European Spine Journal最新文献

{"title":"Response to Letter to the Editor on \"CALM1 polymorphism in degenerative cervical myelopathy\".","authors":"Shivam Maheshwari, Vishal Kumar","doi":"10.1007/s00586-025-09205-0","DOIUrl":"10.1007/s00586-025-09205-0","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":"4794-4798"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144948473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adjacent intervertebral disc preservation or not during hemivertebra resection in the treatment of congenital scoliosis: a minimum of 5-year follow-up.","authors":"Jingwei Liu, Cheng Qiu, Jinxu Li, Zhonghua Zhou, Derun Di, Jinghang Li, Zhe Wang, Yang Li, Lianlei Wang, Yan Zhuang, Xinyu Liu","doi":"10.1007/s00586-025-08772-6","DOIUrl":"10.1007/s00586-025-08772-6","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate and compare whether removing the intervertebral disc (IVD) adjacent to the hemivertebra (HV) affects the therapeutic outcome of hemivertebra resection in pediatric patients.</p><p><strong>Methods: </strong>Pediatric patients who were diagnosed with single fully segmented or semi-segmented hemivertebra from 2011 to 2018 were included. Patients were grouped based on whether removal of IVD(s) adjacent to HV. Radiographic parameters were evaluated. Operative results were evaluated based on the correction rate after surgery and at the last follow-up. Demographic and surgical data together with perioperative complications were also analyzed.</p><p><strong>Results: </strong>Total 42 patients were included in our study, including 25 patients in the IVD preservation group (group P) and 17 patients in the IVD removal group (group R). Two groups showed similar results in terms of baseline demographics and operational data other than the estimated blood loss (EBL). The IVD preservation group presented with significantly more EBL. Both two groups showed significant postoperative scoliosis correction. However, no significant difference was found between the two groups in terms of coronal balance and radiographic parameters in the sagittal plane (segmental kyphosis, sagittal vertical axis) or overall complication rate.</p><p><strong>Conclusions: </strong>Preservation of IVD during the procedure was associated with less blood loss. However, IVD preservation procedures did not show more scoliosis recurrence or deteriorating long-term scoliosis correction outcomes. Thus, removal of HV adjacent IVD for the sake of long-term scoliosis correction outcome at the expense of increasing blood loss is doubtful and deserves further study in pediatric congenital scoliosis caused by hemivertebra.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":"4295-4306"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143735677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison of approaches to studying relationships between lumbar spinal degeneration findings demonstrates advantages to interspace-level analyses over person-level analyses.","authors":"Pradeep Suri, Elizaveta Elgaeva, Jeffrey Jarvik, Sean Rundell, Yakov Tsepilov, Frances Williams, Patrick Heagerty","doi":"10.1007/s00586-025-08976-w","DOIUrl":"10.1007/s00586-025-08976-w","url":null,"abstract":"<p><strong>Purpose: </strong>To examine associations between lumbar intervertebral disc degeneration (LDD) and type II Modic changes (MC) when retaining information at each interspace (\"interspace-level analysis\"), as compared to aggregating information across interspaces as is typically done in spine research (\"person-level analysis\"). The study compared results from (1) interspace-level analyses assuming a common relationship across interspaces (the \"interspace-level, common-relationship\" approach), (2) interspace-level analyses allowing for interspace-specific associations (an \"interspace-level, interspace-specific\" approach), (3) and a conventional person-level analytic approach.</p><p><strong>Methods: </strong>Adults in primary care (n = 147) received lumbar spine magnetic resonance imaging and neuroradiologist-evaluated assessments of prevalent disc height narrowing (DHN), type II MC, and other LDD parameters. Analyses examined associations between DHN and type II MC in interspace-level, common-relationship analyses, interspace-level, interspace-specific analyses, and conventional person-level analyses.</p><p><strong>Results: </strong>Cross-sectional, interspace-level, common-relationship analyses found large-magnitude DHN-type II MC associations (adjusted OR [aOR] = 6.5, 95% confidence intervals (CIs) 3.3-13; p < 0.001). The magnitude of this association was larger and more precise than that yielded by person-level analyses (aOR = 2.9 [95% CI 1.2-7]), and substantially more precise than interspace-level, interspace-specific analyses which allowed the association between DHN and type II MC to vary across levels. Across exploratory analyses of disc signal intensity and other MC types, interspace-level, common-relationship analyses produced larger-magnitude and more precise associations than person-level analyses in most situations, and were more precise than interspace-level, interspace-specific analyses.</p><p><strong>Conclusions: </strong>Interspace-level analytic approaches offer some advantages to person-level analyses that may be useful in understanding relationships between spinal degeneration findings.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":"4551-4557"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144257725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disc penetration sign: an distinctive MRI feature as a predictor of surgical necessity in pyogenic spondylitis.","authors":"Yutao Jiang, Shiyong Le, Jie Zhang, JiaJun Tang, Wensheng Zhang, Jie Liu, Zhuoang Lin, Shuai Tang, Liming Dong, Liang Wang","doi":"10.1007/s00586-025-09214-z","DOIUrl":"10.1007/s00586-025-09214-z","url":null,"abstract":"<p><strong>Purpose: </strong>Pyogenic spondylitis (PS) is a common spinal infection characterized by vertebral destruction and abscess formation, requiring timely intervention to mitigate irreversible neurological deficits. This study describes a novel MRI feature, termed the \"Disc Penetration sign (DP),\" defined as abscesses penetrating anteroposteriorly through the intervertebral disc space on sagittal MRI images, simultaneously compromising the anterior vertebral margins and spinal canal structures, aiming to evaluate its correlation with clinical manifestations to predict the necessity of early surgical intervention in PS patients with DP.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted, enrolling 137 patients diagnosed with pyogenic spondylitis at a tertiary hospital between 2013 and 2023. Based on MRI findings, patients were categorized into DP (n = 56) and non-DP (n = 81) groups. Two blinded clinicians independently classified the cases, with discrepancies resolved through consultation with a senior physician. Clinical indicators, laboratory parameters, imaging characteristics, microbiological profiles, and treatment modalities were analyzed. Multivariable logistic regression identified independent predictors of surgical intervention.</p><p><strong>Results: </strong>Compared to the non-DP group, the DP group exhibited significantly elevated inflammatory markers, including ESR (74.30 vs. 51.46 mm/h, p < 0.001) and CRP (47.28 vs. 26.18 mg/L, p = 0.003). Paraspinal abscesses were more prevalent in the DP group (96.4% vs. 40.7%, p < 0.001). Microbiological identification revealed a higher pathogen-positive rate in the DP group (76.8% vs. 55.6%, p = 0.011), with Staphylococcus aureus predominating in both groups. The surgical intervention rate was significantly increased in the DP group (48.2% vs. 21.0%, p < 0.001), and multivariable logistic regression confirmed DP as an independent predictor of surgical necessity (adjusted OR = 2.47, 95% CI: 1.21-5.07, p = 0.032).</p><p><strong>Conclusion: </strong>The Disc Penetration sign (DP) is a distinct MRI feature strongly associated with severe inflammatory burden, higher pathogen detection rates, and increased necessity for surgical intervention in pyogenic spondylitis.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":"4661-4669"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144774959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Answer to the letter to the editor of E. Gurun concerning \"Quadratus lumborum muscle stiffness in chronic non-specific low back pain: a diagnostic accuracy study\" by M. López-Redondo, et al. (Eur spine J [2025]; doi: 10.1007/s00586-025-09114-2).","authors":"Juan Antonio Valera-Calero","doi":"10.1007/s00586-025-09229-6","DOIUrl":"10.1007/s00586-025-09229-6","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":"4818"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144811992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Are combined conservative interventions effective in reducing pain, disability and/or global rating of pain in people with sciatica with known neuropathic pain mechanisms?","authors":"Colette Ridehalgh, Shemane Murtagh, Kika Konstantinou, Andrew Dilley","doi":"10.1007/s00586-025-09233-w","DOIUrl":"10.1007/s00586-025-09233-w","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":"4870"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Surgical strategies and outcomes in degenerative myelopathy at the cervico-thoracic junction: a multicenter retrospective analysis.","authors":"Giuseppe Emmanuele Umana, Gianluca Scalia, Luca Ricciardi, Giorgio Lofrese, Lorenzo Mongardi, Nicola Montemurro, Francesco Acerbi, Lidia Strigari, Miguel Ruiz Cardozo, Gabriele Capo, Ali Baram, Maurizio Fornari, Camilo Molina","doi":"10.1007/s00586-025-09230-z","DOIUrl":"10.1007/s00586-025-09230-z","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":"4867-4868"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor concerning \"ALIF vs. posterior fusion for lumbar degenerative disease: comparable efficacy but elevated risk of severe complications-a systematic review and meta-analysis\" by FJ Onishi, et al. (Eur spine J [2025]; doi: 10.1007/s00586-025-08914-w).","authors":"Aécio Rubens Dias Pereira Filho, Francisco Cialdine Frota Carneiro Júnior, Vinicius de Meldau Benites","doi":"10.1007/s00586-025-09265-2","DOIUrl":"10.1007/s00586-025-09265-2","url":null,"abstract":"","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":"4833-4834"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144948287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolution of pelvic incidence and lumbar lordosis during growth: MRI-based evaluation from fetal stage to early childhood.","authors":"Hassan Najdi, Corentin Petitpas, Ahmed-Ali El Ahmadi, Elie Choufani, Franck Launay, Jean-Luc Jouve, Solene Prost, Benjamin Blondel, Pascal Adalian, Kathia Chaumoitre, Sébastien Pesenti","doi":"10.1007/s00586-025-08920-y","DOIUrl":"10.1007/s00586-025-08920-y","url":null,"abstract":"<p><strong>Purpose: </strong>Upstanding posture depends on the balance between the pelvis and spine, with minimal energy expenditure when spinal segments are aligned. Pelvic incidence (PI), a key measure of sagittal balance, is a constant individual characteristic that correlates with lumbar lordosis (LL) in adults. While sagittal balance has been widely studied in adults, there is limited research on the pediatric population, particularly pre-walking children and fetuses.</p><p><strong>Methods: </strong>This study aimed to describe the development of PI and LL in healthy fetuses and children under 10 years old using MRI measurements. A retrospective analysis of MRI images from 96 subjects (20 fetuses and 76 children) undergoing MRI for non-spinal conditions was conducted. PI, wedging lumbar vertebral body angles (WVB) of L1-L5, and the sum of all WVB angles (SLL) were measured to assess their development and correlation with age.</p><p><strong>Results: </strong>Results showed a slight positive correlation between PI and age, with a significant increase occurring during the acquisition of bipedalism. LL also increased with age, with notable postnatal development continuing into early childhood. Structural lordosis in the L4 and L5 vertebrae was evident in fetuses, indicating the presence of inherent lordosis in utero.</p><p><strong>Conclusion: </strong>While PI exhibited minor changes after birth, LL development was strongly influenced by biomechanical factors associated with growth and bipedalism. These findings improve our understanding of the evolution of spino-pelvic anatomy and could guide therapeutic approaches for pediatric spinal deformities. Further longitudinal studies are needed to explore the genetic and biomechanical determinants of PI and LL development.</p>","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":"4275-4284"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with immediate post-operative complications in pediatric patients in intensive care after spinal deformity surgical repair.","authors":"Reut Kassif Lerner, Amiad Levi Baltzan, Nissim Ackshota, Evyatar Hubara, Tal Sadeh, Marina Rubinstein, Gidi Paret, Itai M Pessach","doi":"10.1007/s00586-025-08974-y","DOIUrl":"10.1007/s00586-025-08974-y","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Surgical repair is a widely used and effective treatment for pediatric scoliosis, significantly improving patients' quality of life. However, despite the overall safety of these procedures, postoperative complications can occur, presenting notable challenges. To ensure optimal monitoring and management, pediatric scoliosis patients are frequently admitted to the pediatric intensive care unit (PICU) during the immediate postoperative period. This study aimed to identify patient characteristics associated with immediate postoperative complications within the first 48 h following spinal deformity surgery. Furthermore, it sought to evaluate the types, prevalence, and severity of these complications, as well as the risk factors contributing to their development.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A retrospective cohort study was conducted, encompassing all children aged 8 to 18 years who underwent spinal deformity surgery and were admitted to the largest tertiary pediatric intensive care unit (PICU) in Israel between 2010 and 2021. Clinical and laboratory data were extracted from electronic medical records and systematically analyzed. Statistical analyses were performed to identify risk factors associated with immediate postoperative complications occurring within the first 48 h after surgery.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The study included 81 pediatric patients who underwent spinal deformity surgery. Of these, 41 (50%) experienced complications within the first 48 h post-surgery. Patients with comorbidities demonstrated a higher prevalence of complications (RR = 1.8; 95% CI = 1.12-2.91). A significantly increased risk of hemodynamic complications was observed in patients with serum lactate levels above 2 mmol/L upon PICU admission (RR = 7.3; 95% CI = 2.45-21.79) and in those with a significant decrease in hemoglobin levels (RR = 4.56; 95% CI = 1.76-11.83). Additionally, patients with CRP levels above 20 mg/dL or albumin levels below 3 mg/dL upon admission had significantly higher relative risks of general complications (RR = 1.71; 95% CI = 1.12-2.63 and RR = 1.57; 95% CI = 1.06-2.32, respectively). A predictive model for significant complications in pediatric patients following spinal deformity surgery was developed based on these factors. The model was able to predict possible immediate complications with an AUC of 0.74 and with scores above 4 points demonstrated 100% specificity and 100% positive predictive value in identifying complications at the time of PICU admission. Using this model, we effectively stratified patients into low-risk and high-risk groups for postoperative complications.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;We identified several factors associated with an increased risk of complications within 48 h following pediatric spinal deformity surgery. A simple and easy to use predictive model developed using these factors demonstrated good performance allowing stratification of patients upon admission to th","PeriodicalId":12323,"journal":{"name":"European Spine Journal","volume":" ","pages":"4314-4322"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}