Evidence-based Complementary and Alternative Medicine最新文献

{"title":"RETRACTION: Korean Red Ginseng Suppresses Metastasis of Human Hepatoma SK-Hep1 Cells by Inhibiting Matrix Metalloproteinase-2/-9 and Urokinase Plasminogen Activator.","authors":"Evidence-Based Complementary And Alternative Medicine","doi":"10.1155/ecam/9839547","DOIUrl":"https://doi.org/10.1155/ecam/9839547","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2012/965846.].</p>","PeriodicalId":12236,"journal":{"name":"Evidence-based Complementary and Alternative Medicine","volume":"2025 ","pages":"9839547"},"PeriodicalIF":0.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12119153/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION: \"Effectiveness and Safety of the Korean Medicine Senior Health Promotion Program Using Herbal Medicine and Acupuncture for Mild Cognitive Impairment: A Retrospective Study of 500 Patients in Seoul, Korea\".","authors":"Evidence-Based Complementary And Alternative Medicine","doi":"10.1155/ecam/9816427","DOIUrl":"https://doi.org/10.1155/ecam/9816427","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2021/8820705.].</p>","PeriodicalId":12236,"journal":{"name":"Evidence-based Complementary and Alternative Medicine","volume":"2025 ","pages":"9816427"},"PeriodicalIF":0.0,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION: \"The Proliferation Enhancing Effects of Salidroside on Schwann Cells In Vitro\".","authors":"Evidence-Based Complementary And Alternative Medicine","doi":"10.1155/ecam/9857212","DOIUrl":"https://doi.org/10.1155/ecam/9857212","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2017/4673289.].</p>","PeriodicalId":12236,"journal":{"name":"Evidence-based Complementary and Alternative Medicine","volume":"2025 ","pages":"9857212"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION: <i>Ex Vivo</i> Stromal Cell-Derived Factor 1-Mediated Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells into Hepatocytes Is Enhanced by Chinese Medicine Yiguanjian Drug-Containing Serum.","authors":"Evidence-Based Complementary And Alternative Medicine","doi":"10.1155/ecam/9812485","DOIUrl":"10.1155/ecam/9812485","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2016/7380439.].</p>","PeriodicalId":12236,"journal":{"name":"Evidence-based Complementary and Alternative Medicine","volume":"2025 ","pages":"9812485"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to Exploring the Mechanism of Berberine Intervention in Ulcerative Colitis From the Perspective of Inflammation and Immunity Based on Systemic Pharmacology.","authors":"Yan Jiang, Li Zhao, Qing Chen, Lihong Zhou","doi":"10.1155/ecam/9803142","DOIUrl":"https://doi.org/10.1155/ecam/9803142","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1155/2021/9970240.].</p>","PeriodicalId":12236,"journal":{"name":"Evidence-based Complementary and Alternative Medicine","volume":"2025 ","pages":"9803142"},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"PEI-PEG-Coated Mesoporous Silica Nanoparticles Enhance the Antitumor Activity of Tanshinone IIA and Serve as a Gene Transfer Vector\".","authors":"Yinxing Zhu, Miao Yue, Ting Guo, Fang Li, Zhifeng Li, Dazhuang Yang, Mei Lin","doi":"10.1155/ecam/9763501","DOIUrl":"10.1155/ecam/9763501","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1155/2021/6756763.].</p>","PeriodicalId":12236,"journal":{"name":"Evidence-based Complementary and Alternative Medicine","volume":"2025 ","pages":"9763501"},"PeriodicalIF":0.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retracted: Antiulcerogenic Activity of Li-Zhong Decoction on Duodenal Ulcers Induced by Indomethacin in Rats: Involvement of TLR-2/MyD88 Signaling Pathway.","authors":"Evidence-Based Complementary And Alternative Medicine","doi":"10.1155/2024/9831531","DOIUrl":"10.1155/2024/9831531","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2020/6538156.].</p>","PeriodicalId":12236,"journal":{"name":"Evidence-based Complementary and Alternative Medicine","volume":"2024 ","pages":"9831531"},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11293942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141874562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of In Vivo Antidiarrheal Activities of 80% Methanol Extract and Solvent Fractions of Peels of <i>Colocasia esculenta</i> (Araceae).","authors":"Temesgen Obsa Terfa, Fekadu Abera Kebede, Monas Kitessa Beyene, Tilahun Tesfaye Abebe, Abebe Basazn Mekuria, Jibril Seid Yesuf","doi":"10.1155/2024/2728282","DOIUrl":"10.1155/2024/2728282","url":null,"abstract":"<p><strong>Background: </strong>Diarrhea is the common gastrointestinal disorder accounting for 2.5 billion episodes and 1.5 million deaths annually. Limitations and inaccessibility of currently available medications are the main problem associated with treatment of diarrhea. Hence, medicinal plants are usually preferred to manage diarrhea because they may contain constituents with high activity and fewer side effects. Even though the dose, safety, and efficacy of <i>Colocasia esculenta</i> (L.) Schott are not substantiated scientifically, several societies use it for the treatment of diarrhea.</p><p><strong>Objective: </strong>This study was targeted at exploring the in vivo antidiarrheal activities of 80% methanol extract and solvent fractions of peels of <i>Colocasia esculenta</i> (L.) Schott in Swiss albino mice.</p><p><strong>Methods: </strong>The plant was collected and extracted with 80% methanol, followed by fractionation with distilled water, chloroform, and diethyl ether. Castor oil-induced diarrhea, enteropooling, and motility tests were used to evaluate antidiarrheal activity. The test groups received graded doses of 100 mg/kg, 200 mg/kg, and 400 mg/kg. Negative controls received 10 ml/kg of 2% Tween 80 while positive controls received loperamide (3 mg/kg) or atropine (5 mg/kg).</p><p><strong>Results: </strong>The crude and solvent fractions of the plant extract have induced significant effects in reduction of the number and weight of wet stools at all tested doses. However, delay in onset of diarrhea was observed only at 400 mg/kg (<i>P</i> < 0.001) for both crude extract and solvent fractions. In antienteropooling test, 80% methanol extract and solvent fractions have significantly reduced the weight and volume of intestinal contents, especially at 200 mg/kg and 400 mg/kg. Regarding the antimotility test, the crude extract reduced motility at all tested doses, whereas the solvent fractions reduced intestinal motility mainly at 400 mg/kg (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>The study has revealed that the 80% methanol extract and solvent fractions of the plant possess antidiarrheal activities supporting the traditional antidiarrheal claims of the plant.</p>","PeriodicalId":12236,"journal":{"name":"Evidence-based Complementary and Alternative Medicine","volume":"2024 ","pages":"2728282"},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-<i>Helicobacter pylori</i> Effects of <i>Thymus caramanicus</i> Jalas Essential Oils: A New Antimicrobial Approach.","authors":"Sepehr Asadi, Ebrahim Rahimi, Amir Shakerian","doi":"10.1155/2024/3627074","DOIUrl":"10.1155/2024/3627074","url":null,"abstract":"<p><strong>Background: </strong><i>Helicobacter pylori</i> are the principal causative factor in the etiological factors of chronic, active, or type B gastritis; peptic and duodenal ulcers; stomach carcinoma; and epithelial tissue lymphoid malignancies. It infects more than half of the population worldwide. To reduce <i>H. pylori</i> production, pharmacological therapy of <i>H. pylori</i> diseases typically involves using threefold treatment methods. However, as a result of such therapy, antimicrobial resistance is commonly developed. Alternative therapeutics for <i>H. pylori</i> diseases are thus of particular interest.</p><p><strong>Methods: </strong>Thyme essential oils (EOs) obtained from <i>T. caramanicus</i> Jalas plants in Iran were tested for antibacterial activity against <i>H. pylori</i> obtained from 320 poultry specimens in this investigation. Antibacterial activity was measured using inhibition zones, minimum inhibitory concentrations (MICs), and minimum bactericidal concentrations (MBCs). The impact of <i>T. caramanicus</i> Jalas essential oils on <i>H. pylori</i> isolate <i>cagA</i>, <i>vacA</i>, and <i>babA2</i> gene expression was evaluated using a quantitative real-time PCR method (<i>p</i> < 0.05).</p><p><strong>Results: </strong>The chemical content of these EOs varied significantly according to chromatographic examination. Thymol, carvacrol, and terpinene-4-ol are the most abundant components in these EOs. <i>H. pylori</i> was recognized as a <i>Helicobacter</i> species with a 175-bp PCR product of 16S rRNA in 20/20 (100%). According to PCR results, all 20 (100%) isolates belonged to <i>H. pylori</i>. The EOs inhibited <i>H. pylori</i> in a dose-dependent manner, with <i>T. caramanicus</i> Jalas being the most effective, followed by pterygium EOs in decreasing order. At 8 mg/mL of <i>T. caramanicus</i> Jalas EOs, IZs against <i>H. pylori</i> were 27.4 ± 0.42 mm, and at 8 mg/mL of pterygium, IZs against <i>H. pylori</i> were 1 ± 0.02. <i>T. caramanicus</i> Jalas essential oils were used to treat all bacteria, and the findings showed that <i>T. caramanicus</i> Jalas had a substantial inhibitory impact on the expression of <i>cagA</i>, <i>vacA</i>, and <i>babA2</i> virulence-related genes (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>In a dose-dependent manner, the EOs of <i>T. caramanicus</i> Jalas EO demonstrated a high degree of antimicrobial property against <i>H. pylori</i> bacteria. The most efficient EOs were those from <i>T. caramanicus</i> Jalas with relative concentrations of thymol and carvacrol, followed by the coumarin-dominated pterygium EO with reduced antibacterial activity.</p>","PeriodicalId":12236,"journal":{"name":"Evidence-based Complementary and Alternative Medicine","volume":"2024 ","pages":"3627074"},"PeriodicalIF":0.0,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11182686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141418501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibacterial and Antioxidant Compounds from the Root Extract of <i>Aloe debrana</i>.","authors":"Tokuma Getahun, Joydeep Das, Parames C Sil, Neeraj Gupta","doi":"10.1155/2024/6651648","DOIUrl":"10.1155/2024/6651648","url":null,"abstract":"<p><p>This study was conducted to isolate and identify the chemical compounds from the roots of <i>Aloe debrana</i> (L.) and evaluate their antioxidant and antibacterial activities. From the acetone (99.5%) extract of the roots of this plant, four anthraquinones, such as chrysophanol (<b>1</b>), asphodeline (<b>2</b>), aloesaponarin I (<b>5</b>), and laccaic acid D-methyl ester (<b>6</b>), and a new catechol derivative, 5-allyl-3-methoxybenzene-1,2-diol (<b>3</b>), were isolated and elucidated by different chromatographic and spectroscopic methods together with linoleic acid (<b>4</b>), respectively. Compounds <b>2</b>, <b>3,</b> and <b>4</b> were reported here for the first time from this plant and compound <b>3</b> from the genus <i>Aloe</i>. The compounds were evaluated for their antioxidant activity using H₂O₂ and DPPH assays and bactericidal activity against <i>S. aureus</i> and <i>E. coli</i>. Compounds <b>3</b> and <b>6</b> showed highest antioxidant activities with IC₅₀ values of 19.38 ± 0.64 and 32.81 ± 0.78 <i>μ</i>g/mL in DPPH, and 28.52 ± 1.08 and 27.31 ± 1.46 <i>μ</i>g/mL in H₂O₂, respectively. The isolated compounds also demonstrated considerable activity towards <i>S. aureus</i>. Among these compounds, compound <b>3</b> exhibited the highest activity (91.20 ± 0.12% and 9.14 ± 0.93 mm at 1.0 mg/mL) against this bacterium. The overall results suggest that the isolated compounds may be considered as potential sources of the bioactive agents to be used in the pharmacological, food, and other industries. Moreover, their high sensitivity against <i>S. aureus</i> may also support the use of <i>A. debrana</i> plant in the traditional medicine to treat wounds. Therefore, the isolated compounds are responsible for medicinal properties of this plant.</p>","PeriodicalId":12236,"journal":{"name":"Evidence-based Complementary and Alternative Medicine","volume":"2024 ","pages":"6651648"},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11093683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140921861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}