Ibrahim Shirehan M, Ibrahim Elamin M, Ibrahim Omer A, A. Enas, Hamid Omnia M, Alaziz Hassan A
{"title":"Molecular Diagnosis and Identification of Carbapenemase Producing Acinetobacter baumannii among ICU Patients, in Khartoum State-Sudan","authors":"Ibrahim Shirehan M, Ibrahim Elamin M, Ibrahim Omer A, A. Enas, Hamid Omnia M, Alaziz Hassan A","doi":"10.36959/958/586","DOIUrl":"https://doi.org/10.36959/958/586","url":null,"abstract":"","PeriodicalId":122812,"journal":{"name":"Annals of Microbiology and Research","volume":"53 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114041548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rise of the Phoenix: Mucormycosis in the Context of COVID-19","authors":"Dias Vanessa Cordeiro","doi":"10.36959/958/584","DOIUrl":"https://doi.org/10.36959/958/584","url":null,"abstract":"Opportunistic infections are especially common in patients who, apart from the current COVID-19 disease, also have other comorbidities such as diabetes, prolonged stay in intensive care unit, treatment with mechanical ventilation, antibiotic therapy and prolonged use of corticosteroids. Mucormycosis, for example, is an acute or sub acute rapidly progressing infections caused by the angioinvasive fungi in the order of Mucorales such as species of Rhizopus, Mucor, Rhizomucor, Syncephalastrum, Cunninghamella, Apophysomyces and Lichtheimia. This infection is characterized by vascular invasion by the fungal hyphae which leads to thrombosis and necrosis. To diagnose the suspicion of mucormycosis, an extensive analysis of the patient's history associated with physical and imaging examination is very important. Biopsy, culture in specific media and polymerase chain reaction (PCR) of clinical specimens can be used to identify the fungus agent of mucormycosis. The widely accepted treatment of choice for mucormycosisis amphotericin B. In addition to early detection of the fungus, the correction of pre-existing pathologies (such as diabetes, immunosuppression and inflammation) is of great importance to ensure therapeutic success. Thus, given this scenario, it is imperative that clinicians should be sensitized to the increased risk of development of this fatal infection, especially while treating diabetic patients with COVID-19, using corticosteroids.","PeriodicalId":122812,"journal":{"name":"Annals of Microbiology and Research","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132595237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Naviaux Anne-Frédérique, J. Pascal, Maximilien Gourdin Maximilien Gourdin
{"title":"COVID-19, Vaccination and Healthy Living: Protecting Yourself or Exposing Others? The Kiss that Kills","authors":"Naviaux Anne-Frédérique, J. Pascal, Maximilien Gourdin Maximilien Gourdin","doi":"10.36959/958/582","DOIUrl":"https://doi.org/10.36959/958/582","url":null,"abstract":"At a time when vaccines are spreading, there are still pockets of resistance, mainly of a social, psychological and behavioral nature, but also of an economic and health nature in developing countries. We focus here on the social, psychological and behavioral aspects of this resistance. The struggle against Covid-19 is becoming less and less immunological and more and more intrapsychic and social. It is therefore these parameters that need to be targeted. To this end, media campaigns to promote health, but above all to reduce resistance, are therefore quite essential and take precedence over hygiene measures, which citizens are completely saturated with.","PeriodicalId":122812,"journal":{"name":"Annals of Microbiology and Research","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126185271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lau Chin Shern, Phua Soon Kieng, Liang Ya Li, OH May Lin Helen, AW Tar-Choon
{"title":"Early Pfizer Covid-19 Vaccine Elicited Spike Antibody (total, IgG, IgM) Responses Compared to Chemiluminescent Neutralizing Antibodies","authors":"Lau Chin Shern, Phua Soon Kieng, Liang Ya Li, OH May Lin Helen, AW Tar-Choon","doi":"10.36959/958/581","DOIUrl":"https://doi.org/10.36959/958/581","url":null,"abstract":"Responses Compared to Chemiluminescent Neutralizing Antibodies. Abstract Introduction: We compared the total, IgG and IgM spike antibodies (S-Ab) to neutralizing antibody (N-Ab) responses in seronegative subjects after the first and second doses of the BNT162b2 mRNA COVID-19 vaccine. Methods: sixty-five volunteers were tested pre-vaccination, 10 days after the first dose of vaccine, and 20 days after dose two (17 males, 48 females, mean age 41.5 ± 14.1-years). Total/IgG/IgM were assessed with Roche and Abbott immunoassays, with N-Ab using the Snibe Maglumi SARS-CoV-2 immunoassay. Results: Ten days after first vaccination, 64.6% (n = 42) and 66.2% (n = 43) were S-Ab (total and IgG) positive; however, only 13.8% (n = 9) and 10.8% (n = 7) were IgM and N-Ab positive. Younger patients (< 50-years-old) had significantly higher S-Ab responses after the first vaccine dose (difference between age groups: total 1.12 BAU/mL, 95% CI 0-3.69, p = 0.02; IgG 11.4 BAU/mL, 95% CI 2.72-37.1, p = 0.01; IgM COI 0.24, 95% CI 0.05-0.52, p = 0.01). 20 days after second vaccination, ALL participants had high antibodies - IgG (265-7764 BAU/mL), total (274-6127 BAU/mL) and N-Ab (0.51-15.7 ug/mL). In total, females displayed greater IgG (52.5 BAU/mL, 95% CI 2.47-912, p = 0.02) and N-Ab (0.1 ug/mL, 95% CI 0.01-1.26, p = 0.03) responses than males. Total and IgG displayed better correlation with N-Ab after vaccination than IgM (total and IgG Pearson correlation coefficient both r = 0.96, IgM r = 0.78). Conclusion: In seronegative subjects, S-Ab or N-Ab may not be reactive 10 days after a single dose of vaccine, especially males ≥ 50-years-old. However, all subjects had high total, IgG and N-Ab positive 20 days after 2 vaccinations.","PeriodicalId":122812,"journal":{"name":"Annals of Microbiology and Research","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115642848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Retrospective Study of Uropathogenic ESBL-producing Enterobacteriaceae among Hospitalized Patients, Khartoum-Sudan","authors":"M. HamidOmnia, A. BayoumiMagdi","doi":"10.36959/958/580","DOIUrl":"https://doi.org/10.36959/958/580","url":null,"abstract":"Uropathogenic extended-spectrum beta-lactamases-producing Enterobacteriaceae (ESBL-PE) remains a global cause of urinary tract infections (UTIs) among hospitalized patients as these enzymes hydrolysing 3rd generation cephalosporin's (3rd GC). Those bacteria may not respond to therapy and thus further limiting antimicrobial selections. This study aimed to detect uropathogenic Enterobacteriaceae producing ESBL genes and their antimicrobial resistance pattern.","PeriodicalId":122812,"journal":{"name":"Annals of Microbiology and Research","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114390038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phase 3 for COVID-19 in Italy: From a Retrospective Analysis on Deaths among Doctors in Hospitals to the Return of Children at School","authors":"Ranalli Giancarlo, Fabio Divino, Ranalli Marco, Ripabelli Giancarlo","doi":"10.36959/958/579","DOIUrl":"https://doi.org/10.36959/958/579","url":null,"abstract":"The cause of Coronavirus disease 2019 (COVID-19) is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is sadly well known for the dramatic loss of life it has led to; this new disease was declared a pandemic by the WHO on March 11, 2020. After the People’s Republic of China, a large part of Northern Italy (the Lombardy and Veneto Regions) was the first area in Europe to be seriously affected by COVID-19, inducing the regional and central Governments to take a number of social-distancing measures to reduce the spread of the virus by adopting phase 1 of the lockdown. The pandemic has caused tens of thousands of deaths not only in the older population, but also among the doctors and health workers involved in the fight against the virus. An overview of past epidemic diffusion in Italy is reported, underlining the potential factors that could have contributed to such a large number of deaths among doctors (total 176) today, at Tzero for phase 3, September 14, 2020 with the Return of Children at school. Moreover, we make some proposals and suggestions to improve prevention for any up-surge in COVID-19, like the improve of bacterial filtration efficiency for materials designated in the production of medical-standard face-masks.","PeriodicalId":122812,"journal":{"name":"Annals of Microbiology and Research","volume":"02 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131202183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Naviaux Anne-Frédérique, J. Pascal, Gourdin Maximilien
{"title":"To be (Masked) or Not to be (Masked) during the Covid-19 Pandemic: A Social and Psychological Double Bind","authors":"Naviaux Anne-Frédérique, J. Pascal, Gourdin Maximilien","doi":"10.36959/958/578","DOIUrl":"https://doi.org/10.36959/958/578","url":null,"abstract":"In the context of the exponential growth of the pandemic, everyone has to make some decision: When there is a world shortage of material (screening tests, masks, respirators and vaccine), societal measures are crucial to contain an epidemic. In this context, psychological and behavioral parameters become directly relevant to public health, but can also subject us to a philosophical argument as in Pascal’s wager. To be masked or not to be masked during the Covid-19 Pandemic appears then as a social and psychological double bind.","PeriodicalId":122812,"journal":{"name":"Annals of Microbiology and Research","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126035265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Saleem, B. Deters, Adam de la Bastide, Martha Korzen
{"title":"Antibiotics Overuse and Bacterial Resistance","authors":"M. Saleem, B. Deters, Adam de la Bastide, Martha Korzen","doi":"10.36959/958/573","DOIUrl":"https://doi.org/10.36959/958/573","url":null,"abstract":"Antibiotic usage has become very widespread, as they are used to treat so many infectious diseases today. Antimicrobial agents exert their actions via different mechanisms including blockage of cell wall synthesis, interference of protein and/or nucleic acid synthesis, interruption of cell membrane structure, and inhibition of a metabolic pathway.","PeriodicalId":122812,"journal":{"name":"Annals of Microbiology and Research","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125278969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Extended Spectrum Beta-Lactamase Producing Enterobacteriaceae: Hospital-Acquired Urinary Tract Infections, Khartoum","authors":"P. Somasundaran, H. Shimaa, P. Patra, S. H. El","doi":"10.36959/958/572","DOIUrl":"https://doi.org/10.36959/958/572","url":null,"abstract":"A descriptive; cross-sectional study was conducted on 350 Clean-catch, mid-stream urine samples (MSU) from both gender (female and male) patients hospitalized in Academic Charity Teaching Hospital with sign and symptom of UTI. The gram-negative isolates were identified and screened by Kirby-Bauer disc diffusion method. Double-Disc Synergy Test (DDST) was performed for detection and confirmation of ESBLs. Socio-demographic and clinical data were obtained from each participant using close-end questionnaires with palace to sign or stamp (a way to protect patients confidentiality) and check list for practical follow-up work and record.","PeriodicalId":122812,"journal":{"name":"Annals of Microbiology and Research","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123606638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative Study of Biodegradation and Coagulation of Dairy Effluent by Using Immobilized Microbial Isolates and Chitosane Silver Nano Particles and Production Biodiesel","authors":"M. Moustafa","doi":"10.36959/958/571","DOIUrl":"https://doi.org/10.36959/958/571","url":null,"abstract":"Environmental pollution is one of the major ecological difficulties, rapid growth of industrial and explosion of population are the primary reasons for the dwindling water quality. In last few decades, requiring urgent attention has been paid to the industrial wastes, which are usually discharged harmful and toxic substances into on land or into different natural water sources such as rivers and canals and creating health hazards.","PeriodicalId":122812,"journal":{"name":"Annals of Microbiology and Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127094169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}