{"title":"Investigation of the Impact of Low–Dose Computed Tomography (LDCT) Screening for Primary Lung Cancer (PLC) on the Risk of Developing Brain Metastasis (BM) after Primary Lung Cancer (PLC) Diagnosis","authors":"Ricardo Gobato, Abhijit Mitra","doi":"10.36811/ojrmi.2021.110039","DOIUrl":"https://doi.org/10.36811/ojrmi.2021.110039","url":null,"abstract":"Using samples of small cell lung tumors, a research team led by biologist Dr. Raymond discovered two new ways to induce tumor cell death. By activating ferroptosis, one of two subtypes of tumor cells can be targeted: first, iron-dependent cell death due to oxidative stress, and second, oxidative stress. Therefore, cell death can also be induced in a different way. Both types of cell death must be caused by drugs at the same time to eliminate the majority of the tumor mass.\u0000\u0000Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management","PeriodicalId":132118,"journal":{"name":"Open Journal of Radiology and Medical Imaging","volume":"275 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116553354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Importance of the oblique reconstruction of CT scan MPR formatting: A pictorial review","authors":"A. Alahmari","doi":"10.36811/ojrmi.2021.110041","DOIUrl":"https://doi.org/10.36811/ojrmi.2021.110041","url":null,"abstract":"A common mistake among radiographers is reconstructing a CT scan and taking table top as a reference for the reconstruction. This paper, will mention in details what are some examples for oblique reconstruction with illustrated images.\u0000\u0000Keywords: Oblique Reconstruction; Computed Tomography; Multi-Planer Reformat","PeriodicalId":132118,"journal":{"name":"Open Journal of Radiology and Medical Imaging","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114722965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study of Tumor Cells in the G0 or G1 Nerve Growth State","authors":"Ricardo Gobato, Abhijit Mitra","doi":"10.36811/ojrmi.2021.110025","DOIUrl":"https://doi.org/10.36811/ojrmi.2021.110025","url":null,"abstract":"The cell cycle of such a subject has been thoroughly studied, yet here we are examining for the second time that we have entered a new phase; Biology always has new insights to show us. This data was amazing. This map is based on this beautiful circular pattern that we have identified as all the different stages of the cell cycle. Have a disease. When Placer and colleagues used the ccAF tool to analyze cell data for glioma tumors, we found that tumor cells were often in the G0 or G1 nerve growth state. With tumor aggression, fewer cells remain at rest in the G0 nerve state. This means that more cells are growing and growing in the tumor.\u0000\u0000Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management","PeriodicalId":132118,"journal":{"name":"Open Journal of Radiology and Medical Imaging","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128315444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Delivering Lung Cancer Care During the COVID–19 Pandemic","authors":"Ricardo Gobato, Abhijit Mitra","doi":"10.36811/ojrmi.2021.110035","DOIUrl":"https://doi.org/10.36811/ojrmi.2021.110035","url":null,"abstract":"Early and timely diagnosis of any disease, especially cancer; Increases the chances of treatment and recovery; Therefore, it is better to be aware of the symptoms of lung cancer in the continuation of this article. It is advisable to first get acquainted with the causes of lung cancer so that we can assess our situation. The most important causes of lung cancer are smoking and other tobacco products, genetic mutations and family history. Second- and third-hand cigarette smoke and environmental pollutants such as air pollution also play a role in the development of this cancer. Of course, the role of colorless gas and the smell of radon and occupational exposure to compounds such as asbestos, arsenic and nickel should not be overlooked. Once we know the causes of lung cancer, we can look at its symptoms in our body. The most important symptoms of lung cancer are persistent cough, fatigue and lack of energy, and unexplained weight loss. Coughs such as coughing up blood and shortness of breath are other important symptoms of this cancer. Stomach, back, shoulder, and chest pain, as well as pain in the head, neck, and jaw, are other symptoms. In order to prevent lung cancer, special points should be considered, which we will mention in the following. The main advice is to avoid smoking and also not to be exposed to secondhand smoke; Therefore, avoid using any tobacco and quit if you smoke. People who are in work situations and exposure to things like asbestos should try to minimize this exposure and use breathing masks. Opening windows and covering cracks in walls and floors is important to reduce radon concentrations. It is recommended to eat more vegetables and fruits, especially cabbage, orange vegetables and garlic. It is important to note that awareness of the symptoms of the disease is very important for early diagnosis and thus increase the chances of treatment.\u0000\u0000Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management","PeriodicalId":132118,"journal":{"name":"Open Journal of Radiology and Medical Imaging","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115191192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Process of Converting Glucose to Energy, Single Endothelial Cells and Blood Vessel Cells","authors":"Ricardo Gobato, Abhijit Mitra","doi":"10.36811/ojrmi.2021.110026","DOIUrl":"https://doi.org/10.36811/ojrmi.2021.110026","url":null,"abstract":"Understanding cellular metabolism (how cells use energy) can be key in treating a wide range of diseases, including vascular disease and cancer. Although many techniques can measure these processes in tens of thousands of cells, researchers have not been able to measure them at the single-cell level. Researchers have used a genetically encoded biosensor with artificial intelligence to measure glycolysis. (Process of converting glucose to energy, single endothelial cells, blood vessel cells).\u0000\u0000Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management","PeriodicalId":132118,"journal":{"name":"Open Journal of Radiology and Medical Imaging","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116840469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role and Importance of Inflammasomes and Immune Pathways in Myeloid Malignancies, Particularly Myelodysplastic Syndromes (MDS)/Acute Myeloid Leukemia (AML) to Better Understand the Disease Pathophysiology and Decipher the Scope of Therapeutic Interventions","authors":"Ricardo Gobato, Abhijit Mitra","doi":"10.36811/ojrmi.2021.110040","DOIUrl":"https://doi.org/10.36811/ojrmi.2021.110040","url":null,"abstract":"Thanks to work by researchers at the California South University (CSU) Cancer Research Institute (CRI), they may soon have new tools to treat melanoma and other cancers. In an article published last month, members of the Cancer Research Institute (CRI) introduced an intracellular complex. Involved in melanoma-mediated inflammation and leads to tumor growth and progression. The researchers found that by inhibiting NLRP3, they could reduce inflammation and tumor spread.\u0000\u0000Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management","PeriodicalId":132118,"journal":{"name":"Open Journal of Radiology and Medical Imaging","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129533400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnosis, Response Assessment and Treatment Outcomes in Acute Myeloid Leukemia (AML)","authors":"Alireza Heidari, Ricardo Gobato, Abhijit Mitra","doi":"10.36811/ojrmi.2021.110036","DOIUrl":"https://doi.org/10.36811/ojrmi.2021.110036","url":null,"abstract":"Leukemia occurs when a person's entire bone marrow tissue space is occupied by cancer cells or blasts that are young, dysfunctional, undifferentiated, and proliferating cells. In this situation, there is no space left for the bone marrow to be able to produce normal blood cells such as platelets, red and white blood cells. These patients suffer from severe bleeding due to decreased platelets or due to a decrease in white blood cells, which are often diagnosed with dangerous infections that cause death in these patients. The exact cause of leukemias is not yet known, but a number of factors have been identified that play a role in the development of these cancers, including high doses of radiation or atomic radiation, prolonged exposure to certain chemicals, and some Mentioned viruses and some genetic diseases such as Down syndrome or underlying diseases.\u0000\u0000Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management","PeriodicalId":132118,"journal":{"name":"Open Journal of Radiology and Medical Imaging","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131190871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Discovering and Engineering an Enzyme as Inhibitor for the Growth of Cancer Cells by Stimulating Proteins","authors":"Ricardo Gobato, Abhijit Mitra","doi":"10.36811/ojrmi.2021.110038","DOIUrl":"https://doi.org/10.36811/ojrmi.2021.110038","url":null,"abstract":"Researchers have discovered an enzyme that inhibits the growth of cancer cells by stimulating proteins. In this study, the ability of each human cell to divide into two parts is discussed. For each division, a cell must follow certain steps, most of which are amplified by proteins called cyclins.\u0000\u0000Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management","PeriodicalId":132118,"journal":{"name":"Open Journal of Radiology and Medical Imaging","volume":"158 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116497715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiation Therapy to the Whole Brain and Spine, Followed by an Extra Dose of Radiation to the Back of the Brain","authors":"Ricardo Gobato, Abhijit Mitra","doi":"10.36811/ojrmi.2021.110027","DOIUrl":"https://doi.org/10.36811/ojrmi.2021.110027","url":null,"abstract":"Medulloblastoma is a rare but devastating brain cancer in children. The cancer can spread through the spinal fluid and deposit elsewhere in the brain or spine. Radiation therapy to the whole brain and spine, followed by an extra dose of radiation to the back of the brain, prevented this spread and became the standard of care. However, radiation used to treat such tumors causes damage to the brain and impairs cognitive function. It affects, especially in young patients whose brains are growing.\u0000\u0000Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management","PeriodicalId":132118,"journal":{"name":"Open Journal of Radiology and Medical Imaging","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121035373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New Drug Sotorasib Reduces Tumor Size and Promises to Improve and Increase Survival in Patients with Lung Tumors Caused by Specific DNA Mutations","authors":"Ricardo Gobato, Abhijit Mitra","doi":"10.36811/ojrmi.2021.110031","DOIUrl":"https://doi.org/10.36811/ojrmi.2021.110031","url":null,"abstract":"According to the results of a global phase 2 clinical trial, the new drug stores reduce tumor size and promises to improve and increase survival in patients with lung tumors caused by specific DNA mutations. It is designed to counteract the effects of mutations that are seen in about 13% of patients with non-small cell lung adenocarcinoma (a common type of lung cancer). The Food and Drug Administration (FDA) on May 28 approved the drug as a targeted treatment for patients with small cell lung cancer whose tumors express a specific mutation called G12C in the KRAS gene. Small cell lung cancer accounts for more than 80% of lung cancers. More than 200,000 new cases of non-small cell lung cancer are diagnosed in the United States each year.\u0000\u0000Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management","PeriodicalId":132118,"journal":{"name":"Open Journal of Radiology and Medical Imaging","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129635732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}