Tabita M. Breitsprecher, Wolf-Dieter Baumgartner, Kevin Brown, Stefan Dazert, Úna Doyle, A. Dhanasingh, W. Grossmann, R. Hagen, P. Van de Heyning, Robert Mlynski, M. Neudert, Gunesh Rajan, K. Rak, V. van Rompaey, J. Schmutzhard, S. Volkenstein, Christiane Völter, Wilhelm Wimmer, M. Zernotti, N. Weiss
{"title":"Effect of Cochlear Implant Electrode Insertion Depth on Speech Perception Outcomes: A Systematic Review","authors":"Tabita M. Breitsprecher, Wolf-Dieter Baumgartner, Kevin Brown, Stefan Dazert, Úna Doyle, A. Dhanasingh, W. Grossmann, R. Hagen, P. Van de Heyning, Robert Mlynski, M. Neudert, Gunesh Rajan, K. Rak, V. van Rompaey, J. Schmutzhard, S. Volkenstein, Christiane Völter, Wilhelm Wimmer, M. Zernotti, N. Weiss","doi":"10.1097/ono.0000000000000045","DOIUrl":"https://doi.org/10.1097/ono.0000000000000045","url":null,"abstract":"\u0000 \u0000 The suitable electrode array choice is broadly discussed in cochlear implantation surgery. Whether to use a shorter electrode length under the aim of structure preservation versus choosing a longer array to achieve a greater cochlear coverage is a matter of debate. The aim of this review is to identify the impact of the insertion depth of a cochlear implant (CI) electrode array on CI users’ speech perception outcomes.\u0000 \u0000 \u0000 \u0000 PubMed was searched for English-language articles that were published in a peer-reviewed journal from 1997 to 2022.\u0000 \u0000 \u0000 \u0000 A systematic electronic search of the literature was carried out using PubMed to find relevant literature on the impact of insertion depth on speech perception. The review was conducted according to the preferred reporting items for systematic reviews and meta-analyses guidelines of reporting. Studies in both, children and adults with pre- or postlingual hearing loss, implanted with a CI were included in this study. Articles written in languages other than English, literature reviews, meta-analyses, animal studies, histopathological studies, or studies pertaining exclusively to imaging modalities without reporting correlations between insertion depth and speech outcomes were excluded. The risk of bias was determined using the “Risk of Bias in Nonrandomized Studies of Interventions” tool. Articles were extracted by 2 authors independently using predefined search terms. The titles and abstracts were screened manually to identify studies that potentially meet the inclusion criteria. The extracted information included: the study population, type of hearing loss, outcomes reported, devices used, speech perception outcomes, insertion depth (linear insertion depth and/or the angular insertion depth), and correlation between insertion depth and the speech perception outcomes.\u0000 \u0000 \u0000 \u0000 A total of 215 relevant studies were assessed for eligibility. Twenty-three studies met the inclusion criteria and were analyzed further. Seven studies found no significant correlation between insertion depth and speech perception outcomes. Fifteen found either a significant positive correlation or a positive effect between insertion depth and speech perception. Only 1 study found a significant negative correlation between insertion depth and speech perception outcomes.\u0000 \u0000 \u0000 \u0000 Although most studies reported a positive effect of insertion depth on speech perception outcomes, one-third of the identified studies reported no correlation. Thus, the insertion depth must be considered as a contributing factor to speech perception rather than as a major decisive criterion.\u0000 \u0000 \u0000 \u0000 This review has been registered in PROSPERO, the international prospective register of systematic reviews (CRD42021257547), available at https://www.crd.york.ac.uk/PROSPERO/.\u0000","PeriodicalId":124165,"journal":{"name":"Otology & Neurotology Open","volume":"529 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138993044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carey D. Balaban, Erin Williams, Cynthia L. Holland, Alexander Kiderman, Anthony P. Kontos, Michael E. Hoffer
{"title":"Statistical Considerations for Subjective Visual Vertical and Subjective Visual Horizontal Assessment in Normal Subjects","authors":"Carey D. Balaban, Erin Williams, Cynthia L. Holland, Alexander Kiderman, Anthony P. Kontos, Michael E. Hoffer","doi":"10.1097/ono.0000000000000044","DOIUrl":"https://doi.org/10.1097/ono.0000000000000044","url":null,"abstract":"\u0000 \u0000 Judgments of the subjective visual vertical (SVV) and subjective visual horizontal (SVH) while seated upright are commonly included in standard clinical test batteries for vestibular function. We examined SVV and SVH data from retrospective control to assess their statistical distributions and normative values for magnitudes of the preset effect, sex differences, and fixed-head versus head-free device platforms for assessment.\u0000 \u0000 \u0000 \u0000 Retrospective clinical SVV and SVH data from 2 test platforms, Neuro-otologic Test Center (NOTC) and the Neurolign Dx 100 (I-Portal Portable Assessment System Nystagmograph) were analyzed statistically (SPSS and MATLAB software) for 408 healthy male and female civilians and military service members, aged 18–50 years.\u0000 \u0000 \u0000 \u0000 No prominent age-related effects were observed. The preset angle effects for both SVV and SVH, and their deviations from orthogonality, agree in magnitude with previous reports. Differences attributable to interactions with device type and sex are of small magnitude. Analyses confirmed that common clinical measure for SVV and SVH, the average of equal numbers of clockwise and counterclockwise preset trials, was not significantly affected by the test device or sex of the subject. Finally, distributional analyses failed to reject the hypothesis of underlying Gaussian distributions for the clinical metrics.\u0000 \u0000 \u0000 \u0000 \u0000 z scores based on these normative findings can be used for objective detection of outliers from normal functional limits in the clinic.\u0000","PeriodicalId":124165,"journal":{"name":"Otology & Neurotology Open","volume":"299 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138991838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Naushin Shabnam Ali, Barry Daniel Long, Nauman F. Manzoor, Aristides Sismanis, Daniel H Coelho
{"title":"Doxycycline-Induced Intracranial Hypertension Presenting as Unilateral Pulsatile Tinnitus","authors":"Naushin Shabnam Ali, Barry Daniel Long, Nauman F. Manzoor, Aristides Sismanis, Daniel H Coelho","doi":"10.1097/ono.0000000000000043","DOIUrl":"https://doi.org/10.1097/ono.0000000000000043","url":null,"abstract":"Pulsatile tinnitus (PT) is increasingly recognized as a cardinal symptom of idiopathic intracranial hypertension (IIH). However, clinicians should remain aware of other causes of nonidiopathic or secondary intracranial hypertension manifesting as PT. We present 2 patients with isolated PT (without accompanying headache, blurred vision, and papilledema) thought to be secondary to tetracycline-induced intracranial hypertension. To our knowledge, these are the first cases of PT as the presenting symptom of this condition. A 41-year-old female (body mass index [BMI] 29 kg/m2) with ocular rosacea was initially treated with minocycline. Shortly after transitioning to oral doxycycline and erythromycin eye ointment, she noted left-sided PT. Her PT resolved after discontinuing doxycycline. In a second case, a 39-year-old female (BMI 19 kg/m2) with acne presented with a three-year history of left-sided PT while on long-term oral doxycycline for many years. She denied visual or auditory changes and atypical headaches. MRI findings were concerning for intracranial hypertension. Three months later, the patient was seen by neuro-ophthalmology, with findings suggesting prior papilledema. The patient reported PT improvement after discontinuing doxycycline. This case series highlights 2 cases of isolated PT as the sole symptom of intracranial hypertension that resolved with tetracycline cessation. The presentation and unexpected improvement following tetracycline discontinuation are atypical compared with previous reports of tetracycline-induced intracranial hypertension. Clinicians should maintain a high index of suspicion for all types of intracranial hypertension (idiopathic and secondary), even in patients with a lower BMI. Current and prior medications should be reviewed when considering the etiology of intracranial hypertension.","PeriodicalId":124165,"journal":{"name":"Otology & Neurotology Open","volume":"37 S4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139248535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. G. Vosbeek, L. Straatman, A. Braat, Bart de Keizer, H. Thomeer, A. Smit
{"title":"Management and Outcomes of Necrotizing Otitis Externa: A Retrospective Cohort Study in a Tertiary Referral Center.","authors":"E. G. Vosbeek, L. Straatman, A. Braat, Bart de Keizer, H. Thomeer, A. Smit","doi":"10.1097/ono.0000000000000042","DOIUrl":"https://doi.org/10.1097/ono.0000000000000042","url":null,"abstract":"Necrotizing otitis externa (NOE) is a rare infection of the ear that causes osteomyelitis. We aimed to evaluate treatment outcomes and the role of imaging in diagnosing and monitoring disease resolution in a single-center study of patients with NOE. In this retrospective cohort study, patients with NOE who were diagnosed and treated in a tertiary otology center in Utrecht, The Netherlands, between January 1, 2013 and August 1, 2022, were included. Data were retrieved from the medical records on demographics, symptoms, physical and diagnostic findings, type and duration of treatment, and course of disease. A total of 24 cases were included. Patients were often elderly (mean age = 75 years) and diabetic (88%). Pseudomonas aeruginosa was the most commonly found microorganism (63%). Twenty-two cases (92%) received intravenous antibiotic treatment, and 7 cases (29%) received additional systemic antifungal treatment. The mean duration of systemic treatment was 29 weeks. In 20 out of 22 cases (91%), imaging was used to determine the end point of treatment. None of the cases with a total resolution of disease activity (n = 5) on 18F-fluorodeoxyglucose-positron emission tomography-computed tomography imaging at the time of cessation of therapy showed clinical relapse, compared with 1 out of 4 cases on gallium single-photon emission computerized tomography. Based on the experience from our center, we demonstrated that patients with NOE can successfully be treated with prolonged systemic treatment. Molecular imaging is reasonably successful for disease evaluation and decision-making on the eradication of disease.","PeriodicalId":124165,"journal":{"name":"Otology & Neurotology Open","volume":"169 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139246580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Hullfish, B. Schachner, Zachary D. Zippi, Brandon Kamrava, S. Angeli
{"title":"Cross-sectional Evaluation of Neurotology Fellowship Directors: A Present-day Snapshot of Leadership","authors":"H. Hullfish, B. Schachner, Zachary D. Zippi, Brandon Kamrava, S. Angeli","doi":"10.1097/ono.0000000000000036","DOIUrl":"https://doi.org/10.1097/ono.0000000000000036","url":null,"abstract":"\u0000 \u0000 To identify demographic, training, and career trends of neurotology fellowship directors (FDs).\u0000 \u0000 \u0000 \u0000 Cross-sectional study.\u0000 \u0000 \u0000 \u0000 United States.\u0000 \u0000 \u0000 \u0000 All 26 neurotology FDs identified using the American Neurotology Society (ANS) ACGME Accredited Neurotology Fellowship Program Directory, accessed November 2021.\u0000 \u0000 \u0000 \u0000 Data were collected via CVs, institutional biographies, and emailed questionnaires. Data collected includes age, gender, race and ethnicity, residency and fellowship training institution, time since training completion until FD, length of time as FD, and Hirsch-index (h-index).\u0000 \u0000 \u0000 \u0000 Twenty-six FDs were identified, and 17/26 (65.4%) FDs responded to the questionnaire. The majority (23/26; 88.5%) were male. The mean age of male and female FDs was 56 versus 47 years, respectively. Of the 17 that responded to the survey, 82.4% (14/17) self-identified as Caucasian. The mean h-index was 25.4. Older age correlated with a higher h-index (r = 0.46, P = 0.019). The duration (mean ± SD, years) from fellowship graduation to FD appointment was 10.7 ± 8.1 and 6.3 ± 4.8 from institutional hire. Six (23.1%) FDs had secondary graduate degrees, and 9 (34.6%) held a leadership position at a national otolaryngology organization.\u0000 \u0000 \u0000 \u0000 This observational study assesses demographic data on current neurotology FDs in the United States with an analysis of gender disparities. The objective measures identified can provide a baseline for growth in FD leadership.\u0000","PeriodicalId":124165,"journal":{"name":"Otology & Neurotology Open","volume":"284 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134399030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. K. Oussoren, R. B. van Leeuwen, T. Schermer, Louise N. F. Poulsen, J. Kardux, T. Bruintjes
{"title":"Cerebral Small Vessel Disease in Elderly Patients With Menière’s Disease","authors":"F. K. Oussoren, R. B. van Leeuwen, T. Schermer, Louise N. F. Poulsen, J. Kardux, T. Bruintjes","doi":"10.1097/ono.0000000000000034","DOIUrl":"https://doi.org/10.1097/ono.0000000000000034","url":null,"abstract":"","PeriodicalId":124165,"journal":{"name":"Otology & Neurotology Open","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125309365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna C Buhle, Hilary C. McCrary, S. Gordon, Kathryn M. Johnson, Eric E Babajanian, Neil S. Patel
{"title":"Expanding Understanding of Electrocochleography in Cochlear Implantation: Auditory Neuropathy Spectrum Disorder With Normal Pure Tone Average","authors":"Anna C Buhle, Hilary C. McCrary, S. Gordon, Kathryn M. Johnson, Eric E Babajanian, Neil S. Patel","doi":"10.1097/ono.0000000000000035","DOIUrl":"https://doi.org/10.1097/ono.0000000000000035","url":null,"abstract":"","PeriodicalId":124165,"journal":{"name":"Otology & Neurotology Open","volume":"219 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115983791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia A. Casazza, Kristen L. Yancey, Jacob B. Hunter
{"title":"The Influence of Activities and Functional Social Support on Adult Cochlear Implant Outcomes","authors":"Julia A. Casazza, Kristen L. Yancey, Jacob B. Hunter","doi":"10.1097/ono.0000000000000033","DOIUrl":"https://doi.org/10.1097/ono.0000000000000033","url":null,"abstract":"","PeriodicalId":124165,"journal":{"name":"Otology & Neurotology Open","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129498620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. C. Cao, T. Hwa, Caitlin Cavarocchi, A. Quimby, Steven J Eliades, M. Ruckenstein, D. Bigelow, O. Choudhri, J. Brant
{"title":"Diagnostic Yield and Utility of Radiographic Imaging in the Evaluation of Pulsatile Tinnitus: A Systematic Review","authors":"A. C. Cao, T. Hwa, Caitlin Cavarocchi, A. Quimby, Steven J Eliades, M. Ruckenstein, D. Bigelow, O. Choudhri, J. Brant","doi":"10.1097/ono.0000000000000030","DOIUrl":"https://doi.org/10.1097/ono.0000000000000030","url":null,"abstract":"","PeriodicalId":124165,"journal":{"name":"Otology & Neurotology Open","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133257885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexandra Arambula, Shoujun Gu, A. Warnecke, H. Schmitt, H. Staecker, M. Hoa
{"title":"In Silico Localization of Perilymph Proteins Enriched in Meńier̀e Disease Using Mammalian Cochlear Single-cell Transcriptomics","authors":"Alexandra Arambula, Shoujun Gu, A. Warnecke, H. Schmitt, H. Staecker, M. Hoa","doi":"10.1097/ono.0000000000000027","DOIUrl":"https://doi.org/10.1097/ono.0000000000000027","url":null,"abstract":"","PeriodicalId":124165,"journal":{"name":"Otology & Neurotology Open","volume":"98 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122586478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}