2型糖尿病患者微量白蛋白尿与糖化血红蛋白(HbA1c)的评估

Pampareddy B. Kollur
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引用次数: 0

摘要

背景:本研究旨在评估2型糖尿病患者微量白蛋白尿与HbA1c的关系。材料与方法:本研究对50例2型糖尿病患者和50例健康非糖尿病患者进行了空腹血糖(FBG)、糖化血红蛋白(HbA1c)和尿微量白蛋白(24hr)的测定。结果:对照组FBG、HbA1c和尿微量白蛋白的平均值±SDs分别为93.30±10.09、4.80±0.192和25.14±3.55。FBG、HbA1c和尿微量白蛋白的平均±SDs分别为174.80±9.57、7.81±1.58和120.7±1.58。与对照组相比,病例中FBG、HbA1c和尿微量白蛋白水平明显升高。糖尿病患者FBG、HbA1c、尿微量白蛋白的平均±SD水平较非糖尿病对照组增高,差异有统计学意义(P<0.0001)。结论:本研究认为2型糖尿病患者血糖控制不良可能导致微量白蛋白尿的发生,微量白蛋白尿的发生改变导致肾脏疾病的进展。这种情况可以通过保持良好的血糖控制和采取健康的生活方式来避免。该研究建议在2型糖尿病患者中定期筛查HbA1c和微量白蛋白尿,以识别和及时管理有风险的患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessment of Microalbuminuria with glycosylated haemoglobin (HbA1c) among type 2 diabetic patients
Background: The present study aimed to assess the relationship between Microalbuminuria and HbA1c among type 2 DM patients. Materials and methods: In the present study, 50 type 2 diabetic subjects and 50 healthy non-diabetic subjects were investigated for fasting blood sugar (FBG), and glycosylated hemoglobin (HbA1c), and urinary microalbuminuria (24hr) Results: The mean ± SDs of FBG, HbA1c, and urinary microalbumin, in controls, were in the range of 93.30 ± 10.09, 4.80 ± 0.192, and 25.14 ± 3.55, respectively. It is observed that the mean ± SDs of FBG, HbA1c, and urinary microalbumin, in cases, were in the range of 174.80 ± 9.57, 7.81 ± 1.58, and 120.7 ± 1.58, respectively. It was evident that FBG, HbA1c, and urinary microalbumin levels were increased in cases as compared to controls. The mean ± SD level of FBG, HbA1c, and urinary microalbumin were statistically significantly increased in diabetic cases compared to non-diabetic controls (P<0.0001). Conclusion: The present study concludes that poor glycemic control among type 2 DM patients may lead to the development of microalbuminuria, which in turn brings about changes resulting in progressive renal diseases. The situation can be averted by maintaining good glycemic control and adopting a healthy lifestyle. The study recommends regular screening of HbA1c, microalbuminuria among type 2 diabetic patients for identification and timely management of patients at risk.
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