{"title":"The importance of peer imitation on smoking initiation over time: a dynamical systems approach.","authors":"Carl Simon, David Mendez","doi":"10.1007/s10729-021-09583-z","DOIUrl":"10.1007/s10729-021-09583-z","url":null,"abstract":"<p><p>A recent Institute of Medicine Report calls for explicit modeling of smoking initiation, cessation and addiction processes. We introduce a model of smoking initiation that explicitly teases out the percentage of initiation due to social pressures, which we call \"peer-imitation,\" and the percentage due to other factors, such as media ads, family smoking, and psychological factors, which we call \"self-initiation.\" We propose a dynamic non-linear behavioral contagion model of smoking initiation and employ data from the National Survey on Drug Use and Health to estimate the relative contributions of imitation and self-initiation to the overall smoking initiation process. Although the percent of total smoking due to peer imitation has been trending downward over time, it remains higher than the percent due to self-initiation. We note unexpected changes for the 2007 cohort, and we discuss possible implications for intervention and for the spread of e-cigarettes.</p>","PeriodicalId":12903,"journal":{"name":"Health Care Management Science","volume":"25 2","pages":"222-236"},"PeriodicalIF":2.3,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9754948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Barlow, A. Morton, S. Dabak, Sven Engels, W. Isaranuwatchai, Y. Teerawattananon, K. Chalkidou
{"title":"What is the value of explicit priority setting for health interventions? A simulation study","authors":"E. Barlow, A. Morton, S. Dabak, Sven Engels, W. Isaranuwatchai, Y. Teerawattananon, K. Chalkidou","doi":"10.1007/s10729-022-09594-4","DOIUrl":"https://doi.org/10.1007/s10729-022-09594-4","url":null,"abstract":"","PeriodicalId":12903,"journal":{"name":"Health Care Management Science","volume":"25 1","pages":"460 - 483"},"PeriodicalIF":3.6,"publicationDate":"2022-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47391908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A multi-product multi-period stochastic model for a blood supply chain considering blood substitution and demand uncertainty","authors":"Yuan Xu, Joseph G. Szmerekovsky","doi":"10.1007/s10729-022-09593-5","DOIUrl":"https://doi.org/10.1007/s10729-022-09593-5","url":null,"abstract":"","PeriodicalId":12903,"journal":{"name":"Health Care Management Science","volume":"25 1","pages":"441 - 459"},"PeriodicalIF":3.6,"publicationDate":"2022-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45932906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Towards a more efficient healthcare system: Opportunities and challenges caused by hospital closures amid the COVID-19 pandemic","authors":"S. Saghafian, Lina Song, A. Raja","doi":"10.1007/s10729-022-09591-7","DOIUrl":"https://doi.org/10.1007/s10729-022-09591-7","url":null,"abstract":"","PeriodicalId":12903,"journal":{"name":"Health Care Management Science","volume":"25 1","pages":"187 - 190"},"PeriodicalIF":3.6,"publicationDate":"2022-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46174782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of correlation and false negatives in pool testing strategies for COVID-19.","authors":"Leonardo J Basso, Vicente Salinas, Denis Sauré, Charles Thraves, Natalia Yankovic","doi":"10.1007/s10729-021-09578-w","DOIUrl":"https://doi.org/10.1007/s10729-021-09578-w","url":null,"abstract":"<p><p>During the current COVID-19 pandemic, active testing has risen as a key component of many response strategies around the globe. Such strategies have a common denominator: the limited availability of diagnostic tests. In this context, pool testing strategies have emerged as a means to increase testing capacity. The efficiency gains obtained by using pool testing, derived from testing combined samples simultaneously, vary according to the spread of the SARS-CoV-2 virus in the population being tested. Motivated by the need for testing closed populations, such as long-term care facilities (LTCFs), where significant correlation in infections is expected, we develop a probabilistic model for settings where the test results are correlated, which we use to compute optimal pool sizes in the context of two-stage pool testing schemes. The proposed model incorporates the specificity and sensitivity of the test, which makes it possible to study the impact of these measures on both the expected number of tests required for diagnosing a population and the expected number and variance of false negatives. We use our experience implementing pool testing in LTCFs managed by SENAMA (Chile's National Service for the Elderly) to develop a simulation model of contagion dynamics inside LTCFs, which incorporates testing and quarantine policies implemented by SENAMA. We use this simulation to estimate the correlation of test results among collected samples when following SENAMA's testing guidelines. Our results show that correlation estimates are high in settings representative of LTCFs, which validates the use of the proposed model for incorporating correlation in determining optimal pool sizes for pool testing strategies. Generally, our results show that settings in which pool testing achieves efficiency gains, relative to individual testing, are likely to be found in practice. Moreover, the results show that incorporating correlation in the analysis of pool testing strategies both improves the expected efficiency and broadens the settings in which the technique is preferred over individual testing.</p>","PeriodicalId":12903,"journal":{"name":"Health Care Management Science","volume":"25 1","pages":"146-165"},"PeriodicalIF":3.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10729-021-09578-w","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39361862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abhishake Kundu, Felipe Feijoo, Diego A Martinez, Manuel Hermosilla, Timothy Matis
{"title":"Prospective adverse event risk evaluation in clinical trials.","authors":"Abhishake Kundu, Felipe Feijoo, Diego A Martinez, Manuel Hermosilla, Timothy Matis","doi":"10.1007/s10729-021-09584-y","DOIUrl":"https://doi.org/10.1007/s10729-021-09584-y","url":null,"abstract":"<p><p>Proactive and objective regulatory risk management of ongoing clinical trials is limited, especially when it involves the safety of the trial. We seek to prospectively evaluate the risk of facing adverse outcomes from standardized and routinely collected protocol data. We conducted a retrospective cohort study of 2860 Phase 2 and Phase 3 trials that were started and completed between 1993 and 2017 and documented in ClinicalTrials.gov. Adverse outcomes considered in our work include Serious or Non-Serious as per the ClinicalTrials.gov definition. Random-forest-based prediction models were created to determine a trial's risk of adverse outcomes based on protocol data that is available before the start of a trial enrollment. A trial's risk is defined by dichotomic (classification) and continuous (log-odds) risk scores. The classification-based prediction models had an area under the curve (AUC) ranging from 0.865 to 0.971 and the continuous-score based models indicate a rank correlation of 0.6-0.66 (with p-values < 0.001), thereby demonstrating improved identification of risk of adverse outcomes. Whereas related frameworks highlight the prediction benefits of incorporating data that is highly context-specific, our results indicate that Adverse Event (AE) risks can be reliably predicted through a framework of mild data requirements. We propose three potential applications in leading regulatory remits, highlighting opportunities to support regulatory oversight and informed consent decisions.</p>","PeriodicalId":12903,"journal":{"name":"Health Care Management Science","volume":"25 1","pages":"89-99"},"PeriodicalIF":3.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39445784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Majed Hadid, Adel Elomri, Tarek El Mekkawy, Laoucine Kerbache, Abdelfatteh El Omri, Halima El Omri, Ruba Y Taha, Anas Ahmad Hamad, Mohammed Hamad J Al Thani
{"title":"Bibliometric analysis of cancer care operations management: current status, developments, and future directions.","authors":"Majed Hadid, Adel Elomri, Tarek El Mekkawy, Laoucine Kerbache, Abdelfatteh El Omri, Halima El Omri, Ruba Y Taha, Anas Ahmad Hamad, Mohammed Hamad J Al Thani","doi":"10.1007/s10729-021-09585-x","DOIUrl":"https://doi.org/10.1007/s10729-021-09585-x","url":null,"abstract":"<p><p>Around the world, cancer care services are facing many operational challenges. Operations management research can provide important solutions to these challenges, from screening and diagnosis to treatment. In recent years, the growth in the number of papers published on cancer care operations management (CCOM) indicates that development has been fast. Within this context, the objective of this research was to understand the evolution of CCOM through a comprehensive study and an up-to-date bibliometric analysis of the literature. To achieve this aim, the Web of Science Core Collection database was used as the source of bibliographic records. The data-mining and quantitative tools in the software Biblioshiny were used to analyze CCOM articles published from 2010 to 2021. First, a historical analysis described CCOM research, the sources, and the subfields. Second, an analysis of keywords highlighted the significant developments in this field. Third, an analysis of research themes identified three main directions for future research in CCOM, which has 11 evolutionary paths. Finally, this paper discussed the gaps in CCOM research and the areas that require further investigation and development.</p>","PeriodicalId":12903,"journal":{"name":"Health Care Management Science","volume":"25 1","pages":"166-185"},"PeriodicalIF":3.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39895983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthias Grot, Tristan Becker, Pia Mareike Steenweg, Brigitte Werners
{"title":"Enhanced coverage by integrating site interdependencies in capacitated EMS location models.","authors":"Matthias Grot, Tristan Becker, Pia Mareike Steenweg, Brigitte Werners","doi":"10.1007/s10729-021-09562-4","DOIUrl":"https://doi.org/10.1007/s10729-021-09562-4","url":null,"abstract":"<p><p>In order to allocate limited resources in emergency medical services (EMS) networks, mathematical models are used to select sites and their capacities. Many existing standard models are based on simplifying assumptions, including site independency and a similar system-wide busyness of ambulances. In practice, when a site is busy, a call is forwarded to another site. Thus, the busyness of each site depends not only on the rate of calls in the surrounding area, but also on interactions with other facilities. If the demand varies across the urban area, assuming an average system-wide server busy fraction may lead to an overestimation of the actual coverage. We show that site interdependencies can be integrated into the well-known Maximum Expected Covering Location Problem (MEXCLP) by introducing an upper bound for the busyness of each site. We apply our new mathematical formulation to the case of a local EMS provider. To evaluate the solution quality, we use a discrete event simulation based on anonymized real-world call data. Results of our simulation-optimization approach indicate that the coverage can be improved in most cases by taking site interdependencies into account, leading to an improved ambulance allocation and a faster emergency care.</p>","PeriodicalId":12903,"journal":{"name":"Health Care Management Science","volume":"25 1","pages":"42-62"},"PeriodicalIF":3.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10729-021-09562-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39178933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Salma Makboul, Said Kharraja, Abderrahman Abbassi, Ahmed El Hilali Alaoui
{"title":"A two-stage robust optimization approach for the master surgical schedule problem under uncertainty considering downstream resources.","authors":"Salma Makboul, Said Kharraja, Abderrahman Abbassi, Ahmed El Hilali Alaoui","doi":"10.1007/s10729-021-09572-2","DOIUrl":"https://doi.org/10.1007/s10729-021-09572-2","url":null,"abstract":"<p><p>This paper addresses a planning decision for operating rooms (ORs) that aim at supporting hospital management. Focusing on elective patients, we determined the master surgical schedule (MSS) on a one-week time horizon. We assigned the specialties to available sessions and allocated surgeries to them while taking into consideration the priorities of the outpatients in the ambulatory surgical discipline. Surgeries were selected from the waiting lists according to their priorities. The proposed approach considered operating theater (OT) restrictions, patients' priorities and accounted for the availability of both intensive care unit (ICU) beds and post-surgery beds. Since the management decisions of hospitals are usually made in an uncertain environment, our approach considered the uncertainty of surgery duration and availability of ICU bed. Two robust optimization approaches that kept the model computationally tractable are described and applied to deal with uncertainty. Computational results based on a medium-sized French hospital archives have been presented to compare the robust models to the deterministic counterpart and to demonstrate the price of robustness.</p>","PeriodicalId":12903,"journal":{"name":"Health Care Management Science","volume":"25 1","pages":"63-88"},"PeriodicalIF":3.6,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s10729-021-09572-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39344433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}