{"title":"[Current management of the HELLP syndrome].","authors":"C Bartz, W Rath","doi":"10.1159/000107262","DOIUrl":"https://doi.org/10.1159/000107262","url":null,"abstract":"<p><p>The HELLP syndrome as part of the microangiopathic syndromes requires special attention in terms of a rapid and accurate diagnostic and differential diagnostic workup because of its possibly rapid clinical deterioration. It is defined by the classical triad of hemolysis,elevated liver enzymes and low platelet counts which may lead to prognostically relevant problems in differentiating it from thrombotic-thrombocytopenic purpura and hemolytic-uremic syndrome and other pregnancy-related and unrelated liver diseases, i.e. mainly clinical and laboratory similarities to other liver diseases such as acute fatty liver or intrahepatic cholestasis in pregnancy or pregnancy-unrelated settings like viral hepatitides. The management in the different phases of pregnancy is described in detail. Therapeutic options to prolong pregnancy are discussed as are the possibilities of prophylaxis in subsequent pregnancies and aspects of the followup.</p>","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"47 4","pages":"215-21"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000107262","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27029247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Psychosomatic aspects of endometriosis--current state of scientific knowledge and clinical experience].","authors":"B Leeners, B Imthurn","doi":"10.1159/000102575","DOIUrl":"https://doi.org/10.1159/000102575","url":null,"abstract":"<p><p>Current therapeutic options allow successful treatment in only part of the women presenting with endometriosis. Pain, fatigue/exhaustion, intensive and repeated therapies as well as a concentration on the disease lead to a variety of consequences concerning education/ profession, body perception, self-esteem, partnership/social contacts, sexuality and psychic well-being. Difficulties in becoming pregnant represent a further central problem in dealing with endometriosis. Therefore, biopsychosocial aspects should be integrated into current somatically oriented models of medical support.</p>","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"47 3","pages":"132-9"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000102575","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26837586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advancing women's cancer care: highlights from the Annual Meeting on Women's Cancer 2007. Report on the 38th Annual Meeting of the Society of Gynecologic Oncologists, San Diego, Calif., March 3-7, 2007.","authors":"Patrick Petignat, Walter Gotlieb","doi":"10.1159/000107266","DOIUrl":"https://doi.org/10.1159/000107266","url":null,"abstract":"Importance of Specialist Care and Centralization for Ovarian Cancer Patients It is not a new concept that ovarian cancer patients benefit from being treated in centers with large numbers of patients. Nevertheless, Dr. John Chan from Standford University (abstract 17) reported one of the largest published series. They retrospectively evaluated the outcome of nearly 1,500 women (stage IC–IV) treated by a gynecologic oncologist or a physician other than a gynecologic oncologist. The 5-year survival rate was 39% for those treated by specialists and 30% for the other group; the difference was statistically significant at p ! 0.001. In multivariate analysis, patients who were treated by a specialist were significantly more likely to be more affluent, live in urban regions and have a better education.","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"47 4","pages":"240-2"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000107266","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27029251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frank Oehmke, Christina Deisting, Hans-Rudolf Tinneberg
{"title":"[Conservative therapy of endometriosis].","authors":"Frank Oehmke, Christina Deisting, Hans-Rudolf Tinneberg","doi":"10.1159/000102573","DOIUrl":"https://doi.org/10.1159/000102573","url":null,"abstract":"<p><p>Endometriosis is the second most frequent benign disease of the female of reproductive age. In spite of extensive research, the etiology of this disease is still largely enigmatic. A causal therapy has not been found yet. Several drug therapy approaches are available but none offers a permanent cure of endometriosis. In addition, the range of side effects of the particular drug therapies has to be considered individually. The treatment of patients with endometriosis cannot be standardized but has to differentiate the individual factors and life circumstances of the patients.</p>","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"47 3","pages":"118-23"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000102573","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26837584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Endometriosis--a frequently underestimated disease].","authors":"D Fink, U Lang, R Kimmig","doi":"10.1159/000102571","DOIUrl":"https://doi.org/10.1159/000102571","url":null,"abstract":"<p><p>Endometriosis is one of the most frequent gynecological disorders. The diagnosis is usually confirmed by laparoscopy. As the etiology and pathogenesis of endometriosis are still mostly obscure, a causal therapy has not been found yet. As for the medicinal treatment of endometriosis, all modern therapeutic approaches aim at ovarian downregulation or at antagonizing the estrogen effects in the endometriosis focus. Surgery aims at a preferably complete resection of all endometriosis focuses. In addition to individual distress, the economic aspect must not be neglected because of its high morbidity, loss of workforce and the repeated therapeutic interventions. As treatment strongly depends on the specific complaints and the personal life circumstances of the patient, an individual therapy concept should always be considered.</p>","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"47 3","pages":"111-2"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000102571","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26837582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Giving birth in the water: experience after 1,825 water deliveries. Retrospective descriptive comparison of water birth and traditional delivery methods].","authors":"A Thöni, N Zech, F Ploner","doi":"10.1159/000100336","DOIUrl":"https://doi.org/10.1159/000100336","url":null,"abstract":"<p><strong>Objective: </strong>We reviewed 1,825 water births at a single institution over a 9-year period.</p><p><strong>Methods: </strong>We compared 830 primipara deliveries in water with 424 primipara deliveries in the traditional bed and 136 on the delivery stool. We also evaluated the duration of labour, arterial cord blood pH and base excess in the primiparae, and perineal trauma, shoulder dystocia and deliveries after preceding caesarean section as well as rates of neonatal infection in all the 1,825 water births.</p><p><strong>Results: </strong>The duration of the first stage of labour was significantly shorter with water births than with the other delivery positions. The episiotomy rate for all water births was found to be much lower compared to deliveries carried out in the bed or on the birthing stool. The rate of perineal tears was similar. There were no differences in the duration of the second stage, arterial cord blood pH and base excess. No woman using the water birth method required analgesics. There were 3 shoulder dystocias with water births. Sixty-eight women delivered in water after a preceding caesarean section.</p><p><strong>Conclusion: </strong>Water births appears to be associated with a significantly shorter first stage of labour, a lower episiotomy rate and reduced analgesic requirements when compared with other delivery positions. If women are selected appropriately, water birth appears to be safe for both the mother and neonate.</p>","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"47 2","pages":"76-80"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000100336","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26671437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Multiple pregnancies--Part 2].","authors":"U Lang, D Fink, R Kimmig","doi":"10.1159/000100332","DOIUrl":"https://doi.org/10.1159/000100332","url":null,"abstract":"<p><p>Increasing rates of multiple pregnancies with ensuing clinical problems such as prematurity, fetal growth disorders and specific disorders of multiple pregnancies are a challenge for providers of prenatal care and delivery. In general clinical and scientific data regarding prenatal care (e.g. use of tocolytics) and birth surveillance (e.g. mode of delivery) are less abundant and valid for multiple pregnancies than for singleton pregnancies. This is why in particular prematurity and supervision of birth are discussed in the following articles. Obviously there is need for multidisciplinary prospective multicenter studies on various problems of multiple pregnancies.</p>","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"47 2","pages":"55-6"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000100332","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26671534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O Shebl, T Ebner, M Sommergruber, A Sir, W Urdl, G Tews
{"title":"[Multiple pregnancies after ART: problems and possible solutions].","authors":"O Shebl, T Ebner, M Sommergruber, A Sir, W Urdl, G Tews","doi":"10.1159/000098119","DOIUrl":"https://doi.org/10.1159/000098119","url":null,"abstract":"<p><p>Multiple pregnancies following an assisted reproduction technique (ART) should be seen as a complication, and for that reason they should be avoided. In contrast to singleton pregnancies following ART, the multiple pregnancies are associated with a higher prenatal, neonatal and maternal risk; furthermore this results in a financial burden for the health care system. This paper gives an overview of the latest literature and different attempts of European countries, trying to reduce the multiple pregnancy rate. An efficient reduction is only possible by single-embryo transfers. There should be strict and cross-national regulation for the choice of women who should have a transfer of more than one embryo.</p>","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"47 1","pages":"3-8"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000098119","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26529762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Obstetrical care of multiple pregnancies up to the 24th week of pregnancy--a survey].","authors":"Martin Haeusler","doi":"10.1159/000098121","DOIUrl":"https://doi.org/10.1159/000098121","url":null,"abstract":"<p><p>The number of multiple pregnancies increases, as does the knowledge of their (patho)physiology, and of diagnostic and therapeutic difficulties. The role of sonography in prenatal medicine has developed dramatically over the years, especially in assessing and treating fetuses in multiple pregnancies. Therefore this article reflects this development. It gives an overview of the current knowledge and literature.</p>","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"47 1","pages":"14-22"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000098121","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26530263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Primary malignant melanoma of the vagina--case report and review of the literature].","authors":"C Betschart, S von Orelli, D Mihic, D Fink","doi":"10.1159/000098124","DOIUrl":"https://doi.org/10.1159/000098124","url":null,"abstract":"<p><p>The primary malignant melanoma of the vagina is a very rare tumor with less than 300 cases reported worldwide. Metastatic melanomas of the vagina are even rarer and only 5 cases have been reported so far. We describe the case of patient with a melanoma of the left side of the vagina with a tumor size of 6 cm and a tumor invasion of 2.5 cm. At the time of diagnosis there were no signs of nodal metastases in the positron emission tomography. In the literature, wide local excision with adjuvant radiotherapy is recommended, and radical surgery with adjuvant radiotherapy as second-line therapy. Both procedures show similar 5-year survival rates. To reduce the risk of metastases, we had planned an immunotherapy with interferon-alpha, which has been shown to improve relapse-free and overall survival in patients with high-risk cutaneous melanoma. Unfortunately, the cancer was found to have heavily metastasized 6 months later; the patient therefore received a palliative chemotherapy with dacarbazine and thalidomide.</p>","PeriodicalId":12827,"journal":{"name":"Gynakologisch-geburtshilfliche Rundschau","volume":"47 1","pages":"39-44"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000098124","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26530265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}