Indian Journal of Paediatric Dermatology最新文献_第7页

Severe cicatricial ectropion and lagophthalmos secondary to herpes zoster ophthalmicus in an immunocompetent child 免疫功能正常儿童继发于眼带状疱疹的严重瘢痕性外翻和眼lagopmos

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Indian Journal of Paediatric Dermatology Pub Date : 2023-01-01 DOI: 10.4103/ijpd.ijpd_42_22

D. Gupta, Revathi Tatavarthi, P. Shilpashree, N. M. Madan Mohan

引用次数: 0

Pediatric Psoriasis: A Closer View on Clinical Presentations 小儿牛皮癣:近距离观察临床表现

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Indian Journal of Paediatric Dermatology Pub Date : 2023-01-01 DOI: 10.4103/ijpd.ijpd_15_22

Dooha K. Alhamdi, Khalil Alhamdi

引用次数: 0

Hereditary sensory and autonomic neuropathy type II in two brothers, a close differential of leprosy 二兄弟遗传性感觉和自主神经病变II型，麻风病的密切区别

Indian Journal of Paediatric Dermatology Pub Date : 2023-01-01 DOI: 10.4103/ijpd.ijpd_34_22

Parul Verma, Sonal Sachan, Nishant Verma, Swastika Suvirya, Prakriti Shukla

引用次数: 0

Childhood Lupus Vulgaris after Bacillus Calmette–Guérin Vaccine 卡介苗接种后的儿童寻常性狼疮

Indian Journal of Paediatric Dermatology Pub Date : 2023-01-01 DOI: 10.4103/ijpd.ijpd_19_23

Sarah Hamdy Soliman, Amany El Agamy El-Samadony, Ghada F. Rezk Hassan, Rania Ahmed El-Tatawy, Nesrin Sabry Gomaa

引用次数: 0

Dupilumab as a Combination Therapy to Oral Systemic Immunomodulators for Moderate-to-Severe Atopic Dermatitis for Skin of Color Children in Resource-Limited Setting: A Case Series 杜匹单抗联合口服全身免疫调节剂治疗资源有限的有色儿童中重度特应性皮炎:一个病例系列

Indian Journal of Paediatric Dermatology Pub Date : 2023-01-01 DOI: 10.4103/ijpd.ijpd_94_22

Siti Nuraihan, MN Azmi, Sabeera Begum, Kin Fon Leong

{"title":"Dupilumab as a Combination Therapy to Oral Systemic Immunomodulators for Moderate-to-Severe Atopic Dermatitis for Skin of Color Children in Resource-Limited Setting: A Case Series","authors":"Siti Nuraihan, MN Azmi, Sabeera Begum, Kin Fon Leong","doi":"10.4103/ijpd.ijpd_94_22","DOIUrl":"https://doi.org/10.4103/ijpd.ijpd_94_22","url":null,"abstract":"Abstract Subcutaneous dupilumab, with or without topical therapy, is clinically proven to treat children with moderate-to-severe atopic dermatitis (AD). However, this well-researched biologic for AD in children is still among the most expensive medication in the world and not widely available in resource-poor areas. We share our experience managing four children with severe AD, aged 3 to 11, who poorly responded to oral systemic immunomodulators but successfully achieved rapid clinical remission when combined with subcutaneous dupilumab. No loading doses were administered to patients in this case series, and the maintenance dosages used were lower than the manufacturer’s recommendations. This case series illustrates that oral immunomodulators in combination with subcutaneous dupilumab therapy are efficacious, safe, tolerable, and cost-effective for children with moderate-to-severe AD. This treatment strategy can be considered an alternative for children with AD recalcitrant to other available treatment options, especially when AD management is challenging in limited resource settings.","PeriodicalId":13275,"journal":{"name":"Indian Journal of Paediatric Dermatology","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136258009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Skin as a window to diagnose inborn errors of metabolism 皮肤是诊断先天代谢缺陷的窗口

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Indian Journal of Paediatric Dermatology Pub Date : 2023-01-01 DOI: 10.4103/ijpd.ijpd_100_22

D. Sathishkumar, A. Somasundaram, M. Chiramel, S. Korula

引用次数: 0

Eczema coxsackium: An unusual manifestation of hand, foot, and mouth disease 柯萨奇湿疹:手、足、口疾病的一种不寻常的表现

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Indian Journal of Paediatric Dermatology Pub Date : 2023-01-01 DOI: 10.4103/ijpd.ijpd_33_22

M. Munisamy, C. Indra, J. Mathews, Rajendra Devanda

引用次数: 0

Efficacy and Safety of a Skin Healing Cream in Mild-to-Moderate Eczema in a Mixed Population Including Infants: An Open-label, Single-arm Study 一种皮肤愈合霜在包括婴儿在内的混合人群中治疗轻中度湿疹的疗效和安全性:一项开放标签单臂研究

Indian Journal of Paediatric Dermatology Pub Date : 2023-01-01 DOI: 10.4103/ijpd.ijpd_5_23

Shilpa Dhar, Trupti Patel, Arohi Bapna, Govindarajan Raghavan

{"title":"Efficacy and Safety of a Skin Healing Cream in Mild-to-Moderate Eczema in a Mixed Population Including Infants: An Open-label, Single-arm Study","authors":"Shilpa Dhar, Trupti Patel, Arohi Bapna, Govindarajan Raghavan","doi":"10.4103/ijpd.ijpd_5_23","DOIUrl":"https://doi.org/10.4103/ijpd.ijpd_5_23","url":null,"abstract":"Abstract Introduction: Atopic dermatitis is an inflammatory skin condition that begins in infancy, characterized by extreme skin dryness, excoriations, and erythema. A completely natural product with plant extracts and vegetable oils was developed to manage eczema and associated conditions in a mixed population including infants. Materials and Methods: An open-label, single-arm, single-center study was conducted to evaluate the safety and efficacy of the test product on eczema severity. A total of 58 subjects, including infants, children, and adults aged 0 months to 60 years, diagnosed with mild-to-moderate eczema, were included. The subjects applied a small amount of product on the affected area twice daily for 14 days. Three-Item Severity (TIS) score, Eczema Area and Severity Index (EASI) change, and symptomatic relief were assessed at various time points. Results: The TIS score in children significantly reduced from baseline at 24 h (12.22%), day 7 (52.26%), and day 14 (79.74%), (all P <0.0001). Similarly, a statistically significant reduction in EASI was observed in adults at day 7 (13.68%) and day 14 (30.87%) (all P < 0.0001), which continued to offer relief throughout the study duration. Irritation significantly decreased from baseline throughout the study duration to day 14 (75.17%) ( P < 0.0001). A significant reduction in other symptoms including dryness, itching, rashes, and edema was also seen from day 7 to day 14 ( P < 0.0001). Conclusion: The test product was found to be safe and effective in reducing eczema severity and associated conditions in infants and adults. It promotes the development of healthy neonatal skin and hence can be considered as a skin-healing cream for infants.","PeriodicalId":13275,"journal":{"name":"Indian Journal of Paediatric Dermatology","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136257701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A clinical study of dermatoses in neonatal intensive care unit in a tertiary health-care center 某三级保健中心新生儿重症监护病房皮肤病的临床研究

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Indian Journal of Paediatric Dermatology Pub Date : 2023-01-01 DOI: 10.4103/ijpd.ijpd_7_22

KB Kavya, S. Reddy, G. Guruprasad

引用次数: 0

A challenging case of recalcitrant Hyper-IgE syndrome successfully treated with omalizumab 奥马珠单抗成功治疗顽固性高IgE综合征的一个具有挑战性的病例

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Indian Journal of Paediatric Dermatology Pub Date : 2022-10-01 DOI: 10.4103/ijpd.ijpd_36_22

Rashid Shahid, S. Pradhan, Suvesh Singh

引用次数: 0