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A Phase 1a/1b Trial in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma to Determine the Safety Profile, Pharmacology, and Maximum Tolerated Dose of ST-001, an Intravenous Fenretinide Phospholipid Suspension (12.5 mg/mL) 一项针对复发/难治性t细胞非霍奇金淋巴瘤的1a/1b期试验，以确定ST-001的安全性、药理学和最大耐受剂量，ST-001是一种静脉注射芬瑞啶脂混悬液（12.5 mg/mL）
IF 7.1 1区 医学
European Journal of Cancer Pub Date : 2025-10-01 DOI: 10.1016/j.ejca.2025.115879
Oleg E. Akilov, Auris O. Huen, Barbara Pro, Dipenkumar Modi, Ann F. Mohrbacher, Brad M. Haverkos, Aaron R. Mangold, Christiane Querfeld, Ryan A. Wilcox, Louis M. Scarmoutzos, Michael Burns, Earle T. Holsapple, Kenneth D. Massey, Ralph E. Parchment, Yamini Donekal, Ali Moiin
{"title":"A Phase 1a/1b Trial in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma to Determine the Safety Profile, Pharmacology, and Maximum Tolerated Dose of ST-001, an Intravenous Fenretinide Phospholipid Suspension (12.5 mg/mL)","authors":"Oleg E. Akilov, Auris O. Huen, Barbara Pro, Dipenkumar Modi, Ann F. Mohrbacher, Brad M. Haverkos, Aaron R. Mangold, Christiane Querfeld, Ryan A. Wilcox, Louis M. Scarmoutzos, Michael Burns, Earle T. Holsapple, Kenneth D. Massey, Ralph E. Parchment, Yamini Donekal, Ali Moiin","doi":"10.1016/j.ejca.2025.115879","DOIUrl":"10.1016/j.ejca.2025.115879","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"229 ","pages":""},"PeriodicalIF":7.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145289675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical synchronizers of circadian oscillations in jurkat T-cell leukemia jurkat t细胞白血病昼夜节律振荡的化学同步器
IF 7.1 1区 医学
European Journal of Cancer Pub Date : 2025-10-01 DOI: 10.1016/j.ejca.2025.115840
Marjan Motiei, Raed Abu-Dawud, Angela Relógio, Mathias Oymanns, Chalid Assaf
{"title":"Chemical synchronizers of circadian oscillations in jurkat T-cell leukemia","authors":"Marjan Motiei, Raed Abu-Dawud, Angela Relógio, Mathias Oymanns, Chalid Assaf","doi":"10.1016/j.ejca.2025.115840","DOIUrl":"10.1016/j.ejca.2025.115840","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"229 ","pages":""},"PeriodicalIF":7.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145289762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LIF Receptor Inhibitor EC359 Impairs Proliferation of Hut78, HH and Jurkat Cell Lines LIF受体抑制剂EC359损害hu78、HH和Jurkat细胞系的增殖
IF 7.1 1区 医学
European Journal of Cancer Pub Date : 2025-10-01 DOI: 10.1016/j.ejca.2025.115845
Raed Abu-Dawud, Marjan Motiei, Terkild B. Buus, Nils Ødum, Mathias Oymanns, Chalid Assaf
{"title":"LIF Receptor Inhibitor EC359 Impairs Proliferation of Hut78, HH and Jurkat Cell Lines","authors":"Raed Abu-Dawud, Marjan Motiei, Terkild B. Buus, Nils Ødum, Mathias Oymanns, Chalid Assaf","doi":"10.1016/j.ejca.2025.115845","DOIUrl":"10.1016/j.ejca.2025.115845","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"229 ","pages":""},"PeriodicalIF":7.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145289767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stage-specific changes in the spatial immune landscape of Mycosis Fungoides (MF) 蕈样真菌病（Mycosis Fungoides， MF）空间免疫景观的阶段性变化
IF 7.1 1区 医学
European Journal of Cancer Pub Date : 2025-10-01 DOI: 10.1016/j.ejca.2025.115824
Veerle A. Merkus, Marieke E. Ijsselsteijn, Marie S.N. Chevalier Florquin, Sanne de Haan, Vincent van Unen, Cornelis P. Tensen, Abdoel El Ghalbzouri, Anne M.R. Schrader, Ferenc A. Scheeren, Noel F.C.C. de Miranda, Maarten H. Vermeer, Koen D. Quint PhD
{"title":"Stage-specific changes in the spatial immune landscape of Mycosis Fungoides (MF)","authors":"Veerle A. Merkus, Marieke E. Ijsselsteijn, Marie S.N. Chevalier Florquin, Sanne de Haan, Vincent van Unen, Cornelis P. Tensen, Abdoel El Ghalbzouri, Anne M.R. Schrader, Ferenc A. Scheeren, Noel F.C.C. de Miranda, Maarten H. Vermeer, Koen D. Quint PhD","doi":"10.1016/j.ejca.2025.115824","DOIUrl":"10.1016/j.ejca.2025.115824","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"229 ","pages":""},"PeriodicalIF":7.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145289536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tracking Sézary Cells and Relapse: The Role of CD39 and CD73 in Mogamulizumab-Treated Patients 追踪ssamzary细胞和复发：CD39和CD73在mogamulizumab治疗患者中的作用
IF 7.1 1区 医学
European Journal of Cancer Pub Date : 2025-10-01 DOI: 10.1016/j.ejca.2025.115832
S. Marchisio, Y. Yakymiv, L. Lin, E. Ortolan, G. Roccuzzo, F.J. de Bie, A.J. van der Sluijs-Gelling, V. Pala, W.H. Zoutman, F.A. Scheeren, A. El Ghalbzouri, C.P. Tensen, M.H. Vermeer, A. Funaro, P. Quaglino
{"title":"Tracking Sézary Cells and Relapse: The Role of CD39 and CD73 in Mogamulizumab-Treated Patients","authors":"S. Marchisio, Y. Yakymiv, L. Lin, E. Ortolan, G. Roccuzzo, F.J. de Bie, A.J. van der Sluijs-Gelling, V. Pala, W.H. Zoutman, F.A. Scheeren, A. El Ghalbzouri, C.P. Tensen, M.H. Vermeer, A. Funaro, P. Quaglino","doi":"10.1016/j.ejca.2025.115832","DOIUrl":"10.1016/j.ejca.2025.115832","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"229 ","pages":""},"PeriodicalIF":7.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145289632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Copyright Page 版权页
IF 7.1 1区 医学
European Journal of Cancer Pub Date : 2025-10-01 DOI: 10.1016/j.ejca.2025.116002
{"title":"Copyright Page","authors":"","doi":"10.1016/j.ejca.2025.116002","DOIUrl":"10.1016/j.ejca.2025.116002","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"229 ","pages":""},"PeriodicalIF":7.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145289640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dynamic expansion of CD39high regulatory B cells during disease progression in Sézary Syndrome ssamzary综合征疾病进展过程中cd39高调节性B细胞的动态扩增
IF 7.1 1区 医学
European Journal of Cancer Pub Date : 2025-10-01 DOI: 10.1016/j.ejca.2025.115816
Yuliya Yakymiv, Gabriele Roccuzzo, Sara Marchisio, Liyun Lin, Erika Ortolan, Simone Ribero, Renata Ponti, Valentina Pala, Yun Tsan Chang, Pacome Prompsy, Christoph Iselin, Yi Chien Tsai, Emmanuella Guenova, Ada Funaro, Pietro Quaglino
{"title":"Dynamic expansion of CD39high regulatory B cells during disease progression in Sézary Syndrome","authors":"Yuliya Yakymiv, Gabriele Roccuzzo, Sara Marchisio, Liyun Lin, Erika Ortolan, Simone Ribero, Renata Ponti, Valentina Pala, Yun Tsan Chang, Pacome Prompsy, Christoph Iselin, Yi Chien Tsai, Emmanuella Guenova, Ada Funaro, Pietro Quaglino","doi":"10.1016/j.ejca.2025.115816","DOIUrl":"10.1016/j.ejca.2025.115816","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"229 ","pages":""},"PeriodicalIF":7.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145289650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-World Treatment Patterns and Outcomes in Cutaneous T-Cell Lymphoma (CTCL) Patients Treated with Extracorporeal Photopheresis (ECP) Combined Therapy – A Chart Review Study Protocol 皮肤t细胞淋巴瘤（CTCL）患者接受体外光诱导（ECP）联合治疗的现实世界治疗模式和结果-图表回顾研究方案
IF 7.1 1区 医学
European Journal of Cancer Pub Date : 2025-10-01 DOI: 10.1016/j.ejca.2025.115881
Ling-Hsiang Chuang, Oscar Mesa, Laurence Covassin, Violetta Stone, Sneha Kelkar, Michael Girardi
{"title":"Real-World Treatment Patterns and Outcomes in Cutaneous T-Cell Lymphoma (CTCL) Patients Treated with Extracorporeal Photopheresis (ECP) Combined Therapy – A Chart Review Study Protocol","authors":"Ling-Hsiang Chuang, Oscar Mesa, Laurence Covassin, Violetta Stone, Sneha Kelkar, Michael Girardi","doi":"10.1016/j.ejca.2025.115881","DOIUrl":"10.1016/j.ejca.2025.115881","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"229 ","pages":""},"PeriodicalIF":7.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145289677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detection of blood involvement and marker expression in cutaneous T-cell lymphoma using FACS-based analysis of individual TCR Vβ families 基于facs的个体TCR Vβ家族分析检测皮肤t细胞淋巴瘤的血液浸润和标志物表达
IF 7.1 1区 医学
European Journal of Cancer Pub Date : 2025-10-01 DOI: 10.1016/j.ejca.2025.115886
Johannes Woltsche, Andrea Teufelberger, Pablo Vieyra-Garcia, Isabella Perchthaler, Hanna Schratter, Regina Fink-Puches, Alexandra Gruber-Wackernagel, Angelika Hofer, Franz Legat, Lorenzo Cerroni, Peter Wolf
{"title":"Detection of blood involvement and marker expression in cutaneous T-cell lymphoma using FACS-based analysis of individual TCR Vβ families","authors":"Johannes Woltsche, Andrea Teufelberger, Pablo Vieyra-Garcia, Isabella Perchthaler, Hanna Schratter, Regina Fink-Puches, Alexandra Gruber-Wackernagel, Angelika Hofer, Franz Legat, Lorenzo Cerroni, Peter Wolf","doi":"10.1016/j.ejca.2025.115886","DOIUrl":"10.1016/j.ejca.2025.115886","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"229 ","pages":""},"PeriodicalIF":7.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145289682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study of interactions between Sézary Syndrome derived patient’s cells and monocytes/macrophages ssamzary综合征患者细胞与单核/巨噬细胞相互作用的研究
IF 7.1 1区 医学
European Journal of Cancer Pub Date : 2025-10-01 DOI: 10.1016/j.ejca.2025.115837
Amandine Roussel, Thibaut Blonde, Martina Prochazkova-Carlotti, Camille Morize, Rémi Peanne, Thomas Paz Del Socorro, Anne Pham-Ledard, Jean-Philippe Merlio, Marie Beylot-Barry, Laurence Bresson-Bepoldin, Sandrine Poglio
{"title":"Study of interactions between Sézary Syndrome derived patient’s cells and monocytes/macrophages","authors":"Amandine Roussel, Thibaut Blonde, Martina Prochazkova-Carlotti, Camille Morize, Rémi Peanne, Thomas Paz Del Socorro, Anne Pham-Ledard, Jean-Philippe Merlio, Marie Beylot-Barry, Laurence Bresson-Bepoldin, Sandrine Poglio","doi":"10.1016/j.ejca.2025.115837","DOIUrl":"10.1016/j.ejca.2025.115837","url":null,"abstract":"","PeriodicalId":11980,"journal":{"name":"European Journal of Cancer","volume":"229 ","pages":""},"PeriodicalIF":7.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145289690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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