European Spine Journal最新文献

{"title":"Unveiling the kinetic harmony between the hip and spine through Roussouly classification in healthy volunteers.","authors":"Masaki Sakamoto, Mitsuru Takemoto, Youngwoo Kim, Bungo Otsuki, Yu Shimizu, Satoshi Soga, Hiroyuki Tokuyasu","doi":"10.1007/s00586-025-08979-7","DOIUrl":"https://doi.org/10.1007/s00586-025-08979-7","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological interventions for depression during post-acute inpatient rehabilitation after traumatic or non-traumatic spinal injury: a matched-case control study.","authors":"Alejandro García-Rudolph, Maria Dolors Soler, Anna Gilabert, Eloy Opisso, Joan Sauri","doi":"10.1007/s00586-025-08950-6","DOIUrl":"https://doi.org/10.1007/s00586-025-08950-6","url":null,"abstract":"<p><strong>Purpose: </strong>Addressing a significant gap in post-acute research and recognizing the high prevalence of depression (22.2%) in people with spinal cord injury (SCI), this study focuses on the vital role of psychosocial care. We examine and compare the biopsychosocial characteristics of two groups of inpatients admitted to a rehabilitation unit within two months post-injury: those with depression at admission and those without. Our objectives are: (i) to conduct a broad biopsychosocial comparison between these two groups across the entire cohort, and (ii) to perform a matched comparison within a subgroup, controlled for age, time from injury to admission, and functional independence. In both comparisons, we assess the total number and types of psychological interventions received by each group.</p><p><strong>Methods: </strong>We conducted a retrospective observational study on 1,147 patients (18.2% with depression at admission) admitted to a specialized hospital between 2005 and 2023. Depression was measured using the Hospital Anxiety and Depression Scale (HADS), and independence in activities of daily living (ADLs) was assessed using the motor Functional Independence Measure-subscale (mFIM). Patients were categorized at admission into two groups based on their HADS scores: the Normal-HADS group (NDG, no depression) and the Border-HADS or Case-HADS group (DG, depression). We compared 209 patients in the DG to: (i) all 938 patients in the NDG, and (ii) a matched subset of 209 NDG patients based on age, mFIM at admission, and time from injury to admission.</p><p><strong>Results: </strong>(i) No significant differences were found between the NDG and DG in age at injury (49.6 vs. 48.3), proportion of non-traumatic etiologies (50.9% vs. 51.2%), complete injuries (28.5% vs. 27.8%), or tetraplegia (33.9% vs. 39.7%). However, while NDG scored significantly higher in mFIM at admission and discharge, DG showed higher mFIM efficiency. The mean total number of psychological interventions was also higher in DG (7.5 vs. 6.2) along with the mean number of psychotherapy interventions (5.9 vs. 5.0). (ii) NDG had a significantly longer length of stay, but DG exhibited higher mFIM efficiency. No significant differences were noted between groups in the mean number of psychological interventions or any of the six types of interventions. Socioeconomic comparisons showed a higher proportion of blue-collar workers in DG (64.1% vs. 35.3%) and white-collar workers in NDG (36.2% vs. 13.9%). Low education (< 9 years) was more prevalent in DG (61.8% vs. 50.0%), and a stable, sufficient income was more common in NDG (75.1% vs. 54.4%).</p><p><strong>Conclusions: </strong>In the matched groups, despite socioeconomic disadvantages and shorter hospital stays, the DG showed higher mFIM efficiency due to shorter stays rather than greater functional gains. Both groups received similar psychological interventions, yet some NDG patients developed depression and anxiety, u","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and imaging characteristics of giant cell tumor in patients aged 18 and below.","authors":"Songbo Zhao, Chenglong Zhou, Ruitao Li, Fantao Zhang, Shengqiang Ye, Hui Wang, Wenjin Qu, Yedong Xin, Wei Su","doi":"10.1007/s00586-025-08915-9","DOIUrl":"https://doi.org/10.1007/s00586-025-08915-9","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the clinical and imaging characteristics of giant cell tumors (GCT) in patients aged 18 and under.</p><p><strong>Methods: </strong>This retrospective study analyzed clinical and imaging data from 12 patients aged 18 and below with histopathologically confirmed GCT, treated at xxx hospital from January 2015 to December 2023. Collected data included patient demographics, clinical presentation, anatomical tumor location, and imaging features from X-rays, CT scans, and MRI. Histopathological examination and immunohistochemistry were performed to confirm diagnoses and assess tumor characteristics.</p><p><strong>Results: </strong>The study included 12 patients (6 males, 6 females) with a mean age of 15.5 years. The most common presenting symptoms were localized pain and swelling. The proximal tibia was the most frequently affected site. Imaging studies consistently showed osteolytic bone destruction with features such as eccentric growth patterns, sclerotic margins, periosteal reaction, and cystic changes. Pathological fractures were noted in five patients. MRI provided detailed insights into the internal architecture of the tumors, including fluid-fluid levels. Histopathology confirmed the presence of multinucleated giant cells within a stromal background. Immunohistochemical analysis showed that RANKL, VEGF, MMP-9, and Ki-67 were variably expressed across cases, with statistically higher expression levels of RANKL and MMP-9 observed in patients with pathological fractures and open epiphyseal plates, respectively.</p><p><strong>Conclusion: </strong>GCT in patients aged 18 and under presents distinct clinical and imaging features that are crucial for accurate diagnosis and effective treatment planning. Recognizing these characteristics is essential for managing this rare but significant bone tumor in the pediatric and adolescent population.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of proton pump inhibitor use on fusion rates following single-level lumbar spinal fusion surgery.","authors":"Yu Chang, Yu-Shiuan Lin, Chih-Yuan Huang, Ming-Tsung Chuang, Kuan-Yu Chi, Junmin Song, Hong-Min Lin","doi":"10.1007/s00586-025-08977-9","DOIUrl":"https://doi.org/10.1007/s00586-025-08977-9","url":null,"abstract":"<p><strong>Purpose: </strong>Lumbar spinal fusion surgery is a common treatment for degenerative spinal conditions. While proton pump inhibitors (PPIs) are widely prescribed for acid-related disorders, emerging evidence suggests that PPI use may negatively affect bone health, potentially influencing spinal fusion outcomes. This study evaluates the impact of postoperative proton pump inhibitor (PPI) use on fusion rates following single-level lumbar spinal fusion surgery.</p><p><strong>Methods: </strong>Data were obtained from the Global Collaborative Network on the TriNetX platform. Patients undergoing single-level lumbar fusion were identified using ICD and CPT codes. Propensity score matching was employed to balance demographics and comorbidities between PPI users and non-users. Postoperative PPI use was defined as continuous use for at least three months following surgery. Non-fusion was identified using ICD-10 code M96.0 at six months, one year, and two years post-surgery. Odds ratios (OR) and 95% confidence intervals (CI) were calculated to assess the risk of pseudarthrosis.</p><p><strong>Results: </strong>The study included 3,857 PPI users and 4,4291 non-users, reduced to 3,847 in each group after propensity score matching. PPI users showed a significantly higher risk of non-fusion at six months (OR: 1.82, 95% CI: 1.54-2.16), one year (OR: 2.08, 95% CI: 1.78-2.44), and two years (OR: 2.33, 95% CI: 2.01-2.71) compared to non-users.</p><p><strong>Conclusion: </strong>The study indicates that postoperative PPI use is linked to a higher risk of non-fusion after lumbar spinal fusion surgery. Clinicians may need to weigh the benefits of postoperative PPI use against its potential impact on bone healing.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standardized spinal MRI protocol: diagnosing spontaneous intracranial hypotension and correlating with brain MRI.","authors":"Yu Sung Yoon, Eun Kyung Khil, Sang Won Jo, Seun Ah Lee, Soo-Jin Cho","doi":"10.1007/s00586-025-08973-z","DOIUrl":"https://doi.org/10.1007/s00586-025-08973-z","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate a standardized cervical-thoracic-lumbar (CTL) contrast-enhanced (CE)-MRI protocol for spinal findings in spontaneous intracranial hypotension (SIH) and their correlation with brain MRI.</p><p><strong>Methods: </strong>This retrospective study included SIH-suspected patients who underwent spine MRI from March 2019 to February 2023. Diagnosis was based on clinical criteria, using a 3T MRI with a standardized spine protocol. MRI diagnostic criteria included spinal (e.g., spinal longitudinal epidural fluid collection [SLEC], dural enhancement [DE]) and brain findings (four qualitative methods including venous sinus engorgement [VSE], pachymeningeal enhancement [PE], and brain sagging [BS] as confirmatory diagnostic criteria; and four quantitative methods). Patients were classified into Group 1 (brain MRI-positive showing VSE, PE or BS) and Group 2 (brain MRI-negative). Demographics and MRI findings were compared in both groups using t-tests or chi-square statistics.</p><p><strong>Results: </strong>Among 53 SIH patients, 42 with spine MRI-positive findings underwent brain MRI (mean age 43.95 ± 12.26 years, 66.7% female), with 27 in Group 1 and 15 in Group 2. Group 1 demonstrated significantly wider sagittal and axial extents of SLEC (full range: 85.2%, circumferential: 82.1%; p < 0.001, p = 0.011), and a higher prevalence of the C1-2 sign, while Group 2 exhibited these features less frequently (85.2% vs. 53.3%, p = 0.024). Brain MRI findings in Group 1 included VSE (92.6%), PE (66.7%), and BS (7.4%), with subdural fluid collection also higher (37.0%, p = 0.007). Other brain parameters showed no significant differences.</p><p><strong>Conclusion: </strong>The standardized CTL CE-MRI protocol enables comprehensive SIH diagnosis, when brain MRI findings are negative or equivocal.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of lumbosacral transitional vertebrae on the distribution and healing of lumbar spondylolysis.","authors":"Mitsuru Asukai, Tomohiro Banno, Mitsuhiro Namba, Hiroshi Nakamura, Reina Murai, Yuki Takeuchi, Akitaka Kurihara, Hideyuki Murata, Masashi Abe, Yukihiro Matsuyama","doi":"10.1007/s00586-025-08982-y","DOIUrl":"https://doi.org/10.1007/s00586-025-08982-y","url":null,"abstract":"<p><strong>Purpose: </strong>Lumbosacral transitional vertebra (LSTV) are a common anatomical variant of the lumbosacral junction that has been associated with various spinal disorders. However, no prior studies have examined the relationship between LSTV and lumbar spondylolysis. Therefore, the aim of this study was to elucidate the prevalence of LSTV and assess its impact on the affected spinal level and bone union rate in patients with lumbar spondylolysis.</p><p><strong>Methods: </strong>This study retrospectively analyzed data from 346 patients (270 boys) aged ≤ 18 years diagnosed with lumbar spondylolysis between January 2012 and December 202. The affected spinal level was assessed in all 346 patients. Bone union was evaluated in 284 patients with very early, early, or progressive lesions who received conservative treatment. LSTV was assessed using the Castellvi classification, and patients were categorized into the LSTV and control groups based on the presence and absence of LSTV, respectively. Statistical analyses were performed to compare the distribution of affected spinal levels and bone union rates between groups.</p><p><strong>Results: </strong>Herein, the prevalence of LSTV in patients with lumbar spondylolysis was 21.1%. The incidence of spondylolysis at L3 and L4 was significantly higher in the LSTV group (L3: 20.5%, L4: 43.8%, and L5: 35.6%) than in the control group (L3: 4.8%, L4: 27.5%, and L5: 67.8%). No significant differences in bone union rates were observed between the two groups (LSTV: 100%, 94.8%, and 47.1%; control: 94.5%, 92.3%, and 49.5% in the very early, early, and progressive stages, respectively).</p><p><strong>Conclusion: </strong>In patients with LSTV, spondylolysis is more likely to occur at L4 or a level more cranial than L5. However, the presence of the LSTV does not significantly affect the bone union rate.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Answer to the letter to the editor of B. Wang, et al. concerning \"Impact of erector spinae plane block on postoperative recovery quality in spinal surgery: a systematic review and meta-analysis\" by Zhang L, et al. (Eur spine J [2025]: doi: 10.1007/s00586-025-08810-3).","authors":"Longyi Zhang, Linlin Chen, Ying Xie","doi":"10.1007/s00586-025-08940-8","DOIUrl":"https://doi.org/10.1007/s00586-025-08940-8","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144156632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient outcomes and surgical strategies in revision cervical arthroplasty following M6-C™ disc-related osteolysis.","authors":"Matthew Scott-Young, David Nielsen, Sukhman Riar, Evelyne Rathbone","doi":"10.1007/s00586-025-08926-6","DOIUrl":"https://doi.org/10.1007/s00586-025-08926-6","url":null,"abstract":"<p><strong>Purpose: </strong>Periprosthetic osteolysis from the M6-C™ Artificial Cervical Disc (Orthofix, Lewisville, Texas) has become a significant issue, sometimes requiring revision spine surgery (RSS). This study evaluates patient-reported outcome measures (PROMs) and revision strategies for managing device-related wear and osteolysis.</p><p><strong>Methods: </strong>PROMs, including the Visual Analogue Scale (VAS) for neck/arm pain and the Neck Disability Index (NDI), were analyzed at pre-index surgery (T1), pre-RSS (T2), and final follow-up (T3). Osteolysis severity was graded radiographically. A control group who underwent primary M6-C cervical total disc replacement (CTDR) without RSS was included for comparison.</p><p><strong>Results: </strong>Of 53 patients with M6-C CTDR, 19 (35.9%) required RSS due to osteolysis. Osteolysis grades included Grade 1 (4 patients), Grade 2 (7 patients), Grade 3 (3 patients), and Grade 4 (5 patients). Revision strategies included removal and anterior fusion, requiring vertebrectomy for Grade 4 cases; revisions to a different CTDR prosthesis were reserved for Grades 1-3. The RSS group showed significant VAS neck pain improvement at T3 (mean = 36.2 points, p < 0.001), exceeding the minimum clinically important difference (MCID). However, VAS arm pain and NDI did not meet MCID thresholds. The control group showed clinically significant improvements across all PROMs. At T2, the RSS group had a higher disability (NDI, p = 0.027) than the controls.</p><p><strong>Conclusion: </strong>Revision surgery for M6-C osteolysis improves neck pain, not arm pain or disability. Early detection and tailored revision strategies are crucial to optimize patient outcomes and mitigate osteolysis-related disability.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of idiopathic normal pressure hydrocephalus in patients with degenerative cervical myelopathy.","authors":"Jim Yu, Satoshi Kodama, Koji Nakajima, So Kato, Hideki Nakamoto, Hiroyasu Kodama, Katsuyuki Sasaki, Hiroyuki Nakarai, Junya Miyahara, Masashi Hamada, Hirokazu Takami, Hiroaki Abe, Masahiko Sumitani, Yuki Taniguchi, Sakae Tanaka, Yasushi Oshima","doi":"10.1007/s00586-025-08945-3","DOIUrl":"https://doi.org/10.1007/s00586-025-08945-3","url":null,"abstract":"<p><strong>Purpose: </strong>Degenerative cervical myelopathy (DCM) and idiopathic normal pressure hydrocephalus (iNPH) share symptoms such as gait disturbance and urinary dysfunction, especially in the elderly. While the incidence of DCM in patients with iNPH is reported, the prevalence of iNPH in patients with DCM remains unclear. This study investigates the prevalence of iNPH in DCM patients.</p><p><strong>Methods: </strong>This retrospective cohort study included 83 patients undergoing decompression surgery for DCM between April 2018 and March 2023. Brain MRI performed within three years prior to surgery was analyzed. Patients were categorized into two groups based on the Evans Index (EI): those with EI > 0.3 were classified as the Suspected-iNPH group, and those with EI ≤ 0.3 as the Non-iNPH group. Pre- and postoperative Japanese Orthopedic Association (JOA) scores and Patient-Reported Outcomes (PROs), including the Neck Disability Index (NDI), EuroQOL-5D (EQ-5D), Core Outcome Measure Index (COMI), and Numerical Rating Scale (NRS) for pain, were compared. Suspected-iNPH cases underwent further analysis to identify disproportionately enlarged subarachnoid space hydrocephalus (DESH).</p><p><strong>Results: </strong>Thirty-one patients (37%) were classified as Suspected-iNPH, who were significantly older (p = 0.01). No significant differences were found in pre- or postoperative JOA scores, and PROs. DESH was identified in 6 patients (7%), with 2 diagnosed as probable-iNPH based on cerebrospinal fluid tap tests.</p><p><strong>Conclusions: </strong>A notable proportion of elderly DCM patients exhibit ventricular enlargement and DESH, suggesting a potential overlap with iNPH. Brain MRI should be considered for elderly DCM patients, particularly when neurological symptoms deviate from typical patterns.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Answer to the letter to the editor of X. Zhang, et al. concerning \"AI versus the spinal surgeons in the management of controversial spinal surgery scenarios\" by Mehmet, S. et al. (Eur spine J [2025]: doi.org/10.1007/s00586-025-08825-w).","authors":"Saylan Mehmet, Mohamed Nabil Elmarawany, Ian Harding, Andrew James Bowey, John Andrews, Daniel Chan, Raveen Jayasuriya, Shreya Srinivas, James Tomlinson, Edward Bayley, Michael Paul Grevitt, Stuart James, Alwyn Jones, Michael J H McCarthy","doi":"10.1007/s00586-025-08938-2","DOIUrl":"https://doi.org/10.1007/s00586-025-08938-2","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144156800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}