Proceedings of the 5th International Conference on Bioinformatics and Computational Biology最新文献

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Circadian rhythm of brain activity estimated using visual synchronization tasks: relations between brain activity and living activity 使用视觉同步任务估计大脑活动的昼夜节律:大脑活动和生活活动之间的关系
K. Aoki
{"title":"Circadian rhythm of brain activity estimated using visual synchronization tasks: relations between brain activity and living activity","authors":"K. Aoki","doi":"10.1145/3035012.3035028","DOIUrl":"https://doi.org/10.1145/3035012.3035028","url":null,"abstract":"The authors proposed the method to estimate the performance of motion control function with a visual synchronization task. The proposed method is enable to measure and estimate the motor control function precisely and easily. This paper confirms the ability of the proposed method to observe the circadian rhythm of a brain activity of a human. This paper shows the proposed method and the measuring process. Then, the experiments are shows and are discussed. The experiments include 165 trials. There are objective differences of the performances of a brain function among time zones. T-test confirms this result.","PeriodicalId":130142,"journal":{"name":"Proceedings of the 5th International Conference on Bioinformatics and Computational Biology","volume":"184 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120980606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Comparison of standardization approaches applied to metabolomics data 代谢组学数据标准化方法的比较
Qingxia Yang, Bo Li, Feng Zhu
{"title":"Comparison of standardization approaches applied to metabolomics data","authors":"Qingxia Yang, Bo Li, Feng Zhu","doi":"10.1145/3035012.3035023","DOIUrl":"https://doi.org/10.1145/3035012.3035023","url":null,"abstract":"Some factors such as unwanted variations might affect the identification of biomarkers in metabolomics and proteomics analysis, which needs preprocessing including normalization (also named as standardization) by the standardization approach prior to marker selection. Many standardization approaches were applied to analysis of the metabolomics, and even proteomics data. But there are rarely comprehensive comparison of the standardization performance based on the sample size and various methods. The current study performed an overall comparison aiming at these methods based on a metabolomics dataset. As a result, 15 standardization approaches were classified into four groups according to the standardization performances of different sample sizes. The Log Transformation and the VSN method were regarded as the Superior performance methods, but the Contrast method was performed consistently worst in all datasets of various sample size. This study could provide a useful guidance for the choice of befitting standardization approaches when carrying out the metabolomics and proteomics analysis based on LC/MS.","PeriodicalId":130142,"journal":{"name":"Proceedings of the 5th International Conference on Bioinformatics and Computational Biology","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126748660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A new focusing excitation method based on magnetic induction tomography 基于磁感应层析成像的聚焦激励新方法
Yi Lv, Haijun Luo
{"title":"A new focusing excitation method based on magnetic induction tomography","authors":"Yi Lv, Haijun Luo","doi":"10.1145/3035012.3035025","DOIUrl":"https://doi.org/10.1145/3035012.3035025","url":null,"abstract":"Magnetic induction tomography (MIT) is a new and non-invasive reconstruction method which reconstructs the conductivity distribution information within the target object by the eddy current signal. Due to the low conductivity for human, the eddy current field reflecting human conductivity is so weak. On the basis of analyzing magnetic field and excitation magnetic field, the conical spiral coil is proposed which can produce the focusing magnetic field. The measurement model with the target object whose parameters are near to the tissue is established for the focusing excitation coil. The primary field and the eddy current field produced within the target object are calculated and analyzed comparatively. The results show that the proposed focusing excitation coils that produces the excitation field and the eddy current field have the focusing effect, that is to say it can produce the focusing eddy current field, which provides an effect method for MIT from the eddy current source.","PeriodicalId":130142,"journal":{"name":"Proceedings of the 5th International Conference on Bioinformatics and Computational Biology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129947849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Classification of multi-class microarray datasets using a minimizing class-overlapping based ECOC algorithm 基于最小化类重叠的ECOC算法的多类微阵列数据集分类
Haiyue Yu, Kunhong Liu
{"title":"Classification of multi-class microarray datasets using a minimizing class-overlapping based ECOC algorithm","authors":"Haiyue Yu, Kunhong Liu","doi":"10.1145/3035012.3035018","DOIUrl":"https://doi.org/10.1145/3035012.3035018","url":null,"abstract":"The classification of multi-class microarray datasets is much more difficult compared with the binary datasets because the former usually consist of unbalanced data with a smaller sample size in each class. Our paper focuses on the multi-class problem, and proposes a new method based on a class-overlapping measure, named as Minimum Class-Overlapping Error-Correcting Output Codes (MCO-ECOC). In this algorithm, important variables are selected through different filter methods firstly. Then, the class overlapping is measured in training sets, the algorithm searches all class splitting schemes, and select the one minimizing the class-overlapping measure. Each column of the coding matrix represents such a splitting scheme. And then all the coding matrixs are combined by eliminating the redundant columns to make the final ensemble system compact. Neural networks are used as binary classifiers. MCO-ECOC algorithm is applied to classify the different multi-class microarray datasets, and the output of each base learner are fused to produce the final decision based on the Hamming distance. The experimental results show that the performance of MCO-ECOC is significantly higher than those obtained by DECOC and Forest ECOC.","PeriodicalId":130142,"journal":{"name":"Proceedings of the 5th International Conference on Bioinformatics and Computational Biology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129459163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
A fast microbial detection algorithm based on high-throughput sequencing data 基于高通量测序数据的微生物快速检测算法
Jiangyu Li, Xiaolei Wang, Dongsheng Zhao, Yiqing Mao, Qian Cheng
{"title":"A fast microbial detection algorithm based on high-throughput sequencing data","authors":"Jiangyu Li, Xiaolei Wang, Dongsheng Zhao, Yiqing Mao, Qian Cheng","doi":"10.1145/3035012.3035014","DOIUrl":"https://doi.org/10.1145/3035012.3035014","url":null,"abstract":"Objective Design a rapid microbial detection algorithm that analyzes the sequencing data while sequencing, which can improve the speed of pathogenic microbial detection. Method A 'analysis while sequencing' method is used to analyze the sequencing data, the method uses the detection algorithm to analyze the sequencing data generated by the sequencer periodically. The reference microbial genomes are grouped. For each group the algorithm extracts sequencing reads mapped to the microbial genomes and then filters the human genome data, then the algorithm assembles the reads left and aligns the assembled contigs to the microbial genomes. Result For the simulated data, the new algorithm achieves speedup of 10 compared with RINS when the microorganisms in the sample have ref-genomes, both results are consistent and the new algorithm gets longer contigs. The new algorithm achieves an average speedup of 9 with no ref-genomes, and it obtains more complete sequence. For the real data, the new algorithm achieves an average speedup of 3 compared with RINS, and both detection results are the same. When verifying the Sequencing-by-side method, a reliable result can be obtained with a certain scale of sequencing data. Conclusion The 'analysis while sequencing' methods can improve pathogen detection speed, and have good application prospects.","PeriodicalId":130142,"journal":{"name":"Proceedings of the 5th International Conference on Bioinformatics and Computational Biology","volume":"244 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123100426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extrapolation-accelerated aggregation multigrid with block relaxations for GeneRank problems GeneRank问题的块松弛外推加速聚合多网格
Zhao-Li Shen, Tingzhu Huang, Chun Wen, Hong-Fan Zhang, B. Carpentieri
{"title":"Extrapolation-accelerated aggregation multigrid with block relaxations for GeneRank problems","authors":"Zhao-Li Shen, Tingzhu Huang, Chun Wen, Hong-Fan Zhang, B. Carpentieri","doi":"10.1145/3035012.3035024","DOIUrl":"https://doi.org/10.1145/3035012.3035024","url":null,"abstract":"This paper proposes an aggregation multigrid method for computing the GeneRank problem. In this multigrid, the GeneRank transition matrix's formulation is well exploited, and a Block-Jacobi relaxation based on the aggregates, is employed. This block relaxation is well-defined in the multigrid hierarchy and expected to be more efficient than the point-wise version. Besides, the whole method is further accelerated by an extrapolation technique. Numerical experiments demonstrate the potential of this method for computing GeneRank problems.","PeriodicalId":130142,"journal":{"name":"Proceedings of the 5th International Conference on Bioinformatics and Computational Biology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116448455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An image encryption algorithm based on compressed sensing and dual-tree complex wavelet transform 基于压缩感知和双树复小波变换的图像加密算法
Jiwen Dong, Ziru Zhao, Hengjian Li
{"title":"An image encryption algorithm based on compressed sensing and dual-tree complex wavelet transform","authors":"Jiwen Dong, Ziru Zhao, Hengjian Li","doi":"10.1145/3035012.3035013","DOIUrl":"https://doi.org/10.1145/3035012.3035013","url":null,"abstract":"Combined image encryption with the process of compressed sensing (CS) which based on dual-tree complex wavelet transform, we came up with the image encryption algorithm which based on the theory of CS and double random phase encoding (DRPE). Firstly, adopting DT-CWT represent the image sparsely. It can enhance the image edge and texture, it also can attain directional feature information. Secondly, utilizing chaotic system to product chaos sequence as the measurement matrix on the process of CS. At the same time, the values of initial chaotic parameters are the keys. Finally, we selected DRPE on measurements to finish the process of secondary encryption. The values of seeds which are used to generate two random phase masks are the keys of secondary encryption. In the process of decryption, providing the correct values of keys can generate the chaotic measurement matrix and random phase masks to be used for decryption. Orthogonal matching pursuit (OMP) algorithm is employed to reconstruct the original image approximately. Compared with several existing algorithms, this encryption scheme can reconstruct a higher quality image. It has higher robustness and higher sensitivity to the initial keys.","PeriodicalId":130142,"journal":{"name":"Proceedings of the 5th International Conference on Bioinformatics and Computational Biology","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128699986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Three-dimensional geometric statistical model based on locating feature points of maximal curvature flow 基于最大曲率流特征点定位的三维几何统计模型
Hui Yu, Wu Jun-Sheng, Y. Bin, Zhang Chen
{"title":"Three-dimensional geometric statistical model based on locating feature points of maximal curvature flow","authors":"Hui Yu, Wu Jun-Sheng, Y. Bin, Zhang Chen","doi":"10.1145/3035012.3035016","DOIUrl":"https://doi.org/10.1145/3035012.3035016","url":null,"abstract":"Aiming at the present problem that the spine and the part of the spine lack the sample library of geometric statistical model of different age groups, this paper studies a method to construct the three-dimensional geometric statistic model based on the locating feature points of maximum curvature flow. In this method, the 3D reconstructed human lumbar vertebrae model is adaptively identified and located based on the feature points of the normal curvature maxima, so as to the sample matrix is generated for each model. Then the improved ICP algorithm is used to align and register the sample matrix. Finally, the PCA (Principal Component Analysis) is used to train the model template after registration, in order to get the sample library of geometry statistical model of spine.","PeriodicalId":130142,"journal":{"name":"Proceedings of the 5th International Conference on Bioinformatics and Computational Biology","volume":"116 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134056555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A developed apriori algorithm based on frequent matrix 一种基于频繁矩阵的先验算法
Kun Niu, Haizhen Jiao, Zhipeng Gao, Cheng Chen, Huiyang Zhang
{"title":"A developed apriori algorithm based on frequent matrix","authors":"Kun Niu, Haizhen Jiao, Zhipeng Gao, Cheng Chen, Huiyang Zhang","doi":"10.1145/3035012.3035019","DOIUrl":"https://doi.org/10.1145/3035012.3035019","url":null,"abstract":"Apriori is the most famous frequent pattern mining method. It scans dataset repeatedly and generate item sets by bottom-top approach. In order to reduce time complexity, we proposed a modified algorithm named as Frequent Matrix Apriori (FMA). Firstly, FMA scans the dataset only once to store frequent item information in a frequent matrix. Then, FMA discretize the matrix by the minimum support parameter which is generated automatically. Thirdly, it scans the discretized frequent matrix and find the most frequent item sets recursively. Experimental results proved that FMA is more effective than Apriori on time consuming with similar accuracy.","PeriodicalId":130142,"journal":{"name":"Proceedings of the 5th International Conference on Bioinformatics and Computational Biology","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126038192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Breast mass lesion classification in mammograms by transfer learning 基于迁移学习的乳房x光片肿块病变分类
Fan Jiang, Hui Liu, Shaode Yu, Yaoqin Xie
{"title":"Breast mass lesion classification in mammograms by transfer learning","authors":"Fan Jiang, Hui Liu, Shaode Yu, Yaoqin Xie","doi":"10.1145/3035012.3035022","DOIUrl":"https://doi.org/10.1145/3035012.3035022","url":null,"abstract":"Automatic classification of breast mass lesions in mammographic images remains an unsolved problem. This paper explored the technique of transfer learning to tackle this problem. It utilized the convolutional neural network (CNN) of GoogLeNet and AlexNet pre-trained on a large-scale visual database. The performance was evaluated a new dataset in terms of the area under the receiver operating characteristic curves (AUC). Results demonstrate that GoogLeNet (AUC=0.88) outperforms AlexNet (AUC=0.83) and other state-of-the-art traditional approaches in breast cancer diagnosis. The technique of transfer learning not only overcomes the unsatisfactory performance of traditional approaches, but also breaks the obstacle of limited samples for building deep CNNs.","PeriodicalId":130142,"journal":{"name":"Proceedings of the 5th International Conference on Bioinformatics and Computational Biology","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122318868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 68
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