{"title":"[Coronary computed tomography and intracoronary imaging for the diagnosis of coronary artery disease and the guidance of percutaneous revascularization].","authors":"Alberto Sarti, Andrea Erriquez","doi":"10.1714/4418.44148","DOIUrl":"10.1714/4418.44148","url":null,"abstract":"","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 2","pages":"e2"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The search for details in electrocardiography: the analytical-deductive method of Giuseppe Oreto. Concealed junctional premature beats as the underlying cause of pseudo-atrioventricular block].","authors":"Gaetano Satullo","doi":"10.1714/4418.44137","DOIUrl":"https://doi.org/10.1714/4418.44137","url":null,"abstract":"","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 2","pages":"80-83"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cosimo Carriere, Alberto Guarnaccia, Eva Del Mestre, Michele Lo Casto, Davide Maione, Francesca Piccinin, Massimo Zecchin, Marco Merlo, Gianfranco Sinagra
{"title":"[Remote monitoring in patients with heart failure and ventricular dysfunction: operating protocol of Trieste Cardiology].","authors":"Cosimo Carriere, Alberto Guarnaccia, Eva Del Mestre, Michele Lo Casto, Davide Maione, Francesca Piccinin, Massimo Zecchin, Marco Merlo, Gianfranco Sinagra","doi":"10.1714/4418.44140","DOIUrl":"https://doi.org/10.1714/4418.44140","url":null,"abstract":"<p><p>Chronic heart failure is a condition characterized by an increasing epidemiological impact, ranking among the leading causes of morbidity and mortality, and often requiring complex and costly outpatient and hospital management. Patients with heart failure with reduced left ventricular systolic function who have implantable cardiac defibrillators with or without cardiac resynchronization therapy can now benefit from innovative telemonitoring algorithms designed to predict acute decompensated heart failure and to promote early prevention and treatment strategies. Composite indices generated by devices from Boston Scientific (HeartLogic™), Biotronik (HeartInsight), and Medtronic (TriageHF), through multiparametric scores and specific alert notifications, indicate hemodynamic changes in the subclinical and often asymptomatic phase with high sensitivity and specificity, forewarning of acute destabilizations. This review proposes an organizational model aimed at an integrated and coordinated management of heart failure alerts between the hospital (particularly the Pacemaker and the Heart Failure Clinic of Cardiology in Trieste) and the regional Cardiology network, following uniform diagnostic and therapeutic criteria. By drafting a management protocol, our Cardiology department monitors heart failure patients with reduced systolic function using a flowchart that categorizes patients by risk of acute events, starting from the alert and a simple phone contact. Stable patients are monitored remotely for 2 weeks until the heart failure alert resolves, but if the alert persists, they are referred to the Heart Failure section or regional Cardiology for further management. In-alert patients with two or more objective signs/symptoms of heart failure are provided with educational and behavioral advice and have their current therapy adjusted, with remote follow-up every 15 days. If the alert persists for more than 2 weeks after onset, the case is forwarded to the Heart Failure section for a phone reassessment and further investigation, including blood tests and NT-proBNP level measurements.</p>","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 2","pages":"90-99"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Corrigendum of Il cuore che visse tre volte by Maria Frigerio].","authors":"Giuseppe Di Pasquale","doi":"10.1714/4418.44147","DOIUrl":"https://doi.org/10.1714/4418.44147","url":null,"abstract":"","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 2","pages":"146"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raffaele Falco, Matteo Baroni, Lorenzo Gigli, Fabrizio Guarracini, Marco Carbonaro, Giulia Colombo, Sara Vargiu, Antonio Frontera, Marco Paolucci, Marisa Varrenti, Alberto Preda, Patrizio Mazzone
{"title":"[Protection from sudden cardiac death using a new extravascular implantable cardioverter-defibrillator device: a literature review and a case series from a high-volume single center].","authors":"Raffaele Falco, Matteo Baroni, Lorenzo Gigli, Fabrizio Guarracini, Marco Carbonaro, Giulia Colombo, Sara Vargiu, Antonio Frontera, Marco Paolucci, Marisa Varrenti, Alberto Preda, Patrizio Mazzone","doi":"10.1714/4418.44141","DOIUrl":"https://doi.org/10.1714/4418.44141","url":null,"abstract":"<p><p>The extravascular implantable cardioverter-defibrillator (EV-ICD, Aurora, Medtronic, Minneapolis, MN, USA) has recently been validated as a new device for preventing arrhythmic death with the aim of reducing vascular and mechanical complications of transvenous ICDs and overcoming the limitations of subcutaneous ICDs. A dedicated learning program is required and, in addition to the electrophysiologist, the implantation procedure must be performed with the assistance of an anesthesiologist for general anesthesia induction and, especially in the early stages of training, a cardiothoracic surgeon for assistance during access to the retrosternal space where the lead should be placed. The objective of this case series is to describe the experience at our high-volume hospital where we treated the first 10 patients with the Aurora EV-ICD device over a period of 8 months.</p>","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 2","pages":"100-105"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chiara Servoli, Gaia Spaziani, Laura Angeli, Paola Livi, Elena Bennati, Carlo Dani, Federico Mecacci, Silvia Favilli
{"title":"[Twin pregnancy in a young woman with Fontan circulation].","authors":"Chiara Servoli, Gaia Spaziani, Laura Angeli, Paola Livi, Elena Bennati, Carlo Dani, Federico Mecacci, Silvia Favilli","doi":"10.1714/4418.44143","DOIUrl":"https://doi.org/10.1714/4418.44143","url":null,"abstract":"<p><p>We report the case of a young woman with Fontan circulation who successfully completed a twin pregnancy. The key role of a multidisciplinary Pregnancy Heart Team for preconception counseling and pregnancy management is emphasized.</p>","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 2","pages":"120-122"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucia Mazzolai, Gisela Teixido-Tura, Stefano Lanzi, Vinko Boc, Eduardo Bossone, Marianne Brodmann, Alessandra Bura-Rivière, Julie De Backer, Sebastien Deglise, Alessandro Della Corte, Christian Heiss, Marta Kałużna-Oleksy, Donata Kurpas, Carmel M McEniery, Tristan Mirault, Agnes A Pasquet, Alex Pitcher, Hannah A I Schaubroeck, Oliver Schlager, Per Anton Sirnes, Muriel G Sprynger, Eugenio Stabile, Françoise Steinbach, Matthias Thielmann, Roland R J van Kimmenade, Maarit Venermo, Jose F Rodriguez-Palomares
{"title":"[2024 ESC Guidelines for the management of peripheral arterial and aortic diseases].","authors":"Lucia Mazzolai, Gisela Teixido-Tura, Stefano Lanzi, Vinko Boc, Eduardo Bossone, Marianne Brodmann, Alessandra Bura-Rivière, Julie De Backer, Sebastien Deglise, Alessandro Della Corte, Christian Heiss, Marta Kałużna-Oleksy, Donata Kurpas, Carmel M McEniery, Tristan Mirault, Agnes A Pasquet, Alex Pitcher, Hannah A I Schaubroeck, Oliver Schlager, Per Anton Sirnes, Muriel G Sprynger, Eugenio Stabile, Françoise Steinbach, Matthias Thielmann, Roland R J van Kimmenade, Maarit Venermo, Jose F Rodriguez-Palomares","doi":"10.1714/4411.44050","DOIUrl":"https://doi.org/10.1714/4411.44050","url":null,"abstract":"","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 1 Suppl 1","pages":"e1-e169"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143003794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Combination therapy for the treatment of hypercholesterolemia: primary and secondary prevention].","authors":"Stefania Angela Di Fusco, Furio Colivicchi","doi":"10.1714/4425.44226","DOIUrl":"10.1714/4425.44226","url":null,"abstract":"<p><p>The reduction of low-density lipoprotein cholesterol (LDL-C) is the cornerstone of atherosclerotic cardiovascular diseases management, both in primary and secondary prevention. The use of more lipid-lowering agents represents an effective and safe option to reduce LDL-C with the advantage of a better adherence to treatment compared to the use of higher statin dosages as monotherapy. This review focuses on therapeutic targets as recommended in different clinical settings in primary and secondary prevention, and analyzes evidence on the statin/ezetimibe combination use in primary prevention. Furthermore, we discuss the impact of rosuvastain/ezetimibe combination in secondary prevention and report available data on LDL-C reduction and on the effects on atherosclerotic plaques and clinical events.</p>","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 1","pages":"e17-e22"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Combination therapy in arterial hypertension: how to personalize treatment].","authors":"Alessandra Bacca, Stefano Taddei","doi":"10.1714/4425.44227","DOIUrl":"10.1714/4425.44227","url":null,"abstract":"<p><p>Combination therapy is necessary in approximately 70% of hypertensive patients to achieve adequate blood pressure control. Furthermore, fixed combinations have a documented clinical utility as they increase therapeutic adherence. The most effective combinations of antihypertensive drugs are those made with drugs that have a complementary effect on the blood pressure regulation systems. In other words, it is rational to combine drugs that block the renin-angiotensin system or the sympathetic nervous system with drugs that activate these systems. Therefore, with regard to antihypertensive efficacy, both the fixed combination ACE-inhibitor/calcium channel blocker and the fixed combination AT1 antagonist/calcium channel blocker are rational as they have an additive effect on blood pressure reduction and improve the tolerability of the individual molecules. However, the choice of a combination therapy should not be limited only to evaluating the efficacy on blood pressure levels, but a more important target is certainly the ability to reduce cardiovascular events. As regards calcium channel blockers, the molecule with the best evidence of clinical efficacy in randomized controlled studies is certainly amlodipine (VALUE, CAMELOT, PREVENT, CAPARES, ASCOT and ACCOMPLISH studies). Also as regards ACE-inhibitors, the use of ramipril is supported by a significant series of clinical studies (HOPE, micro-HOPE and AIRE). In accordance with their efficacy, both molecules are the most used in daily clinical practice. It is however necessary to underline that, among AT1 antagonists, the best scientific literature certainly supports the efficacy of candesartan (SCOPE, TROPHY, AMAZE, CALM and DIRECT studies) which should therefore be the reference molecule in clinical use. Therefore, the combinations of ramipril/amlodipine and candesartan/amlodipine represent a therapeutic opportunity of primary importance as they combine the ACE-inhibitor, AT1 antagonist and the calcium channel blocker with the best documentation of efficacy in randomized controlled trials.In conclusion, the support of the scientific literature indicates that the rational use of these combinations can certainly represent an optimal choice for the treatment of arterial hypertension according to the best criteria of therapeutic appropriateness.</p>","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 1","pages":"e23-e31"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Domenico Attinà, Marcello Casuso Alvarez, Camilla Sportoletti, Fabio Niro, Luca Bergamaschi, Francesco Angeli, Matteo Armillotta, Carmine Pizzi, Luigi Lovato
{"title":"[Subepicardial hematoma: a rare complication after percutaneous coronary intervention].","authors":"Domenico Attinà, Marcello Casuso Alvarez, Camilla Sportoletti, Fabio Niro, Luca Bergamaschi, Francesco Angeli, Matteo Armillotta, Carmine Pizzi, Luigi Lovato","doi":"10.1714/4394.43962","DOIUrl":"10.1714/4394.43962","url":null,"abstract":"<p><p>We report the case of a 78-year-old patient with acute ST-elevation myocardial infarction treated with primary percutaneous coronary intervention (PCI) of the right coronary artery, subsequently found to have a large subepicardial mass. The patient underwent a non-invasive multimodal diagnostic work-up including cardiac computed tomography and cardiac magnetic resonance imaging, which led to the diagnosis of subepicardial hematoma following coronary perforation during primary PCI. Due to clinical stability and absence of active bleeding sources, the patient was managed conservatively with gradual absorption of the mass and favorable prognostic outcome.</p>","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 1","pages":"71-74"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}