GSC Advanced Research and Reviews最新文献

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Analyzing the financial viability and technical efficiency of aquaculture farming in Delta State, Nigeria: Lessons from cluster operations 分析尼日利亚三角洲州水产养殖业的财务可行性和技术效率:从集群运作中汲取的经验教训
GSC Advanced Research and Reviews Pub Date : 2024-03-30 DOI: 10.30574/gscarr.2024.18.3.0107
Sarah ENWA, Ovuevuraye Dicta OGISI, Felix Odemero ACHOJA
{"title":"Analyzing the financial viability and technical efficiency of aquaculture farming in Delta State, Nigeria: Lessons from cluster operations","authors":"Sarah ENWA, Ovuevuraye Dicta OGISI, Felix Odemero ACHOJA","doi":"10.30574/gscarr.2024.18.3.0107","DOIUrl":"https://doi.org/10.30574/gscarr.2024.18.3.0107","url":null,"abstract":"This study delved into the comprehensive analysis of aquaculture farming in Delta State, specifically focusing on the financial viability and technical efficiency of cluster operations. As aquaculture plays a crucial in meeting global seafood demands, understanding the dynamics at the regional level become imperative. The study employed a multifaceted approach to assess the financial viability of aquaculture farming, technical efficiency of aquaculture production. By adopting a cluster based perspective, the research aims to unravel the intricacies of collaborative farming operations, identifying synergies that contribute to enhanced financial outcome. Insights garnered from this financial evaluation can provide stakeholders with strategic guidance for sustainable economic practices within the aquaculture sector. The research draws on a diverse set of data source, including financial records, production metrics, focus group discussions and questionnaire distributions. Statistical tools and econometric models are applied to quantify the relationships between various variables, providing a clear understanding of the factors influencing technical efficiency and financial Findings from this study showed that the price of labour, price of fish feeds and price of medicine had a significant effect on efficiency of aqua farming with a coefficient of 0.5468**,-0.7862**, -0.8896** respectively. The result of the technical efficiency , (25.0%) falls within the 0.71 - 0.8 range, indicating a high level of technical efficiency of aqua farmers. This is followed by those in the 0.31 - 0.4 and 0.51 - 0.6 ranges, each with 11.2% of farmers. In contrast. The result of the BCR showed a significant variation in profitability highlights of aqua farming operations in the study area are more financially rewarding, with a net return on investment (ROI) of 0.58. However, the technical efficiencies and productivities of aqua farmers in clusters were significantly high regardless of how biases were corrected, implying that participation in cluster group is positively related to increases in aqua farmers output.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"22 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140362021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modified agricultural waste adsorbent for zinc ions removal from aqueous solution: Equilibrium, kinetics, and thermodynamics investigation 从水溶液中去除锌离子的改性农业废弃物吸附剂:平衡学、动力学和热力学研究
GSC Advanced Research and Reviews Pub Date : 2024-03-30 DOI: 10.30574/gscarr.2024.18.3.0108
F. Abouzeid
{"title":"Modified agricultural waste adsorbent for zinc ions removal from aqueous solution: Equilibrium, kinetics, and thermodynamics investigation","authors":"F. Abouzeid","doi":"10.30574/gscarr.2024.18.3.0108","DOIUrl":"https://doi.org/10.30574/gscarr.2024.18.3.0108","url":null,"abstract":"The current research signifies potential bio sorbent (banana and Pomegranate peel) With a view for zinc ions adsorption as of aqueous solution. Mass, zinc ion concentration, pH, time, and temperature parameters were examined. The highly beneficial requirements for zinc ion adsorption are 10 ppm as preliminary concentration, 0.21 g as pomegranate and banana rinds dosage and 5.5, 5.23 as pH for banana and Pomegranate rind. Elimination results follow the Langmuir replica with qmax of 25.64 mg/g for banana and 41.66 mg/g for Pomegranate rind. The elimination process kinetic was equipped well via second -order equivalence. It was examined that the zinc ion adsorption procedure on both bio sorbents is instinctive procedure, endothermal for banana and pomegranate rind. A distinctive enhancement in the adsorptive shell was observed once the adsorption procedure that revealed through scanning electron microscope.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"50 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140363443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Salinity tolerance at the germination stage of Senegalese varieties of peanut, cowpea, millet and sorghum 塞内加尔花生、豇豆、小米和高粱品种发芽阶段的耐盐性
GSC Advanced Research and Reviews Pub Date : 2024-03-30 DOI: 10.30574/gscarr.2024.18.3.0091
Adiouma Dangue, Mame Arama, Fall Ndiaye, Malick Ndiaye, Malamine Manga
{"title":"Salinity tolerance at the germination stage of Senegalese varieties of peanut, cowpea, millet and sorghum","authors":"Adiouma Dangue, Mame Arama, Fall Ndiaye, Malick Ndiaye, Malamine Manga","doi":"10.30574/gscarr.2024.18.3.0091","DOIUrl":"https://doi.org/10.30574/gscarr.2024.18.3.0091","url":null,"abstract":"Salinization continues to increase in semi-arid areas like Senegal where it limits seed germination, a crucial phase in a plant's cycle. Adaptation to salinization, one of the great challenges of modern agriculture, is possible through the use of halotolerant varieties which could be selected early during seed germination. The general objective of this study is to evaluate the effect of salinity on the germination of peanut, cowpea, millet and sorghum. The effect of NaCl (0, 40, 80 and 120 mM) was tested on seed germination for one week at 30°C in a culture chamber. The parameters evaluated are: the final percentage of germination (FG), the germination vigor index (GVI), the coefficient of velocity of germination (CVG), the percentage reduction in germination compared to the control (PRG) and the daily average germination (DAG). The FG, GVI and CVG of millet, cowpea, sorghum and peanut show significant differences (p<0.01) for each NaCl concentration. On the other hand, DAG and PRG give significant differences only at 80 mM and/or 120 mM NaCl. FG, CVG, DAG and GVI decreased with increasing salinity for all varieties unlike PRG. Cowpea (V4) are less sensitive to salinity than peanut (V3), which tolerate NaCl better than cereals. Millet (V5) is more resistant than sorghum (V7). The increase in NaCl led to a significant difference in germination. Cowpea (V4) would be more osmotolerant than peanut (V3) which is more tolerant than cereals such as millet (V5) and sorghum (V7) to salinity. These varieties would be the most recommended for successful cultivation in a saline environment.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"4 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140364558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comprehensive survey of performance, security and privacy issues in the network interface layer of the TCP/IP 对 TCP/IP 网络接口层的性能、安全和隐私问题的全面调查
GSC Advanced Research and Reviews Pub Date : 2024-03-30 DOI: 10.30574/gscarr.2024.18.3.0112
Emmanuel Asituha
{"title":"A comprehensive survey of performance, security and privacy issues in the network interface layer of the TCP/IP","authors":"Emmanuel Asituha","doi":"10.30574/gscarr.2024.18.3.0112","DOIUrl":"https://doi.org/10.30574/gscarr.2024.18.3.0112","url":null,"abstract":"The network interface layer of the TCP/IP protocol suite, primarily comprised of the Internet Protocol (IP), serves as the backbone of modern internet communication. With its efficient data delivery, The network interface layer, presents key challenges in terms of performance, security, and privacy. This comprehensive survey delves into these three crucial aspects, analyzing the inherent vulnerabilities, limitations of the interface layer, and provide solutions of the related problems. The performance analysis explores throughput, latency, and bandwidth constraints, along with solutions such as bandwidth allocation and optimization techniques. Vulnerabilities within Network Interface Layer, including denial-of-service attacks and MAC address spoofing, are discussed, along with a review of existing security mechanisms. Privacy flaws are examined, covering MAC address tracking, profiling risks, and anonymization techniques, while also addressing privacy considerations on the Internet of Things. The survey analyzes several case studies providing comparative analysis of the network interface layer protocols, with support of the real world scenarios including performance analysis in high density environment, and security and privacy risks in smart homes networks. The findings provide a comprehensive understanding of the complexities surrounding performance, security, and privacy issues future directions and potential solutions.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140363909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing the role of LNG in global carbon neutrality efforts: A project management review 评估液化天然气在全球碳中和努力中的作用:项目管理回顾
GSC Advanced Research and Reviews Pub Date : 2024-03-30 DOI: 10.30574/gscarr.2024.18.3.0095
Ifeanyi Onyedika Ekemezie, Wags Numoipiri Digitemie
{"title":"Assessing the role of LNG in global carbon neutrality efforts: A project management review","authors":"Ifeanyi Onyedika Ekemezie, Wags Numoipiri Digitemie","doi":"10.30574/gscarr.2024.18.3.0095","DOIUrl":"https://doi.org/10.30574/gscarr.2024.18.3.0095","url":null,"abstract":"This paper review explores the role of LNG in the context of global carbon neutrality efforts. It examines various aspects such as the current state of LNG usage, its environmental impacts, technological advancements, regulatory frameworks, and the challenges and opportunities associated with its integration into the energy mix. Through a comprehensive analysis, this review aims to provide insights into how project management principles can facilitate the effective implementation of LNG projects to support the transition towards a carbon-neutral future. The transition to a carbon-neutral global economy is an imperative challenge of the 21st century, necessitating a profound shift in energy systems and practices. At the forefront of this transition, liquefied natural gas (LNG) has emerged as a potential bridge fuel, offering a pathway towards decarburization. This project management review delves into the multifaceted role of LNG within the context of global carbon neutrality efforts, examining its current usage, environmental implications, technological advancements, regulatory frameworks, and the associated challenges and opportunities. Through a comprehensive analysis, this review aims to shed light on how project management principles can effectively facilitate the implementation of LNG projects to support the transition towards a carbon-neutral future. LNG's emergence as a potential bridge fuel stems from its relatively lower carbon intensity compared to other fossil fuels. As nations strive to reduce greenhouse gas emissions and meet their commitments under the Paris Agreement, LNG presents an opportunity to mitigate climate change while addressing energy security and economic development objectives. However, a nuanced understanding of LNG's role requires a thorough examination of various dimensions. Firstly, the current state of LNG usage underscores its growing significance in the global energy landscape. With LNG trade reaching record highs in recent years, countries are increasingly turning to LNG to meet their energy needs. Major LNG-producing nations such as Qatar, Australia, and the United States have invested in liquefaction infrastructure, enabling the export of LNG to markets around the world. Additionally, LNG is utilized across diverse sectors, including power generation, industrial processes, transportation, and residential heating, highlighting its versatility and applicability. Despite its potential benefits, LNG is not without environmental impacts. The extraction, production, and transportation of natural gas, the primary component of LNG, can result in methane emissions, a potent greenhouse gas. In conclusion, LNG has emerged as a potential bridge fuel in the transition towards a carbon-neutral global economy. Its relatively lower carbon intensity, versatility, and scalability make it a viable option for reducing greenhouse gas emissions while meeting energy demand. However, realizing the full potential of LNG requires care","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"40 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140364268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Performance, privacy, and security issues of TCP/IP at the application layer: A comprehensive survey 应用层 TCP/IP 的性能、隐私和安全问题:全面调查
GSC Advanced Research and Reviews Pub Date : 2024-03-30 DOI: 10.30574/gscarr.2024.18.3.0106
Timothy Murkomen
{"title":"Performance, privacy, and security issues of TCP/IP at the application layer: A comprehensive survey","authors":"Timothy Murkomen","doi":"10.30574/gscarr.2024.18.3.0106","DOIUrl":"https://doi.org/10.30574/gscarr.2024.18.3.0106","url":null,"abstract":"TCP/IP is the backbone of modern network communication, connecting devices across the world. TCP/IP at its core is a suite of protocols that enables the transmission of data between computers, facilitating the foundation of the interconnected global network. At the Application Layer of TCP/IP is where the interaction between software applications and the network occurs. The user-centric protocols such as HTTP, SMTP, FTP, POP3, IMAP and DNS facilitate various tasks at this layer such as web browsing, email communication, and file transfer. This comprehensive survey conducted an exploration of the performance, security and privacy issues at the application layer of the TCP/IP. It initiated by providing a background of TCP/IP model, it’s architecture and the core characteristics, with major focus on the application layer. This paper aimed to discuss the state-of-the-art of performance, privacy and security concerns in TCP/IP application layer. It also proposed future research areas to equip researchers, practitioners, policy makers and the decision makers with tangible knowledge, offering guidance in navigating the performance, privacy and security concerns in TCP/IP Application Layer. It aimed to discuss the current performance, privacy and security research gaps at the Application Layer of the TCP/IP Model. The findings of this research sheds light on the performance, privacy and security issues while suggesting the countermeasures to strengthen and optimize the overall performance, security and privacy of TCP/IP model at the application layer. The paper finally suggests future directions and research areas at the TCP/IP application layer.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"67 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140364943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Facilitators and barriers to the development of giftedness in children 儿童资优发展的促进因素和障碍
GSC Advanced Research and Reviews Pub Date : 2024-03-30 DOI: 10.30574/gscarr.2024.18.3.0085
Pantelis Pergantis
{"title":"Facilitators and barriers to the development of giftedness in children","authors":"Pantelis Pergantis","doi":"10.30574/gscarr.2024.18.3.0085","DOIUrl":"https://doi.org/10.30574/gscarr.2024.18.3.0085","url":null,"abstract":"Giftedness can be interpreted as a multifactorial set of special abilities and skills, that the individual begins to express from an early developmental age. Many believe that the concept of giftedness goes beyond and includes not only IQ but also other factors. The purpose of this literature review is to collect recent data according to factors other than socio/cultural and economic that may influence the expression of giftedness in children. In the introduction giftedness is discussed according to several elements that may intervene in the acceptance of a universal definition and identification of this specific population and the main part explores several factors that may prevent giftedness through inhibition of cognitive and emotional aspects of daily living of children including children with Neurodevelopmental Disorders.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140361748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proximate analysis, total phenolic content, acute toxicity, anti-oxidative and anti-inflammatory studies of Vigna unguiculata and Citrus limon using Wister rat models 利用 Wister 大鼠模型对 Vigna unguiculata 和 Citrus limon 进行近似分析、总酚含量、急性毒性、抗氧化和抗炎研究
GSC Advanced Research and Reviews Pub Date : 2024-03-30 DOI: 10.30574/gscarr.2024.18.3.0111
Daniel Ikechukwu Oraekei, Chukwuka Benjamin Uzodinma, Uchechukwu Harrison Orji, Marcellus Ejike Nnamani, Onyeka Chinwuba Obidiegwu, Nnamdi Markben Adione, Mitchelle Chioma Ezeobi
{"title":"Proximate analysis, total phenolic content, acute toxicity, anti-oxidative and anti-inflammatory studies of Vigna unguiculata and Citrus limon using Wister rat models","authors":"Daniel Ikechukwu Oraekei, Chukwuka Benjamin Uzodinma, Uchechukwu Harrison Orji, Marcellus Ejike Nnamani, Onyeka Chinwuba Obidiegwu, Nnamdi Markben Adione, Mitchelle Chioma Ezeobi","doi":"10.30574/gscarr.2024.18.3.0111","DOIUrl":"https://doi.org/10.30574/gscarr.2024.18.3.0111","url":null,"abstract":"Herbal medicines have been in use for thousands of years. It is estimated that 80% of world population rely on traditional herbal medicine for prophylaxis and therapy of different ailments. In recent years, there has been an upsurge in the use of these herbal remedies due to their cultural acceptability, availability, affordability, efficacy and safety claims. This study carried out the proximate analysis, total phenolic and Citric acid contents, acute toxicity, anti-oxidative and anti-inflammatory studies of Vigna unguiculata and Citrus limon using Wister rat models. Wister rats (135 – 140 g) were used for this study. Vigna unguiculata was extracted using ethanol for 72 hours. Proximate analysis, Citric acid content of Citrus limon, total phenolic content, acute toxicities, anti-oxidative and anti-inflammatory studies were done. The yield of the extract was 1.9%. The LD50 was greater than 5,000 mg/kg body weight. The Citric acid content of Citrus limon was 54.2 + 0.003 mg/ml. The proximate analysis showed the presence of protein, fat, carbohydrate, dietary fibre, moisture, and iron while total phenolic contents of Vigna unguiculata and Citrus limon were 15.3 and 19.3 mgGAE/L respectively. The combination of Vigna unguiculata and Citrus limon exhibited greatest anti-oxidation effect and recorded malondialdehyde concentration of 3.66 ± 0.34 nmol/ml as compared to the individual herbs that recorded 6.14 ± 0.38 and 4.28 ± 0.12 nmol/ml respectively. In anti-inflammatory assay, Vigna unguiculata had the best percentage inhibition of heat induced hemolysis of 62.79%. In conclusion, Vigna unguiculata and Citrus limon had synergistic antioxidant and antagonistic anti-inflammatory activities.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"39 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140362361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nexus between financial development, foreign direct investment, and renewable energy consumption: Evidence from SSA 金融发展、外国直接投资与可再生能源消费之间的联系:撒南非洲的证据
GSC Advanced Research and Reviews Pub Date : 2024-03-30 DOI: 10.30574/gscarr.2024.18.3.0109
Md. Qamruzzaman
{"title":"Nexus between financial development, foreign direct investment, and renewable energy consumption: Evidence from SSA","authors":"Md. Qamruzzaman","doi":"10.30574/gscarr.2024.18.3.0109","DOIUrl":"https://doi.org/10.30574/gscarr.2024.18.3.0109","url":null,"abstract":"This study examines the nexus between urbanization (UR), gross capital formation (GCF), trade openness (TO), and renewable energy consumption (REC) to understand their interplay and implications for renewable energy adoption. Analyzing the data reveals a negative correlation between UR, GCF, TO, and REC, highlighting challenges in promoting renewable energy amidst urbanization, capital formation, and global trade integration. Policy interventions are crucial to address barriers hindering renewable energy uptake. Recommendations include incentivizing foreign direct investment, enhancing technology transfer, incentivizing clean energy investments, and promoting financial literacy. Integrated urban planning and alignment of capital formation policies with renewable energy goals are essential strategies to accelerate renewable energy adoption. This study offers valuable insights for policymakers and stakeholders seeking to promote renewable energy development and sustainability.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140363390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipid-based nanoparticles and their recent advances 脂基纳米颗粒及其最新进展
GSC Advanced Research and Reviews Pub Date : 2024-03-30 DOI: 10.30574/gscarr.2024.18.3.0096
Onteru Sujeevan
{"title":"Lipid-based nanoparticles and their recent advances","authors":"Onteru Sujeevan","doi":"10.30574/gscarr.2024.18.3.0096","DOIUrl":"https://doi.org/10.30574/gscarr.2024.18.3.0096","url":null,"abstract":"Lipid-based nanoparticles hold great potential for drug delivery, providing biocompatibility and the ability to encapsulate both hydrophilic and hydrophobic drugs. However, there are certain challenges associated with small molecules, such as leakage and premature release, which can compromise their effectiveness. Despite these challenges, lipid nanoparticles offer advantages in terms of solubility, stability, and targeted delivery, thereby reducing side effects. Additionally, they can be customized for specific molecules, ensuring biocompatibility and biodegradability. While complications may arise, lipid nanoparticles offer numerous benefits for loading biomolecules, improving pharmacokinetics, and enhancing therapeutic effects. It is important to address stability and loading challenges when encapsulating biomolecules and consider potential immunogenic responses that may impact biocompatibility and safety.","PeriodicalId":12791,"journal":{"name":"GSC Advanced Research and Reviews","volume":"12 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140364604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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