Fukuoka igaku zasshi = Hukuoka acta medica最新文献_第3页

Regulation of Viral Infection and Type 1 Diabetes ; Future Perspective. 病毒感染与1型糖尿病的调节作用未来的视角。

Fukuoka igaku zasshi = Hukuoka acta medica Pub Date : 2016-06-01

Seiho Nagafuchi

引用次数: 0

Living Donor Liver Transplantation in an Elderly Recipient with Preserved Performance Status : A Case Report. 活体肝移植在保留功能状态的老年受者中的应用:1例报告。

Fukuoka igaku zasshi = Hukuoka acta medica Pub Date : 2016-06-01

Tomonari Shimagaki, Tomoharu Yoshizumi, Koichi Kimura, Takashi Motomura, Akihisa Nagatsu, Hirohisa Okabe, Shinji Itoh, Noboru Harada, Norifumi Harimoto, Toru Ikegami, Hideaki Uchiyama, Yuji Soejima, Yoshihiko Maehara

引用次数: 0

Neuraminidase Amino Acid Sequences of Influenza A/H3N2 and B Viruses Isolated from Influenza Patients in the 2014/15 Japanese Influenza Season. 2014/ 2015日本流感季节流感患者分离的A/H3N2和B型流感病毒神经氨酸酶氨基酸序列

Fukuoka igaku zasshi = Hukuoka acta medica Pub Date : 2016-05-01

Hideyuki Ikematsu, Yong Chong, Kenjiro Shirane, Hidehiro Toh, Hiroyuki Sasaki, Shinya Matsumoto, Nozomi Noda, Taeko Hotta, Takeshi Uchiumi, Dongchon Kang

{"title":"Neuraminidase Amino Acid Sequences of Influenza A/H3N2 and B Viruses Isolated from Influenza Patients in the 2014/15 Japanese Influenza Season.","authors":"Hideyuki Ikematsu, Yong Chong, Kenjiro Shirane, Hidehiro Toh, Hiroyuki Sasaki, Shinya Matsumoto, Nozomi Noda, Taeko Hotta, Takeshi Uchiumi, Dongchon Kang","doi":"","DOIUrl":"","url":null,"abstract":"Background: Neuraminidase (NA) is a surface protein essential for influenza virus replication. NA inhibitors are commonly used for the treatment of influenza patients in Japan. Several mutations that reduce the effect of NA inhibitors have been reported. We sequenced the whole NA segment of isolated virus from influenza patients and investigated the relation between the NA amino acid sequence and the 50％ inhibitory concentration (IC_50) of four NA inhibitors.Materials and methods: Forty A/H3N2 and 19 B influenza virus isolated from patients in the 2014/15 influenza season were analyzed. The IC_50 was determined by a neuraminidase inhibition assay using a fluorescent substrate. Viral RNA was amplified by RT-PCR and the genome was sequenced using a next generation sequencer. The deduced amino acid sequences were analyzed.Results: There was no AA change in the NA catalytic site of the A/H3N2 and B viruses isolated in the 2014-15 influenza season. There was no significant relation between the NA amino acids and the IC_50 of the four NA inhibitors for A/H3N2 or B viruses.Conclusion: The catalytic site of NA was highly conserved for these A/H3N2 and B viruses. No emergence of NA amino acid mutations related to the sensitivity of the four currently used NA inhibitors was observed.","PeriodicalId":12665,"journal":{"name":"Fukuoka igaku zasshi = Hukuoka acta medica","volume":"107 5","pages":"98-104"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35228192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Secular Trends and Current Challenges of Lifestyle Diseases : The Hisayama Study. 生活方式疾病的长期趋势和当前挑战:Hisayama研究。

Fukuoka igaku zasshi = Hukuoka acta medica Pub Date : 2016-05-01

Yutaka Kiyohara

引用次数: 0

Endoscopic Submucosal Dissection is Feasible for Very Elderly Patients with Early Gastric Cancer : Comparison of Short-Term and Long-Term Outcomes in Very Elderly and Non-Elderly Patients. 内镜下粘膜剥离术在高龄早期胃癌患者中是否可行:高龄与非高龄患者近期与长期预后的比较

Fukuoka igaku zasshi = Hukuoka acta medica Pub Date : 2016-04-25 DOI: 10.15017/1669232

K. Komori, Kazuhiko Nakamura, E. Ihara, Tsutomu Iwasa, M. Hirahashi, Y. Oda, R. Takayanagi

{"title":"Endoscopic Submucosal Dissection is Feasible for Very Elderly Patients with Early Gastric Cancer : Comparison of Short-Term and Long-Term Outcomes in Very Elderly and Non-Elderly Patients.","authors":"K. Komori, Kazuhiko Nakamura, E. Ihara, Tsutomu Iwasa, M. Hirahashi, Y. Oda, R. Takayanagi","doi":"10.15017/1669232","DOIUrl":"https://doi.org/10.15017/1669232","url":null,"abstract":"Background/Aims\u0000Endoscopic submucosal dissection (ESD) has become a standard procedure for the resection of early gastric cancer (EGC). However, the feasibility of ESD for very elderly patients, aged ≥ 80 years, has not been determined.\u0000\u0000\u0000Methodology\u0000The study population included 67 non-elderly (NE) patients aged ≤ 65 years (80 lesions) and 22 very elderly (VE) patients ≥ 80 years (26 lesions) with EGC who underwent ESD and met the criteria for absolute or expanded indications. Eighteen patients (18 lesions) who underwent ESD but did not meet the criteria for absolute and expanded indications were defined as the outside the indications (OI) group.\u0000\u0000\u0000Results\u0000En bloc and complete resection rates were excellent in both the VE and NE groups, without differing significantly. Although the rates of ischemic heart disease and antithrombotic agent use were higher in the VE than in the NE group, procedure-related complication rates did not differ significantly. Of the seven very elderly patients in the OI group, two underwent additional gastrectomy, and the other five were followed-up without surgery. No patient in any group experienced local recurrence, metastasis or disease-specific death.\u0000\u0000\u0000Conclusions\u0000Short- and long-term outcomes of ESD for VE patients with EGC were favorable and did not differ significantly from outcomes in NE patients. ESD may therefore be a good therapeutic option for both VE and NE patients with EGC.","PeriodicalId":12665,"journal":{"name":"Fukuoka igaku zasshi = Hukuoka acta medica","volume":"28 1","pages":"72-81"},"PeriodicalIF":0.0,"publicationDate":"2016-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78343509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Current Status and Future Perspective of Tolerance Induction in Patients with Kidney Transplantation. 肾移植患者耐受诱导的现状及未来展望

Fukuoka igaku zasshi = Hukuoka acta medica Pub Date : 2016-04-01

Masatoshi Eto, Ario Takeuchi

引用次数: 0

Endoscopic Submucosal Dissection is Feasible for Very Elderly Patients with Early Gastric Cancer : Comparison of Short-Term and Long-Term Outcomes in Very Elderly and Non-Elderly Patients. 内镜下粘膜剥离术在高龄早期胃癌患者中是否可行:高龄与非高龄患者近期与长期预后的比较

Fukuoka igaku zasshi = Hukuoka acta medica Pub Date : 2016-04-01

Keishi Komori, Kazuhiko Nakamura, Eikichiet Ihara, Tsutomu Iwasa, Minako Hirahashi, Yoshinao Oda, Ryoichi Takayanagi

{"title":"Endoscopic Submucosal Dissection is Feasible for Very Elderly Patients with Early Gastric Cancer : Comparison of Short-Term and Long-Term Outcomes in Very Elderly and Non-Elderly Patients.","authors":"Keishi Komori, Kazuhiko Nakamura, Eikichiet Ihara, Tsutomu Iwasa, Minako Hirahashi, Yoshinao Oda, Ryoichi Takayanagi","doi":"","DOIUrl":"","url":null,"abstract":"Background/aims: Endoscopic submucosal dissection (ESD) has become a standard procedure for the resection of early gastric cancer (EGC). However, the feasibility of ESD for very elderly patients, aged ≥ 80 years, has not been determined.Methodology: The study population included 67 non-elderly (NE) patients aged ≤ 65 years (80 lesions) and 22 very elderly (VE) patients ≥ 80 years (26 lesions) with EGC who underwent ESD and met the criteria for absolute or expanded indications. Eighteen patients (18 lesions) who underwent ESD but did not meet the criteria for absolute and expanded indications were defined as the outside the indications (OI) group.Results: En bloc and complete resection rates were excellent in both the VE and NE groups, without differing significantly. Although the rates of ischemic heart disease and antithrombotic agent use were higher in the VE than in the NE group, procedure-related complication rates did not differ significantly. Of the seven very elderly patients in the OI group, two underwent additional gastrectomy, and the other five were followed-up without surgery. No patient in any group experienced local recurrence, metastasis or disease-specific death.Conclusions: Short- and long-term outcomes of ESD for VE patients with EGC were favorable and did not differ significantly from outcomes in NE patients. ESD may therefore be a good therapeutic option for both VE and NE patients with EGC.","PeriodicalId":12665,"journal":{"name":"Fukuoka igaku zasshi = Hukuoka acta medica","volume":"107 4","pages":"72-81"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35228201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coexistence of Reticulate Acropigmentation of Kitamura and Dowling-Degos Disease. 北村网状色素沉着与道林-德戈斯病共存。

Fukuoka igaku zasshi = Hukuoka acta medica Pub Date : 2016-04-01 DOI: 10.15017/1669233

N. Take, M. Kido-Nakahara, M. Furue

引用次数: 1

Coexistence of Reticulate Acropigmentation of Kitamura and Dowling-Degos Disease. 北村网状色素沉着与道林-德戈斯病共存。

Fukuoka igaku zasshi = Hukuoka acta medica Pub Date : 2016-04-01

Nobutoshi Take, Makiko Kido-Nakahara, Masutaka Furue

引用次数: 0

An Invitation to a Spiritual HomeHow Does Postpartum Depression Appear in the Eyes of Onlookers ? 产后抑郁症如何出现在旁观者的眼中?

Fukuoka igaku zasshi = Hukuoka acta medica Pub Date : 2016-03-25 DOI: 10.15017/1661292

H. Nakano

引用次数: 0