Head & Face Medicine最新文献

{"title":"The COVID-19 pandemic and its possible impact on the treatment of odontogenic and intraoral abscesses.","authors":"Florian D Grill, Paulina Rothlauf, Lucas M Ritschl, Herbert Deppe, Herbert Stimmer, Florian Scheufele, Matthias Schwarz, Klaus-Dietrich Wolff, Andreas M Fichter","doi":"10.1186/s13005-023-00381-2","DOIUrl":"10.1186/s13005-023-00381-2","url":null,"abstract":"<p><p>Most odontogenic and intraoral abscesses can be treated on an outpatient basis with local anesthesia. However, severe disease progression may require an incision under general anesthesia (GA) with postoperative inpatient treatment. This study aimed to evaluate the first \"COVID-19 year\" in Germany and compare the first \"COVID-19 year\" with the two previous years. All consecutive cases with odontogenic or intraoral abscesses treated in an outpatient or inpatient setting between 2018 and 2021 were included in this study. Data were collected, including the type of anesthesia, length of hospital stay, and healthcare costs. Despite the lower total number of abscess treatments in the first year of COVID-19 (n = 298 patients) than that in the two previous years (n = 663 patients), the number of advanced abscesses requiring intervention under GA was significantly higher (p < 0.001). This increased burden of care was also reflected in increased healthcare costs. The measures taken against the COVID-19 pandemic had an impact on the course of other diseases, for example, odontogenic and intraoral abscesses. The results showed an emerging conflict in patient care during the pandemic crisis that should be considered in possible future pandemics.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10413344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Syndromic Craniosynostosis in a Child With Fontaine Progeroid Syndrome: A Rare Genetic Disorder and the Surgical Management","authors":"Thao T. Wolbert, Nathaniel A. Teitler, Lauren Weis, Anna Podber, Jason J. Miller","doi":"10.1177/27325016231193701","DOIUrl":"https://doi.org/10.1177/27325016231193701","url":null,"abstract":"We present a case of cranial vault remodeling in a patient with Fontaine Progeroid Syndrome. At birth, the patient presented with midfacial retrusion, pansynostosis, and significant agenesis of the central vertex skull. Genetic testing revealed a de novo variant in the SLC25A24 gene, confirming the diagnosis of Fontaine Progeroid Syndrome. For craniosynostotis management of her pansynostosis and the large central vertex agenesis, surgical reconstruction was purposely delayed to allow ossification of the cranial vault. Subsequently, the cranial vault expansion was performed at the age of 4. Intraoperatively, significant dense adherence of bilateral temporal, parietal, and frontal bones to the underlying dural lakes was noted. This is the first case report known in the literature regarding suggested surgical management of the syndromic craniosynostosis with an enormous central skull agenesis.","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78860080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Primary cold atmospheric plasma combined with low dose cisplatin as a possible adjuvant combination therapy for HNSCC cells-an in‑vitro study.","authors":"Teresa F Brunner, Florian A Probst, Matthias Troeltzsch, Sabina Schwenk-Zieger, Julia L Zimmermann, Gregor Morfill, Sven Becker, Ulrich Harréus, Christian Welz","doi":"10.1186/s13005-023-00386-x","DOIUrl":"10.1186/s13005-023-00386-x","url":null,"abstract":"","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10050553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of Regional Morphological Changes in Metopic Craniosynostosis Following Endoscopic Strip Craniectomy With Postoperative Helmeting: Predictors for Success","authors":"Alfredo Cepeda, H. T. Nguyen, Chioma G. Obinero, G. Washington, T. Littlefield, M. Greives, P. D. Nguyen","doi":"10.1177/27325016231191638","DOIUrl":"https://doi.org/10.1177/27325016231191638","url":null,"abstract":"Metopic craniosynostosis (MC) represents 10% to 25% of craniosynostosis cases. Endoscopic-assisted strip craniectomy (ESC) with orthotic molding therapy provides a minimally invasive alternative to open fronto-orbital advancement. Herein, we describe a 3D photogrammetry methodology for measurement of regional cranial growth and inter-frontal angle (IFA) as well as examine factors that may contribute to successful outcomes after ESC. A retrospective review was performed on patients with MC treated with ESC and band therapy from 2015 to 2019. Patients obtained 3D photogrammetry preoperatively, postoperatively, and post-helmet therapy. A survey was administered to 14 independent raters, who were asked to determine treatment success based on subjective visual assessment of preoperative and post-banding images. Patients were considered to have successful therapy when ≥75% of raters were in agreeance. Thirteen patients met inclusion criteria. Average age at surgery was 3.5 months, with 53.9% of these patients deemed as a successful outcome on aggregate reviewer scores. For patients with successful treatment, there was a trend toward younger at surgery (2.9 months vs 4.2 months, P = .09) and at initiation of helmeting (3.3 months vs 4.8 months, P = .07). Regional root mean square identified significant differences between frontal and temporal (14.04 mm vs 7.39 mm, P = .02) and temporal and parietal (7.39 mm vs 15.37 mm, P = .002) regions. Average postoperative IFA was significantly improved compared to preoperative values (128.19° vs 117.9°, P = .02). Logistic regression modeling found no significant predictors of success. Though not statistically significant, patients with MC with successful outcomes following ESC and banding were younger at surgery and time of helmeting. Our analysis of regional cranial growth and IFA demonstrated significant differences, which coincide with expected morphologic changes in this patient population. Our results demonstrate the potential for this technology in surgical evaluation and support the importance of early diagnosis and treatment by craniofacial surgeons.","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76761136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scopus and Scotus: Challenges to Diversity Will Require New Ideas","authors":"J. V. van Aalst","doi":"10.1177/27325016231190749","DOIUrl":"https://doi.org/10.1177/27325016231190749","url":null,"abstract":"","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78909170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cleft Lip and Palate Care: A Healthcare Cost and Utilization Project Analysis","authors":"Kimberly H. Khoo, C. D. Lopez, Krissia M. Rivera Perla, Cynthia T. Yusuf, Joseph Lopez, R. Redett, Robin Yang","doi":"10.1177/27325016231191235","DOIUrl":"https://doi.org/10.1177/27325016231191235","url":null,"abstract":"Increasing emphasis on reduction of healthcare costs has caused rates of outpatient cleft lip and palate-related procedures to rise. This study aims to describe patient and hospital characteristics associated with cleft repair and related surgeries and to assess differences in these characteristics against those undergoing inpatient cleft procedures. Data was collected from the 2016 to 2018 National Inpatient Sample (NIS) and the 2016 to 2018 Nationwide Ambulatory Surgery Sample (NASS) from the Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality (AHRQ). The databases were queried for International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) codes and Current Procedural Terminology (CPT) codes, respectively, describing cleft lip and palate-related procedures. Variables described were categorized into 2 main groups of patient demographics and hospital characteristics. A total of 271 patients were included from the NIS and 3122 patients from the NASS. In both settings, the most common insurance used for cleft lip surgeries was Medicaid (46.7% vs 50.7%); the same was true for cleft palate (50.7% vs 53.5%). The distribution of zip code-based income quartiles was similar between settings for both cleft procedures. The most common location and teaching status of the hospitals was urban, teaching hospitals. This study demonstrates that patient and hospital characteristics are similar between inpatient and outpatient cleft surgeries. Patients were primarily in the 2 lower income quartiles and enrolled in Medicaid. More granular studies defining the social determinants of health in the cleft lip and palate populations may improve care for these patients.","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90819475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Head Circumference is Relatively Larger Than Size: A Novel Screening Tool for Infants With Sagittal Craniosynostosis","authors":"Demetrius M. Coombs, N. Sinclair, N. McNinch, N. Patel","doi":"10.1177/27325016231193131","DOIUrl":"https://doi.org/10.1177/27325016231193131","url":null,"abstract":"The efficacy of minimally invasive techniques for addressing isolated sagittal craniosynostosis decreases with age; thus, timely referral is critical. We sought to identify a screening tool using data from well-child visits. We hypothesized that many infants with sagittal craniosynostosis, but no macrocephaly based on growth chart plotting, in fact have a relative macrocephaly. All infants with CT and surgically/pathologically confirmed isolated sagittal craniosynostosis were identified. Growth chart data was collected (head circumference (HC), weight, crown-to-toe-length, and World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) percentiles and deviation ( z-scores)). Relative macrocephaly was defined as head circumference >2SD from size (weight and/or length). Initial pilot screen indicated that WHO growth chart data has utility as a screening tool. Subsequent retrospective case-control study with area under the curve (AUC) analysis revealed that HC:length ratio ≥0.71 is indicative of isolated sagittal craniosynostosis as young as 1 week of age, while HC:length ratio ≥0.67 represents the maximization of sensitivity (0.89) and specificity (1.00) as early as 2 weeks old. Prospective internal validation with logistic regression demonstrated that at ages 1 to 2 months greater discriminatory value HC:length ratio was observed. When length is added to head circumference as a screening tool we may identify an abnormal growth pattern beginning as early as 1 week. This represents an opportunity to design an automated alert easily programed into the electronic medical records and may prompt pediatricians to refer patients to craniofacial surgeons early.","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76464410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteogenic stimulation of osteoprogenitors by putamen ovi peptides and hyaluronic acid.","authors":"Jörg Neunzehn, Franziska Alt, Hans-Peter Wiesmann, Benjamin Kruppke","doi":"10.1186/s13005-023-00380-3","DOIUrl":"10.1186/s13005-023-00380-3","url":null,"abstract":"<p><p>Eggshell peptides (EP) majorly contribute to rapid bone building in chicks, wherefore this paper investigated their potential for stimulating osteogenesis in vitro. In this study, the effects of EP, also called putamen ovi peptides and a combination of hyaluronic acid with EP in cell culture medium were tested towards proliferation, differentiation, gene expression and mineralization of bovine osteoprogenitors and primary human osteoblasts. The influence of EP at concentrations of 0.005 g/L, 0.5 g/L and 0.5 g/L with 0.25% hyaluronic acid was analyzed using immunocytochemical staining of bone-specific matrix proteins, namely collagen type I, osteonectin, osteopontin and osteocalcin, to prove osteoblastic differentiation. Additionally, Richardson-staining was performed. All tests revealed a superior osteoblastic differentiation with EP at 0.5 g/L after 5 days of cultivation. Hyaluronic acid alone showed controversial results and partially constrained osteoblastic differentiation in combination with EP to a level as low as for pure EP at 0.005 g/L. Of particular interest is the osteoblast-typical mineralization, as an important indicator of bone formation, which was measured indirectly via the calcium concentration after cultivation over 4 weeks. The mineralization showed an increase by a factor of 286 during the cultivation of primary human osteoblasts with hyaluronic acid and EP. Meanwhile, cell cultures treated with EP (0.5 g/L) only showed an 80-fold increase in calcium concentration.The influence of EP (0.5 g/L) on primary human osteoblasts was investigated by gene expression after 2 weeks of cultivation. Microarray and qRT-PCR analysis showed a strongly increased expression of main important genes in bone formation, bone regeneration and the physiological bone remodelling processes. Namely, BMP 2, osteopontin and the matrix metalloproteinases 1 and 9, were present during in vitro osteoprogenitor culture with EP. By explicitly underlining the potential of eggshell peptides for stimulating osteogenesis, as well as emphasizing complex and controversial interaction with hyaluronan, this manuscript is relevant for developing new functionalized biomaterials for bone regeneration.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10344166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Algorithmic Elementary-Age Nasal Reconstruction for Binder Syndrome","authors":"J. Blum, D. Villavisanis, D. Cho, Liana Cheung, N. Plana, S. Bartlett, Jesse A. Taylor, J. Swanson","doi":"10.1177/27325016231191260","DOIUrl":"https://doi.org/10.1177/27325016231191260","url":null,"abstract":"Background: Nasomaxillary hypoplasia, or Binder syndrome, is conventionally treated at skeletal maturity (SKM). However, our institution has employed a stratified treatment algorithm, treating severe patients with serial nasal expansion beginning at elementary school age (5-11 years) to expand the soft tissues and improve appearance prior to definitive rhinoplasty at SKM. This study evaluates the treatment patterns and outcomes of Binder syndrome employing this pathway. Methods: Eight cases of nasomaxillary hypoplasia were identified from a database of rhinoplasties performed between 2006 and 2020 at a tertiary children’s hospital. Photomorphometric analyses were conducted on basal, frontal, and lateral photographs. Goode’s ratio was used to assess change in projection, and pronasale to ala distance was measured bilaterally as a proxy of symmetry. Changes in symmetry were calculated using bilateral nasal width ratio. Results: In our sample, 6 patients (75.0%) had initial rhinoplasty prior to SKM, with 3 undergoing serial silastic implant placement, one with complicated implant placement followed by autologous reconstruction, and 2 undergoing serial expansion with allograft rib cartilage grafts. Average age at initial rhinoplasty was 6.3 (range 5.2-8.8) years for the pre-SKM group and 15.6 (range 14.1-17.1) years for the post-SKM group. Patients in the pre-SKM rhinoplasty group underwent more procedures than those at SKM (2.3 vs 1.5, respectively). The average change in nasal parameters was −0.029 for Goode’s ratio and −9.5° for nasolabial angle. The average post-operative nasal symmetry index was 0.98 representing near perfect symmetry. There was no significant difference in the degree of improvement in nasolabial angle, Goode’s ratio, or nasal symmetry between SKM and pre-SKM cohorts (all P > .05). Conclusion: Among patients with Binder syndrome, those treated initially at elementary-age were able to achieve similar improvements in nasal indices to those treated at SKM. This approach allows patients to live their key developmental years with less stigmata of their facial difference but requires more surgical intervention.","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73893911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Puricelli biconvex arthroplasty: an experimental study in sheep.","authors":"Renan Langie,&nbsp;Viviane Neves Pacheco,&nbsp;Vinicius Matheus Szydloski,&nbsp;Adriana Corsetti,&nbsp;Alexandre Silva de Quevedo,&nbsp;Fábio Pinto da Silva,&nbsp;Fabrício Mezzomo Collares,&nbsp;Fernanda Visioli,&nbsp;Deise Ponzoni,&nbsp;Edela Puricelli","doi":"10.1186/s13005-023-00379-w","DOIUrl":"https://doi.org/10.1186/s13005-023-00379-w","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to establish a sheep model of the Puricelli biconvex arthroplasty (ABiP) technique in sheep for evaluating its functional, biological and histological parameters.</p><p><strong>Methods: </strong>Ten Corriedale black sheep were submitted to TMJ total reconstruction with poly(methyl methacrylate) (PMMA) using ABiP and euthanized after 45 (n = 5) or 90 (n = 5) days. Control animals (n = 2) underwent sham operations and were euthanized after 45 days. Variables were assessed before the surgery (T0), immediately after (T1) and at 45 or 90 postoperative days (T2).</p><p><strong>Results: </strong>Histological analyses showed regression of inflammatory cells over the follow-up period. PMMA showed reduced porosity and roughness in the articular contact area. PMMA temporal components showed linear and volumetric wear in comparison to control, but no foreign body reaction was observed. The reconstructions were stable in all animals. The amplitude of mouth opening and left lateral movements were maintained, except for a reduction in the range of right lateral movements at day 90 in the experimental group. Clinical, macroscopic and radiographic observations showed that the reconstructions were stable.</p><p><strong>Conclusions: </strong>The analysis of functional, biological and histological parameters in sheep submitted to ABiP showed stable results of the procedure, with maintenance of body weight and all mandibular movements, save contralateral mandibular movement, suggesting that joint function was completely maintained following the procedure. This experimental study provides support for clinical results previously reported of the ABiP technique in TMJ reconstruction procedures.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2023-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10394908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9929266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}