European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation最新文献

{"title":"Smelly science.","authors":"L. Ovesen","doi":"10.1097/00008469-200202000-00010","DOIUrl":"https://doi.org/10.1097/00008469-200202000-00010","url":null,"abstract":"smelly science What to say and what to do when mostly your friends love reading? Are you the one that don't have such hobby? So, it's important for you to start having that hobby. You know, reading is not the force. We're sure that reading will lead you to join in better concept of life. Reading will be a positive activity to do every time. And do you know our friends become fans of smelly science as the best book to read? Yeah, it's neither an obligation nor order. It is the referred book that will not make you feel disappointed.","PeriodicalId":11950,"journal":{"name":"European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88856206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing strategies for the detection of gene-nutrient interactions in the aetiology of colorectal neoplasia: discussion and conclusions from the ECP consensus-forming workshop. Brussels, 25-26 September 2000.","authors":"","doi":"10.1097/00008469-200202000-00017","DOIUrl":"https://doi.org/10.1097/00008469-200202000-00017","url":null,"abstract":"","PeriodicalId":11950,"journal":{"name":"European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88020046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Christmas in science.","authors":"L. Ovesen","doi":"10.1097/00008469-200112000-00009","DOIUrl":"https://doi.org/10.1097/00008469-200112000-00009","url":null,"abstract":"","PeriodicalId":11950,"journal":{"name":"European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87251844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carditis, intestinal metaplasia and adenocarcinoma of oesophagogastric junction.","authors":"M. Conio, R. Filiberti, S. Blanchi, A. Giacosa","doi":"10.1097/00008469-200112000-00002","DOIUrl":"https://doi.org/10.1097/00008469-200112000-00002","url":null,"abstract":"Barrett's oesophagus is a precancerous condition in which the normal squamous epithelium is replaced by intestinal metaplasia (IM). IM can then progress through increasingly severe dysplasia to oesophageal adenocarcinoma (EAC). In the gastric cardia the normal gastric mucosa, when inflamed (carditis), can be replaced by IM and can then progress to gastric adenocarcinoma (GAC). The same histopathological sequence can take place on either side of the oesophagogastric junction. Since the location of that junction can be uncertain this can result in confused diagnosis between EAC and GAC. In this review, the diagnostic criteria, incidence and risk factors for Barrett's oesophagus and carditis are discussed, together with the factors determining the risk of progression to adenocarcinoma of the oesophagus or cardia. The risk factors include familial/genetic, environmental and dietary characteristics. Finally, these risk factors are discussed within the context of cancer prevention.","PeriodicalId":11950,"journal":{"name":"European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89472638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast cancer and PCBs: true or false association?","authors":"M. Allam, R. A. Lucena","doi":"10.1097/00008469-200112000-00010","DOIUrl":"https://doi.org/10.1097/00008469-200112000-00010","url":null,"abstract":"The issue of a possible association between polyŽ . chlorinated biphenyls PCBs and increased risk of breast cancer is important. Numerous epidemiological studies have examined the relationship, but the Ž results are not consistent Moysich et al., 1998; Dorgan et al., 1999; Aronson et al., 2000; Stellman et al., 2000; Zheng et al., 2000; Laden et al., 2001a; . Lucena et al., 2001 . Meanwhile, experimental studies had demonstrated that some PCBs have oestrogenic activity and enhance proliferation of breast Ž tumour cells Safe, 1992; Jansen et al., 1993; Wolff . and Toniolo, 1995 . Ž . Recently, Laden et al. 2001b reported no relationship based on results of pooled analysis of five Ž US studies. Total PCBs, and only few PCB n-118, . 138, 153 and 180 were analysed in serum. Meanwhile, it is feasible to use blood sera to obtain and analyse PCBs. Adipose tissue PCB levels have been regarded as a preferred indicator of human exposure. Levels in breast adipose tissue are known to be higher and more representative of the cumulative internal exposure at the target site for breast cancer ŽArchibeque-Engle et al., 1997; Angulo et al., 1999; . Lopez-Carrillo et al., 1999 . Archibeque-Engle et al. Ž . 1997 did not find a significant relationship between serum concentrations and tissue residues for 15 compounds analysed. Based on the lack of correlation between breast adipose tissue and serum, as well as an absence of some compound residues in serum, the authors emphasized that adipose tissue should be analysed in addition to serum to fully understand the relationship between organochlorine compounds and breast cancer. In adipose tissue a positive association with indiŽ vidual PCBs has been demonstrated Aronson et al., . 2000; Stellman et al., 2000; Lucena et al., 2001 . However, in a hospital-based case control study, Ž . Zheng et al. 2000 , analysing nine PCBs in breast fat, reached the conclusion that PCBs are not a risk factor for breast cancer. Breast cancer risk associated with PCBs varies according to specific PCB Ž . congeners Safe, 1992 , and Zheng et al. mentioned a possible carcinogenic effect based on the total level of PCBs after failure to find positive association with individual congeners. We think that every PCB could have a different effect on human cells, and some have oestrogenic activity while others have anti-oestrogenic activity. Therefore, the conclusions of Zheng et al. are not justified, especially considering that among all PCBs evaluated the only potentially oestrogenic PCB was PCB n-187. Furthermore, Ž the study included fewer controls than cases 186 . versus 304 , making the possibility of demonstrating such risk, if present, more difficult. In a similar hospital-based case control study, we measured the levels of eleven PCB congeners in breast fat of all women subjected to surgical interference because of breast lumps, in our university Ž hospital over a 10-month period Lucena et al., . 2001 . A highly positive association was fou","PeriodicalId":11950,"journal":{"name":"European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81210427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Food additives, contaminants and cancer.","authors":"M. Hill","doi":"10.1097/00008469-200110000-00001","DOIUrl":"https://doi.org/10.1097/00008469-200110000-00001","url":null,"abstract":"","PeriodicalId":11950,"journal":{"name":"European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90970729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"International conference on dietary factors: cancer causes and prevention, Vienna, 14-17 February 2001.","authors":"F. Schweinsberg","doi":"10.1097/00008469-200108000-00012","DOIUrl":"https://doi.org/10.1097/00008469-200108000-00012","url":null,"abstract":"Until recently, phytoprotectants were considered almost exclusively with regard to their toxicological potency. In table 4 of Principles and Methods of Ž . Toxicology Hayes, 1994 , entitled ‘Certain carcinogens and mutagens in the diet’, the following compounds are listed, in addition to mycotoxins, alcohol and cooked food carcinogens: allylisothiocyanate, caffeine and theobromine, flavonoids, d-limonene and polyphenols. These are phytoprotectants, the anticarcinogenic actions of which are increasingly coming under discussion. The problems in determining the risk of cancer that is connected with diet were illustrated in 1981 by Doll and Peto. Using all available epidemiological data it was shown to be in the range of 10 70%. The impact of this paradigm on health was discussed at the Vienna Conference under an impressing international audience. The culinary uses of protective compounds in the diet were applied by the Austrian master cook, Reinhold Gerer, in a truly masterly and delicate benefit dinner in favour of the Institute of Cancer Research, University of Vienna. In this way it was demonstrated convincingly how good healthy food can taste. The director of the Institute of Cancer Research, Professor Dr SchulteHermann and all participants of the meeting finally congratulated Professor Dr Knasmuller and his cö workers for the excellent organization and quality of the conference. An attempt will now be made to summarize and comment on selected contributions to the meeting.","PeriodicalId":11950,"journal":{"name":"European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72843644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clothes make the man.","authors":"L. Ovesen","doi":"10.1097/00008469-200108000-00015","DOIUrl":"https://doi.org/10.1097/00008469-200108000-00015","url":null,"abstract":"Feel lonely? What about reading books? Book is one of the greatest friends to accompany while in your lonely time. When you have no friends and activities somewhere and sometimes, reading book can be a great choice. This is not only for spending the time, it will increase the knowledge. Of course the b=benefits to take will relate to what kind of book that you are reading. And now, we will concern you to try reading clothes make the man as one of the reading material to finish quickly.","PeriodicalId":11950,"journal":{"name":"European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84901772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decreasing incidence of all histological subtypes of oesophagus cancer in Tuscany, Italy.","authors":"E. Crocetti, G. Miccinesi, E. Paci","doi":"10.1097/00008469-200108000-00013","DOIUrl":"https://doi.org/10.1097/00008469-200108000-00013","url":null,"abstract":"In a paper recently published in this journal, Levi et Ž . al. 2001 analysed the rise in incidence of oesophageal adenocarcinomas observed in the Registry of Vaud, Switzerland. During the long peŽ . riod examined 1976 1998 there was an overall decrease in the incidence of oesophagus cancer due to the balance between the decrease in squamous Ž cell carcinomas about 66% of all oesophagus can. cers in Vaud in 1995 1998 , an increase for adenoŽ . carcinomas about 22% and a decrease for cases Ž . with other and unspecified morphology about 12% . The contrasting trends between squamous and adenocarcinomas may be due, according to the authors, to the different trends of morphology-specific risk factors. The evidenced increase in the rates for adenocarcinomas of the oesophagus agreed with similar results in other but not all 10 European Ž . countries recently analysed Botterweck et al., 2000 . We want to contribute with further descriptive Ž . data from the Tuscany Cancer Registry RTT . The RTT is a population-based cancer registry active in the provinces of Florence and Prato, central Italy Ž . since 1984 Buiatti et al., 1997 . The age-adjusted incidence rates for oesophagus cancer in the RTT area around the 1990s were 3.7 per 100 000 among Ž . males and 0.9 among females Parkin et al., 1997 . Ž These rates were on the Italian average range . 1.0 9.7 among males and 0.4 1.5 among females Ž but lower than those from Vaud 9.5 for males and . 2.0 for females, respectively and from most other Ž . European countries Parkin et al., 1997 . Ž During 1985 1997, 613 oesophagus cancers 427, . 69.7% males and 186, 30.3% females were diagŽ nosed among the resident population about . 1 180 000 at the 1991 census . Incidence rates from Ž 1985 to 1997 directly standardized to the European . Ž population , percentage change PC, as the percentage difference of the mean of the rates of the last 2 . years minus that of the first 2 years considered and the expected annual percentage change in a logŽ . linear model EAPC were computed with the Ž . SEER Stat software seerstat@ims.nci.nih.gov . The overall incidence trend was downward with a PC of Ž 32.4%, similar in both sexes PC 35.4% among . males and 31.4% among females . There was an Ž overall statistically significant EAPC of 3.5% 95% . CI 6.3 0.7 also significant among males Ž . EAPC 4.3, 95% CI 7.9 0.5 but not among Ž . females EAPC 3.0, 95% CI 6.1 0.2 probably because of the relatively small sample. Ž . Following Levi et al. 2001 , we analysed the following morphological categories: squamous cell carŽ . cinoma ICD-O M 8050 8082 , adenocarcinoma Ž . 8140 8573 and other and unspecified cancers. In our data set there were 299 squamous cell carcinoŽ . Ž . mas 48.8% , 71 adenocarcinomas 11.6% and 243 Ž . 39.6% other and unspecified cases. The proportion of microscopic confirmations was rather low although it had improved over time, being only 53% in 1985 and reaching 70% in 1997. The time trends were similar and decreasing ","PeriodicalId":11950,"journal":{"name":"European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74445196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral and pharyngeal cancer: lack of prevention and early detection by health care providers.","authors":"M. Mignogna, S. Fedele, L. Lo Russo, E. Ruoppo, L. Lo Muzio","doi":"10.1097/00008469-200108000-00014","DOIUrl":"https://doi.org/10.1097/00008469-200108000-00014","url":null,"abstract":"Worldwide, approximately 8% of all cancers in men occur in the mouth and pharynx, with a correspondŽ ing estimate for women being 4% Pindborg et al., . 1997 amounting to around 250 000 new cases in men each year and 120 000 in women. More than 90% of all oral and pharyngeal cancers occur in individuals older than 45, although there is evidence of an increasing incidence of tongue cancer in Ž . younger age groups La Vecchia et al., 1997 . Major risk factors include use of tobacco products, heavy alcohol consumption and exposure to the sun for lip cancer. According to late stages diagnosis, the 5-year survival rate is only 52%. In recent decades, in spite of advances in detection and treatment of many other malignancies, this rate has remained disapŽ pointingly low and relatively constant Greenlee et . al., 2000 . Treatment often produces dysfunction and distortions in speech, mastication, swallowing, dental health and even in the ability to interact socially. Thus, it must be considered among the most debilitating and disfiguring of all cancers. As is the case with most other malignancies, early detection of malignant and premalignant lesions and reduction of risk factors can produce a great improvement in the prognosis. Therefore, annual mouth examinations in people over 40 and the cessation of alcohol and tobacco consumption are the imperative goals of every health programme against Ž oral cancer American Cancer Society, 1992; British . Dental Association, 1998 . As many authors suggest ŽDanish Dental Association, 1990; Horowitz et al., . 1996 , dentists share an important role in secondary prevention of oral cancer. In fact, dental recalls are considered to be a great opportunity for the detection of asymptomatic early malignant neoplasm, for the differentiation of benign from precancerous conditions and for the undertaking of biopsies or referrals of patients to oral surgeons or oral medicine ENT specialists. This opportunistic screening of the oral mucosa, particularly in high-risk individuals, consists of soft tissue examination, which could be carried out as part of a 5-minute dental inspection. It is thought to decrease morbidity and mortality in the same way as other screening procedures, such as those used in respect of breast and cervical carcinomas. In the last few years other scientists have emphasized a more important role for dental practitioners, suggesting they should be responsible also for primary prevention, giving advice on smoking cessation, alcohol moderation and sun protection Ž . Macgregor, 1996; Johnson, 1997 . In spite of all these guidelines, in the past few decades no remarkable progress has occurred in improving the earlier diagnosis and prognosis of oral Ž . cancer Greenlee et al., 2000 . Most oral and pharyngeal malignancies are detected at a late stage and smoking and drinking habits still remain the major aetiological factors in the development of oral cancer, synchronous and metachronous second primary tumours of","PeriodicalId":11950,"journal":{"name":"European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2001-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78978127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}