Frontiers in Life Science最新文献

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Cardiac regeneration: 20 years of development and update in zebrafish and mouse 心脏再生:斑马鱼和小鼠 20 年的发展与更新
Frontiers in Life Science Pub Date : 2024-02-07 DOI: 10.1080/26895293.2024.2308904
Lekun Gui, Lijun Jin, Huangjun Liu
{"title":"Cardiac regeneration: 20 years of development and update in zebrafish and mouse","authors":"Lekun Gui, Lijun Jin, Huangjun Liu","doi":"10.1080/26895293.2024.2308904","DOIUrl":"https://doi.org/10.1080/26895293.2024.2308904","url":null,"abstract":"Cardiovascular diseases are one of the leading causes of death globally. The primary pathological mechanism in myocardial infarction and heart failure is irreversible cardiomyocyte loss. The conven...","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"266 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139764289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
16S rRNA gene sequencing of non-lactic acid bacteria cultures from lait caillé in Burkina Faso 布基纳法索麦乳精中非乳酸菌培养物的 16S rRNA 基因测序
Frontiers in Life Science Pub Date : 2024-01-31 DOI: 10.1080/26895293.2024.2309346
Geoffroy Romaric Bayili, Clarisse S. Compaoré, Bréhima Diawara, Lene Jespersen, Hagretou Sawadogo-Lingani
{"title":"16S rRNA gene sequencing of non-lactic acid bacteria cultures from lait caillé in Burkina Faso","authors":"Geoffroy Romaric Bayili, Clarisse S. Compaoré, Bréhima Diawara, Lene Jespersen, Hagretou Sawadogo-Lingani","doi":"10.1080/26895293.2024.2309346","DOIUrl":"https://doi.org/10.1080/26895293.2024.2309346","url":null,"abstract":"Diverse species of lactic acid bacteria (LAB) are involved in the spontaneous fermentation of lait caillé, a traditional milk product from Burkina Faso. However, there is little information on the ...","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139764219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of differentially expressed genes in hypertension and hypertensive cerebral hemorrhage via RNA-sequencing 通过 RNA 序列分析高血压和高血压性脑出血的差异表达基因
Frontiers in Life Science Pub Date : 2024-01-17 DOI: 10.1080/26895293.2024.2304349
Hongwu Qi, Min Qiao, Yansong Liu, Weijun Zeng, Lizhao Zhang, Hongjun Guo
{"title":"Analysis of differentially expressed genes in hypertension and hypertensive cerebral hemorrhage via RNA-sequencing","authors":"Hongwu Qi, Min Qiao, Yansong Liu, Weijun Zeng, Lizhao Zhang, Hongjun Guo","doi":"10.1080/26895293.2024.2304349","DOIUrl":"https://doi.org/10.1080/26895293.2024.2304349","url":null,"abstract":"Hypertension (HT) is a major cause of intracerebral hemorrhage (ICH), and hypertensive cerebral hemorrhage (HCH) has a serious impact on life quality of patients and gives society a heavy burden. T...","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139483687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the yield and yield attributing characters of oat (Avena sativa L.) grown under different tillage methods and NPK fertilizer rates in semi-arid conditions 在半干旱条件下采用不同耕作方法和氮磷钾肥量种植燕麦(Avena sativa L.)的产量和产量特征评估
Frontiers in Life Science Pub Date : 2024-01-16 DOI: 10.1080/26895293.2024.2304338
Marwan Noori Ramadhan
{"title":"Assessment of the yield and yield attributing characters of oat (Avena sativa L.) grown under different tillage methods and NPK fertilizer rates in semi-arid conditions","authors":"Marwan Noori Ramadhan","doi":"10.1080/26895293.2024.2304338","DOIUrl":"https://doi.org/10.1080/26895293.2024.2304338","url":null,"abstract":"Field experiments were conducted to determine the effect of tillage practices and inorganic sources of different combinations of nitrogen, phosphorus, and potassium fertilizers on some physical pro...","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139475577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plac8 regulates the fibrogenic ability of cardiac fibroblasts in mice with myocardial infarction Plac8 可调节心肌梗死小鼠心脏成纤维细胞的成纤维能力
Frontiers in Life Science Pub Date : 2024-01-02 DOI: 10.1080/26895293.2023.2299569
Ting Fu, Jianping Gong, Lei Xu, Ningning Ji
{"title":"Plac8 regulates the fibrogenic ability of cardiac fibroblasts in mice with myocardial infarction","authors":"Ting Fu, Jianping Gong, Lei Xu, Ningning Ji","doi":"10.1080/26895293.2023.2299569","DOIUrl":"https://doi.org/10.1080/26895293.2023.2299569","url":null,"abstract":"Cardiac fibroblasts (CFs) are of vital importance for post-myocardial infarction (MI) remodeling. This study explored the role of Placenta specific 8 (Plac8) in MI on the basis of single-cell RNA-S...","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139096303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The predictive value of admission serum and urine carboxypeptidase-B activation peptide for the severity of acute pancreatitis: a meta-analysis 入院血清和尿液羧基肽酶b激活肽对急性胰腺炎严重程度的预测价值:一项荟萃分析
Frontiers in Life Science Pub Date : 2023-12-01 DOI: 10.1080/26895293.2023.2288534
Liang Dai, Wei-Yan Guo, Xing-Wei Xuan, Xiao-Dong Meng, Yin-Hua Wang, Hai-Xia Chai, Jian-Li Chen, Jun-Mao Chen, Jian-Yi Pu
{"title":"The predictive value of admission serum and urine carboxypeptidase-B activation peptide for the severity of acute pancreatitis: a meta-analysis","authors":"Liang Dai, Wei-Yan Guo, Xing-Wei Xuan, Xiao-Dong Meng, Yin-Hua Wang, Hai-Xia Chai, Jian-Li Chen, Jun-Mao Chen, Jian-Yi Pu","doi":"10.1080/26895293.2023.2288534","DOIUrl":"https://doi.org/10.1080/26895293.2023.2288534","url":null,"abstract":"This meta-analysis examined the predictive value of admission serum and urine carboxypeptidase-B activation peptide (CAPAP) in patients with severe acute pancreatitis. PubMed, Embase, and the Cochr...","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138527181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes in patients with metastatic gastric cancer: a surveillance, epidemiology, and end results program (SEER) database analysis 转移性胃癌患者的预后:一项监测、流行病学和最终结果项目(SEER)数据库分析
Frontiers in Life Science Pub Date : 2023-12-01 DOI: 10.1080/26895293.2023.2288532
Wenhan Li, Yao Tang, Danfang Wang, Jianhui Li
{"title":"Outcomes in patients with metastatic gastric cancer: a surveillance, epidemiology, and end results program (SEER) database analysis","authors":"Wenhan Li, Yao Tang, Danfang Wang, Jianhui Li","doi":"10.1080/26895293.2023.2288532","DOIUrl":"https://doi.org/10.1080/26895293.2023.2288532","url":null,"abstract":"Owing to tumor heterogeneity and individual physiological variations, there remains a necessity to enhance the current prognosis prediction system for metastatic gastric cancer (MGC). This study ai...","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"7 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138527167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phytochemical profile and anti-inflammatory effect of Artemisia annua L. essential oil 黄花蒿挥发油的植物化学特征及抗炎作用
Frontiers in Life Science Pub Date : 2023-12-01 DOI: 10.1080/26895293.2023.2288529
Congcong Zhu, Ge Yan, Manqi Hu, Zongguang Tai, Bin Fan, Pei Zhao, Xiao Miao, Quangang Zhu
{"title":"Phytochemical profile and anti-inflammatory effect of Artemisia annua L. essential oil","authors":"Congcong Zhu, Ge Yan, Manqi Hu, Zongguang Tai, Bin Fan, Pei Zhao, Xiao Miao, Quangang Zhu","doi":"10.1080/26895293.2023.2288529","DOIUrl":"https://doi.org/10.1080/26895293.2023.2288529","url":null,"abstract":"Plant-derived natural compounds are desired for their anti-inflammatory properties. We investigated the chemical composition and the anti-inflammatory effects of the essential oil obtained from lea...","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138527158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Life in Science: Stories, Opinions and Advice for a New Generation of Scientists 科学生活:新一代科学家的故事、观点和建议
Frontiers in Life Science Pub Date : 2023-01-01 DOI: 10.1007/978-3-031-23717-1
{"title":"Life in Science: Stories, Opinions and Advice for a New Generation of Scientists","authors":"","doi":"10.1007/978-3-031-23717-1","DOIUrl":"https://doi.org/10.1007/978-3-031-23717-1","url":null,"abstract":"","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91169879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CRISPR-Cas9-mediated loss-of-function screens CRISPR-Cas9介导的功能丧失筛查
Frontiers in Life Science Pub Date : 2019-01-01 DOI: 10.1080/21553769.2019.1670739
Jia-qing Liu, Tao Li
{"title":"CRISPR-Cas9-mediated loss-of-function screens","authors":"Jia-qing Liu, Tao Li","doi":"10.1080/21553769.2019.1670739","DOIUrl":"https://doi.org/10.1080/21553769.2019.1670739","url":null,"abstract":"The CRISPR-Cas9 system, which uses sgRNA for targeting and the nuclease Cas9 for cleavage, has emerged as a versatile and efficient tool for genome engineering; the system has overcome the limitations of previous technologies and implements various gene editing strategies. The large-scale loss-of-function (LOF) gene scanning technology based on the CRISPR-Cas9 system can be utilized to reveal associations between the genotype and phenotype by inducing efficient and scalable gene perturbations throughout the whole genome. This technology is playing a breakthrough role in the exploration of genes associated with tumors and viruses and its expansion together with RNA sequencing (RNA-seq) can be used to assess multiplexed gene interactions as well as more complicated phenotypes. Here, we introduce LOF genetic screens based on CRISPR knockout (CRISPR ko) and its applications in synthetic lethality and virus-host interactions. We highlight the recent progress on combining this technique with single cell RNA-seq. We also compare the advantages and pitfalls of CRISPR variants, discuss the future perspectives of gene therapy and raise important considerations regarding off-target effects.","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"12 1","pages":"1 - 13"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21553769.2019.1670739","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42039586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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