Special journal of the Medical Academy and other Life Sciences最新文献

{"title":"Lipid Therapy for Dyslipidemic Disorders Activates 21st Century Nano Antioxidant Hydrogen as a Potential Anti-COVID-19 Agent: Review","authors":"I. Vasilieva, Maria Vasilieva, I. Vasiliev","doi":"10.58676/sjmas.v1i7.41","DOIUrl":"https://doi.org/10.58676/sjmas.v1i7.41","url":null,"abstract":"According to the World Health Organization (WHO), coronavirus infection (COVID-19, (COronaVIrus Disease 2019) is an infectious disease caused by the SARS-CoV-2 virus [1]. SARS-CoV-2 virus, Severe Acute Respiratory Syndrome-related coronavirus 2. Initially considered pulmonary - respiratory pathology, then it turned out to be poly-systemic, with multi-inflammation of many other organs, and central nervous system. Multisystem inflammatory syndrome in adults (MIS-A) [2], SARS-CoV-2 liver infection [3]. In pediatrics Multisystem inflammatory syndrome in children (MIS-C) or PMIS-TS (Pediatric MIS temporarily associated with SARS-CoV-2 infection) [4,5], SARS-COV-2/ COVID-19 in children induce Kawasaki-Like Disease [6]. Neurological manifestations [7], recurrence of COVID-19 infection with meningitis without pulmonary involvement [8]. Brain damage in COVID is primarily neurological, as a material signaling pathway of inflammatory COVID-infection of cerebral vessels. This is important, from the release of these patients, from additional stress, suffering, stigmatization in society, their isolation, intimidation, coercion (bullying) with violation and restriction of their rights. Since, concomitantly with inflammatory lesions of many organs, cognitive deficits are a component of the post-acute consequences of COVID-19 (PASC), where the role of the kynurenine pathway is significant with temporary cognitive impairment [9]. The main pathway for the breakdown of tryptophan is an amino acid, without which the synthesis of serotonin is impossible, which controls the cycles of sleep and wakefulness, which is the precursor of the sleep hormone melatonin In patients with COVID-19, an imbalance of T-helpers 1 and 2 leads to a cytokine storm that can contribute to myocardial damage [10]. MIS is conditioned caused by immunocompromising (IC) CHAOS - [C]ardiovascular Compromise: shock; [H]omeostasis; [A]poptosis; [O]rgan Dysfunction; [S]uppression of the Immune System with the development of Systemic inflammatory response syndrome (SIRS) and Multiple Organ Dysfunction Syndrome (MODS) [11,12]. With pronounced multiple and other symptoms: Electro - Ion Membrane Distress Syndrome (Syndrome Maria & Irina Vasilieva) [13,14] with membrane manifestations of electrical storm or electromembrane paralysis; Capillary Leak Syndrome; Microcirculatory-Mitochondrial Distress Syndrom [15,16]. Also described: Overlap mechanisms of transient global amnesia and COVID-19 infection [17]; Hypokalemia-stroke mimic [18]; Differential diagnosis of cacosmia and dysgeusia in COVID-19 pandemic [19].","PeriodicalId":132909,"journal":{"name":"Special journal of the Medical Academy and other Life Sciences","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133244868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of association between childhood overweight/obesity with screen time, sedentary life style and low levels of physical activity","authors":"Hemanthi Darshana Kumari Ekanayake, Dr.Ghassan Salibi, N. Tzenios","doi":"10.58676/sjmas.v1i6.40","DOIUrl":"https://doi.org/10.58676/sjmas.v1i6.40","url":null,"abstract":"The escalating prevalence of childhood obesity, affecting nearly 40 million children under five globally, has become a pressing public health concern. The high incidence of obesity in this population can be attributed to numerous factors, such as unhealthy eating habits, lack of physical activity, sedentary lifestyle, and increased screen time, which were exacerbated by worldwide lockdowns during the Covid-19 pandemic. These factors, together with obesity, can potentially predispose these children to non-communicable diseases such as coronary artery disease, type 2 diabetes, and cancer, thereby increasing morbidity and mortality rates. This capstone project aims to globally assess the prevalence of obesity or overweight status in children, establish a relationship between screen usage, physical activity levels, and sedentary behavior, and examine the impact of Covid-19 lockdowns on these parameters. The study methodology includes a comprehensive literature review and data collection from global studies on childhood obesity. Findings from this study could be instrumental in identifying risk factors and developing interventions to mitigate the rising rates of childhood obesity, ultimately supporting the WHO's goal of \"no rise in childhood overweight by 2025\". Additionally, the study would provide valuable recommendations to decrease sedentary behavior in children and increase physical activity levels, promoting healthier lifestyle choices in children.","PeriodicalId":132909,"journal":{"name":"Special journal of the Medical Academy and other Life Sciences","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116110437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"OMPARISON OF EFFICACY AMONG DIFFERENT THERAPEUTIC APPROACHES IN ECTOPIC PREGNANCY","authors":"Lorenzo Ludwig, Poh Omasyarifa Binti Jamal","doi":"10.58676/sjmas.v1i6.38","DOIUrl":"https://doi.org/10.58676/sjmas.v1i6.38","url":null,"abstract":"Ectopic pregnancy (EP) occurs when the fertilized ovum implants outside the endometrial cavity, with an incidence of 1% of all pregnancies [2,5,8]. Frequently, the products of conception grow in the fallopian tube. Other implantation sites are the ovaries or the cervix. The vast majority of EP cases affect the fallopian tube, with 70-76 % of these tubal EPs occurring in the ampullary portion, 11-16 % in the isthmic portion and about 2-10 % of in the fallopian tube’s fimbrial end. Affected patients may face significant morbidity or even mortality. Prior tubal surgery or a prior tubal pregnancy are the most important risk factors for tubal pregnancy. Women with an active or prior ascending infection with Chlamydia trachomatis or Neisseria gonorrhoeae are at an elevated risk of extrauterine pregnancy. Extrauterine pregnancy may be wholly asymptomatic (intact tubal pregnancy),or it may present with pelvic pain that is worse on one side (tubal abortion) or with severe hemorrhagic shock (tubal rupture). Extrauterine pregnancies are most diagnosed in the 6th through 9th week of gestation . Most patients present with nonspecific complaints. The symptom triad of mild vaginal spotting in the first trimester, aching pelvic pain, and secondary amenorrhea may indicate extrauterine pregnancy but can also arise in an intact intrauterine pregnancy or because of early miscarriage. Further suggestive manifestations include abdominal pain radiating to the shoulder(s), abdominal guarding or an acute abdomen, pain on the displacement of the vaginal portion of the cervix, hemorrhagic shock/hemodynamic instability (dyspnea, hypotension, tachycardia), and syncope. During the last decades, transvaginal ultrasound and beta-human chorionic gonadotropin (beta-HCG) levels became part of the clinical routine leading to the timely detection of ectopic pregnancies and better patient outcomes.","PeriodicalId":132909,"journal":{"name":"Special journal of the Medical Academy and other Life Sciences","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130642587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modern approaches of rehabilitation in COPD patients","authors":"Shivanshu Sharma, Dr.Ghassan Salibi, N. Tzenios","doi":"10.58676/sjmas.v1i6.39","DOIUrl":"https://doi.org/10.58676/sjmas.v1i6.39","url":null,"abstract":"Chronic Obstructive Pulmonary Disease (COPD) presents a significant challenge to public health, impairing the quality of life for affected individuals. Traditionally, the management of COPD primarily involved pharmacological interventions and symptom management, but a shift towards comprehensive rehabilitation programs has been observed in recent times. This study focuses on exploring these modern approaches to COPD rehabilitation, including exercise training, education, psychosocial support, and self-management strategies. By emphasizing patient-centered and multidisciplinary methodologies, modern rehabilitation approaches aim to address the individual needs of COPD patients. Previous studies affirm the positive impacts of these comprehensive programs, including improved exercise capacity, reduced symptoms, and enhanced overall well-being. This current investigation aims to further analyze the effects of various pulmonary rehabilitation methods on COPD management within a modern medical context. By critically evaluating literature and research databases like SCOPUS, PubMed, SciELO, Google Scholar, and Cochrane Library, this study seeks to provide unique insights into the efficacy and benefits of pulmonary rehabilitation for COPD patients. The implications of this research could contribute significantly to evidence-based practices, assisting healthcare professionals in optimizing the selection and implementation of pulmonary rehabilitation interventions for improved patient outcomes.","PeriodicalId":132909,"journal":{"name":"Special journal of the Medical Academy and other Life Sciences","volume":"193 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114748429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uncovering the Neglected Meal: Medical Students in Sri Lanka and Skipping Meals","authors":"N. Tzenios, Ghassan Salibi, Roshelle Nirusha Hemantraj","doi":"10.58676/sjmas.v1i5.36","DOIUrl":"https://doi.org/10.58676/sjmas.v1i5.36","url":null,"abstract":"Background: To figure out why a lot of students who are at risk for food insecurity consistently skip meals in university, this research follows the daily food travels of those students. to find the reasons for skipping meals. Purpose: The aim of this study is to analyse how a daily routine of a medical student of Sri Lanka, affects their eating patterns. Design/ methodology/Approach- A Survey study was implemented using convenient sampling technique where 170 questionnaires were distributed through google forms from which 148 responses were obtained. To test the hypothesis, Cronbach alpha and correlation analysis IBM SPSS 21.0 package was utilized. Findings- This article analyses how a daily routine of a medical student of Sri Lanka affects their eating patterns. The findings demonstrate that university lecture schedules, stress, depression, and loneliness are making students skip at least one of the main meals daily. The authors’ research shows that frequently skipped meals of the students is breakfast. Conclusion- This research provides information to medical university administrations, families, and friends. Therefore, university administration, families and other students may take required decision regarding the quality of life of medical students based on their university lecture schedules, stress, depression, and loneliness. This research study contributes significantly to this aspect telling universities and families the substantial requirement for stress and time management these days to generate a healthy eating pattern.","PeriodicalId":132909,"journal":{"name":"Special journal of the Medical Academy and other Life Sciences","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123321075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of AIDS in West Africa: The Nigerian Society","authors":"N. Tzenios, Ghassan Salibi, Fabiyi Tolani Fathia","doi":"10.58676/sjmas.v1i5.35","DOIUrl":"https://doi.org/10.58676/sjmas.v1i5.35","url":null,"abstract":"Nigeria has experienced a tremendous impact from HIV/AIDS on both a personal and societal level. The report presents a comprehensive problem overview referencing existing research, relevant literature, and expert insights. Due to HIV/AIDS, the Nigerian healthcare industry has experienced significant difficulties. With rising demand for testing, counseling, anti-retroviral medication (ART), and supportive care, the disease has strained healthcare resources. The disease has decreased production and resulted in a loss of human capital. The workforce has been impacted, which has reduced output across several industries, including agriculture. Concerns about the disease's prevalence have hurt foreign investment, preventing economic expansion and employment development. HIV/AIDS has impacted communities' social dynamics. Discrimination and stigma still exist, putting obstacles in support, treatment, and testing. The disease has put a strain on social welfare institutions, needing assistance for those who are afflicted and their families. Fighting the epidemic and lessening its effects require coordinated efforts from the government, civil society organizations, healthcare providers, and communities.","PeriodicalId":132909,"journal":{"name":"Special journal of the Medical Academy and other Life Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128578009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The PHYSIOLOGY OF MENSTRUAL PAIN AND THE EFFECTIVENESS OF TECHNOLOGY-BASED PAIN MANAGEMENT TECHNIQUES","authors":"Kshitij Prakash Korekar, Poh Omasyarifa Binti Jamal, Khuraseva Anna Borisovna","doi":"10.58676/sjmas.v1i5.32","DOIUrl":"https://doi.org/10.58676/sjmas.v1i5.32","url":null,"abstract":"Dysmenorrhea or menstrual pain significantly affects the quality of life for many women, necessitating effective and non-invasive pain management strategies. This study systematically reviewed existing literature on the physiological causes of menstrual pain and the effectiveness of technology-based pain relief techniques. The review shows that menstrual pain is mainly regulated by the hypothalamus-pituitary-ovary axis, with prostaglandins and inflammatory cytokines playing key roles. Also, stress and anxiety can amplify menstrual discomfort. It also uncovers several technology-based interventions for effective pain management, including Transcutaneous Electrical Nerve Stimulation (TENS), heat therapy, mobile apps, virtual reality (VR), and wearable tech. However, potential risks and limitations of these interventions, such as overreliance, data security, limited accessibility, varying effectiveness, cost, user acceptance, and lack of human contact, were also identified. Despite these limitations, technology-based pain management techniques represent promising non-invasive alternatives for managing menstrual discomfort. Additional high-quality research is needed to further validate the efficacy of these approaches and address potential risks.","PeriodicalId":132909,"journal":{"name":"Special journal of the Medical Academy and other Life Sciences","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127675074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Finances of healthcare around the globe and its outcomes","authors":"Kshitij Prakash Korekar, Dr.Ghassan Salibi","doi":"10.58676/sjmas.v1i5.31","DOIUrl":"https://doi.org/10.58676/sjmas.v1i5.31","url":null,"abstract":"The research aim of this article is to comprehend how healthcare systems are financed globally and how that affects patient outcomes. The project's objective is to explore various financial models used to cover healthcare services in different countries and the effects these models have on accessibility and care quality. Analyzing numerous research materials for this study will involve reviewing financial reports, governmental legislation, academic studies, and statistical data. The project's goals include analyzing health funding models in-depth, connecting health outcomes to financial models, and determining variables that influence financial success. The project's objectives are to develop a knowledge base that stakeholders may utilize to better understand the global healthcare funding system and to provide recommendations for enhancing healthcare funding systems. The essay also studies healthcare spending in various nations in 2019, 2020, and 2021, noting the variations in healthcare coverage between nations.","PeriodicalId":132909,"journal":{"name":"Special journal of the Medical Academy and other Life Sciences","volume":"83 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115753373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GLOBAL SYSTEMATIC REVIEW AND META-ANALYSIS OF FOETAL AND MATERNAL OUTCOMES IN PREGNANT WOMEN INFECTED WITH COVID-19","authors":"Poh Omasyarifa Binti Jamal, P. Puneet","doi":"10.58676/sjmas.v1i4.28","DOIUrl":"https://doi.org/10.58676/sjmas.v1i4.28","url":null,"abstract":"This study aimed to systematically review the effects of COVID-19 infection on pregnant women and their neonatal outcomes in eight countries: UK, USA, China, France, India, Russia, Italy, and Iran. Data from various registries worldwide were analyzed, focusing on preterm births, maternal and neonatal mortality rates, and mode of delivery. The results showed that all countries experienced a significant increase in preterm birth rates among COVID-19-infected pregnant women compared to non-infected pregnant women. No significant difference was observed in maternal mortality rates across the countries, but India had the highest neonatal mortality rate. The rate of vertical transmission from infected mothers in the third trimester to their infants was estimated at 3.2%. In conclusion, COVID-19 has the most significant impact on the increase of preterm birth rates, with India experiencing the highest neonatal mortality rate compared to the other country.","PeriodicalId":132909,"journal":{"name":"Special journal of the Medical Academy and other Life Sciences","volume":"1079 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116027605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE EXISTENCE OF HPV VACCINATION PROGRAM AND ITS RELEVANCE IN THE PREVENTION OF CERVICAL CANCER IN RUSSIAN FEDERATION, BRAZIL, INDIA, JAPAN, CHINA, MALAYSIA, NIGERIA AND SWITZERLAND Authors","authors":"Poh Omasyarifa Binti Jamal, Nascimento dos Santos","doi":"10.58676/sjmas.v1i4.29","DOIUrl":"https://doi.org/10.58676/sjmas.v1i4.29","url":null,"abstract":"Background: Cervical cancer remains a significant health concern globally. The introduction of the Human Papilloma Virus (HPV) vaccine and the Papanicolaou smear (Pap smear) screening test have contributed to reducing cervical cancer morbidity and mortality. This study aims to evaluate the impact of these preventive measures on cervical cancer mortality rates in eight countries: Russia, Nigeria, India, China, Japan, Switzerland, Brazil, and Malaysia. Methods: We conducted a systematic review and meta-analysis using data from the World Health Organization (WHO), United Nations, World Bank, International Agency for Research on Cancer (IARC), and other sources for 2019 and 2020. Mortality rates, HPV vaccination programs, screening usage, and cervical cancer risk among females aged 0-74 years were analyzed and compared. Results: China reported the highest number of cervical cancer deaths (51,600), but Brazil had the highest mortality rate (1.56%). The lowest mortality rate was observed in Switzerland (0.30%). HPV vaccination was included in the national schedule for Japan, Switzerland, Brazil, and Malaysia. Screening for cervical cancer was implemented in all eight countries, with Russia and Switzerland having the highest frequency (8:10 each) and India having the least (<1:10). Conclusion: The combination of HPV vaccination programs and active screening is the most effective measure for preventing cervical cancer mortality, as demonstrated by Switzerland. However, the importance of screening cannot be understated, as seen in Russia, where screening alone plays a significant role in cervical cancer prevention. Further efforts should focus on integrating both preventive strategies to reduce the global burden of cervical cancer.","PeriodicalId":132909,"journal":{"name":"Special journal of the Medical Academy and other Life Sciences","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130757635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}