European Spine Journal最新文献

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Letter to the editor concerning "Machine learning-based models for outcome prediction in skull base and spinal chordomas: a systematic review and meta-analysis" by B. Hajikarimloo, et al. (Eur spine J [2025]: doi: 10.1007/s00586-025-09053-y). 关于“基于机器学习的颅底和脊索瘤预后预测模型:系统回顾和荟萃分析”的致编辑信,B. Hajikarimloo,等。[2025]:doi: 10.1007/s00586-025-09053-y。
IF 2.6 3区 医学
European Spine Journal Pub Date : 2025-07-07 DOI: 10.1007/s00586-025-09115-1
Tiantaixi Tu
{"title":"Letter to the editor concerning \"Machine learning-based models for outcome prediction in skull base and spinal chordomas: a systematic review and meta-analysis\" by B. Hajikarimloo, et al. (Eur spine J [2025]: doi: 10.1007/s00586-025-09053-y).","authors":"Tiantaixi Tu","doi":"10.1007/s00586-025-09115-1","DOIUrl":"https://doi.org/10.1007/s00586-025-09115-1","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Comparison of two ultrasound methods from Scolioscan® for measuring spinal curvature: spinous processes (SP) versus transverse processes (TP). 校正:比较两种超声方法从脊柱侧凸®测量脊柱曲度:棘突(SP)与横突(TP)。
IF 2.6 3区 医学
European Spine Journal Pub Date : 2025-07-07 DOI: 10.1007/s00586-025-09105-3
Lea Klara Zimmermann, Christian Hülstrunk, Benjamin Schmitt, Gaby Baron, Rebecca Roth, Axel Hennes, Peter Raab, Omar Zabar
{"title":"Correction: Comparison of two ultrasound methods from Scolioscan® for measuring spinal curvature: spinous processes (SP) versus transverse processes (TP).","authors":"Lea Klara Zimmermann, Christian Hülstrunk, Benjamin Schmitt, Gaby Baron, Rebecca Roth, Axel Hennes, Peter Raab, Omar Zabar","doi":"10.1007/s00586-025-09105-3","DOIUrl":"https://doi.org/10.1007/s00586-025-09105-3","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Geographic, personal and clinical determinants of brace-wearing time in adolescents with idiopathic scoliosis. 青少年特发性脊柱侧凸戴牙套时间的地理、个人和临床决定因素。
IF 2.6 3区 医学
European Spine Journal Pub Date : 2025-07-07 DOI: 10.1007/s00586-025-09086-3
Alessandra Negrini, Sabrina Donzelli, Giulia Rebagliati, Giulia Fregna, Michele Romano, Fabio Zaina, Stefano Negrini
{"title":"Geographic, personal and clinical determinants of brace-wearing time in adolescents with idiopathic scoliosis.","authors":"Alessandra Negrini, Sabrina Donzelli, Giulia Rebagliati, Giulia Fregna, Michele Romano, Fabio Zaina, Stefano Negrini","doi":"10.1007/s00586-025-09086-3","DOIUrl":"https://doi.org/10.1007/s00586-025-09086-3","url":null,"abstract":"<p><strong>Purpose: </strong>Adherence to brace treatment is crucial for its effectiveness in AIS. The study aimed to verify the impact of geographic, personal and clinical variables on adherence to brace wear.</p><p><strong>Methods: </strong>Design: retrospective cross-sectional study of consecutively collected participants at a tertiary referral institute.</p><p><strong>Inclusion criteria: </strong>AIS, one-year of follow-up after bracing, and use of a thermal sensor. The outcome was adherence and tested predictors were age, gender, ATR, TRACE, Cobb, curve type, Risser, and back pain at baseline, brace type and prescription time, income, living in the North, Centre, or South of Italy, city of residence size, distance from the sea, and height above sea level. The chi 2 test was used to investigate the association between the categories and adherence. The logistic regression model tested the predictors. STATA 17.0 MP was used.</p><p><strong>Results: </strong>We included 1904 adolescents, age 13.8 ± 1.6 (1597 females), worse scoliosis curve 35 ± 11° Cobb. The prevalence of good compliers, with more than 75% of the prescribed dosage, was 90.8%. Factors associated with higher adherence were living in the North of Italy (p = 0.003), prescription > 20 h per day (p = 0.008), female gender (p = 0.008), younger age and lower Risser sign (age 10 to 13: p = 0.000; Risser 0-1: p = 0.013). The regression model explained 4% of the variability.</p><p><strong>Conclusion: </strong>Living in the North of Italy, longer hours of brace prescription, female gender, younger age, and lower Risser sign increased adherence to brace wear. Nevertheless, there are other unknown factors that contribute to the explanation of adherence in this highly compliant population.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The influence of decorin, a potential pro-inflammatory stimulant, on the mechanical properties of the annulus fibrosus. 一种潜在的促炎刺激物——装饰素对纤维环力学特性的影响。
IF 2.6 3区 医学
European Spine Journal Pub Date : 2025-07-07 DOI: 10.1007/s00586-025-09110-6
Sabrina I Sinopoli, Sarah K W Au, Stephanie J DeWitte-Orr, Diane E Gregory
{"title":"The influence of decorin, a potential pro-inflammatory stimulant, on the mechanical properties of the annulus fibrosus.","authors":"Sabrina I Sinopoli, Sarah K W Au, Stephanie J DeWitte-Orr, Diane E Gregory","doi":"10.1007/s00586-025-09110-6","DOIUrl":"https://doi.org/10.1007/s00586-025-09110-6","url":null,"abstract":"<p><strong>Purpose: </strong>Structural disruption of the intervertebral disc can result in fragmentation of extracellular matrix components such as decorin, which has the capacity to mount an inflammatory response. However, it is unknown if decorin also alters the biomechanical properties of the intervertebral disc, and specifically the annulus fibrosus. Therefore, the purpose of this study was to investigate the potential of decorin to stimulate a pro-inflammatory environment and alter the mechanical integrity and tensile properties of a rat tail annulus.</p><p><strong>Methods: </strong>Sixty annulus fibrosus rings were dissected from 15 rat tails and randomized into three culture conditions: (i) control; (ii) 0.5 µg/mL bovine decorin (low dose); (iii) 5 µg/mL bovine decorin (high dose). Samples were cultured for 6 days then tested via a tensile mechanical testing system. IL-6 and MIP-2 concentration in the culture media were quantified via enzyme-linked immunosorbent assays at day 6.</p><p><strong>Results: </strong>IL-6 and MIP-2 were present in the media after six days of culture but did not differ between conditions. Decorin did, however, impact a number of tensile properties of the annulus. Specifically, the high dose of decorin resulted in greater toe region strain (p < 0.001) and greater failure strain (p < 0.001) as well as greater initial failure stress (p = 0.024) and maximum stress (p = 0.001).</p><p><strong>Discussion: </strong>The observed increase in annulus strength may be a result of reorganization of the load-bearing collagen fibres while the increased strain may be due to degradation of other matrix proteins. Future work is necessary to further elucidate the complex relationship between decorin exposure and altered tissue mechanics.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prediction model of recurrence in patients with lumbar disc herniation after unilateral biportal endoscopy spinal surgery- XGBoost machine learning model can be interpreted based on SHAP. 单侧双门静脉内窥镜脊柱手术后腰椎间盘突出症复发预测模型——XGBoost机器学习模型可基于SHAP进行解释。
IF 2.6 3区 医学
European Spine Journal Pub Date : 2025-07-07 DOI: 10.1007/s00586-025-09032-3
Yi Rong, Hao Yu, Zhen Hua, Jian-Feng Chen, Jian-Wei Wang
{"title":"Prediction model of recurrence in patients with lumbar disc herniation after unilateral biportal endoscopy spinal surgery- XGBoost machine learning model can be interpreted based on SHAP.","authors":"Yi Rong, Hao Yu, Zhen Hua, Jian-Feng Chen, Jian-Wei Wang","doi":"10.1007/s00586-025-09032-3","DOIUrl":"https://doi.org/10.1007/s00586-025-09032-3","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spinopelvic fixation surgery in relation to the femoroacetabular impingement syndrome under the ultrasound. 超声下脊柱骨盆固定手术与股髋臼撞击综合征的关系。
IF 2.6 3区 医学
European Spine Journal Pub Date : 2025-07-07 DOI: 10.1007/s00586-025-09055-w
Takahiro Kozaki, Takuhei Kozaki, Yuyu Ishimoto, Hiroshi Iwasaki, Hiroshi Hashizume, Shunji Tsutsui, Masanari Takami, Keiji Nagata, Masatoshi Teraguchi, Daisuke Nishiyama, Daisuke Fukui, Manabu Yamanaka, Tsuyoshi Deguchi, Ryuichiro Nakanishi, Ryo Miyake, Yuta Yamamoto, Hiroshi Yamada
{"title":"Spinopelvic fixation surgery in relation to the femoroacetabular impingement syndrome under the ultrasound.","authors":"Takahiro Kozaki, Takuhei Kozaki, Yuyu Ishimoto, Hiroshi Iwasaki, Hiroshi Hashizume, Shunji Tsutsui, Masanari Takami, Keiji Nagata, Masatoshi Teraguchi, Daisuke Nishiyama, Daisuke Fukui, Manabu Yamanaka, Tsuyoshi Deguchi, Ryuichiro Nakanishi, Ryo Miyake, Yuta Yamamoto, Hiroshi Yamada","doi":"10.1007/s00586-025-09055-w","DOIUrl":"https://doi.org/10.1007/s00586-025-09055-w","url":null,"abstract":"<p><strong>Purpose: </strong>Spinopelvic fixation surgery is widely used for adult spinal deformity, but its impact on hip joint pathology remains unclear. This study investigates its association with femoroacetabular impingement syndrome (FAIS) using ultrasonography.</p><p><strong>Methods: </strong>This retrospective study included 80 patients (160 hips) who underwent spinal fusion for adult spinal deformity. Patients were categorized based on sacroiliac joint fixation into fixation (group F) and non-fixation (group N). Ultrasonography was performed to assess hip morphology, including labral degeneration, cam lesions, and acetabular osteophytes. The Kellgren-Lawrence (KL) grade, and alpha angle were measured on standing radiographs. The anterior impingement test was conducted to evaluate clinical symptoms, and prevalence was statistically compared.</p><p><strong>Results: </strong>We analyzed 151 hips (26 males, 125 females) with a mean follow-up of 52.7 ± 39.6 months. After excluding 27 hips with advanced hip osteoarthritis (KL grade ≥ 2), labral degeneration (69.5% vs. 37.9%, p = 0.0076) and cam lesions (30.5% vs. 6.9%, p = 0.01) were significantly more prevalent in group F than group N. The mean alpha angle did not significantly differ between two groups at the time of surgery, but significantly greater in group F compared to group N (48.7 ± 3.9° vs. 46.7 ± 4.7°, p = 0.01) at final follow-up.</p><p><strong>Conclusion: </strong>Spinopelvic fixation may contribute to FAIS-related hip abnormalities by increasing mechanical stress. Ultrasonography may aid in early detection of hip joint changes after adult spinal deformity surgery.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Length of mobile phone use mediating the effect of major depression on low back pain/sciatica: a mendelian randomization study. 手机使用时长介导重度抑郁对腰痛/坐骨神经痛的影响:一项孟德尔随机研究
IF 2.6 3区 医学
European Spine Journal Pub Date : 2025-07-05 DOI: 10.1007/s00586-025-09099-y
Wangmi Liu, Xiaxuan Zhang, Yuejian Wang, Dechao Chen, Kongjun Zhao, Jianjun Liang
{"title":"Length of mobile phone use mediating the effect of major depression on low back pain/sciatica: a mendelian randomization study.","authors":"Wangmi Liu, Xiaxuan Zhang, Yuejian Wang, Dechao Chen, Kongjun Zhao, Jianjun Liang","doi":"10.1007/s00586-025-09099-y","DOIUrl":"https://doi.org/10.1007/s00586-025-09099-y","url":null,"abstract":"<p><strong>Purpose: </strong>Accumulating evidence indicates an association between major depression (MD) and the occurrence of low back pain/sciatica (LBP/S). In order to examine this association, we conducted a Mendelian randomization (MR) study, further evaluating the extent to which the length of mobile phone use mediates the impact of MD on the risk of developing LBP/S.</p><p><strong>Methods: </strong>Genetic instruments and association estimates for MD, LBP/S, and length of mobile phone use were extracted from existing Genome-wide Association Study (GWAS) summary data. Bidirectional two-sample MR analyses were conducted to investigate the influence of MD on the risk of LBP/S. Furthermore, MR mediation analyses were executed to evaluate whether the length of mobile phone use mediates any effect of MD on LBP/S.</p><p><strong>Results: </strong>MR analyses showed that a higher genetic risk for MD increased the odds of LBP/S (odds ratio [OR] 1.241; 95% confidence interval [CI], 1.065-1.446). The mediation analysis, employing a two-step MR approach, indicated that the observed effect was partially mediated by the length of mobile phone use, accounting for a mediated proportion of 12.0% (95% CI, 2.3-25.0%).</p><p><strong>Conclusion: </strong>These findings may serve as a foundation for devising preventive strategies and interventions aimed at regulating the length of mobile phone use for individuals grappling with LBP/S in the context of MD.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors associated with failure to achieve Scoliosis Research Society-22r minimal clinically important difference despite achieving optimal global alignment in adult spinal deformity surgery. 尽管在成人脊柱畸形手术中实现了最佳的整体对齐,但未能实现脊柱侧凸研究协会-22r的相关因素的临床重要差异最小。
IF 2.6 3区 医学
European Spine Journal Pub Date : 2025-07-04 DOI: 10.1007/s00586-025-09043-0
Se-Jun Park, Jin-Sung Park, Dong-Ho Kang, Yun-Mi Lim, Hyun-Jun Kim, Chong-Suh Lee
{"title":"Factors associated with failure to achieve Scoliosis Research Society-22r minimal clinically important difference despite achieving optimal global alignment in adult spinal deformity surgery.","authors":"Se-Jun Park, Jin-Sung Park, Dong-Ho Kang, Yun-Mi Lim, Hyun-Jun Kim, Chong-Suh Lee","doi":"10.1007/s00586-025-09043-0","DOIUrl":"https://doi.org/10.1007/s00586-025-09043-0","url":null,"abstract":"<p><strong>Purpose: </strong>To identify factors associated with failure to achieve the minimal clinically important difference (MCID) in the Scoliosis Research Society-22r (SRS-22r) despite achieving optimal global alignment in adult spinal deformity (ASD) surgery.</p><p><strong>Methods: </strong>This study analyzed consecutive patients who underwent ≥ 5-level fusion for ASD and achieved optimal global alignment at a minimum of 2-year follow-up. Patients were divided into two groups based on whether they reached the MCID threshold (1.05) for the SRS-22r subtotal score. Demographic, surgical, radiographic, and mechanical complication data were compared between the groups. Multivariate logistic regression analysis was performed to identify independent predictors of MCID failure.</p><p><strong>Results: </strong>A total of 259 patients were included in this study (female, 88.0%; mean age, 69.0 years; mean follow-up duration, 36.5 months). At the final follow-up, 117 patients (45.2%) failed to achieve the SRS-22r MCID. Multivariate analysis identified a high preoperative SRS-22r pain score (odds ratio [OR] = 1.988, P = 0.003) and high preoperative self-image score (OR = 2.597, P = 0.006) as independent predictors of MCID failure. The cutoff values for preoperative pain and self-image scores were 2.50 and 1.70, respectively (area under the curve [AUC] = 0.674 for pain subdomain; AUC = 0.656 for self-image subdomain).</p><p><strong>Conclusions: </strong>Despite achieving optimal global alignment, nearly half of the patients (45.2%) failed to reach the MCID in the SRS-22r score. Higher preoperative SRS-22r pain and self-image scores were significant predictors of failure. Therefore, these two factors should be primary considerations in surgical decision-making to improve patient-reported outcomes.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144559616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between eveningness and low back pain among public servants in Japan: a cross-sectional analysis of the Aichi Workers' Cohort Study. 日本公务员夜间活动与腰痛之间的关系:爱知工人队列研究的横断面分析。
IF 2.6 3区 医学
European Spine Journal Pub Date : 2025-07-03 DOI: 10.1007/s00586-025-09048-9
Mika Matsunaga, Ryusei Okegawa, Nobuyuki Fujita, Tsuyoshi Kitajima, Hiroshi Yatsuya, Atsuhiko Ota
{"title":"Association between eveningness and low back pain among public servants in Japan: a cross-sectional analysis of the Aichi Workers' Cohort Study.","authors":"Mika Matsunaga, Ryusei Okegawa, Nobuyuki Fujita, Tsuyoshi Kitajima, Hiroshi Yatsuya, Atsuhiko Ota","doi":"10.1007/s00586-025-09048-9","DOIUrl":"https://doi.org/10.1007/s00586-025-09048-9","url":null,"abstract":"<p><strong>Purpose: </strong>Low back pain (LBP) is a common occupational health problem. Chronotype, an individual's preferred timing of activity and sleep, has been linked to pain perception. Previous studies have found a potential association between chronotype and LBP, although the findings were limited by small sample sizes and restricted population types. We investigated the association between evening chronotype (eveningness) and LBP in a cohort comprising public servants of various ages.</p><p><strong>Methods: </strong>We conducted a cross-sectional analysis of 4728 full-time public servants in Japan. LBP was assessed using a self-reported question. Individuals' chronotypes were determined using the reduced Morningness-Eveningness Questionnaire. The association between chronotype and LBP was analyzed using the chi-squared test and multiple logistic regression models adjusted for age, sex, occupation, overtime work, use of the internet/email, body mass index, smoking status, exercise habits, sedentary behavior, sleep duration, sleep medication use, and depressive symptoms.</p><p><strong>Results: </strong>In total, 30% of the subjects reported LBP. The most common chronotype was intermediate type (51%), followed by morningness (38%) and eveningness (11%). A significant association between eveningness and LBP was observed. After adjusting for potential confounders, individuals with eveningness had a higher prevalence of LBP than those with morningness (36.2% vs. 28.7%; odds ratio: 1.46; 95% confidence interval: 1.16-1.83).</p><p><strong>Conclusion: </strong>Eveningness was statistically associated with LBP in a cohort of public servants. The present findings would strengthen the association's generalizability to more varied populations.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144552807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A structural description for severe degeneration of intervertebral discs to computationally interpret experimental results obtained by stress profilometry. 椎间盘严重退变的结构描述,以计算解释应力轮廓术获得的实验结果。
IF 2.6 3区 医学
European Spine Journal Pub Date : 2025-07-03 DOI: 10.1007/s00586-025-09108-0
Ali Reza Nazari
{"title":"A structural description for severe degeneration of intervertebral discs to computationally interpret experimental results obtained by stress profilometry.","authors":"Ali Reza Nazari","doi":"10.1007/s00586-025-09108-0","DOIUrl":"https://doi.org/10.1007/s00586-025-09108-0","url":null,"abstract":"<p><p>In this paper, reduction of load carrying capacity in severely degenerated intervertebral discs (IVDs) was attributed to structural damage to the tissues involved with IVDs. Damage to the collagen fibers was blamed for degradation of the annulus fibrosus (AF) and dehydration of nucleus pulposus (NP) was adopted for losing its incompressibility and unstable migration in a degenerated condition. The change of the mechanical properties in the tissues due to degeneration was referred to various experimental reports that were used to simulate a computational model from a lumbar vertebral segment for a patient with degenerated IVDs. In the first phase of the study, the most accurate mechanical properties, suggested for the tissues by the various references, were selected for simulation of the stress diagrams, obtained by stress profilometry. Then in the second phase, reliability of some damage scenarios according to the pathophysiological descriptions for the tissues in a severely degenerated condition was examined. The results of the model showed that the incompressible response of NP which was taking 79% of a compression load for a normal condition of IVD, took just 40% of the load in a degenerated condition. The models postulated the residual stiffness of a severely degenerated IVD equal to 13% of its original value.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144552806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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