{"title":"Advances in Atrial Fibrillation-related Stroke Prevention","authors":"P. Amarenco, W. Hacke, B. Norrving, N. Rost","doi":"10.17925/ENR.2014.09.02.122","DOIUrl":"https://doi.org/10.17925/ENR.2014.09.02.122","url":null,"abstract":"","PeriodicalId":12047,"journal":{"name":"European neurological review","volume":"9 1","pages":"122"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67591197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Yannick, Kamgang Fogoum Alain, N. Moustapha, D. Gallo, N. M. Mansour
{"title":"Selective Attention and Mental Flexibility are Reduced during the Interictal Period in Migraine","authors":"F. Yannick, Kamgang Fogoum Alain, N. Moustapha, D. Gallo, N. M. Mansour","doi":"10.17925/ENR.2015.10.02.204","DOIUrl":"https://doi.org/10.17925/ENR.2015.10.02.204","url":null,"abstract":"Background: Headache patients frequently complain about difficulties in attention and concentration, even when they are headache free, and psychometric studies concerning attentional deficits in migraine patients between attacks are scarce. Objective: To evaluate selective attention of migraine patients interictally and compare them with healthy volunteers. Patients and Methods: We performed, between February 2011 and July 2011, a case-control study including 45 university students suffering from migraine matched with 45 healthy students as controls. Migraine patients were evaluated in an interictal state. Subjects with another headache type, history of brain injury, epilepsy and visual disturbances were excluded. Mood disorders were assessed using the Hospital Anxiety and Depression (HAD) questionnaire. Selective attention was evaluated using the Delis–Kaplan Executive Functions System (D-KEFS) colour-word interference test. Results: Mean age of patients was 23.29±2.55 years, versus 22.89±2.04 years for controls (p=0.2). The selective attention score was −4.04±7.08 for patients, versus −1.31±7.73 for controls (p=0.02). The mean mental flexibility score was lower in migraine patients compared with controls (36.67±6.79 versus 41.33±6.23; p=0.01). Gender, anxiety, depression scores and migraine characteristics had no correlation with the selective attention score. Conclusion: Selective attention and mental flexibility capacities are significantly reduced in migraine patients during the interictal period. These abnormalities probably contribute to frequent attentional complaints among these patients.","PeriodicalId":12047,"journal":{"name":"European neurological review","volume":"114 1","pages":"204"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67591632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum to: Effect of Therapeutic Interventions on Health-related Quality of Life in Parkinson’s Disease","authors":"H. Reichmann, P. Martínez-Martín, F. Stocchi","doi":"10.17925/ENR.2014.09.02.156","DOIUrl":"https://doi.org/10.17925/ENR.2014.09.02.156","url":null,"abstract":"","PeriodicalId":12047,"journal":{"name":"European neurological review","volume":"9 1","pages":"156"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67590916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"European Academy of Neurology (EAN) The First Congress Is Approaching","authors":"A. Sauerbier","doi":"10.17925/ENR.2015.10.01.10","DOIUrl":"https://doi.org/10.17925/ENR.2015.10.01.10","url":null,"abstract":"Disclosure: Anna Sauerbier is a member of the European Academy of Neurology (EAN) Liaison committee and an active member of the European Association of Young Neurologists and Trainees (EAYNT). Anna Sauerbier has no conflicts of interest to declare. No funding was received for the publication of this article. Open Access: This article is published under the Creative Commons Attribution Noncommercial License, which permits any non-commercial use, distribution, adaptation and reproduction provided the original author(s) and source are given appropriate credit. Received: 20 March 2015 Accepted: 2 April 2015 Citation: European Neurological Review, 2015;10(1):10–1 Correspondence: Anna Sauerbier, Department of Neurology, 9th Floor, Ruskin Wing, King’s College Hospital, Denmark Hill, London SE5 9RS, UK. E: annasauerbier@nhs.net","PeriodicalId":12047,"journal":{"name":"European neurological review","volume":"10 1","pages":"10"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67590934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vitamin D Deficiency and Possible Role in Multiple Sclerosis","authors":"M. Holick, S. Cook, G. Suárez, M. Rametta","doi":"10.17925/ENR.2015.10.02.131","DOIUrl":"https://doi.org/10.17925/ENR.2015.10.02.131","url":null,"abstract":"TOUCH MEDICAL MEDIA • Despite a lack of consensus, vitamin D deficiency and insufficiency have been defined as a serum level of 25-hydroxyvitamin D (25[OH]D) <50 nmol/L or 52.5–72.5 nmol/L respectively. • Vitamin D deficiency is widespread. • Vitamin D is probably involved in the prevention of numerous disease states. • Most primary care clinicians are unaware of the recommended dose for vitamin D supplementation or the optimum serum level in multiple sclerosis (MS) patients. • In the general population management of vitamin D deficiency in children and adults can be effectively achieved by administering 50,000 IU vitamin D2 or vitamin D3 once a week for 6 or 8 weeks respectively: – In the general population 600–1,000 IU/d is effective to prevent recurrence in children and 50,000 IU vitamin D3 or vitamin D2 every 2 weeks (equivalent to approximately 3,600 IU daily) in adults. This strategy maintains blood levels of 25(OH)D at approximately 100–150 nmol/L for up to 6 years with no evidence of toxicity. – In pregnant women supplementation with 2,000 and 4,000 IU/d during pregnancy improve maternal/ neonatal vitamin D status. • Considerable evidence exists for the protective effects of vitamin D in MS, with higher sun exposure and vitamin D intake associated with a lower risk of MS. • Improvement in 25(OH)D status appears to additively enhance the beneficial effects of interferon-beta. To date, this effect has not as yet been observed with glatiramer acetate. • Results from the Betaferon/Betaseron in Newly Emerging multiple sclerosis For Initial Treatment (BENEFIT) study showed that patients with vitamin D levels (25[OH]D) <50 nmol/L had more prominent clinical and MRI disease activity.","PeriodicalId":12047,"journal":{"name":"European neurological review","volume":"10 1","pages":"131"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67591262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cognitive Impairment in Multiple Sclerosis","authors":"T. Santos, J. Pinheiro, P. Barros","doi":"10.17925/ENR.2015.10.02.157","DOIUrl":"https://doi.org/10.17925/ENR.2015.10.02.157","url":null,"abstract":"Multiple sclerosis (MS) is a chronic inflammatory demyelinating disorder of the central nervous system. Although MS has been known since the 19th century, cognitive impairment (CI) was only recognised as an important feature of MS over the past 30 years. The reason is that, until recently, MS was perceived exclusively as a white matter disease, and cognition was thought to depend solely on the cortex. This article aims to review the prevalence, risk factors, profile and diagnosis of CI in MS. Imaging correlates and treatment will also be briefly discussed.","PeriodicalId":12047,"journal":{"name":"European neurological review","volume":"10 1","pages":"157"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67591393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New Directions in Research and Therapies in Traumatic Brain Injury","authors":"J. Thome, D. Muresanu","doi":"10.17925/ENR.2015.10.01.56","DOIUrl":"https://doi.org/10.17925/ENR.2015.10.01.56","url":null,"abstract":"","PeriodicalId":12047,"journal":{"name":"European neurological review","volume":"10 1","pages":"56"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67591427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimising Epilepsy Therapy – Searching for the Evidence – Looking Beyond the Data","authors":"M. Carreño, E. Trinka, M. Holtkamp","doi":"10.17925/ENR.2015.10.02.164","DOIUrl":"https://doi.org/10.17925/ENR.2015.10.02.164","url":null,"abstract":"","PeriodicalId":12047,"journal":{"name":"European neurological review","volume":"10 1","pages":"164"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67591443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treating drug-resistant epilepsy - Why are we waiting?","authors":"P. Boon, P. Ryvlin, J. Wheless, K. Kawai","doi":"10.17925/ENR.2015.10.02.171","DOIUrl":"https://doi.org/10.17925/ENR.2015.10.02.171","url":null,"abstract":"","PeriodicalId":12047,"journal":{"name":"European neurological review","volume":"12 1","pages":"171-175"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67591487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neuroplasticity – Basis for Lifelong Learning","authors":"J. Kesselring","doi":"10.17925/ENR.2014.09.02.143","DOIUrl":"https://doi.org/10.17925/ENR.2014.09.02.143","url":null,"abstract":"Neuroplasticity is the continuous adaptation of synaptic networks to the requirements from internal external environment. It is the basis of learning. Neurorehabilitation is its clinical application.","PeriodicalId":12047,"journal":{"name":"European neurological review","volume":"9 1","pages":"143"},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67590849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}