National Journal glaucoma最新文献

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Spectacle correction in the complex of therapeutic measures for primary angle closure glaucoma. Preliminary report 眼科矫正在原发性闭角型青光眼综合治疗措施中的应用。初步报告
National Journal glaucoma Pub Date : 2022-03-14 DOI: 10.53432/2078-4104-2022-21-1-55-61
I. Gndoyan, A. V. Petrayevsky, N. Kuznetsova
{"title":"Spectacle correction in the complex of therapeutic measures for primary angle closure glaucoma. Preliminary report","authors":"I. Gndoyan, A. V. Petrayevsky, N. Kuznetsova","doi":"10.53432/2078-4104-2022-21-1-55-61","DOIUrl":"https://doi.org/10.53432/2078-4104-2022-21-1-55-61","url":null,"abstract":"PURPOSE. To improve the effectiveness of primary angle closure glaucoma (PACG) treatment in the initial stage in patients with hyperopia.MATERIAL AND METHODS. The study observed 18 patients (36 eyes) with the initial stage of PACG who also had low (8 subjects, 16 eyes) or moderate (10 subjects, 20 eyes) hyperopia. Study patients were divided into two groups: the main group — 12 patients (24 eyes) aged 43–67 years (mean age 55.6±1.1 years); the control group — 6 patients (12 eyes) aged 48–60 years (mean age 56.4±2.4 years). Prescribed treatment in the main group: selection and application of universal progressive correction, then laser iridecotomy (LIE) and management without pilocarpine instillations. Prescribed treatment in the control group: selection and application of monofocal correction for near vision, then LIE and instillations of 1% pilocarpine solution 3 times a day. All patients underwent visometry with correction, refractometry, ophthalmoscopy, tonometry, tonography, gonio-scopy, optical coherence tomography of the anterior eye segment, ultrasound biometry. Indicators of hydrodynamics and parameters of the anterior chamber were recorded before using spectacles correction, after the start of correction, after LIE, and 1 month after the start of all therapeutic measures.RESULTS. The use of progressive spectacle correction led to a significant decrease of true intraocular pressure (IOP) (p<0.001), an improvement of aqueous humor outflow (p<0.05) and an increase in the size of anterior chamber angle (p<0.001). Performing LIE in patients of the main group did not significantly change these indicators. The results obtained in this group made it possible to abandon the use of pilocarpine. In patients of the control group, the improvement in aqueous humor outflow (p<0.001) and increase in the size of anterior chamber angle (p<0.002) were more significant after LIE than after prescription of adequate monofocal correction for near vision (p<0.02–0.05 and p<0.2, respectively).CONCLUSION. The use of progressive spectacle correction in patients with hyperopia and initial stage of PACG before LIE leads to normalization of hydrodynamic parameters and an increase in the magnitude of anterior chamber angle without the use of miotic drugs. Prescription of progressive spectacle correction is advisable in these patients as a part of the complex of therapeutic measures aimed at normalizing ocular hydrodynamics.","PeriodicalId":129515,"journal":{"name":"National Journal glaucoma","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128144517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An effective model of clinical examination and monitoring of glaucoma patients 青光眼患者临床检查与监测的有效模式
National Journal glaucoma Pub Date : 2022-03-14 DOI: 10.53432/2078-4104-2022-21-1-71-78
D. A. Dorofeev, D. Baryshnikova, E. V. Kirilik, E. B. Parova
{"title":"An effective model of clinical examination and monitoring of glaucoma patients","authors":"D. A. Dorofeev, D. Baryshnikova, E. V. Kirilik, E. B. Parova","doi":"10.53432/2078-4104-2022-21-1-71-78","DOIUrl":"https://doi.org/10.53432/2078-4104-2022-21-1-71-78","url":null,"abstract":"Open-angle glaucoma is a chronic progressive optic neuropathy characterized by morphological changes in the optic nerve head and retinal nerve fibers layer in the absence of other eye diseases.Regular medical check-ups are necessary to assess the progression of glaucoma, to correct the treatment regimen or prescribe surgical interventions, to control the stabilization of the glaucoma process and to preserve visual functions for longer period. When planning the number of monitoring visits, it is necessary to carefully study the prognostic risk factors, since they are statistically associated with the development and progression of glaucoma. Closer observation of patients with glaucoma reduces the risk of irreversible changes in the organ of vision.Patient compliance is of particular importance in the progression of glaucoma. The adherence rate in the treatment of glaucoma is relatively lower compared to other chronic diseases that require lifelong treatment.Currently, there is no effective model of regular checkups for glaucoma patients, therefore this direction requires improvement and development, both in the standards and timing of patient examination, and in the use of remote methods of glaucoma control. The disadvantage of the current medical check-ups routine is the lack of individual approach to patients, lack of equipment in the offices of regional ophthalmologists, and lack of specialized glaucoma offices.The tense epidemiological situation during the Covid-19 pandemic, gave understanding that while in-person consultations and remote consultations (telemedicine) cannot replace each other, a combination of these methods is cost-effective, can reduce the uneven distribution of ophthalmic resources, reduce the burden on the doctor and the rate of misdiagnosis. The situation was aggravated by the closure of ophthalmological hospitals and an increase in the waiting time for consultation in higher specialized medical institutions, which probably entails an increase in patients with progression of the glaucomatous process and the economic burden on both the state and the patients themselves.Telemedicine should be gradually introduced into everyday practice, for which it is advisable to create a single database of glaucoma patients to track the glaucomatous process.","PeriodicalId":129515,"journal":{"name":"National Journal glaucoma","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127735549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Choroidal caverns in a patient with glaucoma (case study) 青光眼患者的脉络膜空洞(个案研究)
National Journal glaucoma Pub Date : 2022-03-14 DOI: 10.53432/2078-4104-2022-21-1-37-44
N. Kurysheva, O. A. Pererva, V. Kim, V. E. Kim
{"title":"Choroidal caverns in a patient with glaucoma (case study)","authors":"N. Kurysheva, O. A. Pererva, V. Kim, V. E. Kim","doi":"10.53432/2078-4104-2022-21-1-37-44","DOIUrl":"https://doi.org/10.53432/2078-4104-2022-21-1-37-44","url":null,"abstract":"The article describes a clinical case of the formation of a choroidal cavern (CC) in a patient with glaucoma. CC are associated with degenerative diseases of the retina, which is likely associated with dysfunction of the choriocapillaries and impaired retinal supply. Most often, СС are the outcome of pachychoroidal conditions and age-related macular degeneration. Patient D., 63 years old, with previously diagnosed primary open-angled glaucoma in the right eye, complained of a gradual decrease in visual acuity in that eye for several years. According to the examination, the cause of vision acuity decrease was determined as partial atrophy of the retinal layers associated with CC in the superior nasal part of the perifovea and fovea. Presumably, based on signs of a pachychoroidal state in both eyes of the patient, the formed CC is the outcome of chronic central serous chorioretinopathy: focal thickening of the choroid, vasodilatation of the Haller's layer, thinning of the choriocapillaris layer, the presence of pachychoroidal pigment epitheliopathy in the left eye. CC is the marker of choriocapillary blood flow deficiency, which is an unfavorable prognostic factor for the development of glaucoma — proved by glaucoma optic neuropathy being more advanced in the eye with CC compared to the contralateral eye.","PeriodicalId":129515,"journal":{"name":"National Journal glaucoma","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127201347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Studying the role of the choroid and lens in the development of primary anterior chamber angle closure 研究脉络膜和晶状体在原发性前房角闭合发展中的作用
National Journal glaucoma Pub Date : 2022-03-14 DOI: 10.53432/2078-4104-2022-21-1-3-13
N. Kurysheva, G. Sharova, E. I. Belikova
{"title":"Studying the role of the choroid and lens in the development of primary anterior chamber angle closure","authors":"N. Kurysheva, G. Sharova, E. I. Belikova","doi":"10.53432/2078-4104-2022-21-1-3-13","DOIUrl":"https://doi.org/10.53432/2078-4104-2022-21-1-3-13","url":null,"abstract":"PURPOSE. To study the role of the choroid and lens in the development of primary anterior chamber angle closure.MATERIAL AND METHODS. The study included 90 patients aged 47 to 80 years (30 with primary angle closure (PAC), 30 with suspected primary angle closure (PACs), and 30 in the control group) who underwent swept source optical coherence tomography (SS-OCT). The following parameters were analyzed: subfoveolar choroidal thickness (SFCT), intraocular pressure (IOP), axial length (AL), anterior chamber depth (ACD), lens vault (LV), iris curvature (ICurv) and iris thickness (IT750), angle opening distance (AOD500, AOD750), and trabecular-iris space area (TISA500, TISA750).RESULTS. SFCT in PAC (341±59 µm) and PACs (340±51 µm) was higher than in the control group (257.0±37.0 µm, p<0.05). In PAC and PACs, the correlations of SFCT with age, AL, LV, ICurv, IT750 were revealed (p<0.05 for each), as well as correlations of LV with age, IOP, ACD, ICurv, IT750, AOD500, AOD750, TISA500, TISA750 were found (p<0.05 for each). The correlation of SFCT with IOP was determined only in PAC (p=-0.476; p=0.008).CONCLUSION. The increase in the choroidal thickness in macula in both PACs and PAC compared with the controls, as well as the correlations of subfoveolar choroidal thickness with lens vault and iris parameters suggest the involvement of the choroid in the pathogenesis of primary angle closure disease (PACD). The correlations of lens vault with IOP, as well as the parameters of anterior chamber and iris indicate the prevailing role of the lens in the development of PACD and the need for its early replacement.","PeriodicalId":129515,"journal":{"name":"National Journal glaucoma","volume":"128 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134458270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Comparative assessment of the potential impact of chronic herpesvirus infection on intra- and postoperative complications in patients with glaucoma 慢性疱疹病毒感染对青光眼患者术中和术后并发症潜在影响的比较评估
National Journal glaucoma Pub Date : 2022-03-14 DOI: 10.53432/2078-4104-2022-21-1-46-53
V. Erichev, E. H. Abdullaeva, Y. Mazurova
{"title":"Comparative assessment of the potential impact of chronic herpesvirus infection on intra- and postoperative complications in patients with glaucoma","authors":"V. Erichev, E. H. Abdullaeva, Y. Mazurova","doi":"10.53432/2078-4104-2022-21-1-46-53","DOIUrl":"https://doi.org/10.53432/2078-4104-2022-21-1-46-53","url":null,"abstract":"PURPOSE. To evaluate the potential impact of herpesvirus infection (carriage) on early postoperative outcomes of antiglaucoma surgeries.MATERIAL AND METHODS. The study included 95 patients with stage I, II and III primary open-angle glaucoma (POAG), with indications for surgical treatment. The patients were divided into the main group (group 1, 31 patient) and the control group (group 2, 64 patients). The groups were formed on the basis of information obtained from the anamnesis about a transferred herpes simplex virus of any localization (as a rule, it was labial, oral-facial herpes and its skin manifestation). The indication for surgical treatment was the absence of persistent normalization of intraocular pressure and a decrease in visual functions. Depending on the clinical situation, patients underwent one of the two types of surgical interventions: trabeculectomy and non-penetrating deep sclerectomy. Analysis of postoperative complications was performed on day 7 after surgery.RESULTS. The most frequent complications in the early postoperative period were ciliochoroidal detachment, hyphema, increased intraocular pressure, shallow anterior chamber syndrome, excessive vascularization in the surgery site, clinical signs of conjunctival-scleral and sclerascleral scarring. On day 7 after antiglaucoma surgery, the IOP level was 9.1±0.8 mm Hg on average in the groups. IOP was 1–2 mm Hg higher in case of non-penetrating surgery. In the same patients, normalization of IOP by the same date was obtained in 63.15% of cases, which required goniopuncture; needling was indicated and performed in 84.2% of patients. Ciliochoroidal detachment was diagnosed in both groups with the same frequency: 9.7 and 9.4%, respectively. Presence of minor hyphema was observed only after trabeculectomy, in 16.1 and 10.9% of cases, respectively.CONCLUSION. Results of this study, firstly, do not indicate that HSV activates in response to surgical intervention; secondly, in patients who had been infected with it previously, only a tendency for the number of most common intra- and postoperative complications to increase was noted. The obtained results are insufficient for an unambiguous answer to the question posed in this study, which indicates the need for further research.","PeriodicalId":129515,"journal":{"name":"National Journal glaucoma","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126172308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficiency of brinzolamide and its combinations with timolol maleate in the treatment of primary open-angle glaucoma 布林唑胺联合马来酸替洛尔治疗原发性开角型青光眼的疗效观察
National Journal glaucoma Pub Date : 2021-09-20 DOI: 10.53432/2078-4104-2021-20-3-78-85
V. P. Fokin, S. V. Balalin, A. S. Balalin
{"title":"Efficiency of brinzolamide and its combinations with timolol maleate in the treatment of primary open-angle glaucoma","authors":"V. P. Fokin, S. V. Balalin, A. S. Balalin","doi":"10.53432/2078-4104-2021-20-3-78-85","DOIUrl":"https://doi.org/10.53432/2078-4104-2021-20-3-78-85","url":null,"abstract":"PURPOSE. To evaluate the effectiveness of 1% brinzolamide solution (Brineks-M) and its combination with 0.5% timolol maleate solution (Brinarga) in the treatment of patients with primary open-angle glaucoma (POAG).METHODS. The study involved 56 patients (56 eyes) with initial or moderate POAG and normal or moderately increased intraocular pressure. Individually tolerated IOP, hydrodynamic parameters, hemodynamic parameters of the eye (by computer ophthalmoplethysmography), microcirculation (by OCT angiography of the optic nerve head) were determined during the study.RESULTS. The hypotensive effect of 1% brinzolamide solution (Brineks-M) in patients with the early stage of POAG (23 eyes) after 3 months was 22.5%. The antihypertensive effect of Brinarga in patients with early and moderate stages of POAG (33 eyes) was 31.3% and persisted for 3 months of observation.CONCLUSION. A decrease in IOP to an individually tolerable level was accompanied by an improvement in ocular hemodynamics and microhemocirculation of the optic nerve head, and stabilization of visual functions in patients with POAG.","PeriodicalId":129515,"journal":{"name":"National Journal glaucoma","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115505544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
General ophthalmological aspects of the COVID-19 infection 一般眼科方面的COVID-19感染
National Journal glaucoma Pub Date : 2021-09-20 DOI: 10.53432/2078-4104-2021-20-3-102-108
E. K. Abdullaeva
{"title":"General ophthalmological aspects of the COVID-19 infection","authors":"E. K. Abdullaeva","doi":"10.53432/2078-4104-2021-20-3-102-108","DOIUrl":"https://doi.org/10.53432/2078-4104-2021-20-3-102-108","url":null,"abstract":"The COVID-19 pandemic has gone down in history as an international emergency that resulted in the death of millions of people. The coronavirus infection poses a large number of problems for medical science and, in particular, ophthalmology, which for the most part do not have obvious solutions. Due to insufficient knowledge about coronavirus infection in ophthalmology, there is a lack of understanding of eye symptoms, methods of prevention, treatment and organization of healthcare for such patients during a pandemic. Based on the available studies researching these issues, it is assumed that the virus may directly affect the ocular surface tissues (conjunctiva, cornea). Also, the possibility of transmission of infection through the ocular surface has not been ruled out. The data indicate the need to expand the measures for prevention of the spread of coronavirus infection, including through the surface of the eye.","PeriodicalId":129515,"journal":{"name":"National Journal glaucoma","volume":"150 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115590681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of repeated micropulse cyclophotocoagulation in patients with refractory glaucoma 反复微脉冲光凝治疗难治性青光眼的疗效评价
National Journal glaucoma Pub Date : 2021-09-20 DOI: 10.53432/2078-4104-2021-20-3-30-39
I. Ioshin, A. Tolchinskaya, I. Maksimov, A. V. Rakova, O. M. Potapova, A. L. Illarionova, I. A. Romanova, E. Smirnova
{"title":"Evaluation of repeated micropulse cyclophotocoagulation in patients with refractory glaucoma","authors":"I. Ioshin, A. Tolchinskaya, I. Maksimov, A. V. Rakova, O. M. Potapova, A. L. Illarionova, I. A. Romanova, E. Smirnova","doi":"10.53432/2078-4104-2021-20-3-30-39","DOIUrl":"https://doi.org/10.53432/2078-4104-2021-20-3-30-39","url":null,"abstract":"PURPOSE. To evaluate the efficacy and safety of repeated micropulse transscleral cyclophotocoagulation (MP-TSCPC) in patients with previously operated refractory glaucoma.MATERIALS AND METHODS. We examined 89 patients aged 74.2±7.3 years with moderate (16), advanced (58) and terminal (15) stages of uncompensated primary openangle glaucoma (POAG) before and within 12 months after the first MP-TSCPC (SUPRA 810, “Quantel Medical”, France) using standard laser parameters — 100 J. Indications for repeated MP-TSCPC were determined for 23 patients in 3 (1 patient), 6 (14 patients), 9 (8 patients) months after the first procedure. Repeated MP-TSCPC was carried out with higher impact energy — 125 J.RESULTS. After the first procedure, the hypotensive effect was achieved in 66 (74.2%) patients with refractory glaucoma lasting up to 12 months of follow-up. Repeated MP-TSCPC in 23 patients reduced the IOP by 31.2% in moderate, 31.8% in advanced, and 22.9% in terminal stages (p<0.05) by 6 months of follow-up. As a result, during 12 months of observation, MP-TSCPC (single and double) led to stabilization of the IOP in 83.1% of cases.CONCLUSION. Single and repeated micropulse TSCPC with laser energies of 100 J and 125 J is an effective and safe method of treating patients with refractory glaucoma. A single MP-TSCPC with laser energy of 100 J was effective in 66 (74.2%) patients by 12 months of observation, and single followed by repeated (laser energy of 125 J) — in 74 (83.1%) patients. It is possible to revise the basic parameters of the MP-TSCPC procedure from 100 to 125 J to achieve a longer and at the same time safe hypotensive effect in patients with refractory glaucoma.","PeriodicalId":129515,"journal":{"name":"National Journal glaucoma","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130909701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Analysis of changes in structural and hemodynamic parameters of the retina and foveolar avascular zone in patients with primary open-angle glaucoma and diabetes mellitus observed in long-term follow-up 长期随访观察原发性开角型青光眼合并糖尿病患者视网膜及小凹无血管带结构及血流动力学参数的变化
National Journal glaucoma Pub Date : 2021-09-20 DOI: 10.53432/2078-4104-2021-20-3-59-77
A. Fursova, Y. Gamza, O. Gusarevich, A. S. Derbeneva, M. V. Vasilyeva, N. V. Chubar, M. S. Tarasov
{"title":"Analysis of changes in structural and hemodynamic parameters of the retina and foveolar avascular zone in patients with primary open-angle glaucoma and diabetes mellitus observed in long-term follow-up","authors":"A. Fursova, Y. Gamza, O. Gusarevich, A. S. Derbeneva, M. V. Vasilyeva, N. V. Chubar, M. S. Tarasov","doi":"10.53432/2078-4104-2021-20-3-59-77","DOIUrl":"https://doi.org/10.53432/2078-4104-2021-20-3-59-77","url":null,"abstract":"PURPOSE. To study the changes in structural and hemodynamic parameters of the retina and foveolar avascular zone (FAZ) over time in patients with primary open-angle glaucoma (POAG) and diabetes mellitus (DM) observed in long-term follow-up.MATERIALS AND METHODS. The study included 258 patients (258 eyes) divided into five groups: group 1 — 58 patients (58 eyes) with stage I POAG and DM; group 2 — 50 patients (50 eyes) with stage I POAG; group 3 — 50 patients (50 eyes) with stage III POAG and DM; group 4 — 50 patients (50 eyes) with stage III POAG; group 5 — 50 patients (50 eyes) with DM. Patients underwent comprehensive ophthalmological examination, spectral domain optical coherence tomography (SD-OCT), optical coherence tomo-graphy angiography (OCT-A) of the macular region. The follow-up lasted 24 months.RESULTS. Analysis of the initial parameters in groups of patients with comorbidities showed the lowest values compared to controls, which were progressively worsening. MD in the group with DM + stage I POAG had reliably decreased after 12 months (by 5.05%), after 24 months by 12.12% (p≤0.05). The speed of GCL+IPL loss in groups 1 and 3 during the first year of observation was almost equal for initial and advanced glaucoma — 1.35 (-2.03%) and 1.32 (-2.36%) µm/year, but in group 3 the loss had doubled after two years (2.48 (-4.44%) and 1.41 (2.12%) µm/year). Deterioration of hymodynamic parameters in the macular region in groups 1 and 3 was noted primarily in the inner sectors (whole image vessel density in parafovea (PF wiVD) -0.79% during the first, and -2.57% during the second year in initial glaucoma, -0.6% and -1.24% in advanced, whole image vessel density in parafovea (PF wiVD) -0.2% and -1.22%, -0.66% and -1.56%, respectively). Parameters of FAZ had changed significantly after 2 years in patients with stage I POAG and DM: its area size had increased by 10.2%, perimeter by 4.49%, circularity index had decreased by 3.17%.CONCLUSION. Comorbidity of POAG and DM is accompanied by development and quick progression of significant changes in structural and hemodynamic parameters of the retina as observed by this long-term follow-up.","PeriodicalId":129515,"journal":{"name":"National Journal glaucoma","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125540441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative analysis of intraocular pressure dynamics after phacoemulsification with intraocular lens implantation in eyes with primary glaucoma 原发性青光眼超声乳化术与人工晶状体植入术后眼压动态的比较分析
National Journal glaucoma Pub Date : 2021-09-20 DOI: 10.53432/2078-4104-2021-20-3-49-57
A. Kolesnikov, E. V. Ban, M. A. Kolesnikova, L. V. Mironenko, A. I. Prozorova, A. E. Sevostyanov
{"title":"Comparative analysis of intraocular pressure dynamics after phacoemulsification with intraocular lens implantation in eyes with primary glaucoma","authors":"A. Kolesnikov, E. V. Ban, M. A. Kolesnikova, L. V. Mironenko, A. I. Prozorova, A. E. Sevostyanov","doi":"10.53432/2078-4104-2021-20-3-49-57","DOIUrl":"https://doi.org/10.53432/2078-4104-2021-20-3-49-57","url":null,"abstract":"PURPOSE. To conduct a comparative analysis of changes in intraocular pressure (IOP) after cataract phacoemulsification with implantation of intraocular lens (IOL) in comorbidity with primary open-angle (POAG) and primary closed-angle glaucoma (PACG).METHODS. The study analyzed the dynamics of IOP changes after cataract phacoemulsification in 65 patients (89 eyes) with comorbid PACG and 46 patients (58 eyes) with comorbid POAG, aged 50 to 92 years. Thirty-five (53.85%) patients with POAG had history of glaucoma surgery, and 12 (20.69%) patients with PACG had been treated with laser iridectomy. The disease was in the initial stage in 14.6% of POAG patients and 5.15% of PACG patients; moderate stage — in 55.05% and 47.19%, respectively; advanced stage — in 30.34% and 24.14%. Intraocular pressure in POAG was compensated in 84.5% and subcompensated in 15.5% of patients; in PACG it was compensated in 77.6%, subcompensated in 12.6%, and uncompensated in 10.4% of patients. Compensation of IOP was achieved either by previous surgeries, or application of local antihypertensive medications. Patients with subcompensated and elevated IOP received the maximum possible amount of hypotensive medications. The follow-up period ranged from 1 month to 2 years.RESULTS. Patients were divided into three groups according to postoperative IOP levels: the first group with IOP equal to preoperative level, the second group — with IOP below the initial level, and the third group with IOP above the initial level. The IOP levels were consistent with preoperative values at all follow-up periods in most of study patients, and after 2 years their portion exceeded 70%, while in POAG it was somewhat higher than in PACG (77.42% against 71.43%). The IOP below the preoperative level was observed in eyes with initial and moderate open-angle and closed-angle glaucoma, with the amount decreasing with longer follow-up (from 63.16% at 3 months to 16.13% after 2 years in POAG, and from 62.74% to 19.04% in PACG). In the early postoperative period, number of POAG and PACG patients in this group was comparable, but after 8 months it included more PACG patients. Elevation of IOP in both forms of glaucoma was most often observed in faradvanced stage in the early post-op period after phacoemulsification, subsequently their number decreased and by two years it decreased by almost twice (6.45% vs. 11.84% in POAG and 9.53% vs. 15.69% in PACG). During the entire follow-up period, the number of patients with ophthalmic hypertension in PACG was 30% higher than in POAG.CONCLUSION. The study showed that in most cases phacoemulsification has a stabilizing effect in patients with cataracts in combination with glaucoma. The hypotensive effect of the operation was observed in initial and advanced stages of glaucoma, when the drainage system of the eye was still preserved, and in the long term it was observed in a larger percentage of cases in angle-closure glaucoma compared to open-angle glaucoma. An increas","PeriodicalId":129515,"journal":{"name":"National Journal glaucoma","volume":"134 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122623665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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