European Journal of Trauma and Emergency Surgery最新文献

{"title":"Timely enteral nutrition of ventilated polytrauma patients: current standards and room for improvements.","authors":"Ottavio de la Vega, Saskia Ridley-Smith, Howard Huang, Daniel Hali, Simone Meakes, Cino Bendinelli, Zsolt J Balogh","doi":"10.1007/s00068-025-02849-z","DOIUrl":"https://doi.org/10.1007/s00068-025-02849-z","url":null,"abstract":"<p><strong>Purpose: </strong>Polytrauma patients in intensive care units (ICUs) face significant risks of morbidity and mortality, with nutrition playing a crucial role in mitigating energy deficits and complications such as multi-organ failure (MOF). This study aimed to evaluate adherence to enteral nutrition (EN) guidelines in ventilated polytrauma patients and explored correlations between EN timing and clinical outcomes.</p><p><strong>Methods: </strong>A four-year retrospective (2019-2022) analysis of ventilated polytrauma patients (abbreviated injury scale > 2 in ≥ 2 body regions) admitted to a level 1 trauma centre. Collected data included demographics, injury characteristics and EN patterns. Early EN was defined as started withing 24 h. Statistical analysis assessed associations between EN, injury severity, and outcomes such as ICU length of stay (LOS), mortality, and MOF.</p><p><strong>Results: </strong>Of 182 patients (median age 41, male 77%, median ISS 34), 41 did not receive EN and were excluded. Of the remaining 141, 64% received early EN, with a median time to EN of 17.8 h. Early EN was associated with reduced ICU LOS (p = 0.016). Delaying EN initiation correlated with higher injury severity (p = 0.008). Each one-hour delay to EN increased MOF odds by 1.47% (OR: 1.0147, p = 0.07). EN interruptions (> 6 h) occurred 354 times.</p><p><strong>Conclusion: </strong>Investigations into current EN standards in polytrauma patients demonstrated an average of 2.5 interruptions in EN exceeding 6 h per patient, with 40% not fed within 24 h. Combined with inconsistent dietician input, this offers room for improvement as early EN is associated with better outcomes, with a reduced ICU LOS established through this study.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"169"},"PeriodicalIF":1.9,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor regarding the Alvarado and AIR score in pregnant women.","authors":"Roland E Andersson, Elin Moltubak, Kalle Landerholm","doi":"10.1007/s00068-025-02851-5","DOIUrl":"https://doi.org/10.1007/s00068-025-02851-5","url":null,"abstract":"<p><p>This letter to the Editor is a comment to the report by Kahana N et al. evaluating the diagnostic properties of the Alvarado and AIR score in pregnant women. The AIR score is not correctly described. This has important implications for the interpretation of the study results.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"168"},"PeriodicalIF":1.9,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of adenosine A₃ receptor and endothelial nitric oxide synthase in patients with traumatic hemorrhagic shock.","authors":"Yasin Öztaş, Yusuf Ertuğrul Aslan, Elif Funda Şener, Halime Dana, Emre Tuğhan, Nurullah Günay, Abdullah Tuncay Demiryürek","doi":"10.1007/s00068-025-02853-3","DOIUrl":"https://doi.org/10.1007/s00068-025-02853-3","url":null,"abstract":"<p><strong>Background: </strong>The aim of this research is to access the expression of adenosine A3 receptor (ADORA3) and nitric oxide synthase 3 (NOS3) genes and serum levels of ADORA3 and NOS3 in patients with multiple trauma with hemorrhagic shock.</p><p><strong>Materials and methods: </strong>The study was performed at Erciyes University between November 2022 and March 2024, in a prospective and controlled manner. Patients diagnosed with traumatic hemorrhagic shock and requiring transfusion in the emergency department were selected as the patients group. Gene expressions were analyzed using quantitative real-time PCR analysis in total RNA samples and serum levels of NOS3 and ADORA3 were detected using ELISA measurements.</p><p><strong>Results: </strong>In patients with multiple trauma, adenosine A3 receptor (ADORA3) gene expression showed a significant increase at discharge when compared to healthy controls (P < 0.05). However, serum levels of ADORA3 showed significant decreases at all stages (i.e. at admission, at 24 h, and at discharge) of patients. Although no significant changes were detected in NOS3 gene expression, marked decreases in serum NOS3 levels were observed at admission and at 24 h in multiple trauma patients (P < 0.05). ADORA3 and NOS3 gene expressions were found to be significantly diminished in nonsurvivors.</p><p><strong>Conclusion: </strong>The study emphasizes the importance of ADORA3 and NOS3 gene expressions in influencing shock progression in multiple trauma patients. The increase in ADORA3 gene expression may play a role in restoring vascular reactivity after traumatic shock. Decreased serum NOS3 and ADORA3 levels can contribute to the shock progression in the pathophysiology of multiple trauma.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"167"},"PeriodicalIF":1.9,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Answer to letter to the editor regarding \"A retrospective chart analysis with 5-year follow-up of early care for geriatric hip fracture patients: why we should continue talking about hip fractures.\"","authors":"An Sermon, Harm Hoekstra","doi":"10.1007/s00068-025-02842-6","DOIUrl":"https://doi.org/10.1007/s00068-025-02842-6","url":null,"abstract":"","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"162"},"PeriodicalIF":1.9,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of Tranexamic acid use on postoperative blood transfusion in hip fracture patients- a systematic review and meta-analysis.","authors":"Christian A Klingemann, Jes B Lauritzen, Henrik L Jørgensen","doi":"10.1007/s00068-025-02846-2","DOIUrl":"https://doi.org/10.1007/s00068-025-02846-2","url":null,"abstract":"<p><strong>Purpose: </strong>This systematic review seeks to investigate whether tranexamic acid (TXA) should be administered to patients over 65 years of age undergoing hip fracture surgery. This select patient population is at increased risk of requiring red blood cell transfusions, why there might be a case for TXA intervention.</p><p><strong>Methods: </strong>Following PRISMA guidelines, a systematic search was conducted on EMBASE and PubMed databases on the 27th of November 2023. Only randomized controlled trials (RCT) with a mean age of above 65 years where eligible for inclusion. Only studies with intravenous intervention and control with saline were included. A Cochrane Risk of Bias tool was used to investigate potential biases. The certainty of each outcome was interpreted using the GRADE approach. The primary outcome was red blood cell transfusion rate and the secondary outcome was thromboembolic event rate.</p><p><strong>Results: </strong>This review comprised of 12 RCTs with a combined 1397 patients, of whom 699 received TXA and 698 received saline. Pooled results show a significant reduction in blood transfusion rate for patients who received TXA (RR 0.612, 95%CI 0.480-0.779, p-value < 0.001). Thromboembolic event rate was reported in 9 studies, tallying 1147 patients. Results showed no significant change in thromboembolic event rate for patients receiving TXA intervention (RR 0.922, 95%CI 0.603-1.411, p-value = 0.710).</p><p><strong>Conclusion: </strong>Tranexamic acid significantly reduced the need for blood transfusion in patients undergoing hip fracture surgery. Furthermore, no significant change in thromboembolic events is present, but due to low thromboembolic event rate in the patient population, no definite conclusion can be made regarding the safety of tranexamic acid. Furthermore, a higher grade of homogeneity between studies with regards to TXA intervention timing and dose would be helpful. In conclusion, intervention with TXA appears promising with regards to transfusion requirement in the targeted population.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"164"},"PeriodicalIF":1.9,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distinct patterns of ligament and meniscal injuries in multiligamentous knee injuries with and without dislocation: a 15-year retrospective study.","authors":"Jae Ang Sim, Sang-Jin Lee, Jung-Min Shin, Byung Hoon Lee","doi":"10.1007/s00068-024-02740-3","DOIUrl":"10.1007/s00068-024-02740-3","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to compare the incidence rates of concomitant injuries, including meniscal and cartilage injuries, between multiligamentous knee injuries (MLKI) with and without dislocation based on our 15-year experience of knee dislocation and MLKI at a level 1 trauma center.</p><p><strong>Methods: </strong>We retrospectively identified 100 patients (115 knees) with MLKIs and/or dislocations at our trauma center between 2007 and 2021. Magnetic resonance imaging was routinely performed to evaluate the injured structures and extent of injury. The anatomic structures of the knee were categorized into anterior and posterior cruciate ligaments (ACL, PCL) and medial and posterolateral structures, and further classified according to the modified Schenck classification. The study participants were divided into two groups: 40 and 75 knees classified as MLKI with and without dislocation, respectively.</p><p><strong>Results: </strong>MLKIs with dislocations showed 13% (5/40 knees) and 18% (7/40 knees) incidence, whereas MLKIs without dislocation showed 15% (11/75 knees) and 13% (10/75 knees) incidence of medial and lateral meniscal tears respectively. The two groups also had a significant discrepancy in the patterns of meniscal tears. For medial meniscal tears, radial tears were more prevalent in MLKIs with dislocation, and longitudinal tears in MLKIs without dislocation (p = 0.197). For lateral meniscal tears, anterior horn or totally detached tears were more prevalent in MLKIs with dislocation, and radial tears in MLKIs without dislocation (p = 0.026). Additionally, complete rupture of all four major ligaments was found in 38% (15/40 knees) of the cases with dislocation, with the majority showing complete ruptures of both the ACL and PCL. Concomitant serious injuries, such as popliteal artery injury and fractures, were observed only in cases involving high-energy trauma and dislocation.</p><p><strong>Conclusions: </strong>MLKIs with dislocation show distinct ligament and meniscal injury patterns compared to those without, highlighting the importance of severity and anatomical classification in diagnosing associated knee injuries.</p><p><strong>Clinical relevance: </strong>The initial distinction in the severity of MLKIs, along with the anatomical classification, have practical implications in identifying associated meniscal tears and injuries to structures surrounding the knee joint.</p><p><strong>Level of evidence: </strong>IV Retrospective comparative study.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"163"},"PeriodicalIF":1.9,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Education and continued professional development.","authors":"Christina Gaarder, Pål Aksel Naess, Ingo Marzi, Falco Hietbrink","doi":"10.1007/s00068-025-02831-9","DOIUrl":"10.1007/s00068-025-02831-9","url":null,"abstract":"<p><p>Trauma care requires a multidisciplinary approach, with surgeons ensuring timely and effective treatment for severely injured patients while collaborating closely with intensivists, emergency physicians, and rehabilitation teams. In addition to advanced surgical skills, trauma surgeons develop non-technical competencies such as leadership, communication, and decision-making to coordinate care effectively. This chapter addresses the challenges of maintaining trauma surgical competence in Europe, focusing on essential training programmes, quality improvement initiatives, and interdisciplinary collaboration. It also examines the impact of an ageing population, the integration of new technologies, and the vital role of surgical involvement in intensive care units (ICUs). Structured education and continuous professional development are critical to improving outcomes for trauma patients. ESTES, Polytrauma, Whitebook.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"166"},"PeriodicalIF":1.9,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating factors associated with the use of extracorporeal membrane oxygenation in major trauma - an analysis of the TraumaRegister DGU^®.","authors":"Maximilian Feth, Philipp M Lepper, Christine Eimer, Andreas K Bauer, Ralf Muellenbach, Jonas Ajouri, Matthias Ring, Gerhard Achatz, Jonathan Schober, Rolf Lefering, Bjoern Hossfeld, Martin Kulla","doi":"10.1007/s00068-025-02844-4","DOIUrl":"10.1007/s00068-025-02844-4","url":null,"abstract":"<p><strong>Purpose: </strong>There is increasing evidence that use of ECMO is beneficial in major trauma patients with refractory organ failure. Hence, increased numbers of ECMO support following major trauma are reported. We set out to determine the use of ECMO among major trauma patients submitted to the TraumaRegister DGUr^® as well as patient features associated with ECMO support.</p><p><strong>Methods: </strong>The TraumaRegister DGU^® is a multinational database compiling trauma related health care data from point-of-injury, initial and critical care to outcome. Major trauma cases (AIS ≥ 3 irrespective of injury location) with subsequent critical care as well as respiratory and/or circulatory failure (SOFA score ≥ 3 per respective category) enrolled in the TraumaRegister DGU^® between 2015 and 2022 were reviewed. A logistic regression model was carried out to evaluate patient features associated with ECMO support.</p><p><strong>Results: </strong>410/ 22,548 individuals (1.8%) received ECMO support. Survival among ECMO patients was 46.1%. At discharge, good functional outcome as indicated by a Glasgow outcome scale > 3 was observed for 97 ECMO patients (23.6%). Age > 65 (OR 95%-CI 1.90, 1.52-2.60), male sex (OR 1.49, 95%-CI 1.41-1.95), coagulopathy at admission to the emergency department (OR 2.37, 95%-CI 1.88-3.00), chest trauma (OR 2.12, 95%-CI 1.61-2.81), sepsis (OR 2.94, 95%-CI 1.93-2.97), as well as massive transfusion (OR 2.23, 95%-CI1.56-3.19) were associated with the use of ECMO following trauma.</p><p><strong>Conclusion: </strong>In the TraumaRegister DGU^®, ECMO for trauma related organ failure remains rare. Among ECMO patients, good functional outcome was observed infrequently. However, the design of the registry did not allow for capturing granular data on ECMO management and timing of organ failure. Hence, outcome data should be interpreted with caution. Nevertheless, evaluation of factors associated with ECMO support after trauma might contribute to early identification of ECMO candidates and improve patient distribution for trauma centers without ECMO capability.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"165"},"PeriodicalIF":1.9,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The medial clearspace is a risk factor for secondary dislocation following cast immobilization after closed reduction in closed ankle fracture dislocations.","authors":"Verena Hecht, Eléonore Sophie Mosimann, Fabian Krause, Christophe Kurze, Thomas Lustenberger, Helen Anwander","doi":"10.1007/s00068-025-02803-z","DOIUrl":"10.1007/s00068-025-02803-z","url":null,"abstract":"<p><strong>Purpose: </strong>Ankle fractures represent about 10% of all adult fractures, with increasing incidence. Dislocated ankle fractures often require delayed open reduction and internal fixation due to swelling, necessitating temporary stabilization using a cast or an external fixator. This study aims to assess risk factors for insufficient preliminary reduction immobilized by a cast, focusing on medial clearspace and posterior malleolus fragment size, to identify fractures that would benefit from initial stabilization with an external fixator.</p><p><strong>Methods: </strong>Patients treated for dislocated ankle fractures at our level-1 trauma center from 2011 to 2023 were retrospectively reviewed. The primary outcome was the rate of insufficient reduction during immobilization in a cast. Secondary outcomes included time to definitive surgery, length of surgery and hospital stay.</p><p><strong>Results: </strong>134 patients met the inclusion criteria. The most common fracture type was AO 44B3, with 71.6%. Sufficient reduction was achieved in 53.7% of patients. Multiple regression analyses revealed the initial medial clearspace at the time of dislocation as an independent risk factor for insufficient reduction after reduction. ROC-analysis revealed that a initial medial clearspace at the time of dislocation of 9 mm is a predictor for insufficient reduction with a sensitivity of 88% and a specificity of 55%.</p><p><strong>Conclusion: </strong>Initial medial clearspace was an important predictor for insufficient reduction in a cast, with 9 mm being identified as the cutoff for critical initial medial clearspace. Therefore, we recommend primary external fixation or acute internal fixation, if the soft tissue allows it for those patients with initial medial clearspace of > 9 mm. This approach may prevent secondary dislocation, reduce swelling, and expedite definitive surgery.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"161"},"PeriodicalIF":1.9,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11968475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143771860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What is the patient-reported outcome, complication rate and conversion to total knee arthroplasty in patients with tibial plateau fractures caused by high-energy compared to low-energy mechanisms of injury?","authors":"Thijs P Vaartjes, Tijmen W Kraai, Eelke Bosma, Fabian J van der Sluis, Joost G Ten Brinke, Reinier de Groot, Harm Hoekstra, Job N Doornberg, Nick Assink, Frank F A IJpma","doi":"10.1007/s00068-025-02810-0","DOIUrl":"10.1007/s00068-025-02810-0","url":null,"abstract":"<p><strong>Purpose: </strong>Despite varying impact of high- and low-energy traumas, research comparing patient and fracture characteristics as well as patient-reported functional outcomes following these trauma mechanisms is limited. From a patient, doctor, and legal perspective, assessing the association between trauma mechanism and clinical outcome is important for managing expectations.</p><p><strong>Methods: </strong>A multicenter cross-sectional study was performed including 1066 patients treated for a tibial plateau fracture between 2003 and 2019. Patients completed the Knee injury and Osteoarthritis Outcomes Score (KOOS) at a mean follow-up of 6 ± 4 years. Trauma mechanisms were classified according to ATLS guidelines. Independent- samples t-test and chi-square test were used to assess differences in patient and fracture characteristics after high- or low-energy trauma. Linear regression analyzed the relationship between trauma mechanisms and KOOS-scores. The Fisher's exact assessed differences in complications and conversion to total knee arthroplasty (TKA).</p><p><strong>Results: </strong>High-energy trauma mostly occurred in younger males and low-energy trauma in older females. High-energy trauma caused more Schatzker IV-VI fractures, resulted in more initial fracture displacement and needed more often surgical treatment (81% versus 67%; p = 0.002). Linear regression showed that high-energy trauma was associated with lower KOOS-scores. Patients after high-energy trauma had more complications (e.g. revision surgery [8% versus 2%; p =  < 0.001], mal- or nonunion [8% versus 2%; p =  < 0.001]) and conversion to TKA (15% versus 10%; p = 0.144).</p><p><strong>Conclusion: </strong>Only 12% of patients with tibial plateau fractures sustained these injuries due to high-energy trauma, which predominantly involved younger males and resulted in more severe fractures. High-energy trauma resulted in worse patient-reported outcomes, more complications, and conversions to TKA.</p><p><strong>Level of evidence: </strong>Level III, prognostic study.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"160"},"PeriodicalIF":1.9,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11968463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143771862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}