IEEE Journal of Biomedical and Health Informatics最新文献_第5页

Innovative Dual-Decoupling CNN with Layer-wise Temporal-Spatial Attention for Sensor-Based Human Activity Recognition. 基于传感器的人类活动识别：创新的双解耦（Dual-Decoupling）CNN与分层时空关注（Layer-wise Temporal-Spatial Attention）。

IF 6.7 2区医学

IEEE Journal of Biomedical and Health Informatics Pub Date : 2024-10-30 DOI: 10.1109/JBHI.2024.3488528

Qi Teng, Wei Li, Guangwei Hu, Yuanyuan Shu, Yun Liu

{"title":"Innovative Dual-Decoupling CNN with Layer-wise Temporal-Spatial Attention for Sensor-Based Human Activity Recognition.","authors":"Qi Teng, Wei Li, Guangwei Hu, Yuanyuan Shu, Yun Liu","doi":"10.1109/JBHI.2024.3488528","DOIUrl":"https://doi.org/10.1109/JBHI.2024.3488528","url":null,"abstract":"Human Activity Recognition (HAR) is essential for monitoring and analyzing human behavior, particularly in health applications such as fall detection and chronic disease management. Traditional methods, even those incorporating attention mechanisms, often oversimplify the complex temporal and spatial dependencies in sensor data by processing features uniformly, leading to inadequate modeling of high-dimensional interactions. To address these limitations, we propose a novel framework: the Temporal-Spatial Feature Decoupling Unit with Layer-wise Training Convolutional Neural Network (CNN-TSFDU-LW). Our model enhances HAR accuracy by decoupling temporal and spatial dependencies, facilitating more precise feature extraction and reducing computational overhead. The TSFDU mechanism enables parallel processing of temporal and spatial features, thereby enriching the learned representations. Furthermore, layer-wise training with a local error function allows for independent updates of each CNN layer, reducing the number of parameters and improving memory efficiency without compromising performance. Experiments on four benchmark datasets (UCI-HAR, PAMAP2, UNIMIB-SHAR, and USC-HAD) demonstrate accuracy improvements ranging from 0.9% to 4.19% over state-of-the-art methods while simultaneously reducing computational complexity. Specifically, our framework achieves accuracy rates of 97.90% on UCI-HAR, 94.34% on PAMAP2, 78.90% on UNIMIB-SHAR, and 94.71% on USC-HAD, underscoring its effectiveness in complex HAR tasks. In conclusion, the CNN-TSFDU-LW framework represents a significant advancement in sensor-based HAR, delivering both improved accuracy and computational efficiency, with promising potential for enhancing health monitoring applications.","PeriodicalId":13073,"journal":{"name":"IEEE Journal of Biomedical and Health Informatics","volume":"PP ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multi-omics Graph Knowledge Representation for Pneumonia Prognostic Prediction. 用于肺炎预后预测的多组学图知识表示法

IF 6.7 2区医学

IEEE Journal of Biomedical and Health Informatics Pub Date : 2024-10-30 DOI: 10.1109/JBHI.2024.3488735

Wenyu Xing, Miao Li, Yiwen Liu, Xin Liu, Yifang Li, Yanping Yang, Jing Bi, Jiangang Chen, Dongni Hou, Yuanlin Song, Dean Ta

{"title":"Multi-omics Graph Knowledge Representation for Pneumonia Prognostic Prediction.","authors":"Wenyu Xing, Miao Li, Yiwen Liu, Xin Liu, Yifang Li, Yanping Yang, Jing Bi, Jiangang Chen, Dongni Hou, Yuanlin Song, Dean Ta","doi":"10.1109/JBHI.2024.3488735","DOIUrl":"https://doi.org/10.1109/JBHI.2024.3488735","url":null,"abstract":"Early prognostic prediction is crucial for determining appropriate clinical interventions. Previous single-omics models had limitations, such as high contingency and overlooking complex physical conditions. In this paper, we introduced multi-omics graph knowledge representation to predict in-hospital outcomes for pneumonia patients. This method utilizes CT imaging and three non-imaging omics information, and explores a knowledge graph for modeling multi-omics relations to enhance the overall information representation. For imaging omics, a multichannel pyramidal recursive MLP and Longformer-based 3D deep learning module was developed to extract depth features in lung window, while radiomics features were simultaneously extracted in both lung and mediastinal windows. Non-imaging omics involved the adoption of laboratory, microbial, and clinical indices to complement the patient's physical condition. Following feature screening, the similarity fusion network and graph convolutional network (GCN) were employed to determine omics similarity and provide prognostic prediction. The results of comparative experiments and generalization validation demonstrat that the proposed multi-omics GCN-based prediction model has good robustness and outperformed previous single-type omics, classical machine learning, and previous deep learning methods. Thus, the proposed multi-omics graph knowledge representation model enhances early prognostic prediction performance in pneumonia, facilitating a comprehensive assessment of disease severity and timely intervention for high-risk patients.","PeriodicalId":13073,"journal":{"name":"IEEE Journal of Biomedical and Health Informatics","volume":"PP ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Automatic Identification of Facial Tics Using Selfie-Video. 利用自拍视频自动识别面部抽搐。

IF 6.7 2区医学

IEEE Journal of Biomedical and Health Informatics Pub Date : 2024-10-30 DOI: 10.1109/JBHI.2024.3488285

Yocheved Loewenstern, Noa Benaroya-Milshtein, Katya Belelovsky, Izhar Bar-Gad

{"title":"Automatic Identification of Facial Tics Using Selfie-Video.","authors":"Yocheved Loewenstern, Noa Benaroya-Milshtein, Katya Belelovsky, Izhar Bar-Gad","doi":"10.1109/JBHI.2024.3488285","DOIUrl":"https://doi.org/10.1109/JBHI.2024.3488285","url":null,"abstract":"The intrinsic nature of tic disorders, characterized by symptom variability and fluctuation, poses challenges in clinical evaluations. Currently, tic assessments predominantly rely on subjective questionnaires administered periodically during clinical visits, thus lacking continuous quantitative evaluation. This study aims to establish an automatic objective measure of tic expression in natural behavioral settings. A custom-developed smartphone application was used to record selfie-videos of children and adolescents with tic disorders exhibiting facial motor tics. Facial landmarks were utilized to extract tic-related features from video segments labeled as either \"tic\" or \"non-tic\". These features were then passed through a tandem of custom deep neural networks to learn spatial and temporal properties for tic classification of these segments according to their labels. The model achieved a mean accuracy of 95% when trained on data across all subjects, and consistently exceeded 90% accuracy in leave-one-session-out and leave-one-subject-out cross validation training schemes. This automatic tic identification measure may provide a valuable tool for clinicians in facilitating diagnosis, patient follow-up, and treatment efficacy evaluation. Combining this measure with standard smartphone technology has the potential to revolutionize large-scale clinical studies, thereby expediting the development and testing of novel interventions.","PeriodicalId":13073,"journal":{"name":"IEEE Journal of Biomedical and Health Informatics","volume":"PP ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Multimodal Consistency-Based Self-Supervised Contrastive Learning Framework for Automated Sleep Staging in Patients with Disorders of Consciousness. 基于多模态一致性的自监督对比学习框架，用于意识障碍患者的自动睡眠分期。

IF 6.7 2区医学

IEEE Journal of Biomedical and Health Informatics Pub Date : 2024-10-29 DOI: 10.1109/JBHI.2024.3487657

Jahui Pan, Yangzuyi Yu, Man Li, Wanxin Wei, Shuyu Chen, Heyi Zheng, Yanbin He, Yuanqing Li

{"title":"A Multimodal Consistency-Based Self-Supervised Contrastive Learning Framework for Automated Sleep Staging in Patients with Disorders of Consciousness.","authors":"Jahui Pan, Yangzuyi Yu, Man Li, Wanxin Wei, Shuyu Chen, Heyi Zheng, Yanbin He, Yuanqing Li","doi":"10.1109/JBHI.2024.3487657","DOIUrl":"https://doi.org/10.1109/JBHI.2024.3487657","url":null,"abstract":"Sleep is a fundamental human activity, and automated sleep staging holds considerable investigational potential. Despite numerous deep learning methods proposed for sleep staging that exhibit notable performance, several challenges remain unresolved, including inadequate representation and generalization capabilities, limitations in multimodal feature extraction, the scarcity of labeled data, and the restricted practical application for patients with disorder of consciousness (DOC). This paper proposes MultiConsSleepNet, a multimodal consistency-based sleep staging network. This network comprises a unimodal feature extractor and a multimodal consistency feature extractor, aiming to explore universal representations of electroencephalograms (EEGs) and electrooculograms (EOGs) and extract the consistency of intra- and intermodal features. Additionally, self-supervised contrastive learning strategies are designed for unimodal and multimodal consistency learning to address the current situation in clinical practice where it is difficult to obtain high-quality labeled data but has a huge amount of unlabeled data. It can effectively alleviate the model's dependence on labeled data, and improve the model's generalizability for effective migration to DOC patients. Experimental results on three publicly available datasets demonstrate that MultiConsSleepNet achieves state-of-the-art performance in sleep staging with limited labeled data and effectively utilizes unlabeled data, enhancing its practical applicability. Furthermore, the proposed model yields promising results on a self-collected DOC dataset, offering a novel perspective for sleep staging research in patients with DOC.","PeriodicalId":13073,"journal":{"name":"IEEE Journal of Biomedical and Health Informatics","volume":"PP ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel Digital Biomarkers for Fine Motor Skills Assessment in Psoriatic Arthritis: The DaktylAct Touch-based Serious Game Approach. 用于评估银屑病关节炎患者精细运动技能的新型数字生物标记物：DaktylAct 基于触摸的严肃游戏方法

IF 6.7 2区医学

IEEE Journal of Biomedical and Health Informatics Pub Date : 2024-10-29 DOI: 10.1109/JBHI.2024.3487785

Eleni Vasileiou, Sofia B Dias, Stelios Hadjidimitriou, Vasilis Charisis, Nikolaos Karagkiozidis, Stavros Malakoudis, Patty de Groot, Stelios Andreadis, Vassilis Tsekouras, Georgios Apostolidis, Anastasia Matonaki, Thanos G Stavropoulos, Leontios J Hadjileontiadis

{"title":"Novel Digital Biomarkers for Fine Motor Skills Assessment in Psoriatic Arthritis: The DaktylAct Touch-based Serious Game Approach.","authors":"Eleni Vasileiou, Sofia B Dias, Stelios Hadjidimitriou, Vasilis Charisis, Nikolaos Karagkiozidis, Stavros Malakoudis, Patty de Groot, Stelios Andreadis, Vassilis Tsekouras, Georgios Apostolidis, Anastasia Matonaki, Thanos G Stavropoulos, Leontios J Hadjileontiadis","doi":"10.1109/JBHI.2024.3487785","DOIUrl":"https://doi.org/10.1109/JBHI.2024.3487785","url":null,"abstract":"Psoriatic Arthritis (PsA) is a chronic, inflammatory disease affecting joints, substantially impacting patients' quality of life, with European guidelines for managing PsA emphasizing the importance of assessing hand function. Here, we present a set of novel digital biomarkers (dBMs) derived from a touchscreen-based serious game approach, DaktylAct, intended as a proxy, gamified, objective assessment of hand impairment, with emphasis on fine motor skills, caused by PsA. This is achieved by its design, where the user controls a cannon to aim at and hit targets using two finger pinch-in/out and wrist rotation gestures. In-game metrics (targets hit and score) and statistical features (mean, standard deviation) of gameplay actions (duration of gestures, applied pressure, and wrist rotation angle) produced during gameplay serve as informative dBMs. DaktylAct was tested on a cohort comprising 16 clinically verified PsA patients and nine healthy controls (HC). Correlation analysis demonstrated a positive correlation between average pinch-in duration and disease activity (DA) and a negative correlation between standard deviation of applied pressure during wrist rotation and joint inflammation. Logistic regression models achieved 83% and 91% classification performance discriminating HC from PsA patients with low DA (LDA) and PsA patients with and without joint inflammation, respectively. Results presented here are promising and create a proof-of-concept, paving the way for further validation in larger cohorts.","PeriodicalId":13073,"journal":{"name":"IEEE Journal of Biomedical and Health Informatics","volume":"PP ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Attention-based q-space Deep Learning Generalized for Accelerated Diffusion Magnetic Resonance Imaging. 基于注意力的 q 空间深度学习泛化用于加速扩散磁共振成像。

IF 6.7 2区医学

IEEE Journal of Biomedical and Health Informatics Pub Date : 2024-10-29 DOI: 10.1109/JBHI.2024.3487755

Fangrong Zong, Zaimin Zhu, Jiayi Zhang, Xiaofeng Deng, Zhuangzhuang Li, Chuyang Ye, Yong Liu

{"title":"Attention-based q-space Deep Learning Generalized for Accelerated Diffusion Magnetic Resonance Imaging.","authors":"Fangrong Zong, Zaimin Zhu, Jiayi Zhang, Xiaofeng Deng, Zhuangzhuang Li, Chuyang Ye, Yong Liu","doi":"10.1109/JBHI.2024.3487755","DOIUrl":"https://doi.org/10.1109/JBHI.2024.3487755","url":null,"abstract":"Diffusion magnetic resonance imaging (dMRI) is a non-invasive method for capturing the microanatomical information of tissues by measuring the diffusion weighted signals along multiple directions, which is widely used in the quantification of microstructures. Obtaining microscopic parameters requires dense sampling in the q space, leading to significant time consumption. The most popular approach to accelerating dMRI acquisition is to undersample the q-space data, along with applying deep learning methods to reconstruct quantitative diffusion parameters. However, the reliance on a predetermined q-space sampling strategy often constrains traditional deep learning-based reconstructions. The present study proposed a novel deep learning model, named attention-based q-space deep learning (aqDL), to implement the reconstruction with variable q-space sampling strategies. The aqDL maps dMRI data from different scanning strategies onto a common feature space by using a series of Transformer encoders. The latent features are employed to reconstruct dMRI parameters via a multilayer perceptron. The performance of the aqDL model was assessed utilizing the Human Connectome Project datasets at varying undersampling numbers. To validate its generalizability, the model was further tested on two additional independent datasets. Our results showed that aqDL consistently achieves the highest reconstruction accuracy at various undersampling numbers, regardless of whether variable or predetermined q-space scanning strategies are employed. These findings suggest that aqDL has the potential to be used on general clinical dMRI datasets.","PeriodicalId":13073,"journal":{"name":"IEEE Journal of Biomedical and Health Informatics","volume":"PP ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Avatar-Based Picture Exchange Communication System Enhancing Joint Attention Training for Children With Autism. 基于阿凡达的图片交换交流系统加强自闭症儿童的联合注意力训练

IF 6.7 2区医学

IEEE Journal of Biomedical and Health Informatics Pub Date : 2024-10-29 DOI: 10.1109/JBHI.2024.3487589

Yongjun Ren, Runze Liu, Huinan Sang, Xiaofeng Yu

{"title":"Avatar-Based Picture Exchange Communication System Enhancing Joint Attention Training for Children With Autism.","authors":"Yongjun Ren, Runze Liu, Huinan Sang, Xiaofeng Yu","doi":"10.1109/JBHI.2024.3487589","DOIUrl":"https://doi.org/10.1109/JBHI.2024.3487589","url":null,"abstract":"Children with Autism Spectrum Disorder (ASD) often struggle with social communication and feel anxious in interactive situations. The Picture Exchange Communication System (PECS) is commonly used to enhance basic communication skills in children with ASD, but it falls short in reducing social anxiety during therapist interactions and in keeping children engaged. This paper proposes the use of virtual character technology alongside PECS training to address these issues. By integrating a virtual avatar, children's communication skills and ability to express needs can be gradually improved. This approach also reduces anxiety and enhances the interactivity and attractiveness of the training. After conducting a T-test, it was found that PECS assisted by a virtual avatar significantly improves children's focus on activities and enhances their behavioral responsiveness. To address the problem of poor accuracy of gaze estimation in unconstrained environments, this study further developed a visual feature-based gaze estimation algorithm, the three-channel gaze network (TCG-Net). It utilizes binocular images to refine the gaze direction and infer the primary focus from facial images. Our focus was on enhancing gaze tracking accuracy in natural environments, crucial for evaluating and improving Joint Attention (JA) in children during interactive processes.TCG-Net achieved an angular error of 4.0 on the MPIIGaze dataset, 5.0 on the EyeDiap dataset, and 6.8 on the RT-Gene dataset, confirming the effectiveness of our approach in improving gaze accuracy and the quality of social interactions.","PeriodicalId":13073,"journal":{"name":"IEEE Journal of Biomedical and Health Informatics","volume":"PP ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Nuclei-Focused Strategy for Automated Histopathology Grading of Renal Cell Carcinoma. 肾细胞癌组织病理学自动分级的核聚焦策略

IF 6.7 2区医学

IEEE Journal of Biomedical and Health Informatics Pub Date : 2024-10-28 DOI: 10.1109/JBHI.2024.3487004

Hyunjun Cho, Dongjin Shin, Kwang-Hyun Uhm, Sung-Jea Ko, Yosep Chong, Seung-Won Jung

{"title":"A Nuclei-Focused Strategy for Automated Histopathology Grading of Renal Cell Carcinoma.","authors":"Hyunjun Cho, Dongjin Shin, Kwang-Hyun Uhm, Sung-Jea Ko, Yosep Chong, Seung-Won Jung","doi":"10.1109/JBHI.2024.3487004","DOIUrl":"https://doi.org/10.1109/JBHI.2024.3487004","url":null,"abstract":"The rising incidence of kidney cancer underscores the need for precise and reproducible diagnostic methods. In particular, renal cell carcinoma (RCC), the most prevalent type of kidney cancer, requires accurate nuclear grading for better prognostic prediction. Recent advances in deep learning have facilitated end-to-end diagnostic methods using contextual features in histopathological images. However, most existing methods focus only on image-level features or lack an effective process for aggregating nuclei prediction results, limiting their diagnostic accuracy. In this paper, we introduce a novel framework, Nuclei feature Assisted Patch-level RCC grading (NuAP-RCC), that leverages nuclei-level features for enhanced patch-level RCC grading. Our approach employs a nuclei-level RCC grading network to extract grade-aware features, which serve as node features in a graph. These node features are aggregated using graph neural networks to capture the morphological characteristics and distributions of the nuclei. The aggregated features are then combined with global image-level features extracted by convolutional neural networks, resulting in a final feature for accurate RCC grading. In addition, we present a new dataset for patch-level RCC grading. Experimental results demonstrate the superior accuracy and generalizability of NuAP-RCC across datasets from different medical institutions, achieving a 6.15% improvement in accuracy over the second-best model on the USM-RCC dataset.","PeriodicalId":13073,"journal":{"name":"IEEE Journal of Biomedical and Health Informatics","volume":"PP ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142521773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An On-Board Executable Multi-Feature Transfer-Enhanced Fusion Model for Three-Lead EEG Sensor-Assisted Depression Diagnosis. 用于三导联脑电图传感器辅助抑郁症诊断的板载可执行多特征转移增强融合模型。

IF 6.7 2区医学

IEEE Journal of Biomedical and Health Informatics Pub Date : 2024-10-28 DOI: 10.1109/JBHI.2024.3487012

Fuze Tian, Haojie Zhang, Yang Tan, Lixian Zhu, Lin Shen, Kun Qian, Bin Hu, Bjorn W Schuller, Yoshiharu Yamamoto

{"title":"An On-Board Executable Multi-Feature Transfer-Enhanced Fusion Model for Three-Lead EEG Sensor-Assisted Depression Diagnosis.","authors":"Fuze Tian, Haojie Zhang, Yang Tan, Lixian Zhu, Lin Shen, Kun Qian, Bin Hu, Bjorn W Schuller, Yoshiharu Yamamoto","doi":"10.1109/JBHI.2024.3487012","DOIUrl":"https://doi.org/10.1109/JBHI.2024.3487012","url":null,"abstract":"The development of affective computing and medical electronic technologies has led to the emergence of Artificial Intelligence (AI)-based methods for the early detection of depression. However, previous studies have often overlooked the necessity for the AI-assisted diagnosis system to be wearable and accessible in practical scenarios for depression recognition. In this work, we present an on-board executable multi-feature transfer-enhanced fusion model for our custom-designed wearable three-lead Electroencephalogram (EEG) sensor, based on EEG data collected from 73 depressed patients and 108 healthy controls. Experimental results show that the proposed model exhibits low-computational complexity (65.0 K parameters), promising Floating-Point Operations (FLOPs) performance (26.6 M), real-time processing (1.5 s/execution), and low power consumption (320.8 mW). Furthermore, it requires only 202.0 MB of Random Access Memory (RAM) and 279.6 KB of Read-Only Memory (ROM) when deployed on the EEG sensor. Despite its low computational and spatial complexity, the model achieves a notable classification accuracy of 95.2%, specificity of 96.9%, and sensitivity of 94.0% under independent test conditions. These results underscore the potential of deploying the model on the wearable three-lead EEG sensor for assisting in the diagnosis of depression.","PeriodicalId":13073,"journal":{"name":"IEEE Journal of Biomedical and Health Informatics","volume":"PP ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142521774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Attention Transfer in Heterogeneous Networks Fusion for Drug Repositioning. 异构网络融合中的注意力转移，促进药物重新定位。

IF 6.7 2区医学

IEEE Journal of Biomedical and Health Informatics Pub Date : 2024-10-28 DOI: 10.1109/JBHI.2024.3486730

Xinguo Lu, Fengxu Sun, Jinxin Li, Jingjing Ruan

{"title":"Attention Transfer in Heterogeneous Networks Fusion for Drug Repositioning.","authors":"Xinguo Lu, Fengxu Sun, Jinxin Li, Jingjing Ruan","doi":"10.1109/JBHI.2024.3486730","DOIUrl":"https://doi.org/10.1109/JBHI.2024.3486730","url":null,"abstract":"Computational drug repositioning which accelerates the process of drug development is able to reduce the cost in terms of time and money dramatically which brings promising and broad perspectives for the treatment of complex diseases. Heterogeneous networks fusion has been proposed to improve the performance of drug repositioning. Due to the difference and the specificity including the network structure and the biological function among different biological networks, it poses serious challenge on how to represent drug features and construct drug-disease associations in drug repositioning. Therefore, we proposed a novel drug repositioning method (ATDR) that employed attention transfer across different networks constructed by the deeply represented features integrated from biological networks to implement the disease-drug association prediction. Specifically, we first implemented the drug feature characterization with the graph representation of random surfing for different biological networks, respectively. Then, the drug network of deep feature representation was constructed with the aggregated drug informative features acquired by the multi-modal deep autoencoder on heterogeneous networks. Subsequently, we accomplished the drug-disease association prediction by transferring attention from the drug network to the drug-disease interaction network. We performed comprehensive experiments on different datasets and the results illustrated the outperformance of ATDR compared with other baseline methods and the predicted potential drug-disease interactions could aid in the drug development for disease treatments.","PeriodicalId":13073,"journal":{"name":"IEEE Journal of Biomedical and Health Informatics","volume":"PP ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142521775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0