Gabriela Silveira de Araujo, Leandro Dorigan de Macedo, Alfredo Ribeiro-Silva, Hilton Marcos Alves Ricz, Lara Maria Alencar Ramos Innocentini
{"title":"Transformation of low-grade follicular lymphoma to a high-grade follicular lymphoma with the histopathological diagnosis from oral biopsy: a case report.","authors":"Gabriela Silveira de Araujo, Leandro Dorigan de Macedo, Alfredo Ribeiro-Silva, Hilton Marcos Alves Ricz, Lara Maria Alencar Ramos Innocentini","doi":"10.1016/j.htct.2023.01.010","DOIUrl":"10.1016/j.htct.2023.01.010","url":null,"abstract":"","PeriodicalId":12958,"journal":{"name":"Hematology, Transfusion and Cell Therapy","volume":" ","pages":"S380-S384"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9161429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Oliveira E Costa, Ana Barreira, Manuel Cunha, Fernando Salvador
{"title":"Polycythemia and JAK2 variant N1108S: cause-and-effect or coincidence?","authors":"Ana Oliveira E Costa, Ana Barreira, Manuel Cunha, Fernando Salvador","doi":"10.1016/j.htct.2023.01.006","DOIUrl":"10.1016/j.htct.2023.01.006","url":null,"abstract":"","PeriodicalId":12958,"journal":{"name":"Hematology, Transfusion and Cell Therapy","volume":" ","pages":"S376-S379"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726029/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10834264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Besim Fazıl Ağargün, Murat Özbalak, Übeyde Ayşe Gülseren, Gülçin Yegen, Sevgi Kalayoğlu Beşışık
{"title":"Central nervous system involvement of mantle cell lymphoma: Case report and review of the literature.","authors":"Besim Fazıl Ağargün, Murat Özbalak, Übeyde Ayşe Gülseren, Gülçin Yegen, Sevgi Kalayoğlu Beşışık","doi":"10.1016/j.htct.2022.10.002","DOIUrl":"10.1016/j.htct.2022.10.002","url":null,"abstract":"","PeriodicalId":12958,"journal":{"name":"Hematology, Transfusion and Cell Therapy","volume":" ","pages":"S367-S372"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10738489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thulasi Raman Ramalingam, J Subramanian, I Nagarathinam, C Chandran, L Vaidhyanathan, J M Easow
{"title":"An interesting case of chronic myeloid leukemia with twists and turns.","authors":"Thulasi Raman Ramalingam, J Subramanian, I Nagarathinam, C Chandran, L Vaidhyanathan, J M Easow","doi":"10.1016/j.htct.2023.02.001","DOIUrl":"10.1016/j.htct.2023.02.001","url":null,"abstract":"<p><p>Additional cytogenetic abnormalities (ACA) are known to crop up in Ph<sup>+</sup> cells of chronic myeloid leukemia (CML) patients due to cytogenetic evolution. But the frequency of molecular evolution and ACA is much less in Ph<sup>-</sup> cells of CML patients and is poorly understood. We report an interesting and rare case of Ph<sup>+</sup> CML, who progressed to B lymphoblastic crisis, achieved remission, and later developed Ph<sup>-</sup> acute myeloid leukemia (AML) with KMT2A gene rearrangement and no detectable BCR- ABL transcripts.</p>","PeriodicalId":12958,"journal":{"name":"Hematology, Transfusion and Cell Therapy","volume":" ","pages":"S385-S388"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726053/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9520128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Valderez Ravaglio Jamur, Mateus de Oliveira Lisboa, Ana Paula Azambuja, Paulo Roberto Slud Brofman
{"title":"Case report: CD8 positive T-cell Prolymphocytic Leukemia presenting complex karyotype with a rare chromosomal abnormality der(2)t(1;2)(q21;q37) and additional signals of the genes MYC, IGH, and TP53.","authors":"Valderez Ravaglio Jamur, Mateus de Oliveira Lisboa, Ana Paula Azambuja, Paulo Roberto Slud Brofman","doi":"10.1016/j.htct.2023.07.009","DOIUrl":"10.1016/j.htct.2023.07.009","url":null,"abstract":"","PeriodicalId":12958,"journal":{"name":"Hematology, Transfusion and Cell Therapy","volume":" ","pages":"S393-S397"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10597749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jie Yang , Yiming Yang , Li Gao , Xueyu Jiang , Juan Sun , Zhicheng Wang , Rufeng Xie
{"title":"Adverse effects of microparticles on transfusion of stored red blood cell concentrates","authors":"Jie Yang , Yiming Yang , Li Gao , Xueyu Jiang , Juan Sun , Zhicheng Wang , Rufeng Xie","doi":"10.1016/j.htct.2024.01.007","DOIUrl":"10.1016/j.htct.2024.01.007","url":null,"abstract":"<div><h3>Background</h3><div>Systemic and pulmonary coagulopathy and inflammation are important characteristics of transfusion-related acute lung injury (TRALI). Whether microparticles that accumulate in transfused red blood cell concentrates (RBCs) have proinflammatory and procoagulant potential and contribute to adverse reactions of RBC transfusions is unclear.</div></div><div><h3>Aim</h3><div>To investigate the ability of microparticles in stored RBCs to promote thrombin generation and induce human pulmonary microvascular endothelial cell (HMVEC) activation and damage.</div></div><div><h3>Methods</h3><div>The number and size of microparticles were determined by flow cytometric and nanoparticle tracking analyses, respectively. Thrombin generation and the intrinsic coagulation pathway were assayed by a calibrated automated thrombogram and by measuring activated partial thromboplastin time (aPTT), respectively. The expression of ICAM-1 and the release of cytokines by endothelial cells were detected by flow cytometric analyses. HMVEC damage was assessed by incubating lipopolysaccharide-activated endothelial cells with MP-primed polymorphonuclear neutrophils (PMNs).</div></div><div><h3>Results</h3><div>The size of the microparticles in the RBC supernatant was approximately 100–300 nm. Microparticles promoted thrombin generation in a dose-dependent manner and the aPTT was shortened. Depleting microparticles from the supernatant of RBCs stored for 35 days by either filtration or centrifugation significantly decreased the promotion of thrombin generation. The expression of ICAM-1 on HMVECs was increased significantly by incubation with isolated microparticles. Furthermore, microparticles induced the release of interleukin-6 (IL-6) and interleukin-8 (IL-8) from HMVECs. Microparticles induced lipopolysaccharide-activated HMVEC damage by priming PMNs, but this effect was prevented by inhibiting the PMNs respiratory burst with apocynin.</div></div><div><h3>Conclusion</h3><div>Microparticles in stored RBCs promote thrombin generation, HMVEC activation and damage which may be involved in TRALI development.</div></div>","PeriodicalId":12958,"journal":{"name":"Hematology, Transfusion and Cell Therapy","volume":"46 ","pages":"Pages S48-S56"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140190501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chao Zhou , Xiaozhen Hong , Xinyu Huang , Jihua Ma , Xuejun Chen
{"title":"Blood chimerism associated with IVF in monochorionic twins with concordant sex: case report","authors":"Chao Zhou , Xiaozhen Hong , Xinyu Huang , Jihua Ma , Xuejun Chen","doi":"10.1016/j.htct.2024.02.022","DOIUrl":"10.1016/j.htct.2024.02.022","url":null,"abstract":"","PeriodicalId":12958,"journal":{"name":"Hematology, Transfusion and Cell Therapy","volume":"46 ","pages":"Pages S284-S288"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140893086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}