{"title":"Anatomical studies at Universidad Central de Venezuela during 1763-1963","authors":"Rafael Romero-Reverón","doi":"10.47307/gmc.2023.131.3.26","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.26","url":null,"abstract":"In Venezuela, Medical studies began in 1763 at Real and Pontifical University of Caracas, conducted by Lorenzo Campins y Ballester. Afterward, José María Vargas, as the first rector of the successive University of Caracas, 1827 reformed the studies of Medicine, Surgery, and Anatomy. He gave lectures and performed anatomical dissections for 25 years. Vargas wrote Curso de Lecciones y demostraciones Anatómicas in 1838. Even under precarious conditions for medical education, a saga of anatomists managed to persist in anatomical studies in Venezuela. In the 20th century, a progressive development in anatomical studies began, led by Luis Razetti and extended by José Izquierdo. Subsequently, these improvements were promoted and developed in both medical schools of the Central University of Venezuela by Jesús Yerena, founder of the Anatomical Museum, and by Francisco Montbrun, founder of “José María Vargas” Medical School and its chair of human anatomy.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135308657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Estandarización de la técnica PCR anidada para la detección de las translocaciones PML/RARα, RUNX1/RUNX1T1 y BCR/ABL en pacientes con leucemia mieloide aguda remitidos a la Unidad de Diagnóstico Molecular de la Fundación Jacinto Convit","authors":"Thais Rivodó","doi":"10.47307/gmc.2023.131.3.9","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.9","url":null,"abstract":"La detección de alteraciones genéticas en pacientes con leucemia mieloide aguda (LMA) permite un mejor pronóstico de la enfermedad y de la respuesta clínica de los pacientes. A través de la técnica de reacción en cadena de la polimerasa con transcripción reversa (RT-PCR, por sus siglas en inglés) anidada, es posible detectar hasta 1 célula mutada/10-6 células sanas, de las translocaciones cromosómicas más frecuentes en pacientes con LMA: t(15;17), t(8;21) y t(9;22). La sensibilidad y eficacia de esta técnica depende fundamentalmente del diseño de los cebadores utilizados en la reacción.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135308668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Estudio piloto de la prevalencia del consumo de cigarrillos en adultos jóvenes en Maracaibo, Venezuela","authors":"Carlos Silva Paredes","doi":"10.47307/gmc.2023.131.3.11","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.11","url":null,"abstract":"Introducción: El tabaquismo se asocia con el desarrollo de enfermedades pulmonares crónicas, enfermedades cardiovasculares y distintos tipos de canceres. Los cigarrillos electrónicos son productos que se han considerados como una alternativa segura a los cigarrillos convencionales y, promocionados como menos dañinos. Estos dispositivos se han asociado a enfermedades pulmonares graves llamado EVALI. Objetivo: determinar la prevalencia del consumo de cigarrillos electrónicos y convencionales en la población de adultos jóvenes. Materiales y métodos: Se realizó un estudio piloto de tipo no experimental, transversal y descriptivo en 225 individuos seleccionados mediante un muestreo no probabilístico, de ambos sexos con edades comprendidas entre los 17 y 25 años de la ciudad de Maracaibo, Venezuela.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135308672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endoscopic dacryocystorhinostomy as treatment for lacrimal pathway obstructions: Serial case reports","authors":"Muhammad Fadjar Perkasa","doi":"10.47307/gmc.2023.131.3.23","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.23","url":null,"abstract":"Introduction: The lacrimal system is an important system for maintaining the normal condition of the ocular surface. Obstruction of the lacrimal duct can lead to inflammation and accumulation of debris and pathogens such as bacteria or fungi in the lacrimal sac and then cause dacryocystitis. This disease is often found in children or adults over 40 years of age, especially women with a peak incidence at the age of 60 to 70 years. Complaints usually include eye discomfort and redness accompanied by excessive tears. The diagnosis can be made based on physical examination, staining tests, and imaging photographs, such as dacryocystography, computed tomography (CT), and magnetic resonance imaging (MRI). Management of dacryocystitis is conservative, supportive, and surgical with an open or endonasal approach.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135308658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Urogenital disease morbidity among the adult and child population of the Osh Region for the period from 2010 to 2019","authors":"Isabek Tazhidinovich Gulamov","doi":"10.47307/gmc.2023.131.3.17","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.17","url":null,"abstract":"It is presented the results of a study on the prevalence, structure, and trends in urogenital diseases in the adult population of the Osh Region of Kyrgyzstan for the period between 2010 and 2019. Official statistics on morbidity provided by the National Statistical Committee of the Kyrgyz Republic are used as materials for the study. Information on the main indices characterizing adult morbidity is selected and summarized, and dynamic statistical analysis of the data is performed. The data analysis demonstrates that the highest morbidity of urogenital diseases in the Osh Region was registered in 2017, and the lowest – in 2019.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135308670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COVID-19: Hematological and laboratory parameters in patients hospitalized during the second and third epidemic wave (2021-2022) at a private hospital in Caracas, Venezuela","authors":"Aixa Müller","doi":"10.47307/gmc.2023.131.3.15","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.15","url":null,"abstract":"The first wave of COVID-19 in Venezuela began in March 2020 and had a maximum of cases in August 2020. New outbreaks occurred in 2021 and 2022, during which we studied 603 hospitalized cases at the Clinica El Avila de Caracas: 370 (61.35 %) male and 233 (38.14 %) female. The average age was 65 years (range: 18-99 years). The hematological and laboratory studies were similar to those reported in 2020other studies outside of Venezuela. One hundred two (102) patients were transferred to the Intensive Care Unit (ICU). 80 % of these patients had not been vaccinated or did not receive the full vaccination schedule against COVID-19. The overall mortality of the 603 patients was 11.27 %.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"199 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135308651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Conceptos actuales del diagnóstico y tratamiento de la artritis psoriásica","authors":"Juan Camilo Santacruz","doi":"10.47307/gmc.2023.131.3.19","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.19","url":null,"abstract":"La artritis psoriásica (APs) es una enfermedad autoinmune sistémica asociada a la psoriasis, conocida ahora dentro de un único espectro llamado enfermedad psoriásica, y otras comorbilidades como lo son enfermedad cardiovascular, síndrome metabólico, inflamación intestinal subclínica, trastornos del estado de ánimo, mayor riesgo de infecciones crónicas y fibromialgia. El compromiso articular en esta enfermedad es de presentación heterogénea, incluyendo tanto las articulaciones periféricas como axiales, acompañadas de otras manifestaciones clínicas como lo son la presencia de entesitis, dactilitis y el compromiso ungueal. Gracias a los avances en el entendimiento de su fisiopatología se ha logrado desarrollar en los últimos años un arsenal terapéutico suficiente para controlar la mayoría de sus dominios clínicos.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135308660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efectos de la inyección subdérmica de pentoxifilina en la integración de los injertos cutáneos de espesor total en un modelo animal","authors":"Linda Rincón-Rubio","doi":"10.47307/gmc.2023.131.3.6","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.6","url":null,"abstract":"Los injertos cutáneos son una herramienta ampliamente utilizada en el campo de la cirugía plástica y reconstructiva, por lo que es de gran importancia la búsqueda de técnicas que permitan una optimización de la integración de los mismos. Este estudio evaluó los efectos macro y microscópicos de la administración subdérmica de pentoxifilina (PTX) en la integración de los injertos cutáneos de espesor total. En un modelo experimental, controlado, aleatorizado, en 8 ratas, distribuidas en 2 grupos, 2 para control y 6 del ensayo experimental.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135307174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical features of patients with cancer of thoracic esophagus and results of their surgical treatment","authors":"Fariz Jamalov","doi":"10.47307/gmc.2023.131.3.7","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.7","url":null,"abstract":"Esophageal cancer takes one of the first places in the structure of morbidity and mortality among malignant diseases. The development of anesthesiology and thoracic resuscitation provided the evolution of the surgical method. Resections of the esophagus with locally-disseminated and complicated forms of cancer have become possible. But even today, the long-term results of surgical treatment don’t satisfy clinicians. Often this is due to the dissemination of the tumor process in most patients at the time of treatment. For this purpose, an analysis of clinical material was carried out, including 89 patients with cancer of thoracic part of esophagus, who underwent reconstructive surgeries (extirpation of the thoracic part of esophagus with simultaneous retromediastinal plasty by stomach tube) in the surgical unit of Republican Clinical Hospital (RCH), n.a. academic M.A.Mir-Gasimov, Baku city. Interventions on the esophagus were performed either of two approaches – upper median laparotomy and left-sided cervicotomy (76 patients – 85,4%) or from three-with the addition of a right sided lateral thoracotomy in the fifth intercostal space (13 patients – 14,6%). There were no deaths due to surgical complications. The fundamental possibility and reasonableness of performing expanded radical interventions has been detected, taking into account the technical resectability of the tumor, which is especially important in working with a group of patients with “late” esophageal cancer criteria, such as the age of the patient, the size of the primary tumors, its local dissemination are not a contraindication to radical surgery.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135307171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Eficacia de la citología, colposcopia y microcolpohisteroscopia en el diagnóstico de lesiones intraepiteliales de cuello uterino","authors":"Claudia Leal Diaz","doi":"10.47307/gmc.2023.131.3.8","DOIUrl":"https://doi.org/10.47307/gmc.2023.131.3.8","url":null,"abstract":"Introducción: La identificación temprana de lesiones preinvasoras de cuello uterino es fundamental y se realiza a través de procedimientos no invasivos. Objetivo: Evaluar la eficacia de la citología, colposcopia y microcolpohisteroscopia en el diagnóstico de lesiones intraepiteliales de cuello uterino. Método: Se realizó una investigación de carácter descriptivo observacional y transversal. Con población de 185 pacientes, mediante la elección de criterios de inclusión y de exclusión, se realizó selección intencional de la muestra que estuvo representada por 17 pacientes, los procedimientos se realizaron en cuatro fases en orden de citología, colposcopia, microcolpohisteroscopia para observar las características de las células en vivo y biopsia.","PeriodicalId":12577,"journal":{"name":"Gaceta Médica de Caracas","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135308652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}