{"title":"Management strategies for posterior deciduous and permanent teeth with developmental defects of enamel presenting post-eruptive breakdown or atypical cavitated carious lesions: systematic review and meta-analysis.","authors":"Aline Maquiné Pascareli-Carlos, Rayane Melo Ribeiro, Beatriz Tebalde Albuquerque Souza, Isabela Floriano, Michele Baffi Diniz, Sávio José Cardoso Bezerra, Erika Meneses Silva, Daniela Prócida Raggio, Tatiane Fernandes Novaes, Tamara Kerber Tedesco","doi":"10.1038/s41432-025-01167-y","DOIUrl":"https://doi.org/10.1038/s41432-025-01167-y","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate different management strategies for treating posterior deciduous and permanent teeth affected by developmental defects of enamel (DDE) presenting with post-eruptive breakdown or atypical cavitated carious lesions, with a focus on longevity and the acceptability/perception of the treatment by parents and children.</p><p><strong>Methods: </strong>A comprehensive search of electronic databases was conducted up to April 09, 2025, to identify clinical studies addressing treatment approaches for posterior deciduous or permanent teeth with DDE in children up to 14 years old.</p><p><strong>Results: </strong>Ninety studies met the inclusion criteria: 15 focused on molar-incisor hypomineralisation (MIH), one on hypomineralised second primary molar, one on amelogenesis imperfecta, and two covering various types of DDE. The most used restorative treatments included aesthetic and metal crowns, composite resin (CR) and glass ionomer cement (GIC) restorations, and indirect restoration with composite resin (ICR) and ceramics (ICeramics), which have been well accepted by both parents and children. Meta-analyses were conducted exclusively on studies related to MIH. Over a 24-month follow-up period, the overall success rate was 84% (95% CI: 70-99%). Subgroup analyses did not indicate significant differences among restorative treatment options (p = 0.336).</p><p><strong>Conclusion: </strong>Aesthetic and metal crowns, ICR, ICeramics, CR, and GIC may be viable treatment options for the management of MIH and other types of DDE. However, the certainty of the evidence remains low, and most studies exhibited a high or critical risk of bias.</p>","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Harry Tiernan, Muhammad Masud, Sawyer Lange, Shanika Nanayakkara, Thilini N Jayasinghe
{"title":"The association between maternal smoking during pregnancy and dental development in offspring: a systematic review.","authors":"Harry Tiernan, Muhammad Masud, Sawyer Lange, Shanika Nanayakkara, Thilini N Jayasinghe","doi":"10.1038/s41432-025-01168-x","DOIUrl":"https://doi.org/10.1038/s41432-025-01168-x","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the effect of maternal smoking during pregnancy (MSDP) on the development of dental conditions in human offspring, as presented in current literature.</p><p><strong>Methods: </strong>Observational studies from six databases (MEDLINE, Embase, CINAHL, Scopus, Web of Science and Maternity and Infant Care (MIC)) were systematically searched in July 2024. Articles were screened based on their investigation of the effect of MSDP on the development of dental conditions in offspring. Methodological quality was assessed using the Newcastle Ottawa Scale (NOS), while the quality of evidence was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) approach.</p><p><strong>Results: </strong>A total of 17 articles were included in this review, focusing on the primary dental developmental outcomes: molar incisor hypomineralisation (MIH), enamel defects (other than MIH), missing teeth, dental eruption, and short root anomaly. Due to high levels of heterogeneity among the studies, meta-analysis was not performed. The majority of studies demonstrated good methodological quality (n = 10), with three assessed as fair and four as poor. The quality of evidence was categorised, with three outcomes receiving a low quality of evidence classification, and tooth eruption and short root anomaly being classed as very low quality. Statistically significant associations between MSDP and each dental outcome had varied results across studies. Most studies concluded an association between MSDP and conditions such as enamel defects (other than MIH), missing teeth, and short root anomaly. Some studies found associations with MIH, while the majority found no link between MSDP and tooth eruption in offspring.</p><p><strong>Conclusion: </strong>This review suggests a potential association between MSDP and dental development conditions in offspring. However, due to the low quality of evidence and inconsistencies in findings across observational studies, a definitive association cannot be drawn. Further, novel and high-quality research is needed to understand the impact MSDP on dental development in offspring.</p>","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jonathan Rafael Garbim, Livia da Rosa Oliveira, Rodolfo de Carvalho Oliveira, Tamara Kerber Tedesco, Daniela Prócida Raggio
{"title":"Which management strategy has the highest success rate for occlusoproximal caries lesions in primary molars? A systematic review and network meta-analysis.","authors":"Jonathan Rafael Garbim, Livia da Rosa Oliveira, Rodolfo de Carvalho Oliveira, Tamara Kerber Tedesco, Daniela Prócida Raggio","doi":"10.1038/s41432-025-01164-1","DOIUrl":"https://doi.org/10.1038/s41432-025-01164-1","url":null,"abstract":"<p><strong>Aim: </strong>Managing occlusoproximal lesions remains a challenge for dental professionals. The aim of this systematic review was to identify the best strategy to treat occlusoproximal caries lesions in primary molars.</p><p><strong>Methods: </strong>A systematic search was conducted in MEDLINE/PubMed, Web of Science, Scopus, EMBASE, and ProQuest up to 7th February 2024. Randomized controlled trials comparing different management strategies for occlusoproximal caries lesions with at least 12 months of follow-up were included. Network meta-analyses were carried out considering the success rate of the treatments as the outcome. Risk of bias was assessed using the RoB 2 tool, and the certainty of evidence with the GRADE tool.</p><p><strong>Results: </strong>Seven studies were included, evaluating five treatment modalities: Hall Technique (HT), non-restorative cavity control (NRCC), conventional restorative treatment (CRT), silver diamine fluoride application (SDF), and Atraumatic Restorative Treatment (ART). HT had the highest success rate (80.8%). There was no statistical difference between other strategies. Only two studies showed a low risk of bias; the others had a high risk, primarily due to selective reporting bias.</p><p><strong>Discussion: </strong>The HT had the highest success rate at 80.8%, making it the most effective treatment for occlusoproximal caries in primary molars. However, no significant difference was found between other treatment strategies. The certainty of evidence is limited by the high risk of bias, particularly selective reporting bias. Future research should also consider factors like patient preference and cost-effectiveness to better assess treatments in a patient-centered context.</p><p><strong>Conclusion: </strong>HT is the most effective option for managing occlusoproximal caries in primary molars in terms of success rate. However, the evidence is based on studies with a high risk of bias, and the certainty of evidence ranges from very low to moderate.</p><p><strong>Prospero: </strong>CRD42021281085.</p>","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dentures and the oral microbiome: Unraveling the hidden impact on edentulous and partially edentulous patients - a systematic review and meta-analysis.","authors":"Seenivasan Madhan Kumar, Shanmuganathan Natarajan, Sridharan Ks, Senthil Kumar Sundarajan, Parthasarathy Natarajan, A Selva Arockiam","doi":"10.1038/s41432-025-01149-0","DOIUrl":"https://doi.org/10.1038/s41432-025-01149-0","url":null,"abstract":"<p><strong>Objective: </strong>This systematic review and meta-analysis evaluate the impact of edentulism and denture use on the oral microbiome, focusing on microbial diversity, colonization and biofilm formation in completely and partially edentulous patients.</p><p><strong>Methods: </strong>A comprehensive search was conducted across five databases (PubMed-Medline, Scopus, Embase, Lilacs, and Google Scholar) until June 1, 2024. Randomized and non-randomized clinical trials, observational studies, and cohort studies were included. Data extraction and risk of bias assessment followed PRISMA guidelines. Meta-analysis was performed using STATA and R software with a random effects maximum likelihood model. Microbial co-occurrence networks, heatmaps, and longitudinal trends were analyzed, with heterogeneity assessed using Higgin's I² (substantial heterogeneity defined as I² > 50%).</p><p><strong>Results: </strong>Thirty-two studies met the inclusion criteria. The oral microbiome in edentulous patients differed significantly from dentate individuals, influenced by denture materials, design, and time. Veillonella abundance in acrylic complete dentures was 13.63% (95% CI = -0.04, 27.29), I² = 90.98%, compared to 49.10% (95% CI = -29.62, 115.81), I² = 99.47% in dentate patients. Candida albicans increased over time in acrylic dentures, from 63.13% (95% CI = 48.93, 77.33), I² = 99.84% after insertion to 344.72 CFU/ml × 10² (95% CI = 139.19, 550.24), I² = 98.30% at nine months. Streptococcus mutans in CAD/CAM dentures increased from 45.54 CFU/ml × 10² (95% CI = 33.82, 57.25), I² = 87.26% at three months to 125.22 CFU/ml × 10² (95% CI = 38.25, 212.18), I² = 97.89% at nine months. Co-occurrence networks revealed strong Candida albicans-Streptococcus mutans synergy, while Fusobacterium nucleatum showed antagonistic interactions. Heatmaps demonstrated microbial dysbiosis in denture stomatitis cases, with increased Porphyromonas gingivalis and Candida albicans and reduced commensals. Longitudinal analyses highlighted the progressive dominance of opportunistic pathogens, emphasizing the need for early and consistent hygiene interventions.</p><p><strong>Conclusion: </strong>Denture wearers exhibit distinct microbial communities influenced by biofilm formation, denture materials, and hygiene practices. Findings highlight the importance of antimicrobial denture materials and effective cleaning protocols in managing microbial colonization. Given high heterogeneity, standardized methodologies are essential for future research. Frequent professional cleaning and individualized hygiene strategies are necessary to prevent denture-associated infections and maintain oral health.</p>","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sukeshana Srivastav, Nitesh Tewari, Mohammad Atif, Gregory S Antonarakis, Rabindra Man Shrestha, Partha Haldar
{"title":"Knowledge, attitudes and practices of orthodontists regarding orthodontic treatment of traumatized teeth: a systematic review.","authors":"Sukeshana Srivastav, Nitesh Tewari, Mohammad Atif, Gregory S Antonarakis, Rabindra Man Shrestha, Partha Haldar","doi":"10.1038/s41432-025-01166-z","DOIUrl":"10.1038/s41432-025-01166-z","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the global status of the knowledge, attitudes, and practices of orthodontists regarding the orthodontic treatment of traumatized teeth.</p><p><strong>Methods: </strong>An a priori protocol was developed and registered (PROSPERO, CRD42022342038). The literature search based on the Population, Intervention, Comparator, and Outcome (PICO) elements of the research question was developed and conducted electronically in PubMed, LILACS, Web of Science, EMBASE, Scopus, and the Cochrane Library, up to 31st August 2024. Gray literature and reference searches were also performed. Titles and abstracts were screened, and later, full-text articles were identified. Data extraction and analysis were performed, and the risk of bias was analyzed via the Joanna Briggs Institute Critical Appraisal Checklist for cross-sectional analytical studies. The data was synthesized in form of tables and interpretation was performed.</p><p><strong>Results: </strong>From a total of 1272 articles initially identified, six studies qualified for the final synthesis. The awareness of orthodontic treatment of teeth with root fractures, crown fractures, crown‒root fractures, mild and severe injury to the periodontium, and teeth managed by revascularization and root canal treatment was found to be less than 40% in most of the studies. Awareness regarding the risk of resorption in teeth with external inflammatory root resorption and avoiding forces on teeth with ankylosis was greater than 90%. The risk of bias was found to be low in three studies.</p><p><strong>Conclusions: </strong>The knowledge of orthodontists regarding most aspects of orthodontic management of traumatized teeth was found to be low or inadequate. There are wide variations in the protocols preferred, which differ from contemporary recommendations and evidence.</p>","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical periodontal therapy for the management of intrabony/furcation defects with and without topically delivered Alendronate - a systematic review and meta-analysis.","authors":"A Rizwan Ali, Arun Kumar Patnana, Pravin Kumar, Karishma Pathak, Ankita Chugh, Kirti Chaudhry","doi":"10.1038/s41432-025-01165-0","DOIUrl":"https://doi.org/10.1038/s41432-025-01165-0","url":null,"abstract":"<p><strong>Objective: </strong>Alendronate (ALN) are pyrophosphates which prevent bone resorption and aid in periodontal regeneration. The present review aimed to evaluate the success of surgical periodontal therapy in the management of intrabony/ furcation defects with and without topical application of ALN.</p><p><strong>Method: </strong>Using combinations of different search terms, the authors searched the standard electronic databases for randomised controlled trials. Version 2 of the Cochrane risk of bias tool for randomised trials was used for quality appraisal. The random-effects model was used for the statistical analysis of estimated effect sizes. The overall quality of evidence was assessed using GRADEpro GDT software.</p><p><strong>Results: </strong>Nine studies satisfying all inclusion criteria were selected for qualitative analysis, and six studies with homogeneous data were selected for quantitative analysis. The overall risk of bias had \"low\" concerns in one study, \"some\" concerns in four studies, and \"high\" concerns in four studies. The pooled analysis showed that the experimental group showed a significant reduction in periodontal probing depth(PPD) and defect depth(DD) with a standard mean difference(SDM) of 1.06 mm (95% CI, 0.77-1.34; P < 0.00001; I<sup>2</sup> = 0%) and 1.10 mm (95% CI, 0.65-1.54; P < 0.00001; I<sup>2</sup> = 56%) respectively, significant improvement in the clinical attachment level (CAL) with SDM of 1.03 mm (95% CI, 0.42-1.64; P = 0.0009; I2 = 76%).</p><p><strong>Conclusions: </strong>The topical application of ALN has been shown to enhance the effectiveness of surgical periodontal therapy by reducing the PPD and DD and increasing the CAL; however, the certainty of evidence remains very low to low.</p>","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative evaluation of the efficacy of cetylpyridinium chloride and essential oil mouthwashes in reducing plaque and gingivitis: a systematic review and meta-analysis.","authors":"Subhashree Mohapatra, Rahul Mohandas","doi":"10.1038/s41432-025-01163-2","DOIUrl":"https://doi.org/10.1038/s41432-025-01163-2","url":null,"abstract":"<p><strong>Background: </strong>Despite being the gold standard for chemical plaque treatment, chlorhexidine digluconate (CHX) mouthwash has adverse effects that make it necessary to use alternatives. Essential oil (EO) and cetylpyridinium chloride (CPC) mouthwashes effectively reduce plaque and gingivitis. Hence, the aim of this review is to assess and compare the available data on the efficacy of CPC and EO mouthwashes in reducing plaque and gingivitis.</p><p><strong>Methods: </strong>Scopus, PubMed, Cochrane, Science Direct, EBSCOhost, Lilacs, Science Direct, Web of Science, and Google Scholar were searched from the earliest available year (1990) till January 10, 2025. PICO Strategy: P: Individuals with plaque and gingivitis; I: CPC mouthwash; C: EO mouthwash; O: Reduction in plaque and gingivitis. The review only comprised randomised controlled trials. The risk of bias assessment and quality of evidence were assessed using the RoB-2 Tool and GRADE Tool respectively.</p><p><strong>Results: </strong>After meeting the eligibility requirements, seven full-text publications were assessed for qualitative synthesis and six articles for quantitative synthesis. Overall, there was no significant difference in the reduction of plaque and gingivitis between CPC and EO mouthwashes. At two weeks, however, EO demonstrated a greater reduction in gingivitis (SMD: 4.67 [4.08, 5.26]; p < 0.00001; I² = 0%). Both mouthwashes were equally effective at reducing plaque and gingivitis at one, three, and six months.</p><p><strong>Conclusion: </strong>While CPC mouthwash matched EO mouthwash's long-term efficacy, EO mouthwash demonstrated superior short-term anti-gingivitis effects. Both were equally successful in reducing plaque. Depending on the needs of the patient, either can be utilized because of their distinct mechanism of action. Additional research should be done to reduce bias and enhance the methodology.</p><p><strong>Prospero registration no: </strong>CRD42025638243.</p>","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Brushing up on oral health: can messages through social media promote healthy oral health behaviours?","authors":"Niall Nagar, John Linden","doi":"10.1038/s41432-025-01160-5","DOIUrl":"https://doi.org/10.1038/s41432-025-01160-5","url":null,"abstract":"<p><strong>A commentary on: </strong>Choonhawarakorn K, Kasemkhun P, Leelataweewud P. Effectiveness of a message service on child oral health practice via a social media application: a randomized controlled trial. Int J Paediatr Dent 2025; 35: 446-455.</p><p><strong>Background: </strong>The early development of proper oral health behaviours is essential for mitigating the risk of early childhood caries. Interactive social media platforms offer a cost-effective means to support caregivers in this endeavour.</p><p><strong>Aim: </strong>To evaluate the efficacy of a LINE™ messaging service (MS) in promoting positive oral health behaviours among Thai children.</p><p><strong>Design: </strong>A randomised controlled trial was conducted involving 190 caregiver-child dyads (children aged 6-36 months) recruited from a university dental hospital and two affiliated hospitals. Participants were randomly assigned to receive age-appropriate dental health education either via the MS or through conventional in-person visits. The MS group received weekly educational materials, including infographic posters, video clips, and supportive messages. Parental oral health knowledge, along with children's oral health practices and status, were assessed at baseline and after six months.</p><p><strong>Results: </strong>The MS group demonstrated significantly greater improvements in feeding habits (p = 0.034) and toothbrushing practices (p = 0.007) compared to the control group. While parental knowledge improved in both groups, the increase was significantly greater in the control group (p = 0.001). Both groups showed a reduction in debris scores; however, no significant difference was observed in caries progression. Caregivers reported high to very high satisfaction with both methods of education delivery.</p><p><strong>Conclusions: </strong>The LINE™ messaging service was found to be as effective as traditional dental visits in fostering positive oral health behaviours among young children.</p>","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is smoking cessation the key to better oral health outcomes for type 2 diabetic patients with periodontal disease?","authors":"Chris Grumley","doi":"10.1038/s41432-025-01161-4","DOIUrl":"https://doi.org/10.1038/s41432-025-01161-4","url":null,"abstract":"<p><strong>A commentary on: </strong>La Rosa G R M, Pedulla E, Chapple I et al. A systematic review of oral health outcomes following smoking cessation in type 2 diabetes: clinical and research implications. J Dent 2025; https://doi.org/10.1016/j.jdent.2025.105665 .</p><p><strong>Objective: </strong>This systematic review investigated the impact of smoking cessation in patients with type 2 diabetes.</p><p><strong>Methodology: </strong>The review utilised multiple online academic publication search engines and highly cited journals to compile articles for review in accordance with PRISMA guidelines. A combination of human clinical studies, ranging from randomised control trials to cross-sectional studies involving type 2 diabetic patients with a current or past history of smoking, was employed. These studies were analysed to evaluate oral health outcomes related to periodontal disease and caries.</p><p><strong>Results: </strong>Four of the 549 studies analysed met the inclusion criteria (n = 926 participants). Two were cross-sectional analyses of cohort studies, another was a cohort study, and the last was a report. Each assessed a person's smoking status and its effects on the progression of periodontal disease and response to treatment in the type 2 diabetes subgroup. Overall, smoking cessation does not appear to improve the outcomes of periodontal disease or treatment for type 2 diabetics, but the area lacks robust research to draw any significant conclusions.</p><p><strong>Conclusion: </strong>Evidence that smoking cessation improves the outcomes of periodontal treatment in type 2 diabetics remains inconclusive. Smoking cessation is an important method of preventing health problems in the general population, but its effects related to diabetes are still unknown, and more research is necessary.</p>","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Using flavour in your favour: does giving children an element of control help them engage more positively with the dental experience?","authors":"Beth Cunningham, John Linden","doi":"10.1038/s41432-025-01162-3","DOIUrl":"https://doi.org/10.1038/s41432-025-01162-3","url":null,"abstract":"<p><strong>A commentary on: </strong>Karim R, Splieth C H, Schmoeckel J. Effect of choice of flavour of fluoride varnish on behaviour in dental visits in schoolchildren. Clin Exp Dent Res. 2025; https://doi.org/10.1002/cre2.70069 .</p><p><strong>Aim: </strong>To assess the efficacy of giving children choice within the dental surgery to improve behaviour outcomes, investigated by letting them choose the flavour of fluoride varnish (FV). This single-blinded, randomised control trial recruited children attending the specialised paediatric dental service within the Greifswald University Hospital for a dental check-up and preventative FV application. Upon attendance, children were randomly assigned to one of two groups: the control group, where the flavour of FV was predetermined, or the test group, where the children selected their preferred flavour. A blinded observer used Frankl behaviour rating scale (FBRS) to assess behaviour during the appointment, and taste acceptance was assessed using the Facial image scale (FIS).</p><p><strong>Case selection: </strong>70 participants were recruited at the time of their appointment. These were healthy (ASA I or ASA II) German children aged 5 to 10. Exclusion criteria included their first dental experience, experiencing dental pain or an allergy to FV. 35 children were randomly allocated to both groups.</p><p><strong>Results: </strong>Most children, regardless of their allocation, were assessed as positive, or definitely positive according to FBRS (n = 58, 82.8%), though results on behaviour outcomes were statistically insignificant (p = 0.376). There were no significant differences between the control group or the test group on flavour ratings of the FV, with most children (n = 53, 75.7%) scoring happy, or very happy according to FIS. History of negative dental behaviour was also taken into consideration (n = 27), and whilst it appeared children with history of negative experience displayed more positive behaviour in the test group vs the control group (75% vs 54.5%), results were not statistically significant (p = 0.244).</p><p><strong>Conclusion: </strong>This study shows that allowing children a sense of control by permitting them to choose their flavour of FV may be a useful behaviour management tool, though the results are not statistically significant.</p>","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}