MedPulse International Journal of Biochemistry最新文献

{"title":"Correlation of microalbuminuria with glycemic status in diabetic nephropathy","authors":"D. Divija, A. Rajeshwari, A. Nusrath, Somshekhar","doi":"10.26611/1002936","DOIUrl":"https://doi.org/10.26611/1002936","url":null,"abstract":"","PeriodicalId":121008,"journal":{"name":"MedPulse International Journal of Biochemistry","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126028038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antioxidant status of type 2 diabetic patients attending a tertiary care hospital","authors":"T. H. Prasad","doi":"10.26611/10022112","DOIUrl":"https://doi.org/10.26611/10022112","url":null,"abstract":"","PeriodicalId":121008,"journal":{"name":"MedPulse International Journal of Biochemistry","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127400115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Microalbuminuria with glycosylated haemoglobin (HbA1c) among type 2 diabetic patients","authors":"Pampareddy B. Kollur","doi":"10.26611/10021931","DOIUrl":"https://doi.org/10.26611/10021931","url":null,"abstract":"Background: The present study aimed to assess the relationship between Microalbuminuria and HbA1c among type 2 DM patients. Materials and methods: In the present study, 50 type 2 diabetic subjects and 50 healthy non-diabetic subjects were investigated for fasting blood sugar (FBG), and glycosylated hemoglobin (HbA1c), and urinary microalbuminuria (24hr) Results: The mean ± SDs of FBG, HbA1c, and urinary microalbumin, in controls, were in the range of 93.30 ± 10.09, 4.80 ± 0.192, and 25.14 ± 3.55, respectively. It is observed that the mean ± SDs of FBG, HbA1c, and urinary microalbumin, in cases, were in the range of 174.80 ± 9.57, 7.81 ± 1.58, and 120.7 ± 1.58, respectively. It was evident that FBG, HbA1c, and urinary microalbumin levels were increased in cases as compared to controls. The mean ± SD level of FBG, HbA1c, and urinary microalbumin were statistically significantly increased in diabetic cases compared to non-diabetic controls (P<0.0001). Conclusion: The present study concludes that poor glycemic control among type 2 DM patients may lead to the development of microalbuminuria, which in turn brings about changes resulting in progressive renal diseases. The situation can be averted by maintaining good glycemic control and adopting a healthy lifestyle. The study recommends regular screening of HbA1c, microalbuminuria among type 2 diabetic patients for identification and timely management of patients at risk.","PeriodicalId":121008,"journal":{"name":"MedPulse International Journal of Biochemistry","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128801169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of lipid peroxidation and antioxidants on erythrocytes during blood storage","authors":"Chhaya Keny","doi":"10.26611/10021912","DOIUrl":"https://doi.org/10.26611/10021912","url":null,"abstract":"Background: Blood transfusion plays important role in the management of certain clinical conditions like acute blood loss, injury and anemia. The red blood cells (RBCs) for transfusion can be stored for 35 to 42 days at 2–6°C. It has been reported that some biochemical changes occur during the course of storage. During storage, progressive morphological and biochemical changes occur which are often related to the reduction of ATP, 2,3-diphosphoglycerate, and NADH in RBCs. These changes are referred to as the “storage lesions”. Oxidative damage is the most important factor causing RBC storage lesion. Free radicals can damage RBC products by lipid and protein oxidation affecting cell quality. The present study is aimed to study the impact of lipid peroxidation and potential role of enzymatic antioxidants in stored blood. Material and methods: The present study was observational study carried out in healthy blood donors at KEM hospital, Mumbai. Thirty healthy donors, who were fulfilling the inclusion and exclusion criteria, were enrolled in the study. Estimation of hemoglobin, levels of lipid peroxidation and some enzymatic antioxidants like glutathione peroxidase, catalase and superoxide dismutase activity was carried out in a properly stored blood samples at 40C. Enzyme levels estimation was carried out at every 7 days interval. Blood grouping of all the samples was also done to check if there is any change in the levels of lipid peroxidation and antioxidant levels across the groups. Results: Malondialdehyde (MDA) is an indirect marker of lipid peroxidation that can modify proteins. Increased MDA levels in the study indicate that lipid peroxidation in red cells has occurred during the preservation period. Throughout storage period, the levels of glutathione peroxidase and catalase declined. Statistically significant negative correlation existed between lipid peroxidation and glutathione peroxidase. Whereas study established positive correlation between lipid peroxidation and superoxide dismutase (SOD). On day 8, day 15 and day 22, lipid peroxidation was found to be positively correlated with SOD. But on Day 30, there was negative correlation between lipid peroxidation and SOD. Blood grouping of all samples indicate no significant susceptibility to lipid peroxidation when the different blood groups were compared. Methemoglobin levels in stored blood were increased over a period of 30 days. Conclusion: Red cell storage lesions due to oxidative injury during storage are now the reported fact, confirmed by the findings of the present study. This also indicates that antioxidant enzymatic machinery of the system comes into play adequately to circumvent the damage done. To investigate further therapeutic role of antioxidants in preventing oxidative damage to red cells during storage, large sample studies will be required.","PeriodicalId":121008,"journal":{"name":"MedPulse International Journal of Biochemistry","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121395332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hospital based study on prevalence and risk factors for microalbuminuria in type 2 diabetes mellitus patients attending medical college and hospital","authors":"M. Singh, Ila Bhattacharjee","doi":"10.26611/1002912","DOIUrl":"https://doi.org/10.26611/1002912","url":null,"abstract":"","PeriodicalId":121008,"journal":{"name":"MedPulse International Journal of Biochemistry","volume":"124 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123189463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of oxidative stress markers and antioxidant status in smokers","authors":"G. Dhokikar, Pramod W. Ingale, V. Birla","doi":"10.26611/1002922","DOIUrl":"https://doi.org/10.26611/1002922","url":null,"abstract":"","PeriodicalId":121008,"journal":{"name":"MedPulse International Journal of Biochemistry","volume":"183 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116857314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of various biochemical parameters in tuberculosis patients: A hospital based crosssectional study","authors":"K. C. Nakarani, B. S. Rana, Vilas U. Chavan","doi":"10.26611/10021227","DOIUrl":"https://doi.org/10.26611/10021227","url":null,"abstract":"","PeriodicalId":121008,"journal":{"name":"MedPulse International Journal of Biochemistry","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114210384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of serum vitamin D and calcium in chronic otolaryngological diseases","authors":"Arati Ganiger, K. Swamy, A. Maligi","doi":"10.26611/10021032","DOIUrl":"https://doi.org/10.26611/10021032","url":null,"abstract":"","PeriodicalId":121008,"journal":{"name":"MedPulse International Journal of Biochemistry","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129640329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review on diagnosis of lipid profile and non- alcoholic fatty liver disease with special emphasis to ultrasound based on Meta-analysis studies of western countries","authors":"Kavindra Borgaonkar","doi":"10.26611/10022012","DOIUrl":"https://doi.org/10.26611/10022012","url":null,"abstract":"","PeriodicalId":121008,"journal":{"name":"MedPulse International Journal of Biochemistry","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116978591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of coconut oil and palm oil on blood plasma cholesterol in rats","authors":"Neil Jafer, Amin Mohammad, K. Kakarla, A. Ansari","doi":"10.26611/10021011","DOIUrl":"https://doi.org/10.26611/10021011","url":null,"abstract":"This study was carried out to evaluate the effect of coconut oil (Cocosnucifera) and palm oil (Elaeisguineensis) on blood plasma cholesterol levels in white rats (Ratusratus). The results showed that coconut oil has better LDL lowering properties than palm oil, but both have similar HDL raising properties. However when subjected to statistical analysis (t-test and ANOVA test) the results for all parameters tested was not significant. Although coconut oil lowered LDL cholesterol by a greater percentage, the t-test and ANOVA test showed that these results were not significant. There fore to conclude, the experiments need further investigation and verification which would bring out further conclusive evidences towards the effective property of lowering the blood cholesterol level.","PeriodicalId":121008,"journal":{"name":"MedPulse International Journal of Biochemistry","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125790870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}