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Abstract P070: The safety and efficacy of Durvalumab and Paclitaxel combination in metastatic triple-negative breast cancer: An open-label phase I/II trial with 2-years follow-up P070: Durvalumab和紫杉醇联合治疗转移性三阴性乳腺癌的安全性和有效性:一项为期2年随访的开放标签I/II期试验
Other Topics Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p070
H. Ghebeh, Adher Al-Sayed, Kauser Suleman, Riham Eiada, A. Tulbah, T. Al-Tweigeri
{"title":"Abstract P070: The safety and efficacy of Durvalumab and Paclitaxel combination in metastatic triple-negative breast cancer: An open-label phase I/II trial with 2-years follow-up","authors":"H. Ghebeh, Adher Al-Sayed, Kauser Suleman, Riham Eiada, A. Tulbah, T. Al-Tweigeri","doi":"10.1158/2326-6074.tumimm21-p070","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p070","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123836224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P073: Gut microbiota shift in melanoma patients undergoing immunotherapy is associated with clinical response P073:接受免疫治疗的黑色素瘤患者的肠道微生物群变化与临床反应相关
Other Topics Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p073
A. D. Macandog, C. Catozzi, Ester Cassano, S. Gandini, P. Ferrucci, E. Cocorocchio, T. Manzo, L. Nezi
{"title":"Abstract P073: Gut microbiota shift in melanoma patients undergoing immunotherapy is associated with clinical response","authors":"A. D. Macandog, C. Catozzi, Ester Cassano, S. Gandini, P. Ferrucci, E. Cocorocchio, T. Manzo, L. Nezi","doi":"10.1158/2326-6074.tumimm21-p073","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p073","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"130 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115892938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Abstract P071: Gemcitabine augments HLA class I expression in pancreatic cancer cells through alterations in transcript production and surface stability 摘要:吉西他滨通过改变转录产物和表面稳定性来增加胰腺癌细胞中HLA I类的表达
Other Topics Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p071
Alaina C. Larson, S. Knoche, J. Solheim
{"title":"Abstract P071: Gemcitabine augments HLA class I expression in pancreatic cancer cells through alterations in transcript production and surface stability","authors":"Alaina C. Larson, S. Knoche, J. Solheim","doi":"10.1158/2326-6074.tumimm21-p071","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p071","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122874725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P067: Current status of regulatory-approved immunotherapies in Saudi Arabia P067:沙特阿拉伯监管部门批准的免疫疗法的现状
Other Topics Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p067
R. Ajina
{"title":"Abstract P067: Current status of regulatory-approved immunotherapies in Saudi Arabia","authors":"R. Ajina","doi":"10.1158/2326-6074.tumimm21-p067","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p067","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115941774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P076: Humanized anti-αvβ3 antibody engineered to selectively promote macrophage-mediated cancer cell death P076:人源化抗αvβ3抗体选择性促进巨噬细胞介导的癌细胞死亡
Other Topics Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p076
Hiromi I Wettersten, Ryan M. Shepard, S. Weis, D. Cheresh
{"title":"Abstract P076: Humanized anti-αvβ3 antibody engineered to selectively promote macrophage-mediated cancer cell death","authors":"Hiromi I Wettersten, Ryan M. Shepard, S. Weis, D. Cheresh","doi":"10.1158/2326-6074.tumimm21-p076","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p076","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"142 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121898520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P075: NTX-1088, a potent first-in-class, anti-PVR mAb, restores expression and function of DNAM1 for optimal DNAM1-mediated antitumor immunity P075: NTX-1088是一种有效的抗pvr单抗，可恢复DNAM1的表达和功能，从而获得最佳的DNAM1介导的抗肿瘤免疫
Other Topics Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p075
Pini Tsukerman, A. Atieh, A. Obeidat, K. Paz, G. Cinamon, T. Roviš, Paola Kučan Brlić, L. Hiršl, S. Jonjić, O. Mandelboim
{"title":"Abstract P075: NTX-1088, a potent first-in-class, anti-PVR mAb, restores expression and function of DNAM1 for optimal DNAM1-mediated antitumor immunity","authors":"Pini Tsukerman, A. Atieh, A. Obeidat, K. Paz, G. Cinamon, T. Roviš, Paola Kučan Brlić, L. Hiršl, S. Jonjić, O. Mandelboim","doi":"10.1158/2326-6074.tumimm21-p075","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p075","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"163 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121403092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P077: Composition of CD4 T cell subsets and impact on tumor growth control across mouse syngeneic tumor models P077:小鼠同基因肿瘤模型中CD4 T细胞亚群的组成及其对肿瘤生长控制的影响
Other Topics Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p077
Chunxiao Xu, Lindsay M Webb, Sireesha Yalavarthi, C. Bourin, J. Moisan
{"title":"Abstract P077: Composition of CD4 T cell subsets and impact on tumor growth control across mouse syngeneic tumor models","authors":"Chunxiao Xu, Lindsay M Webb, Sireesha Yalavarthi, C. Bourin, J. Moisan","doi":"10.1158/2326-6074.tumimm21-p077","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p077","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125245007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P066: Prognostic and predictive value of pre-treatment T-Cell receptors (TCR) repertoire in non-small cell lung cancer (NSCLC) patients treated with single agent immunotherapy P066:治疗前t细胞受体(TCR)库在单药免疫治疗非小细胞肺癌(NSCLC)患者中的预后和预测价值
Other Topics Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p066
A. Abed, L. Calapre, S. Bowyer, M. Millward, E. Gray
{"title":"Abstract P066: Prognostic and predictive value of pre-treatment T-Cell receptors (TCR) repertoire in non-small cell lung cancer (NSCLC) patients treated with single agent immunotherapy","authors":"A. Abed, L. Calapre, S. Bowyer, M. Millward, E. Gray","doi":"10.1158/2326-6074.tumimm21-p066","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p066","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123987867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P069: Semi-automated validation and quantification of CTLA-4 in 90 different Tumor entities using multiple antibodies and artificial intelligence P069:基于多抗体和人工智能的CTLA-4在90种不同肿瘤实体中的半自动验证和定量
Other Topics Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p069
D. Dum, Tjark L. C. Henke, T. Mandelkow, E. Bady, J. Raedler, R. Simon, G. Sauter, M. Lennartz, W. Wilczak, E. Burandt, S. Steurer, N. Blessin
{"title":"Abstract P069: Semi-automated validation and quantification of CTLA-4 in 90 different Tumor entities using multiple antibodies and artificial intelligence","authors":"D. Dum, Tjark L. C. Henke, T. Mandelkow, E. Bady, J. Raedler, R. Simon, G. Sauter, M. Lennartz, W. Wilczak, E. Burandt, S. Steurer, N. Blessin","doi":"10.1158/2326-6074.tumimm21-p069","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p069","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129832219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Abstract P072: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) foster myeloid-derived suppressor cell-mediated tumor immune evasion in cholangiocarcinoma 肿瘤坏死因子相关凋亡诱导配体(TRAIL)在胆管癌中促进髓源性抑制细胞介导的肿瘤免疫逃避
Other Topics Pub Date : 2022-01-01 DOI: 10.1158/2326-6074.tumimm21-p072
E. Loeuillard, Juan Wang, Jingchun Yang, Haidong Dong, G. Gores, S. Ilyas
{"title":"Abstract P072: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) foster myeloid-derived suppressor cell-mediated tumor immune evasion in cholangiocarcinoma","authors":"E. Loeuillard, Juan Wang, Jingchun Yang, Haidong Dong, G. Gores, S. Ilyas","doi":"10.1158/2326-6074.tumimm21-p072","DOIUrl":"https://doi.org/10.1158/2326-6074.tumimm21-p072","url":null,"abstract":"","PeriodicalId":120683,"journal":{"name":"Other Topics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129010532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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