Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft最新文献_第6页

[Effect of anti-glaucoma eyedrops on cell differentiation of the conjunctiva]. [抗青光眼滴眼液对结膜细胞分化的影响]。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

K P Steuhl, M Knorr, A Frohn, H J Thiel

{"title":"[Effect of anti-glaucoma eyedrops on cell differentiation of the conjunctiva].","authors":"K P Steuhl, M Knorr, A Frohn, H J Thiel","doi":"","DOIUrl":"","url":null,"abstract":"After local application of pilocarpine (minimum 1%), timolol (0.5%) or levobunolol (0.5%) to 6 patients, cell differentiation of the conjunctival epithelium was compared to that in 48 healthy persons. The least difference was found after pilocarpine application. The five ultrastructurally defined cell types were found to vary least when compared to the same cell types in normal subjects. The patients treated with timolol and levobunolol showed a reduction in secretory epithelial cells, especially within the conjunctiva bulbi, and a pronounced increase in cells with rough endoplasmatic reticulum. In addition to a loss of desmosomes and zonulae occludentes on the cell surface, a minimum 1-year application of the three antiglaucomatous medications leads to a reduction in the microvilli and microplicae and, particularly in patients treated with beta blockers, to intracellular changes, specifically increased vacuolization and dilation of the rough endoplasmatic reticulum. The latter may be attributable to the action of benzalkonium chloride (present as a preservative in all three eye drops studied) on the superficial epithelial cells. The cytotoxic action of the preservative may be intensified by the simultaneous application of beta blockers due to their destabilizing effect on the tear film.","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 6","pages":"865-9"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12956822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Experience with kerato-prosthetics]. 有角膜修复术的经验。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

B Alberth

引用次数: 0

[Microcoagulation of the fundus. Experimental results of repeated laser pulse exposure]. 眼底微凝。重复激光脉冲曝光的实验结果[j]。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

J Roider, N Michaud, T Flotte, R Birngruber

引用次数: 0

[Bilateral chorioretinitis after infection with Yersinia enterocolitica]. [小肠结肠炎耶尔森菌感染后的双侧绒毛膜视网膜炎]。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

R Osusky, H L Kain

引用次数: 0

[Experimental studies of proliferative vitreoretinopathy]. 增生性玻璃体视网膜病变的实验研究。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

H L Kain

引用次数: 0

[Central vein occlusion as a sequela of spontaneous arteriovenous fistula of the carotid artery to the cavernous sinus]. 【自发性颈动脉到海绵窦的动静脉瘘的后遗症】。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

D Schmidt, M Schumacher

{"title":"[Central vein occlusion as a sequela of spontaneous arteriovenous fistula of the carotid artery to the cavernous sinus].","authors":"D Schmidt, M Schumacher","doi":"","DOIUrl":"","url":null,"abstract":"We found a central retinal vein occlusion in three of nine patients with spontaneous arteriovenous fistulas of the cavernous sinus region. The femoral angiogram displayed a \"low-flow\" fistula from the internal carotid artery and/or dural branches of the external carotid artery into the cavernous sinus in all three patients. Angiographically, occlusion of the superior ophthalmic vein was present in all three patients. The arteriovenous flow of the shunt was directed into the sphenoparietal sinus and into other cerebral veins, but not into the orbit. This is the first angiographic demonstration of occlusion of the superior ophthalmic vein in patients with central retinal vein occlusion. The decrease in blood flow in the superior ophthalmic vein and the central retinal vein occlusion developed several months after the onset of the cavernous fistula. The occurrence of thrombosis is regarded as the consequence of venous stasis in the superior ophthalmic vein. It is assumed that the thrombosis grew retrogradely along the superior ophthalmic vein towards the central retinal vein. The intraocular pressure was not elevated in two of the three patients and therefore not regarded as the cause of the central retinal vein occlusion. Lid erythema and conjunctival hyperemia were pronounced in the acute stage of the fistula formation.","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 6","pages":"683-6"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12956552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Case histories and "medical statistics" 200 years ago--case notes by Jung-Stilling on his cataract operations 1773-1778]. [200年前的病例史和“医学统计”——Jung-Stilling 1773-1778年白内障手术的病例记录]。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

G Berneaud-Kötz

引用次数: 0

[Revision operations in retinal redetachment]. 视网膜再脱离的翻修手术。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

C Jandeck, U Kellner, M H Foerster, A Wessing

引用次数: 0

[Changes in the endothelial cell density after perforating keratoplasty]. 穿孔角膜移植术后内皮细胞密度的变化。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

B Bergmann, M Böhnke, R Winter, J Draeger

引用次数: 0

[Bromocriptine in therapy of chronic recurrent anterior uveitis]. 溴隐亭治疗慢性复发性前葡萄膜炎。

Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft Pub Date : 1991-01-01

M Zierhut, H J Thiel, U Pleyer, R Waetjen, E G Weidle

{"title":"[Bromocriptine in therapy of chronic recurrent anterior uveitis].","authors":"M Zierhut, H J Thiel, U Pleyer, R Waetjen, E G Weidle","doi":"","DOIUrl":"","url":null,"abstract":"In animal studies, bromocriptine (Pravidel) has demonstrated immunosuppression because of inhibition of prolactin. After publication of positive results in the treatment of uveitis in a few case reports and in an uncontrolled study we conducted a double-blind placebo-controlled study in 13 patients with chronic recurrent anterior uveitis who had experienced three or more recurrences during the previous year. Therapy was started gradually during the symptom-free interval and continued for 1 year with 2.5 mg twice daily. Two recurrences or relevant side effects led to discontinuation of the therapy. In the bromocriptine group, 2 of 7 patients had no recurrences during the study period. Two patients had to stop because of two recurrences but, in contrast to earlier recurrences, they responded to local corticosteriod treatment within a few days. The remaining 3 patients (1 with one recurrence, 2 without) had to stop because of the side effects (arterial hypotension, arthritic complaints). In 5 of 6 patients in the placebo group treatment was stopped because of recurrences and in 1 patients because she believed she was experiencing a side effect from bromocriptine (breast atrophy). In summary, bromocriptine seems to have a prophylactic effect on anterior uveitis. Side effects were frequent but mild compared to other immunosuppressives. In case of arterial hypotension, additional therapy could make this drug more tolerable.","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 2","pages":"161-4"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13016396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0