European Journal of Clinical Microbiology最新文献_第8页

Group B streptococcal endocarditis in Down's syndrome. 唐氏综合征B组链球菌性心内膜炎。

European Journal of Clinical Microbiology Pub Date : 1987-08-01 DOI: 10.1007/BF02013103

J Billheden, S Schliamser, P Eriksson, R S Norrby

引用次数: 0

Evaluation of an enzyme immunoassay for detection of herpes simplex virus antigen in genital lesions. 一种检测生殖器病变中单纯疱疹病毒抗原的酶免疫分析法的评价。

European Journal of Clinical Microbiology Pub Date : 1987-08-01 DOI: 10.1007/BF02013096

J van Ulsen, A M Dumas, J H Wagenvoort, A van Zuuren, T van Joost, E Stolz

{"title":"Evaluation of an enzyme immunoassay for detection of herpes simplex virus antigen in genital lesions.","authors":"J van Ulsen, A M Dumas, J H Wagenvoort, A van Zuuren, T van Joost, E Stolz","doi":"10.1007/BF02013096","DOIUrl":"https://doi.org/10.1007/BF02013096","url":null,"abstract":"To evaluate a non-marketed research prototype of a solid-phase enzyme immunoassay for detection of herpes simplex virus in genital lesions, 154 clinical specimens were collected from 127 men and 27 women with symptoms suggestive of herpes simplex virus infection (erythema, vesicles, ulcers and crustae). The samples were tested using the assay and cultures on four monolayers of human embryonic lung fibroblasts and Vero cells. When the culture was used as reference method, sensitivity was 76.9% and specificity 100% (prevalence 42.4%). Comparison of results by patient group showed that sensitivity was highest in material from patients with vesicles and ulcers. The highest sensitivity was obtained in specimens which developed a cytopathological effect within 48 h and in specimens with three or four positive cell cultures. These findings suggest that the assay is more successful in specimens with high virus titres. The enzyme immunoassay was found to be a rapid, moderately sensitive, highly specific test for detection of herpes simplex virus from genital lesions, but the usefulness of the assay is limited and culture methods should be preferred.","PeriodicalId":11958,"journal":{"name":"European Journal of Clinical Microbiology","volume":"6 4","pages":"410-3"},"PeriodicalIF":0.0,"publicationDate":"1987-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02013096","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13960028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vivo and in vitro activity of roxithromycin against Toxoplasma gondii in mice. 罗红霉素对小鼠刚地弓形虫体内外活性的研究。

European Journal of Clinical Microbiology Pub Date : 1987-08-01 DOI: 10.1007/BF02013115

B J Luft

引用次数: 8

In vitro activity of the two new oral cephalosporins RO 15-8074 and RO 19-5247. 两种新型口服头孢菌素RO 15-8074和RO 19-5247的体外活性。

European Journal of Clinical Microbiology Pub Date : 1987-08-01 DOI: 10.1007/BF02013119

E Stobberingh, A W Houben, C P van Boven

引用次数: 2

Bacteria isolated from skin and soft tissue lesions. 从皮肤和软组织病变中分离出的细菌。

European Journal of Clinical Microbiology Pub Date : 1987-08-01 DOI: 10.1007/BF02013100

S Kontiainen, E Rinne

引用次数: 17

World-wide development of antibiotic resistance in pneumococci. 世界范围内肺炎球菌抗生素耐药性的发展。

European Journal of Clinical Microbiology Pub Date : 1987-08-01 DOI: 10.1007/BF02013089

P C Appelbaum

{"title":"World-wide development of antibiotic resistance in pneumococci.","authors":"P C Appelbaum","doi":"10.1007/BF02013089","DOIUrl":"https://doi.org/10.1007/BF02013089","url":null,"abstract":"Antibiotic-resistant pneumococci, especially penicillin-resistant strains, are being increasingly isolated. Pneumococci with intermediate penicillin-resistance (MIC 0.1-1.0 micrograms/ml) have been reported from many parts of the world over the past two decades, and highly resistant strains (penicillin MICs greater than or equal to 2 micrograms/ml) have also appeared. Infection may be acquired in the hospital or community, and nosocomial outbreaks may occur which require control measures to limit organism spread. Most infections occur in children with diminished host responses. Disease caused by pneumococci with intermediate penicillin-resistance may be treated with high doses of penicillin, but disease caused by highly resistant strains, especially meningitis, may require alternative therapy. Pneumococci resistant to sulfonamides, tetracyclines, erythromycin, lincomycin, clindamycin, chloramphenicol, aminoglycosides and rifampin have also appeared. Strains resistant to all the above-mentioned agents, including all beta-lactam antibiotics tested, have been reported from South Africa and Spain. Alternative therapy for resistant strains may include vancomycin, cefotaxime, cefoperazone, ceftriaxone and imipenem. Pneumococci isolated from sites suggestive of infection, especially blood and cerebrospinal fluid, should be routinely tested for penicillin-susceptibility.","PeriodicalId":11958,"journal":{"name":"European Journal of Clinical Microbiology","volume":"6 4","pages":"367-77"},"PeriodicalIF":0.0,"publicationDate":"1987-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02013089","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14440319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 59

Ability of newer beta-lactam antibiotics to induce beta-lactamase production in Enterobacter cloacae. 较新的-内酰胺类抗生素诱导阴沟肠杆菌产生-内酰胺酶的能力。

European Journal of Clinical Microbiology Pub Date : 1987-08-01 DOI: 10.1007/BF02013109

R L Then

引用次数: 17

Streptococcal protein G: a sensitive tool for detection of antibodies to human immunodeficiency virus proteins in Western blot analysis. 链球菌蛋白G:一种在Western blot分析中检测人类免疫缺陷病毒蛋白抗体的敏感工具。

European Journal of Clinical Microbiology Pub Date : 1987-08-01 DOI: 10.1007/BF02013104

L Björck, J Blomberg

引用次数: 7

In vitro susceptibility to aminoglycoside antibiotics in blood and urine isolates consecutively collected in twenty-nine European laboratories. European Study Group on Antibiotic Resistance. 对欧洲29个实验室连续采集的血、尿分离株氨基糖苷类抗生素进行体外药敏试验。欧洲抗生素耐药性研究小组。

European Journal of Clinical Microbiology Pub Date : 1987-08-01 DOI: 10.1007/BF02013090

引用次数: 5

Clinical consequences of development of resistance to third generation cephalosporins. 第三代头孢菌素耐药性发展的临床后果。

European Journal of Clinical Microbiology Pub Date : 1987-08-01 DOI: 10.1007/BF02013108

F Follath, E Costa, A Thommen, R Frei, A Burdeska, J Meyer

{"title":"Clinical consequences of development of resistance to third generation cephalosporins.","authors":"F Follath, E Costa, A Thommen, R Frei, A Burdeska, J Meyer","doi":"10.1007/BF02013108","DOIUrl":"https://doi.org/10.1007/BF02013108","url":null,"abstract":"Eighteen patients are described in whom initially sensitive microorganisms were replaced by resistant isolates during administration of ceftriaxone (n = 8), cefoperazone (n = 5), moxalactam (n = 4), cefotaxime (n = 2) or ceftazidime (n = 1), despite combination with aminoglycosides. All patients had documented gram-negative infections; in 12 patients underlying haematological diseases were present. Resistant strains of Enterobacter cloacae (14), Serratia marcescens (4), Klebsiella oxytoca (3), Pseudomonas aeruginosa (2) and Citrobacter freundii (2) emerged within 2 to 19 (mean 9) days after the beginning of treatment. In 12 patients relapse or secondary infections occurred. Seven of the patients with haematological disorders died. Resistance development was seen in 8 of 29 patients on ceftriaxone and 4 of 10 patients on moxalactam during prospective evaluations; the other drugs were used sporadically. Thus, selection of resistant bacteria is relatively frequent and may have serious clinical consequences in patients with impaired host-defense mechanisms.","PeriodicalId":11958,"journal":{"name":"European Journal of Clinical Microbiology","volume":"6 4","pages":"446-50"},"PeriodicalIF":0.0,"publicationDate":"1987-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02013108","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14248854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15