationDate":"2000-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85091134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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