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83 (PB071): Preclinical characterization of SMARCA2-selective monovalent direct degraders 83 (PB071)：SMARCA2 选择性单价直接降解剂的临床前表征
IF 7.6 1区 医学
European Journal of Cancer Pub Date : 2024-10-01 DOI: 10.1016/j.ejca.2024.114609
G. Parker, G. Leriche, T. Kampert, A. Jamborcic, L. Yang, J. Toth, K. Steadman, J. Chung, D. Tran, L. Luis, F. Barmare, K. Hayashi, G. Liu, J. Ma, A. Campos, M. McCarrick, V. Kumar, K. Freeman-Cook, P. Thompson
{"title":"83 (PB071): Preclinical characterization of SMARCA2-selective monovalent direct degraders","authors":"G. Parker, G. Leriche, T. Kampert, A. Jamborcic, L. Yang, J. Toth, K. Steadman, J. Chung, D. Tran, L. Luis, F. Barmare, K. Hayashi, G. Liu, J. Ma, A. Campos, M. McCarrick, V. Kumar, K. Freeman-Cook, P. Thompson","doi":"10.1016/j.ejca.2024.114609","DOIUrl":"10.1016/j.ejca.2024.114609","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 114609"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
19 (PB007): The SRG Rat, an immunodeficient model for orthotopic glioblastoma, diffuse intrinsic pontine glioma (DIPG) PDX, and intracranial metastatic breast cancer PDX tumors 19 (PB007)：SRG 大鼠，一种用于正位胶质母细胞瘤、弥漫性桥脑胶质瘤 (DIPG) PDX 和颅内转移性乳腺癌 PDX 肿瘤的免疫缺陷模型
IF 7.6 1区 医学
European Journal of Cancer Pub Date : 2024-10-01 DOI: 10.1016/j.ejca.2024.114548
D. Begemann, N. Fulcher, E. Fenton, C. Dunn, D. Robertson, C. Scutchfield, T. Keener, A. Deweyert, A. Elsaleh, H. Xu, C. De Oliveira, J. Kelly, J.A. Ronald, R.G. Walton, S. Sampathi, V. Steffey, M.J. Schlosser, S. Schmid, M.O. Hebb, F. Noto
{"title":"19 (PB007): The SRG Rat, an immunodeficient model for orthotopic glioblastoma, diffuse intrinsic pontine glioma (DIPG) PDX, and intracranial metastatic breast cancer PDX tumors","authors":"D. Begemann, N. Fulcher, E. Fenton, C. Dunn, D. Robertson, C. Scutchfield, T. Keener, A. Deweyert, A. Elsaleh, H. Xu, C. De Oliveira, J. Kelly, J.A. Ronald, R.G. Walton, S. Sampathi, V. Steffey, M.J. Schlosser, S. Schmid, M.O. Hebb, F. Noto","doi":"10.1016/j.ejca.2024.114548","DOIUrl":"10.1016/j.ejca.2024.114548","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 114548"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
25 (PB013): Design, development and characterization of novel CAR T cells targeting globo-H for solid tumor cell therapy 25 (PB013)：设计、开发和鉴定用于实体瘤细胞治疗的靶向球-H 的新型 CAR T 细胞
IF 7.6 1区 医学
European Journal of Cancer Pub Date : 2024-10-01 DOI: 10.1016/j.ejca.2024.114553
F. Putti, F. Zonca, M. Figini, E. Luison, F. De Santis, M. Di Nicola
{"title":"25 (PB013): Design, development and characterization of novel CAR T cells targeting globo-H for solid tumor cell therapy","authors":"F. Putti, F. Zonca, M. Figini, E. Luison, F. De Santis, M. Di Nicola","doi":"10.1016/j.ejca.2024.114553","DOIUrl":"10.1016/j.ejca.2024.114553","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 114553"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
66 (PB054): Synergistic effect of JIN-001, a novel HPS90 selective inhibitor, with platinum or paclitaxel on multi-resistant ovarian cancer 66（PB054）：新型 HPS90 选择性抑制剂 JIN-001 与铂类或紫杉醇对多耐药性卵巢癌的协同作用
IF 7.6 1区 医学
European Journal of Cancer Pub Date : 2024-10-01 DOI: 10.1016/j.ejca.2024.114593
J. Kim, H.Y. Shin, A. Jo, E. Seah, C. Kim, J.H. Kim
{"title":"66 (PB054): Synergistic effect of JIN-001, a novel HPS90 selective inhibitor, with platinum or paclitaxel on multi-resistant ovarian cancer","authors":"J. Kim, H.Y. Shin, A. Jo, E. Seah, C. Kim, J.H. Kim","doi":"10.1016/j.ejca.2024.114593","DOIUrl":"10.1016/j.ejca.2024.114593","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 114593"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
54 (PB042): The Application of Small Molecule ClpP Agonists as Novel Anti-Cancer Agents 54 (PB042)：小分子 ClpP 激动剂作为新型抗癌药物的应用
IF 7.6 1区 医学
European Journal of Cancer Pub Date : 2024-10-01 DOI: 10.1016/j.ejca.2024.114581
L. Graves, S. Daglish, O. Canterbury, A. Mistreanu, P. Graves, E. Iwanowicz
{"title":"54 (PB042): The Application of Small Molecule ClpP Agonists as Novel Anti-Cancer Agents","authors":"L. Graves, S. Daglish, O. Canterbury, A. Mistreanu, P. Graves, E. Iwanowicz","doi":"10.1016/j.ejca.2024.114581","DOIUrl":"10.1016/j.ejca.2024.114581","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 114581"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Copyright Page 版权页
IF 7.6 1区 医学
European Journal of Cancer Pub Date : 2024-10-01 DOI: 10.1016/j.ejca.2024.115025
{"title":"Copyright Page","authors":"","doi":"10.1016/j.ejca.2024.115025","DOIUrl":"10.1016/j.ejca.2024.115025","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 115025"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142526483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
8 Oral: ALTA3263: an oral, KRAS isoform-selective, dual ON/OFF state, noncovalent inhibitor induces regressions across KRAS G12V, G12D, and G12C cancer models 8 口服：ALTA3263：一种口服的、具有 KRAS 同工酶选择性的、双重 ON/OFF 状态的非共价抑制剂，可诱导 KRAS G12V、G12D 和 G12C 癌症模型的消退
IF 7.6 1区 医学
European Journal of Cancer Pub Date : 2024-10-01 DOI: 10.1016/j.ejca.2024.114537
T. Wang, M. Ibanez, K. Yu, K. Fan, J. Juan, M. Perez, T. Smith, B. Walsh, V. Kang, J. Tyhonas, N. Alvarez, J. Tran, K.S. Moorefield, A. Phimister, X. Zhu, A. Chi, M.D. Bartberger, E. Murphy
{"title":"8 Oral: ALTA3263: an oral, KRAS isoform-selective, dual ON/OFF state, noncovalent inhibitor induces regressions across KRAS G12V, G12D, and G12C cancer models","authors":"T. Wang, M. Ibanez, K. Yu, K. Fan, J. Juan, M. Perez, T. Smith, B. Walsh, V. Kang, J. Tyhonas, N. Alvarez, J. Tran, K.S. Moorefield, A. Phimister, X. Zhu, A. Chi, M.D. Bartberger, E. Murphy","doi":"10.1016/j.ejca.2024.114537","DOIUrl":"10.1016/j.ejca.2024.114537","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 114537"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
100 (PB088): KRASmulti inhibitor BI 3706674 shows efficacy in KRAS-driven preclinical models of cancer that supports clinical testing in patients with tumors harboring KRASG12V mutations and KRAS wild-type amplifications. 100（PB088）：KRAS 多种抑制剂 BI 3706674 在 KRAS 驱动的癌症临床前模型中显示出疗效，支持对携带 KRASG12V 突变和 KRAS 野生型扩增的肿瘤患者进行临床试验。
IF 7.6 1区 医学
European Journal of Cancer Pub Date : 2024-10-01 DOI: 10.1016/j.ejca.2024.114624
A. Tedeschi, D.H. Peng, F. Schischlik-Siegl, O. Schaaf, D. Gerlach, F. Rocchetti, J. Popow, J. Broeker, T. Wunberg, A.S. Boghossian, M.G. Rees, M.M. Ronan, J.A. Roth, M. Williams, C. Vellano, J.R. Marszalek, T.P. Heffernan, M. Pearson, N. Kraut, R. Dorothea
{"title":"100 (PB088): KRASmulti inhibitor BI 3706674 shows efficacy in KRAS-driven preclinical models of cancer that supports clinical testing in patients with tumors harboring KRASG12V mutations and KRAS wild-type amplifications.","authors":"A. Tedeschi, D.H. Peng, F. Schischlik-Siegl, O. Schaaf, D. Gerlach, F. Rocchetti, J. Popow, J. Broeker, T. Wunberg, A.S. Boghossian, M.G. Rees, M.M. Ronan, J.A. Roth, M. Williams, C. Vellano, J.R. Marszalek, T.P. Heffernan, M. Pearson, N. Kraut, R. Dorothea","doi":"10.1016/j.ejca.2024.114624","DOIUrl":"10.1016/j.ejca.2024.114624","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 114624"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142526355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peer Review Policy for the European Journal of Cancer (EJC) 欧洲癌症杂志》（EJC）同行评审政策
IF 7.6 1区 医学
European Journal of Cancer Pub Date : 2024-10-01 DOI: 10.1016/j.ejca.2024.115026
{"title":"Peer Review Policy for the European Journal of Cancer (EJC)","authors":"","doi":"10.1016/j.ejca.2024.115026","DOIUrl":"10.1016/j.ejca.2024.115026","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 115026"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
93 (PB081): The T-BOX transcription factors TBX2 and TBX3 are molecular targets of piroctone olamine in the treatment of pancreatic ductal adenocarcinoma 93 (PB081)：T-BOX转录因子TBX2和TBX3是吡罗酮橄榄胺治疗胰腺导管腺癌的分子靶点
IF 7.6 1区 医学
European Journal of Cancer Pub Date : 2024-10-01 DOI: 10.1016/j.ejca.2024.114619
K. Serala, S. Mdletshe, J. Bai, A. Abrahams, S. Prince
{"title":"93 (PB081): The T-BOX transcription factors TBX2 and TBX3 are molecular targets of piroctone olamine in the treatment of pancreatic ductal adenocarcinoma","authors":"K. Serala, S. Mdletshe, J. Bai, A. Abrahams, S. Prince","doi":"10.1016/j.ejca.2024.114619","DOIUrl":"10.1016/j.ejca.2024.114619","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"211 ","pages":"Article 114619"},"PeriodicalIF":7.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142534681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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