Alessandro Connor Crocetti, Troy Walker, Fiona Mitchell, Simone Sherriff, Karen Hill, Yin Paradies, Kathryn Backholer, Jennifer Browne
{"title":"Making Big Business Everybody’s Business: Aboriginal leaders’ perspectives on commercial activities influencing aboriginal health in Victoria, Australia","authors":"Alessandro Connor Crocetti, Troy Walker, Fiona Mitchell, Simone Sherriff, Karen Hill, Yin Paradies, Kathryn Backholer, Jennifer Browne","doi":"10.1186/s12992-024-01038-8","DOIUrl":"https://doi.org/10.1186/s12992-024-01038-8","url":null,"abstract":"The commercial determinants of health is a rapidly expanding field of research; however Indigenous perspectives remain notably underrepresented. For Indigenous peoples the intersection of globalisation, colonialism and capitalism may amplify commercially-driven health inequities. This study aimed to explore the perspectives of Aboriginal leaders regarding the influence of commercial activities on Aboriginal health and wellbeing in Victoria, Australia. Semi-structured interviews with 23 Aboriginal leaders from across five sectors (n = 15 urban, n = 8 rural/regional) were analysed through reflexive thematic analysis. Three overarching themes were identified encompassing (i) harmful commercial practices and processes, (ii) improving corporate engagement and (iii) opportunities for self-determination through business. Participants expressed concern over aggressive marketing by the gambling industry, commercial exploitation of Aboriginal culture, the privatisation of public services, and lack of oversignt of corporate social responsibility strategies. Simultaneously, Aboriginal-led businesses were viewed as opportunities for cultural connection, and financial empowerment and self-determination. Numerous commercial entities and activities are perceived to influence Aboriginal health and wellbeing. This study highlights the need for stronger policy and regulation to mitigate harmful industry practices while incentivising the potential positive impacts of the commercial activities on Aboriginal health and wellbeing.","PeriodicalId":12747,"journal":{"name":"Globalization and Health","volume":"40 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140617762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Privatisation of government services in Australia: what is known about health and equity impacts","authors":"Julia Anaf, Toby Freeman, Fran Baum","doi":"10.1186/s12992-024-01036-w","DOIUrl":"https://doi.org/10.1186/s12992-024-01036-w","url":null,"abstract":"Historically in Australia, all levels of government created collective wealth by owning and operating infrastructure, and managing natural assets, key public goods and essential services while being answerable to the public. This strong state tradition was challenged in the 1980s when privatisation became a widespread government approach globally. Privatisation involves displacing the public sector through modes of financing, ownership, management and product or service delivery. The Australian literature shows that negative effects from privatisation are not spread equitably, and the health and equity impacts appear to be under-researched. This narrative overview aims to address a gap in the literature by answering research questions on what evidence exists for positive and negative outcomes of privatisation; how well societal impacts are evaluated, and the implications for health and equity. Database and grey literature were searched by keywords, with inclusion criteria of items limited to Australia, published between 1990 and 2022, relating to any industry or government sector, including an evaluative aspect, or identifying positive or negative aspects from privatisation, contracting out, or outsourcing. Thematic analysis was aided by NVivo qualitative data software and guided by an a-priori coding frame. No items explicitly reflected on the relationship between privatisation and health. Main themes identified were the public cost of privatisation, loss of government control and expertise, lack of accountability and transparency, constraints to accessing social determinants of health, and benefits accruing to the private sector. Our results supported the view that privatisation is more than asset-stripping the public sector. It is a comprehensive strategy for restructuring public services in the interests of capital, with privatisation therefore both a political and commercial determinant of health. There is growing discussion on the need for re-nationalisation of certain public assets, including by the Victorian government. Privatisation of public services is likely to have had an adverse impact on population health and contributed to the increase in inequities. This review suggests that there is little evidence for the benefits of privatisation, with a need for greater attention to political and commercial determinants of health in policy formation and in research.","PeriodicalId":12747,"journal":{"name":"Globalization and Health","volume":"72 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140602732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Characteristics and outcomes of the drug patent linkage system in China","authors":"Xue-Fang Yao","doi":"10.1186/s12992-024-01035-x","DOIUrl":"https://doi.org/10.1186/s12992-024-01035-x","url":null,"abstract":"On July 4, 2021, China officially introduced the drug patent linkage system, which has made more localized adjustments than have similar systems in the US and South Korea. This study describes the characteristics and outcomes of China’s patent linkage system. For this study, we used the database of China’s patent information registration platform for marketed drugs to capture all listed patents and patent certifications from June 25, 2021, to June 30, 2023. We used descriptive statistics for the above data to assess the impact of patent linkage on branded drug manufacturers, generic drug manufacturers, and the public’s access to medicines. During the study period, the patents of 632 branded drugs were listed, and 5058 ANDAs submitted patent certifications to the Registration Platform. Of these 632 branded drugs, 462 (73.1%) drugs were approved before the year of patent registration, and the average number of listed patents per drug was 1.8, with a standard deviation of 1.4. However, of these 5058 ANDAs, P1 certifications accounted for 85.1%, and P3 and P4 certifications accounted for 16% combined. In addition, according to the detailed statistics of P2 certifications, we found that the proportion of patent invalidation cases was 46.4%. The remaining validity of the patents corresponding to P3 certifications was longer, with a median value of 17 months, and the IQR was 10-30.75, ranging from − 2 to 204 months. China’s patent linkage aims to promote the balance of multiple interests —innovation, imitation and public health—and has its own system characteristics. Patent listing and patent certification are the key indicators reflecting the implementation effect of the system. From the perspective of system outcomes, ANDAs have been connected to the patent linkage system in an orderly manner, but the growth of patent challenges is not obvious. Moreover, manufacturers of foreign branded drugs that have not yet entered the Chinese market need to pay more attention to the role of patent listing.","PeriodicalId":12747,"journal":{"name":"Globalization and Health","volume":"51 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140589024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kevin K. C. Hung, Makiko K. MacDermot, Theresa S. I. Hui, Suet Yi Chan, Sonoe Mashino, Catherine P. Y. Mok, Pak Ho Leung, Ryoma Kayano, Jonathan Abrahams, Chi Shing Wong, Emily Y. Y. Chan, Colin A. Graham
{"title":"Correction: Mapping study for health emergency and disaster risk management competencies and curricula: literature review and cross-sectional survey","authors":"Kevin K. C. Hung, Makiko K. MacDermot, Theresa S. I. Hui, Suet Yi Chan, Sonoe Mashino, Catherine P. Y. Mok, Pak Ho Leung, Ryoma Kayano, Jonathan Abrahams, Chi Shing Wong, Emily Y. Y. Chan, Colin A. Graham","doi":"10.1186/s12992-024-01037-9","DOIUrl":"https://doi.org/10.1186/s12992-024-01037-9","url":null,"abstract":"<p><b>Globalization and Health (2024) 20:15</b></p><p>https://doi.org/10.1186/s12992-023-01010-y</p><p>Following publication of the original article, it was brought to the journal's attention that the article had published with the wrong license: it had published with the Creative Commons Attribution 4.0 International License, whereas the correct license is the Creative Commons Attribution 3.0 IGO License. The license has been corrected in the published article. The publisher thanks you for reading this erratum and apologizes for any inconvenience caused.</p><h3>Authors and Affiliations</h3><ol><li><p>Accident and Emergency Medicine Academic Unit, Trauma & Emergency Centre, The Chinese University of Hong Kong, Prince of Wales Hospital, New Territories, Shatin, Hong Kong</p><p>Kevin K. C. Hung, Makiko K. MacDermot, Theresa S. I. Hui, Suet Yi Chan, Catherine P. Y. Mok, Pak Ho Leung, Emily Y. Y. Chan & Colin A. Graham</p></li><li><p>Collaborating Centre for Oxford University, JC School of Public Health and Primary Care, Chinese University of Hong Kong for Disaster and Medical Humanitarian Response (CCOUC), The Chinese University of Hong Kong, Shatin, Hong Kong, China</p><p>Kevin K. C. Hung, Chi Shing Wong, Emily Y. Y. Chan & Colin A. Graham</p></li><li><p>Research Institute of Nursing Care for People and Community, University of Hyogo, 673-8588, Akashi, Japan</p><p>Sonoe Mashino</p></li><li><p>World Health Organization, Centre for Health Development, 651-0073, Kobe, Japan</p><p>Ryoma Kayano</p></li><li><p>Disaster Resilience Initiative, Monash University, Monash University, Clayton, Australia</p><p>Jonathan Abrahams</p></li></ol><span>Authors</span><ol><li><span>Kevin K. C. Hung</span>View author publications<p>You can also search for this author in <span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Makiko K. MacDermot</span>View author publications<p>You can also search for this author in <span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Theresa S. I. Hui</span>View author publications<p>You can also search for this author in <span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Suet Yi Chan</span>View author publications<p>You can also search for this author in <span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Sonoe Mashino</span>View author publications<p>You can also search for this author in <span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Catherine P. Y. Mok</span>View author publications<p>You can also search for this author in <span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Pak Ho Leung</span>View author publications<p>You can also search for this author in <span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Ryoma Kayano</span>View author publications<p>You can also search for this author in <span>PubMed<span> </span>Google Scholar</span></p></li><li><span>Jonathan Abrahams</span>View author publications<p>You can also sear","PeriodicalId":12747,"journal":{"name":"Globalization and Health","volume":"96 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140589026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martha Carnalla, Nancy López-Olmedo, Yenisei Ramírez-Toscano, Luz Mery Cárdenas-Cárdenas, Francisco Canto-Osorio, Herney Rengifo-Reina, David Barrera-Núñez, Josúe Alai Quiroz-Reyes, M. Arantxa Colchero, Tonatiuh Barrientos-Gutiérrez
{"title":"Binge drinking associated with mean temperature: a cross-sectional study among Mexican adults living in cities","authors":"Martha Carnalla, Nancy López-Olmedo, Yenisei Ramírez-Toscano, Luz Mery Cárdenas-Cárdenas, Francisco Canto-Osorio, Herney Rengifo-Reina, David Barrera-Núñez, Josúe Alai Quiroz-Reyes, M. Arantxa Colchero, Tonatiuh Barrientos-Gutiérrez","doi":"10.1186/s12992-024-01033-z","DOIUrl":"https://doi.org/10.1186/s12992-024-01033-z","url":null,"abstract":"The association between environmental temperature and alcohol consumption has not been widely explored despite the potential that increasing temperatures could promote the consumption of alcoholic beverages and the alcohol-related burden of disease. We aimed to explore the association between temperature and binge drinking in Mexican adults from urban cities, overall, and by alcoholic beverage type. Data on 10,552 adults ≥ 18 years was obtained from the 2016 National Survey on Drug, Alcohol, and Tobacco Consumption. The mean annual temperature at the municipality was obtained from the Mexican National Weather Service using monthly temperatures from 2015 to 2016. We analyzed binge drinking for all alcoholic beverages in the last year and by type of alcohol as beer, liquor, wine, and coolers. Associations between mean temperature over the past year and binge drinking over the past year among current drinkers were estimated using multilevel Poisson models with robust standard errors adjusted for age, sex, education level, marital status, and household socioeconomic status, with a fixed effect by region. We observed a non-significant increase in the prevalence of binge drinking for every difference of 1 °C between municipalities of the same region. By alcohol type, a 1 °C increase in mean annual temperature across municipalities of the same region increased the prevalence of beer binge drinking in the past year by 0.9% (PR = 1.009, 95%CI 1.005, 1.013) among beer consumers and the prevalence of coolers’ binge drinking by 3.0% (PR = 1.030, 95%CI 1.003, 1.057) in coolers consumers. We observed non-significant results for liquor binge drinking (PR = 1.047, 95%CI 0.994, 1.102) and wine binge drinking (PR = 1.047, 95% 0.944, 1.161). People living in municipalities with higher temperatures reported a higher beer binge drinking in Mexican cities. This could account for 196,000 cases of beer binge drinking in 2016. The context of each country needs to be considered when generalizing these findings, and they need to be further explored with longitudinal data as there might be implications for climate change. If our findings are confirmed given the forecasted rising temperatures, we could expect an increase in binge drinking and therefore, in the alcohol burden of disease.","PeriodicalId":12747,"journal":{"name":"Globalization and Health","volume":"197 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140588849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A monetary model of global peace and health","authors":"Iman Bastanifar","doi":"10.1186/s12992-024-01029-9","DOIUrl":"https://doi.org/10.1186/s12992-024-01029-9","url":null,"abstract":"This study aims to expand on the concept of peace and health by drawing from Keynes' theory of the economic consequences of peace, in light of the global pandemic experienced in 2020 due to COVID_19. In this paper, I will elaborate on the concept of ‘security’, as an indicator of peace in the time of biological shocks, in order to expand the definition of Keynesian precautionary motivation. This puts forth a new monetary policy model developed to make contributions to achieving global peace. In so doing, I will calculate the optimal growth rate of discount rate through utilizing the Global Peace Index (GPI), adjusted by the Case Fatality Risk (CFR) of COVID-19 in a dynamic shopping time monetary model. This analysis is comprised of the top 15 GDP countries as well as the 10 most and least peaceful countries in 2020. The results indicate that households in more peaceful and healthy countries tend to hold less money compared to those in less peaceful and healthy countries. Besides, the discount rate needs to be reduced due to the outbreak of COVID-19 and the decrease in the level of peace in the economy. Insofar as the imposition of fines through international legal circles on countries with an insignificant health and peace policy will increase the cost of liquidity, other alternative methods of financing will be affor dable for the countries.","PeriodicalId":12747,"journal":{"name":"Globalization and Health","volume":"2016 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140589023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicholas Ngepah, Ariane Ephemia Ndzignat Mouteyica
{"title":"Trends in household out-of-pocket health expenditures and their underlying determinants: explaining variations within African regional economic communities from countries panel data.","authors":"Nicholas Ngepah, Ariane Ephemia Ndzignat Mouteyica","doi":"10.1186/s12992-024-01032-0","DOIUrl":"10.1186/s12992-024-01032-0","url":null,"abstract":"<p><strong>Background: </strong>The persistently high out-of-pocket health spending (OOPHE) in Africa raise significant concern about the prospect of reaching SDG health targets and UHC. The study examines the convergence hypothesis of OOPHE in 40 African countries from 2000 to 2019.</p><p><strong>Methods: </strong>We exploit the <math> <mrow><mrow><mtext>log</mtext> <mspace></mspace></mrow> <mi>t</mi></mrow> </math> , club clustering, and merging methods on a panel of dataset obtained from the World Development Indicators, the World Governance Indicators, and the World Health Organization. Then, we employ the multilevel linear mixed effect model to examine whether countries' macro-level characteristics affect the disparities in OOPHE in the African regional economic communities (RECs).</p><p><strong>Results: </strong>The results show evidence of full panel divergence, indicating persistent disparities in OOPHE over time. However, we found three convergence clubs and a divergent group for the OOPHE per capita and as a share of the total health expenditure. The results also show that convergence does not only occur among countries affiliated with the same regional economic grouping, suggesting disparities within the regional groupings. The findings reveal that countries' improved access to sanitation and quality of governance, increased childhood DPT immunization coverage, increased share of the elderly population, life expectancy at birth, external health expenditure per capita, and ICT (information and communication technology) significantly affect within-regional groupings' disparities in OOPHE per capita. The results also show that an increasing countries' share of elderly and younger populations, access to basic sanitation, ICT, trade GDP per capita, life expectancy at birth, childhood DPT immunization coverage, and antiretroviral therapy coverage have significant impacts on the share of OOPHE to total health expenditure within the regional groupings.</p><p><strong>Conclusion: </strong>Therefore, there is a need to develop policies that vary across the convergence clubs. These countries should increase their health services coverage, adopt planned urbanization, and coordinate trade and ICT access policies. Policymakers should consider hidden costs associated with access to childhood immunization services that may lead to catastrophic health spending.</p>","PeriodicalId":12747,"journal":{"name":"Globalization and Health","volume":"20 1","pages":"27"},"PeriodicalIF":10.8,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10976714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140305393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adrián Alonso Ruiz, Anna Bezruki, Erika Shinabargar, Kaitlin Large, Marcela Vieira, Iulia Slovenski, Yiqi Liu, Surabhi Agarwal, Anna Becker, Suerie Moon
{"title":"Which roads lead to access? A global landscape of six COVID-19 vaccine innovation models.","authors":"Adrián Alonso Ruiz, Anna Bezruki, Erika Shinabargar, Kaitlin Large, Marcela Vieira, Iulia Slovenski, Yiqi Liu, Surabhi Agarwal, Anna Becker, Suerie Moon","doi":"10.1186/s12992-024-01017-z","DOIUrl":"10.1186/s12992-024-01017-z","url":null,"abstract":"<p><strong>Background: </strong>Unequal and inequitable access to Covid-19 vaccines in low- and middle-income countries (L&MICs) was a major political, ethical and public health failure in the pandemic. However, vaccine developers' practices were not monolithic, but rather, took diverse approaches to supplying different countries, with important implications for global access.</p><p><strong>Results: </strong>Using data on R&D investments, regulatory approvals, manufacturing and purchase agreements, and vaccine deliveries, we identified six distinct innovation models that apply across the 14 COVID-19 vaccines with more international presence from 2020-2022. \"Western Early Arrivers\" Pfizer/BioNTech and Moderna supplied the largest volumes quickly and prioritized high-income countries (HICs) from registration to vaccine delivery. \"Western Latecomers\" Janssen and Novavax supplied intermediate volumes later, also prioritizing HICs but with a greater proportion to L&MICs. \"Major Chinese Developers\" Sinopharm and Sinovac supplied intermediate volumes early, primarily to middle-income countries (MICs). \"Russian Developer\" Gamaleya completed development early but ultimately supplied small volumes, primarily to middle-income countries (MICs). \"Cosmopolitan Developer\" Oxford/AstraZeneca supplied large volumes early to HICs and MICs at the lowest prices. Finally, \"Small MIC Developers\" CanSino, Bharat Biotech, Medigen, Finlay Institute and the Center for Genetic Engineering and Biotechnology (CGEB), exported relatively small volumes to a few MICs. Low-income countries (LICs) were not targeted by any developer, and received far fewer doses, later, than any other income group. Almost all developers received public funding and other forms of support, but we found little evidence that such support was leveraged to expand global access.</p><p><strong>Conclusions: </strong>Each of the six innovation models has different implications for which countries get access to which vaccines, how quickly, and at which prices. Each offers different strengths and weaknesses for achieving equitable access. Our findings also suggest that Western firms had the greatest capacity to develop and deliver vaccines quickly during the pandemic, but such capacity is rapidly becoming more globally distributed with MICs playing a significant role, especially in supplying other MICs. Given the critical role of public support in enabling pandemic vaccine development and supply, governments have both the capacity and responsibility to craft international rules that will make responses to future pandemics more equitable and effective.</p>","PeriodicalId":12747,"journal":{"name":"Globalization and Health","volume":"20 1","pages":"25"},"PeriodicalIF":10.8,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10964709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140293352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Towards mission-driven investment in new antimicrobials? What role for Chinese strategic industrial financing vehicles in responding to the challenge of antimicrobial resistance?","authors":"Lewis Husain, Yajing Hu, Yangmu Huang","doi":"10.1186/s12992-024-01030-2","DOIUrl":"10.1186/s12992-024-01030-2","url":null,"abstract":"<p><strong>Background: </strong>Antimicrobial resistance (AMR) causes high levels of global mortality. There is a global need to develop new antimicrobials to replace those whose efficacy is being eroded, but limited incentive for companies to engage in R&D, and a limited pipeline of new drugs. There is a recognised need for policies in the form of 'push' and 'pull' incentives to support this R&D. This article discusses China, a country with a rapidly emerging pharmaceuticals and biotech (P&B) sector, and a history of using coordinated innovation and industrial policy for strategic and developmental ends. We investigate the extent to which 'government guidance funds' (GGFs), strategic industrial financing vehicles (a 'push' mechanism), support the development of antimicrobials as part of China's 'mission-driven' approach to innovation and industrial policy. GGFs are potentially globally significant, having raised approximately US$ 872 billion to 2020.</p><p><strong>Results: </strong>GGFs have a substantial role in P&B, but almost no role in developing new antimicrobials, despite this being a priority in the country's AMR National Action Plan. There are multiple constraints on GGFs' ability to function as part of a mission-driven approach to innovation at present, linked to their business model and the absence of standard markets for antimicrobials (or other effective 'pull' mechanisms), their unclear 'social' mandate, and limited technical capacity. However, GGFs are highly responsive to changing policy demands and can be used strategically by government in response to changing needs.</p><p><strong>Conclusions: </strong>Despite the very limited role of GGFs in developing new antimicrobials, their responsiveness to policy means they are likely to play a larger role as P&B becomes an increasingly important component of China's innovation and industrial strategy. However, for GGFs to effectively play that role, there is a need for reforms to their governance model, an increase in technical and managerial capacity, and supporting ('pull') incentives, particularly for pharmaceuticals such as antimicrobials for which there is strong social need, but a limited market. Given GGFs' scale and strategic importance, they deserve further research as China's P&B sector becomes increasingly globally important, and as the Chinese government commits to a larger role in global health.</p>","PeriodicalId":12747,"journal":{"name":"Globalization and Health","volume":"20 1","pages":"26"},"PeriodicalIF":10.8,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10967126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140293351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhaohui Su, Dean McDonnell, Ali Cheshmehzangi, Barry L Bentley, Sabina Šegalo, Claudimar Pereira da Veiga, Yu-Tao Xiang
{"title":"Where should \"Humans\" be in \"One Health\"? Lessons from COVID-19 for One Health.","authors":"Zhaohui Su, Dean McDonnell, Ali Cheshmehzangi, Barry L Bentley, Sabina Šegalo, Claudimar Pereira da Veiga, Yu-Tao Xiang","doi":"10.1186/s12992-024-01026-y","DOIUrl":"10.1186/s12992-024-01026-y","url":null,"abstract":"<p><p>The culling of animals that are infected, or suspected to be infected, with COVID-19 has fuelled outcry. What might have contributed to the ongoing debates and discussions about animal rights protection amid global health crises is the lack of a unified understanding and internationally agreed-upon definition of \"One Health\". The term One Health is often utilised to describe the imperative to protect the health of humans, animals, and plants, along with the overarching ecosystem in an increasingly connected and globalized world. However, to date, there is a dearth of research on how to balance public health decisions that could impact all key stakeholders under the umbrella of One Health, particularly in contexts where human suffering has been immense. To shed light on the issue, this paper discusses whether One Health means \"human-centred connected health\" in a largely human-dominated planet, particularly amid crises like COVID-19. The insights of this study could help policymakers make more informed decisions that could effectively and efficiently protect human health while balancing the health and well-being of the rest of the inhabitants of our shared planet Earth.</p>","PeriodicalId":12747,"journal":{"name":"Globalization and Health","volume":"20 1","pages":"24"},"PeriodicalIF":5.9,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10964596/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140287364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}