Heart Asia最新文献_第6页

Prevalence of non-acute ischaemic cardiomyopathy in a Pakistani cohort. 巴基斯坦队列中的非急性缺血性心肌病患病率。

Heart Asia Pub Date : 2019-03-25 eCollection Date: 2019-01-01 DOI: 10.1136/heartasia-2018-011043

Muhammad Salman Ghazni, Saba Aijaz, Rehan Malik, Asad Z Pathan

{"title":"Prevalence of non-acute ischaemic cardiomyopathy in a Pakistani cohort.","authors":"Muhammad Salman Ghazni, Saba Aijaz, Rehan Malik, Asad Z Pathan","doi":"10.1136/heartasia-2018-011043","DOIUrl":"10.1136/heartasia-2018-011043","url":null,"abstract":"Heart failure with reduced left ventricular ejection fraction (HFrEF) is a frequently encountered clinical scenario. Coronary angiography (CAG) is usually performed to assess obstructive epicardial coronary artery disease (CAD) and the resultant ischaemia as causes of HFrEF.Objectives: To determine the frequency of obstructive CAD (OCAD) in patients with HFrEF and its independent predictors and outcomes.Methods: Retrospective observational study in Tabba Heart Institute on patients who underwent CAG during the past 4 years. Patients with prior known CAD or revascularisation were excluded. OCAD was defined as per the criteria from Felker et al. Regression modelling was performed to evaluate the predictors of OCAD. Survival was compared between the groups using the log rank test.Results: Out of 2235 patients who underwent CAG, 260 had HFrEF as a primary indication for CAG and, of these, 119 (45.8%) had OCAD. Major predictors of OCAD were age >50 years at presentation (OR 2.0, 95% CI 1.1 to 3.7), presence of chest pain (OR 4.3, 95% CI 2.3 to 8.1), family history of premature CAD (OR 2.8, 95% CI 1.3 to 5.9) and utilisation of non-invasive (NIV) stress testing before CAG (OR 3.6, 95% CI 1.8 to 7.1). Survival was significantly lower (log rank p<0.001) in patients with OCAD with no revascularisation compared with OCAD with revascularisation or those who had non-obstructive CAD, and the latter two groups had comparable survival.Conclusions: OCAD is detected in nearly half of the patients with reduced left ventricular systolic function undergoing CAG. Clinical judgement based on thorough history and use of NIV stress testing can help in appropriate patient selection for this test.","PeriodicalId":12858,"journal":{"name":"Heart Asia","volume":"11 1","pages":"e011043"},"PeriodicalIF":0.0,"publicationDate":"2019-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454328/pdf/heartasia-2018-011043.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37193667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of type and duration of training on the presence of an abnormal ECG in high-performance athletes. 训练类型和持续时间对高水平运动员异常心电图的影响。

Heart Asia Pub Date : 2019-03-19 eCollection Date: 2019-01-01 DOI: 10.1136/heartasia-2018-011120

Geoffrey Verrall, Angus Hains, Bronte Ayres, Richard Hillock

{"title":"Influence of type and duration of training on the presence of an abnormal ECG in high-performance athletes.","authors":"Geoffrey Verrall, Angus Hains, Bronte Ayres, Richard Hillock","doi":"10.1136/heartasia-2018-011120","DOIUrl":"https://doi.org/10.1136/heartasia-2018-011120","url":null,"abstract":"Objective: To undertake an ECG in high level athletes to determine the morphology of the ECG and to assess the influences on the ECG of the amount of time in a high-performance programme and the type of sport played.Design: Cross-sectional cohort study.Setting: High-performance sports programme.Interventions: Current symptoms (questionnaire) and length of time in a high-performance sports programme were recorded. Sports were classified as either high maximal oxygen uptake continuous, high maximal oxygen uptake repeated effort or static. An ECG was performed and classified by 2010 European Society of Cardiology guidelines into Groups 0 (normal), Group 1 (common and training-related ECG changes) and Group 2 (uncommon and training unrelated ECG changes).Results: The following were recorded: length of time in high performance sport programme (mean 2.3 years), type of sport (Continuous 103, Repeated effort 133, Static 37), ECG changes Group 0 (n=83, 31%), Group 1 (n=173, 63%) and Group 2 (n=17, 6.2%). Athletes with an increased length of time in a high performance programme demonstrated a higher likelihood of Group 2 ECG changes when compared with Groups 0 and 1 (p=0.05). The questionnaire did not help detect athletes with Group 2 ECG changes.Conclusions: This study demonstrates that an increased length of time in a high performance programme was associated with an increased number of detectable Group 2 ECG changes. Overall, the further investigation rate was 6.2%.","PeriodicalId":12858,"journal":{"name":"Heart Asia","volume":"11 1","pages":"e011120"},"PeriodicalIF":0.0,"publicationDate":"2019-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/heartasia-2018-011120","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37190105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The safety of morphine use in acute coronary syndrome: a meta-analysis. 急性冠脉综合征使用吗啡的安全性:一项荟萃分析。

Heart Asia Pub Date : 2019-03-19 eCollection Date: 2019-01-01 DOI: 10.1136/heartasia-2018-011142

Rugheed Ghadban, Tariq Enezate, Joshua Payne, Haytham Allaham, Ahmad Halawa, Hee Kong Fong, Obai Abdullah, Kul Aggarwal

{"title":"The safety of morphine use in acute coronary syndrome: a meta-analysis.","authors":"Rugheed Ghadban, Tariq Enezate, Joshua Payne, Haytham Allaham, Ahmad Halawa, Hee Kong Fong, Obai Abdullah, Kul Aggarwal","doi":"10.1136/heartasia-2018-011142","DOIUrl":"https://doi.org/10.1136/heartasia-2018-011142","url":null,"abstract":"Background: Morphine is widely used for pain control in patients with acute coronary syndrome (ACS). Several studies have questioned the safety of morphine in this setting with a concern of interaction with and reduced efficacy of antiplatelet agents.Objective: This study aims to systematically review the safety of morphine use in ACS.Methods: MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials were queried from inception through April 2018. Studies comparing morphine to nonmorphine use in ACS were included. Study endpoints included: in-hospital myocardial infarction (MI), all-cause mortality, stroke, major bleeding, minor bleeding and dyspnoea.Results: A total of 64 323 patients with ACS were included from eight studies, seven of which were observational studies and one was a randomised controlled trial. The use of morphine was associated with increased risk of in-hospital recurrent MI (OR 1.30, 95% CI 1.18 to 1.43, p < 0.00001). There was, however, no significant difference in terms of all-cause mortality (OR 0.87, 95% CI 0.62 to 1.22, p = 0.44), stroke (OR 0.81, 95% CI 0.39 to 1.66, p = 0.57), major bleeding (OR 0.49, 95% CI 0.24 to 1.00, p = 0.05), minor bleeding (OR 0.98, 95% CI 0.41 to 2.34, p = 0.97), or dyspnoea (OR 0.55, 95% CI 0.16 to 1.83, p = 0.33).Conclusion: The use of morphine for pain control in ACS was associated with an increased risk of in-hospital recurrent MI. Randomised clinical trials are needed to further investigate the safety of morphine in ACS.","PeriodicalId":12858,"journal":{"name":"Heart Asia","volume":"11 1","pages":"e011142"},"PeriodicalIF":0.0,"publicationDate":"2019-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/heartasia-2018-011142","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37190109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Nine contemporary therapeutic directions in heart failure. 当代心力衰竭的九个治疗方向。

Heart Asia Pub Date : 2019-03-08 eCollection Date: 2019-01-01 DOI: 10.1136/heartasia-2018-011150

Zaid Almarzooq, Manan Pareek, Lauren Sinnenberg, Muthiah Vaduganathan, Mandeep R Mehra

{"title":"Nine contemporary therapeutic directions in heart failure.","authors":"Zaid Almarzooq, Manan Pareek, Lauren Sinnenberg, Muthiah Vaduganathan, Mandeep R Mehra","doi":"10.1136/heartasia-2018-011150","DOIUrl":"https://doi.org/10.1136/heartasia-2018-011150","url":null,"abstract":"The global burden of heart failure has continued to increase dramatically with 26 million people affected and an estimated health expenditure of $31 billion worldwide. Several practice-influencing studies were reported recently, bringing advances along many frontiers in heart failure, particularly heart failure with reduced ejection fraction. In this article, we discuss nine distinct therapeutic areas that were significantly influenced by this scientific progress. These distinct areas include the emergence of sodium-glucose cotransporter-2 inhibitors, broadening the application of angiotensin-neprilysin inhibition, clinical considerations in therapy withdrawal in those patients with heart failure that ‘recover’ myocardial function, benefits of low-dose direct oral anticoagulants in sinus rhythm, targeted therapy for treating cardiac amyloidosis, usefulness of mitral valve repair in heart failure, the advent of newer left ventricular assist devices for advanced heart failure, the role of ablation in atrial fibrillation in heart failure, and finally the use of wearable defibrillators to address sudden death.","PeriodicalId":12858,"journal":{"name":"Heart Asia","volume":"11 1","pages":"e011150"},"PeriodicalIF":0.0,"publicationDate":"2019-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/heartasia-2018-011150","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37190526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Determinants of coronary artery disease risk factor management across three world regions. 三个世界地区冠状动脉疾病危险因素管理的决定因素。

Heart Asia Pub Date : 2019-03-08 eCollection Date: 2019-01-01 DOI: 10.1136/heartasia-2018-011112

Min Zhao, Ian Graham, Marie Therese Cooney, Diederick E Grobbee, Ilonca Vaartjes, Kerstin Klipstein-Grobusch

{"title":"Determinants of coronary artery disease risk factor management across three world regions.","authors":"Min Zhao, Ian Graham, Marie Therese Cooney, Diederick E Grobbee, Ilonca Vaartjes, Kerstin Klipstein-Grobusch","doi":"10.1136/heartasia-2018-011112","DOIUrl":"https://doi.org/10.1136/heartasia-2018-011112","url":null,"abstract":"Background: The SUrvey of Risk Factors (SURF) indicated poor control of risk factors in subjects with established coronary heart disease (CHD). The present study aimed to investigate determinants of risk factor management in patients with CHD.Methods and results: SURF recruited 9987 consecutive patients with CHD from Europe, Asia and the Middle East between 2012 and 2013. Risk factor management was summarised as a Cardiovascular Health Index Score (CHIS) based on six risk factor targets (non-smoker/ex-smoker, body mass index <30, adequate exercise, controlled blood pressure, controlled low-density lipoprotein and controlled glucose). Logistic regression models assessed the associations between determinants (age, sex, family history, cardiac rehabilitation, previous hospital admission and diabetes) and achievement of moderate CHIS (≥3 risk factors controlled). The results are presented as OR with corresponding 95% CI. A moderate CHIS was less likely to be reached by women (OR 0.90, 95% CI 0.69 to 1.00), those aged <55 years old (OR 0.62, 95% CI 0.53 to 0.76) and those with diabetes (OR 0.41, 95% CI 0.37 to 0.46). Attendance in cardiac rehabilitation was associated with better CHIS achievements (OR 1.62, 95% CI 1.42 to 1.87). Younger Asian and European patients had poorer risk factor management, whereas for patients from the Middle East age was not significantly associated with risk factor management. The availability and applicability of cardiac rehabilitation varied by region.Conclusions: Overall, risk factor management was poorer in women, those younger than 55 years old, those with diabetes and those who did not participate in a cardiac rehabilitation. Determinants of cardiovascular risk factor management differed by region.","PeriodicalId":12858,"journal":{"name":"Heart Asia","volume":"11 1","pages":"e011112"},"PeriodicalIF":0.0,"publicationDate":"2019-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/heartasia-2018-011112","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37190103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Outcomes of patients with heart failure after primary prevention ICD unit generator replacement. 一级预防性ICD单元发生器置换术后心力衰竭患者的预后。

Heart Asia Pub Date : 2019-02-28 DOI: 10.1136/heartasia-2018-011162

Khang-Li Looi, Andrew Gavin, Lisa Cooper, Liane Dawson, Debbie Slipper, Nigel Lever

{"title":"Outcomes of patients with heart failure after primary prevention ICD unit generator replacement.","authors":"Khang-Li Looi, Andrew Gavin, Lisa Cooper, Liane Dawson, Debbie Slipper, Nigel Lever","doi":"10.1136/heartasia-2018-011162","DOIUrl":"10.1136/heartasia-2018-011162","url":null,"abstract":"Objective: Data describing outcomes after implantable cardioverter-defibrillator (ICD) unit generator replacement in patients with heart failure (HF) with primary prevention devices are limited.Method: Data on patients with HF who underwent primary prevention ICD/cardiac resynchronisation therapy-defibrillator (CRT-D) implantation from 2007 until mid-2015 who subsequently received unit generator replacement were analysed. Outcomes assessed were mortality, appropriate ICD therapy and shock, and procedural complications.Results: 61 of 385 patients with HF with primary prevention ICD/CRT-D undergoing unit generator replacement were identified. Follow-up period was 1.8±1.5 years after replacement. 43 (70.5%) patients had not received prior appropriate ICD therapy prior to unit replacement. The cumulative risks of appropriate ICD therapy at 1, 3 and 5 years after unit replacement in those without prior ICD therapy were 0%, 6.2% and 50% compared with 6.2%, 59.8% and 86.6%, respectively (p=0.005) in those with prior ICD therapies. No predictive factors associated with appropriate ICD therapy after replacement could be identified. 41 (32.8%) patients no longer met guideline indications at the time of unit replacement but risks of subsequent appropriate ICD interventions were not different compared with those who continued to meet primary prevention ICD indications.The 5-year mortality risk after unit replacement was 18.4% and there were high procedural complication rates (9.8%).Conclusion: No predictive marker successfully stratified patients no longer needing ICD support prospectively. Finding such a marker is important in decision-making about device replacement particularly given the concerns about the complication rates. These factors should be considered at the time of ICD unit replacement.","PeriodicalId":12858,"journal":{"name":"Heart Asia","volume":"11 1","pages":"e011162"},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/heartasia-2018-011162","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37190527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Twenty-five-year-old woman with palpitations and hypertrophic cardiomyopathy. 25岁女性，心悸和肥厚性心肌病。

Heart Asia Pub Date : 2019-02-23 eCollection Date: 2019-01-01 DOI: 10.1136/heartasia-2018-011174

Krittapoom Akrawinthawong, Vineet Kumar

引用次数: 1

Knowledge of risk factors for hypertension in a rural Indian population. 对印度农村人群高血压危险因素的了解。

Heart Asia Pub Date : 2019-02-23 eCollection Date: 2019-01-01 DOI: 10.1136/heartasia-2018-011136

Doreen Busingye, Simin Arabshahi, Roger G Evans, Michaela A Riddell, Velandai K Srikanth, Kamakshi Kartik, Kartik Kalyanram, Xuan Zhu, Oduru Suresh, George Howard, Amanda G Thrift

{"title":"Knowledge of risk factors for hypertension in a rural Indian population.","authors":"Doreen Busingye, Simin Arabshahi, Roger G Evans, Michaela A Riddell, Velandai K Srikanth, Kamakshi Kartik, Kartik Kalyanram, Xuan Zhu, Oduru Suresh, George Howard, Amanda G Thrift","doi":"10.1136/heartasia-2018-011136","DOIUrl":"https://doi.org/10.1136/heartasia-2018-011136","url":null,"abstract":"Objective: To study knowledge of risk factors and consequences of hypertension in a rural population in South India.Methods: This is a community-based study conducted among adults of a rural population in the Rishi Valley, India. Residents of randomised rural villages were invited to participate in a study of hypertension. We obtained measures of blood pressure, height, weight, waist and hip circumferences and questionnaire-based information on knowledge about hypertension, sociodemographic characteristics and health behaviours. Multivariable logistic regression analyses were conducted to determine the factors associated with knowledge of risk factors for hypertension (knowledge of ≥2 risk factors).Results: The study comprised 641 adults; 132 aware and 218 unaware of their hypertension, and 291 with normal blood pressure. Only 31% of participants knew that hypertension adversely affects an individual's health and 7% knew the benefits of treating hypertension. Almost a third (30%) of those aware of their hypertensive status, and 48% overall, did not know any of the risk factors for hypertension. Being aware of one's hypertensive status (OR 2.51, 95% CI 1.44 to 4.39), being treated for hypertension, male sex, younger age, having some schooling, abdominal obesity and physical inactivity were associated with better knowledge of risk factors for hypertension.Conclusion: Knowledge of risk factors and consequences of hypertension in this disadvantaged population was poor. There was better knowledge of risk factors in some, but not all, people who were aware of having hypertension. Screening and targeted educational programmes are warranted in this population to improve health behaviours and reduce the consequences of hypertension.","PeriodicalId":12858,"journal":{"name":"Heart Asia","volume":"11 1","pages":"e011136"},"PeriodicalIF":0.0,"publicationDate":"2019-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/heartasia-2018-011136","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37190108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Peculiar mechanical complication of myocardial infarction. 心肌梗塞的特殊机械并发症。

Heart Asia Pub Date : 2019-02-23 eCollection Date: 2019-01-01 DOI: 10.1136/heartasia-2018-011156

Pratheesh George Mathen, Gopal Chandra Ghosh, Viji Samuel Thomson

{"title":"Peculiar mechanical complication of myocardial infarction.","authors":"Pratheesh George Mathen, Gopal Chandra Ghosh, Viji Samuel Thomson","doi":"10.1136/heartasia-2018-011156","DOIUrl":"https://doi.org/10.1136/heartasia-2018-011156","url":null,"abstract":"A 58-year-old man presented to the chest pain unit with crescendo angina over 24 hours and worsening dyspnoea of 10 hours duration. He was a known diabetic and hypertensive on regular treatment for 10 years and a habitual smoker with over 15 pack-years smoking duration. Examination revealed a profusely diaphoretic and dyspnoeic (respiratory rate of 45/min) individual with a blood pressure of 100/60 mm Hg and heart rate of 124 beats/min. He was hypoxic and his oxygen saturation in the ambient air was 64%. His jugular venous pressure was elevated with a prominent V wave. Cardiovascular examination revealed a harsh grade IV/VI systolic murmur over the lower left parasternal border. There were bilateral extensive crepitations heard over the lung fields. ECG on admission revealed presence of Q wave and ST elevation in leads II and III, aVF with ST depression in I and aVL. X-ray chest showed normal cardiac shadow and features of grade III pulmonary venous hypertension. Transthoracic echocardiography is shown in figure 1.Figure 1Transthoracic echocardiogram short axis view at mid cavity level, 2D (A) and colour Doppler (B) image.Question: What is the most likely diagnosis?A. Left ventricular (LV) true aneurysmB. LV pseudoaneurysmC. LV pseudo-pseudoaneurysmD. Ventricular septal rupture (VSR)E. LV free wall rupture.","PeriodicalId":12858,"journal":{"name":"Heart Asia","volume":"11 1","pages":"e011156"},"PeriodicalIF":0.0,"publicationDate":"2019-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/heartasia-2018-011156","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37190110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Managing hypertension in 2018: which guideline to follow? 2018年高血压管理:遵循哪个指南?

Heart Asia Pub Date : 2019-02-22 eCollection Date: 2019-01-01 DOI: 10.1136/heartasia-2018-011127

Fabio Angeli, Gianpaolo Reboldi, Monica Trapasso, Adolfo Aita, Paolo Verdecchia

{"title":"Managing hypertension in 2018: which guideline to follow?","authors":"Fabio Angeli, Gianpaolo Reboldi, Monica Trapasso, Adolfo Aita, Paolo Verdecchia","doi":"10.1136/heartasia-2018-011127","DOIUrl":"https://doi.org/10.1136/heartasia-2018-011127","url":null,"abstract":"Hypertension is a global public health issue and a major cause of morbidity and mortality. Its prevalence is increasing in many Asian countries, with a number of countries with blood pressure above the global average. Although the average systolic blood pressure is decreasing worldwide since the 1980s at the rate of about 1 mm Hg systolic blood pressure per decade, it is increasing in low-income and middle-income countries, especially in the East and South Asian population. Of note, the much larger base Asian population results in a considerably larger absolute number of individuals affected. When compared with Western countries, hypertension among Asian populations has unique features in terms of its onset, clustering of associated cardiovascular risk factors, complications and outcomes. Moreover, only a minority of hypertensive individuals are receiving treatment and achieving control. Projected number of deaths related to hypertension dramatically increased in the last 25 years in some Asian regions with a disproportionately high mortality and morbidity from stroke compared with Western countries. The relation between blood pressure and the risk of stroke is stronger in Asia than in Western regions. Although new Guidelines for hypertension diagnosis and management have been recently released from Europe and North America, the unique features of Asian hypertensive patients raise concerns on the clinical applicability of Western Guidelines to Asian populations. To this purpose, we critically reviewed key elements from the most updated Guidelines. We also discussed their core concepts to verify the impact on hypertension prevention and management in Asian countries.","PeriodicalId":12858,"journal":{"name":"Heart Asia","volume":"11 1","pages":"e011127"},"PeriodicalIF":0.0,"publicationDate":"2019-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/heartasia-2018-011127","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37190106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14