The International Journal of Gastroenterology and Hepatology Diseases最新文献_第2页

Conglomeration of symptomatic Crohn’s Disease and Celiac sprue: a case report from western India and review of the literature 症状性克罗恩病和乳糜泻的聚集:印度西部一例报告和文献回顾

The International Journal of Gastroenterology and Hepatology Diseases Pub Date : 2022-12-30 DOI: 10.2174/2666290602666221230142559

Urvashi Vijay, Shankar Lal Jat, Pratibha Maan, A. Agarwal, A. Mathur, Prashanth N Suravajhala, Bhumandeep kaur

{"title":"Conglomeration of symptomatic Crohn’s Disease and Celiac sprue: a case report from western India and review of the literature","authors":"Urvashi Vijay, Shankar Lal Jat, Pratibha Maan, A. Agarwal, A. Mathur, Prashanth N Suravajhala, Bhumandeep kaur","doi":"10.2174/2666290602666221230142559","DOIUrl":"https://doi.org/10.2174/2666290602666221230142559","url":null,"abstract":"\u0000\u0000Background: Celiac diseases are found to be associated with other autoimmune diseases such as autoimmune thyroiditis, type I diabetes, Addison’s disease, primary biliary cirrhosis, and inflammatory bowel disease (IBD). In literature, only a few cases were described simultaneously presenting both conditions in the same patient.\u0000\u0000\u0000\u0000A 23-year-old Indian male presented with a one-month history of loose motion 10-12 times per day, having watery stool, and nocturnal diarrhea. The patient had pallor, weakness, fatigability, and anorexia/weight loss. The patient also had a history of periumbilical pain abdomen and black-colored stools. In our study, both conditions are clinically symptomatic in the same patient, as proved by endoscopic changes and histopathologically. Esophagogastroduodenoscopy (EGD) examination shows severe scalloping of duodenal folds and nodularity, indicating celiac disease changes. A colonoscopy examination was performed, which revealed multiple linear longitudinal ulcerations, friability, erosions and absent vascularity, which indicates Crohn’s disease. Duodenal biopsy shows celiac disease (Marsh IIIa), and Colonic biopsy shows Crohn’s disease. The patient was treated with improvement in abdominal pain, weight, and anemia.\u0000\u0000\u0000\u0000Celiac and Crohn’s both conditions are clinically symptomatic in the same patient, as proved by endoscopic and histopathological changes.\u0000","PeriodicalId":125135,"journal":{"name":"The International Journal of Gastroenterology and Hepatology Diseases","volume":"534 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123099930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Skin rash after camrelizumab and sorafenib in a patient with advanced hepatocellular carcinoma 一名晚期肝细胞癌患者使用康瑞珠单抗和索拉非尼治疗后出现皮疹

The International Journal of Gastroenterology and Hepatology Diseases Pub Date : 2022-12-14 DOI: 10.2174/2666290602666221214145901

X. Qi, Yuwei Liu, Dongyang Wang

引用次数: 0

Esophageal Angiodysplasia: A Strange Place for One of those 食管血管发育不全:这是其中一个奇怪的地方

The International Journal of Gastroenterology and Hepatology Diseases Pub Date : 2022-12-08 DOI: 10.2174/2666290602666221208094215

Nadeen Y. Sarsour, A. Adejumo, S. Malik

{"title":"Esophageal Angiodysplasia: A Strange Place for One of those","authors":"Nadeen Y. Sarsour, A. Adejumo, S. Malik","doi":"10.2174/2666290602666221208094215","DOIUrl":"https://doi.org/10.2174/2666290602666221208094215","url":null,"abstract":"\u0000\u0000Angiodysplasia, also known as angioectasia, is the most common vascular malformation of the gastrointestinal tract, most often found in patients above the age of sixty. Patients with cirrhosis are at increased risk of bleeding and re-bleeding of these lesions. Angiodysplasias can be found throughout the gastrointestinal (GI) tract and are uncommonly found in the esophagus. The recommended treatment for these lesions is Argon Plasma Coagulation (APC); however, there are numerous mechanical and medical strategies that can also be used to treat angiodysplasia.\u0000\u0000\u0000\u0000This is a case of a 65-year-old woman with decompensated alcoholic cirrhosis and a history of recurrent GI bleeding complicated by hemorrhagic shock presented for anemia. Esophagogastroduodenoscopy (EGD) following her hospitalization was remarkable for bleeding esophageal and gastric angiodysplasias that were successfully treated with APC. The patient returned months later with a recurrent upper GI bleed with EGD, colonoscopy, and video capsule remarkable for angiodysplasias throughout the gastric body, small bowel, and colon without recurrence of the esophageal angiodysplasia.\u0000\u0000\u0000\u0000The purpose of this case is to demonstrate a rare but possible cause of upper GI bleed in patients with decompensated cirrhosis. While angiodysplasia can occur commonly in the stomach, small bowel, and colon, esophageal angioectasia can occur and contribute to a recurrent GI bleed. These should be considered in the differential diagnosis of upper GI bleed and anemia.\u0000","PeriodicalId":125135,"journal":{"name":"The International Journal of Gastroenterology and Hepatology Diseases","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115234659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Drug-induced Liver Injury and Herb-induced Liver Injury Targeting KeyIssues 药物性肝损伤与草药性肝损伤靶向治疗关键问题

The International Journal of Gastroenterology and Hepatology Diseases Pub Date : 2022-09-01 DOI: 10.2174/2666290602666221125161151

R. Teschke

引用次数: 0

Molecular and Serological Testing for Brucellosis in Egypt 埃及布鲁氏菌病的分子和血清学检测

The International Journal of Gastroenterology and Hepatology Diseases Pub Date : 2022-07-21 DOI: 10.2174/2666290601666220721104600

D. Johar, Mahmoud A.M. Abd Elaal, A. Bakr, R. Sakr, E. Bahbah, E. Elshemy, S. Zaky

{"title":"Molecular and Serological Testing for Brucellosis in Egypt","authors":"D. Johar, Mahmoud A.M. Abd Elaal, A. Bakr, R. Sakr, E. Bahbah, E. Elshemy, S. Zaky","doi":"10.2174/2666290601666220721104600","DOIUrl":"https://doi.org/10.2174/2666290601666220721104600","url":null,"abstract":"\u0000\u0000Brucellosis is highly endemic in the Mediterranean Basin, including Egypt. Despite attempts to control the disease in Egypt, there are still significant problems with diagnostic accuracy. The prevalence and incidence of brucellosis are unknown and we have uncertain predictive prognostic tests for brucellosis treatment results. Identification of the actual epidemiological burden of brucellosis in Egypt, and levels of the brucellosis antibody titer among rural and urban populations is critical to the evaluation of combined treatment approaches that achieve lesser relapse rates.\u0000\u0000\u0000\u0000to determine the current prevalence of brucellosis infections in Egypt and changes in its epidemiological pattern.\u0000\u0000\u0000\u0000we compared the available diagnostic yield, sensitivity, specificity, accuracy, cost, and time consumption of serological tests with those from quantitative polymerase chain reaction (qPCR) to establish their ability to meet the diagnostic criteria. Also, we conducted surveillance of the rates of brucellosis infection in both humans and animals.\u0000\u0000\u0000\u0000The enzyme-linked immunosorbent assay (ELISA) and blood cultures were less sensitive diagnostic methods for the detection of brucellosis. These approaches are technically challenging and have a high likelihood of false negatives. Therefore, they are best reserved for suspected cases with negative standard agglutination test (SAT).\u0000\u0000\u0000\u0000A more practical approach to the diagnosis for brucellosis depends on epidemiological testing for risk factors, clinically suspected cases, and SAT titers ≥ 1/320. Strategies to prevent relapsing include: 1) Health education of patients, 2) Long-term triple therapy, e.g., three months, with possible extension to six months in severe or recurrent cases or when complications occur.\u0000","PeriodicalId":125135,"journal":{"name":"The International Journal of Gastroenterology and Hepatology Diseases","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115762423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In Fact, Its an Infarct: New Nodules Seen Status Post TIPS 事实上，这是一种梗塞：TIPS 术后出现的新结节状态

The International Journal of Gastroenterology and Hepatology Diseases Pub Date : 2022-05-09 DOI: 10.2174/2666290601666220509232856

S. Jacob, N. P. Polanco, S. Malik

引用次数: 0

Development of spontaneous intrahepatic portosystemic shunt after endoscopic variceal ligation 内镜下静脉曲张结扎术后出现自发性肝内门体分流术

The International Journal of Gastroenterology and Hepatology Diseases Pub Date : 2022-03-03 DOI: 10.2174/2666290601666220303140639

Shixue Xu, Xiaozhong Guo, Fangfang Yi, X. Qi

引用次数: 0

THE IMPACT OF METABOLIC RISK FACTORS, DIABETES, MEDICATIONS AND COMORBID ILLNESS ON TRANSIT TIME AT CAPSULE ENDOSCOPY: A PROSPECTIVE COHORT STUDY 代谢危险因素、糖尿病、药物和合并症对胶囊内窥镜传输时间的影响:一项前瞻性队列研究

The International Journal of Gastroenterology and Hepatology Diseases Pub Date : 2022-03-03 DOI: 10.2174/2666290601666220303123827

M. Bassan, Robert Cheng, Nak-Jin Choi, Suhirdan Vivekanandarajah, S. Abey, J. Mcdonald

{"title":"THE IMPACT OF METABOLIC RISK FACTORS, DIABETES, MEDICATIONS AND COMORBID ILLNESS ON TRANSIT TIME AT CAPSULE ENDOSCOPY: A PROSPECTIVE COHORT STUDY","authors":"M. Bassan, Robert Cheng, Nak-Jin Choi, Suhirdan Vivekanandarajah, S. Abey, J. Mcdonald","doi":"10.2174/2666290601666220303123827","DOIUrl":"https://doi.org/10.2174/2666290601666220303123827","url":null,"abstract":"\u0000\u0000Video capsule endoscopy (VCE) is a safe and effective way of investigating obscure gastrointestinal bleeding. One of the main limitations of VCE is suboptimal visualisation due to prolonged gastric transit time (GTT) or rapid small intestinal transit time (SITT). The role of metabolic risk factors, diabetes, and medications on transit times remains unclear.\u0000\u0000\u0000\u0000The aim of this study was to assess the impact of diabetes, obesity, medications, and metabolic syndrome on transit times at VCE.\u0000\u0000\u0000\u0000The study performed was a single centre, observational study.\u0000\u0000\u0000\u0000Significant predictors of decreased GTT were increasing age and use of beta blocker medication. No predictive factors for increased GTT were identified. Significant predictors of decreased SITT on univariate analysis were increasing GTT, serum glucose >5mmol/L, obesity, and diabetes. On multivariate analysis increasing GTT and increased glucose remained significant.\u0000\u0000\u0000\u0000Beta-blocker therapy reduces GTT. Hyperglycaemia at the time of VCE reduces SITT. These allow for possible therapeutic strategies to improve the diagnostic yield at VCE.\u0000","PeriodicalId":125135,"journal":{"name":"The International Journal of Gastroenterology and Hepatology Diseases","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124708855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Risk of Opportunistic Infections in Patients with Inflammatory Bowel Disease 炎症性肠病患者机会性感染的风险

The International Journal of Gastroenterology and Hepatology Diseases Pub Date : 2022-01-24 DOI: 10.2174/2666290601666220124111511

Maede Ghanaeipour, Nima Behnaminia, E. Khadem, Amir Hossein Nafari

{"title":"The Risk of Opportunistic Infections in Patients with Inflammatory Bowel Disease","authors":"Maede Ghanaeipour, Nima Behnaminia, E. Khadem, Amir Hossein Nafari","doi":"10.2174/2666290601666220124111511","DOIUrl":"https://doi.org/10.2174/2666290601666220124111511","url":null,"abstract":"\u0000\u0000Immunity-related issues are the main concerns of patients undergoing inflammatory bowel disease (IBD) treatment. The treatment of IBD during the last decade has evolved due to the ever-increasing utilization of immunomodulators, which has caused the potential of contracting opportunistic infections to become the main immunity concern for patients affected by IBD.\u0000\u0000\u0000\u0000Studies on opportunistic infections in patients with IBD that were identified in databases such as Google Scholar, PubMed, and Scopus were reviewed and included.\u0000\u0000\u0000\u0000IBD patients are a high-risk population for opportunistic infections, with age being a significant factor. The primary therapy for IBD patients includes the suppression of the immunity system, together with immunodeficiency and biological treatments, which, first of all, must be standardized. Since treatment with suppressive medicine, which is the original method for curing IBD, causes viral infections and the growth of various bacteria, factors suppressing the body's immunity system must be temporarily suspended, or the consumption dosage of sensitive antibiotics should be reduced. Biological treatment and anti-integrin antibodies will lead to the danger of being affected by opportunistic infections in patients with IBD. Still, the threat of these infections is not severe.\u0000\u0000\u0000\u0000The worldwide research society must conduct further research into a therapeutic strategy for IBD patients to reduce susceptibility and the risk of opportunistic infection.There are still unknowns about how these individuals and the medicines they were given reacted to different infections, and more detailed clinical observations are required.\u0000","PeriodicalId":125135,"journal":{"name":"The International Journal of Gastroenterology and Hepatology Diseases","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125821331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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The gut microbiota changes in obese people: a new perspective for the modern medicine 肥胖人群肠道菌群的变化:现代医学的新视角

The International Journal of Gastroenterology and Hepatology Diseases Pub Date : 2021-10-18 DOI: 10.2174/2666290601666211018120831

L. Abenavoli, A. Procopio, E. Scarpellini

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