The Journal of Pediatric Academy最新文献

{"title":"The Association Between Platelet Mass Index and Mechanical Ventilation in Pediatric Surgery Cases","authors":"M. Silahli","doi":"10.51271/jpea-2021-0124","DOIUrl":"https://doi.org/10.51271/jpea-2021-0124","url":null,"abstract":"Platelet mass index (PMI) is an indicator of platelet functionality. This study aimed to examine the relationship between PMI and mechanical ventilation need in infants less than 1 year of age who underwent gastrointestinal system surgery. We retrospectively reviewed the medical records of cases that underwent gastrointestinal surgery in the last 10 years (2010-2020) at Baskent University Konya Hospital. Demographic data, indications for surgery, age at surgery, preoperative blood tests, hospitalization times, discharge status, mechanical ventilation need and duration, sepsis, accompanying anomalies, recurrent surgery requirements were collected from patient records. The study group (n: 143) was divided into 2 groups as the need for mechanical ventilation (MV; n: 73) and the group that did not need mechanical ventilation (n-MV; n: 70). Data were analyzed with SPSS version 25. PMI was significantly lower in the MV group (1999 Vs 2798, p< .001). 65% of the cases were newborns. Mean gestational age was 34.5 ±4 weeks, and birth weight was 2100 ± 820 g. Most of the cases that need surgical intervention consist of small bowel atresia, esophageal atresia, surgeries due to necrotizing enterocolitis, and anal atresia. Ileus was present in 54% of the patients. The recurrent surgery requirement was 34%. The frequency of accompanying cardiac anomalies was 30.6%, and the rate of proven sepsis was 38.3%. Preoperative 2163 PMI value can discriminate not needing MV with 72% sensitivity and 69% specificity (AUC: .699, p<.001). When the basic characteristics of the groups were evaluated, 83% of the patients who underwent MV were in the newborn group. The birth weight, gestational age, hospital duration, oxygen exposure, culture-positive sepsis rates, total parenteral nutrition (TPN) rates, and duration were found to be significantly higher in patients who underwent MV. While there was no difference in the number of white blood cells in the preoperative blood analysis, the neutrophil-lymphocyte (N-L) ratio, platelet number, albumin values were significantly lower and CRP values were significantly higher in the MV group. There was no difference in the platelet –lymphocyte (PL) ratio. High PMI values can be used as a parameter to discriminate the need for mechanical ventilation","PeriodicalId":118905,"journal":{"name":"The Journal of Pediatric Academy","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115755816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bladder Papilloma As A Rare Cause Of Urogenital Bleeding In A Prepubertal Girl","authors":"S. Kurtoğlu, M. Armut, F. Öztürk","doi":"10.51271/jpea-2021-0127","DOIUrl":"https://doi.org/10.51271/jpea-2021-0127","url":null,"abstract":"There are different causes of urogenital bleeding in prepubertal girls. These include vulvovaginitis, urinary infections, urethral prolapse, urethral caruncle, vaginal foreign bodies, hormonal causes, tumors, posterior labial fusion, lichen sclerosis. Among the tumors, rhabdomyosarcoma and papilloma are prominent. In this article, a case of urogenital hemorrhage due to papilloma located at the base of the bladder was presented and the relevant literature was reviewed","PeriodicalId":118905,"journal":{"name":"The Journal of Pediatric Academy","volume":"216 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122367474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Common Viral Infections In Children After Kidney Transplantation","authors":"T. Chaiyapak","doi":"10.51271/jpea-2021-0125","DOIUrl":"https://doi.org/10.51271/jpea-2021-0125","url":null,"abstract":"Viral infection is a common complication among pediatric kidney transplant recipients, causing significant morbidity and mortality. Sources of viral infection in pediatric transplant recipients include donor allografts, blood products, and latent virus reactivation. Major risks of viral infection include kidney donor-derived, nosocomial and community-acquired infections as well as the immunosuppressive status of recipients. Clinical presentations are variable, ranging from no symptoms to severe disease. Preventive strategies such as immunization and pretransplant-specific viral screening in both donors and recipients are performed before kidney transplantation to identify high-risk recipients. Posttransplant prophylactic strategies include universal prophylaxis and preemptive therapy. Universal antiviral prophylaxis is required for high-risk cytomegalovirus (CMV)-mismatch pediatric recipients. Preemptive therapy requires the administration of sensitive viral surveillance tests to detect subclinical viral infections to optimize individualized immunosuppressive drugs and initiate antiviral therapy. This review summarizes current knowledge regarding common viral infections in children after kidney transplantation, including CMV, BK polyomavirus, Epstein-Barr virus (EBV), and coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).","PeriodicalId":118905,"journal":{"name":"The Journal of Pediatric Academy","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130308190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipid Emulsion Treatment in Tricyclic Antidepressant Poisoning in Children: An Observational Cohort Study","authors":"Esra Türe, F. Akın, A. Yazar, A. Kılıç","doi":"10.51271/jpea-2021-0113","DOIUrl":"https://doi.org/10.51271/jpea-2021-0113","url":null,"abstract":"Tricyclic antidepressant (TCA) poisonings are among the most common childhood poisonings because of being cheap and readily available. In this manuscript, we aimed to share our experience with Intravenous lipid emulsions (ILE) treatment in addition to basic treatment steps and discussion of effectiveness of treatment in cases of poisoning caused by high-dose TCA intake. From the patients under 18 years of age who admitted to Pediatric Emergency Department due to drug intoxication between January 2014 and December 2019; those who had history of exposure to TCAs were included in our study. In conclusion of examination of six-year patient records, it was determined that there were a total of 619 intoxication cases and 108 (17.4%) of these were TCA poisoning. 21 (19.4%) patients who had hypotension, tachycardia and ECG changes which were refractory to all basic treatment steps were administered ILE. After ILE treatment, a marked improvement was observed in patients’ clinical and ECG findings, as well as vital signs. Early administration of ILE treatment in emergency departments for cases with hypotension, conduction disorder, dysrhythmia or widened QRS which are refractory to sodium bicarbonate is thought to prevent potential cardiovascular complications.","PeriodicalId":118905,"journal":{"name":"The Journal of Pediatric Academy","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128370182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Staphylococcal Pyomyositis Within Initial Course of Juvenile Dermatomyositis Patient","authors":"A. Paç Kısaarslan, H. Nalcacioglu, Taylan Çelik, G. Koç","doi":"10.51271/jpea-2021-0111","DOIUrl":"https://doi.org/10.51271/jpea-2021-0111","url":null,"abstract":"Infectious complications are increasingly reported in patients with connective tissue diseases. These complications are both related to using immunosuppressive drugs and organ dysfunctions caused by diseases. Pyomyositis is a pyogenic infection of skeletal muscle associated with immunocompromised conditions, especially human immunodeficiency virus (HIV) infection, diabetes mellitus, malignancy, immunosuppressive drugs, and rheumatic diseases. We presented a patient with juvenile dermatomyositis complicated by staphylococcal pyomyositis initial disease course. The patient did not respond to drainage and appropriate antibiotic therapy. Abscess formation successfully regressed with IVIG. Muscle inflammation and corticosteroids are possible predisposing factors for pyomyositis.","PeriodicalId":118905,"journal":{"name":"The Journal of Pediatric Academy","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124632487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare Autoinflammatory Diseases: A Single Center Experience of 47 Patients","authors":"Sema Nur Taşkın, A. Paç Kısaarslan, Sümeyra Özdemir Çiçek, Nihal Şahin, Şeyda Doğantan, M. Poyrazoğlu, R. Düşünsel","doi":"10.51271/jpea-2021-0110","DOIUrl":"https://doi.org/10.51271/jpea-2021-0110","url":null,"abstract":"Autoinflammatory diseases include a group disease characterized by recurrent systemic inflammatory attacks due to failure in the regulation of the innate immune system. The beginning time of autoinflammatory disease are the most commonly in childhood. Autoinflammatory disease which having different clinical forms are rare, therefore diagnosis is often delayed. To determine the clinical, laboratory and radiological characteristics of children with rare autoinflammatory diseases and in which patients to consider autoinflammatory disease. Forty seven patients diagnosed with rare autoinflammatory diseases between 2010 and 2020 were analyzed retrospectively. Demographic characteristics, clinical courses, laboratory and imaging findings of the patients were recorded. Forty-seven with rare autoinflammatory patients evaluated. Twenty-three patients had Chronic Nonbacterial Osteomyelitis (CNO), seven patients had Mevalonate Kinase Deficiency (MKD), six patients had Blau Syndrome / Early-Onset Sarcoidosis (BS/EOS) Syndrome, three patients had Cryopyrin-associated periodic fever syndrome (CAPS), three patients had Autoinflammatory Vasculitis, one patient had Sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay (SIFD) syndrome, one patient had Neonatal Onset Pancytopenia, Autoinflammation, Rash and Episodic HLH (NOARCH) syndrome. Three of our patients were being followed up with a diagnosis of undiferantiated systemic autoinflammatory disease (uSAID).Autoinflammatory diseases may have different presentations. Steril and recurrent inflammation should be warning clinicians.","PeriodicalId":118905,"journal":{"name":"The Journal of Pediatric Academy","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132637909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hereditary Red Blood Cell Enzymopathies","authors":"T. Aksu","doi":"10.51271/jpea-2021-0120","DOIUrl":"https://doi.org/10.51271/jpea-2021-0120","url":null,"abstract":"Red cell metabolic disturbances result in hemolysis, which leads to a significant shortening of the erythrocyte life span. The most common enzyme deficiencies are glucose 6-phosphate dehydrogenase (G6PD) in the antioxidant pathway, pyruvate kinase in the anaerobic glycolysis pathway, and pyrimidine 5’ nucleotidase (P5’N) in the nucleotide metabolism. While the X chromosome inherits G6PD and phosphoglycerate kinase deficiencies, other enzymopathies show autosomal recessive inheritance. Although the causes of hereditary hemolytic disorders are diverse, clinical, laboratory findings and complications overlap. A history of neonatal jaundice requiring phototherapy and exchange transfusion is quite usual. Mild to severe anemia may be accompanied with episodic or constant hemolysis associated with icterus, hyperbilirubinemia, growth retardation, gallstones, splenomegaly, and a variable degree of iron overload. Erythrocyte enzyme disorders should be suspected in patients with severe hemolytic episodes, or chronic hemolysis, after excluding hemoglobinopathies, membranopathies, and immune-mediated hemolysis.","PeriodicalId":118905,"journal":{"name":"The Journal of Pediatric Academy","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124953444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urinary Tract Infections in Children","authors":"H. Poyrazoğlu, Sibel Yel","doi":"10.51271/jpea-2021-0121","DOIUrl":"https://doi.org/10.51271/jpea-2021-0121","url":null,"abstract":"Urinary tract infections are one of the most common bacterial infections in children. It may cause severe complications in both acute and chronic periods. Escherichia coli is the most common microorganism that causes urinary tract infections in children. Recurrent urinary tract infection is a significant risk factor for kidney scarring. Early diagnosis and appropriate treatment of urinary tract infection, as well as determination of risk factors and prevention of recurrent urinary tract infections, should be the most critical goals in managing children with urinary tract infections.","PeriodicalId":118905,"journal":{"name":"The Journal of Pediatric Academy","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125410900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solitary Rectal Ulcer Syndrome in Children","authors":"D. Arslan, Buket Daldaban Sarıca","doi":"10.51271/jpea-2021-0103","DOIUrl":"https://doi.org/10.51271/jpea-2021-0103","url":null,"abstract":"To describe clinical features, demographic data, and complications of the patients with SRUS, which is a rare cause of rectal bleeding in children. Eleven patients diagnosed with Solitary Rectal Ulcer Syndrome (SRUS) were evaluated. The patients assessed by colonoscopy and the biopsies were investigated. The data evaluated in SPSS Program. The exact Method of the Chi-square test was used to compare groups according to qualitative variables. P <0.05 value was considered statistically significant. The most common symptom of the patients was rectal bleeding followed by abdominal pain and constipation. Lesions were mostly ulcerative in the endoscopic examination. There was a statistically significant relationship between the admission symptom and the response to treatment. Patients with abdominal pain and rectal bleeding had poor responses to treatment. In conclusion, SRUS is not uncommon than is thought in pediatric patients with the symptoms of rectal bleeding and constipation. SRUS should be considered in patients with or without rectal prolapse, with any complaints of any lesions in the rectum, hematochezia, and tenesmus.","PeriodicalId":118905,"journal":{"name":"The Journal of Pediatric Academy","volume":"33 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129126246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparison of Leak Synchronized Nasal SIMV Methods and Leak Compensated Nasal SIMV in Newborns with Respiratory Distress Syndrome","authors":"A. Özdemir, M. Akın, O. Baştuğ, T. Güneş","doi":"10.51271/jpea-2021-0094","DOIUrl":"https://doi.org/10.51271/jpea-2021-0094","url":null,"abstract":"The aim of the present study was to compare the efficacy of leak compensated nasal SIMV (LCnSIMV) and leak synchronized nasal SIMV (LSnSIMV) modes in order to reduce the need for endotracheal intubation and associated complications in newborns with respiratory distress. This randomized, prospective study was conducted on 50 infants (25 per group) with gestational age below 34 weeks and/or below 2000 grams who have been admitted to NICU of Erciyes University Hospital because of respiratory distress syndrome (RDS) and need for mechanical ventilation. Infants with congenital heart disease, nasopharyngeal pathology (coanal atresia and cleft palate-lip) were excluded. Infants monitored on mechanical ventilator after surfactant were randomly assigned to LCnSIMV and LSnSIMV groups before extubation. SPO2/FiO2 (S/F), peak heart rate (PHR), respiration rate per minute (RRM), and arterial blood pressure (aBP) values of patients were recorded. Gestational age, birth weight, gender, RDS, patent ductus arteriosus (PDA) requiring treatment, presence of intraventricular bleeding (IVH), retinopathy of prematurity (ROP), bronchopulmonary dysplasia (BPD), necrotizing enterocolitis (NEC) were recorded. The patients enrolled in the study were female by 48% and male by 52%. There was not any statistically significant difference between groups for gender, postnatal age and birth weight. There was detected statistically significant difference between LCnSIMV and LSnSIMV groups for non-invasive ventilation period and re-intubation rate (p=0.04 and p=0.03, respectively). There was detected statistically significant difference between LCnSIMV and LSnSIMV groups for SpO2 and S/F rates at 60 minutes (p=0.03 and p=0.01, respectively). There was not any difference between groups for blood pressure, PDA, IVH, ROP, BPD, NEC, sepsis and air leak. It may be appropriate to prefer the LSnSIMV method in patients with respiratory distress syndrome who need non-invasive ventilation in the pre-extubation period by considering the patient-ventilator compliance for positive effect in terms of mechanical clinical variables.","PeriodicalId":118905,"journal":{"name":"The Journal of Pediatric Academy","volume":"316 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128315151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}